Isaac S. Gomes-Filho,Pedro N. P. Santos,Simone S. Cruz,Ana C. M. G. Figueiredo,Soraya C. Trindade,Ana M. Ladeia,Eneida M. M. Cerqueira,Johelle S. Passos-Soares,Julita M. F. Coelho,Alexandre M. Hintz,Maurício L. Barreto,Ricardo G. Fischer,Peter M. Loomer,Frank A. Scannapieco
doi : 10.1002/JPER.21-0004
Volume 92, Issue 11 p. 1509-1521
Periodontitis and the Triglyceride/High Density Lipoprotein Cholesterol (TG/HDL-C) ratio have both been associated with cardiovascular disease, metabolic syndrome, and obesity. Additionally, the ratio is a possible substitute for predicting insulin resistance. This study investigated the association between periodontitis, its severity levels (exposures), and the TG/HDL-C ratio (outcome).
Andrea Ravidà,Maria Vera Rodriguez,Muhammad H. A. Saleh,Matthew Galli,Musa Qazi,Giuseppe Troiano,Hom-Lay Wang,Pablo Galindo Moreno
doi : 10.1002/JPER.21-0012
Volume 92, Issue 11 p. 1522-1535
The aim of this study was to determine if a previous history of periodontitis according to the preset definitions of the 2017 World Workshop is correlated with increased implant failure, and occurrence and severity of peri-implantitis (PI).
Yvonne Jockel-Schneider,Ulrich Schlagenhauf,Peggy Stölzel,Sophia Goßner,Reinhold Carle,Benjamin Ehmke,Karola Prior,Daniel Hagenfeld
doi : 10.1002/JPER.20-0778
Volume 92, Issue 11 p. 1536-1545
This follow-up study evaluated microbiome changes in periodontal recall patients after consuming a nitrate-rich diet that led to a marked decrease of gingival inflammation.
Kaining Liu,Zhen Huang,Zhibin Chen,Bing Han,Xiangying Ouyang
doi : 10.1002/JPER.20-0860
Volume 92, Issue 11 p. 1546-1553
To investigate the regenerative effect of adjunctive use of guided tissue regeneration (GTR), bovine porous bone mineral (BPBM), and platelet-rich fibrin (PRF) in intrabony defects.
Casey D. Wright,Brenda Heaton,Daniel W. McNeil
doi : 10.1002/JPER.20-0066
Volume 92, Issue 11 p. 1554-1563
Self-report measures of periodontal disease have utility for screening, but have not capitalized on a latent variable approach based on psychometric theory to validate such measures. This study aimed to develop a psychometrically valid self-report measure of periodontal disease using latent variable factor analysis and other evidence-based psychometric analyses.
Jun-Beom Lee,Seoyoon Chu,Heithem Ben Amara,Hyun-Young Song,Min-Jung Son,Jungwon Lee,Hae-Young Kim,Ki-Tae Koo,In-Chul Rhyu
doi : 10.1002/JPER.20-0832
Volume 92, Issue 11 p. 1564-1575
The aim of this study was to evaluate the efficacy of deproteinized bovine bone mineral with 10% collagen (DBBM-C) soaked with hyaluronic acid (HA) for ridge preservation in compromised extraction sockets.
Imena Rexhepi,Michele Paolantonio,Luigi Romano,Matteo Serroni,Pasquale Santamaria,Lorenzo Secondi,Giulia Paolantonio,Bruna Sinjari,Paolo De Ninis,Beatrice Femminella
doi : 10.1002/JPER.20-0305
Volume 92, Issue 11 p. 1576-1587
Growing evidence shows the efficacy of platelet concentrates in periodontal therapy. This study aimed to demonstrate that an inorganic bovine bone graft (IBB) in combination with a leukocyte and platelet rich fibrin (L-PRF) is non-inferior to a combination with a collagen membrane (CM) when managing unfavorable infrabony defects (IBDs).
Laís Christina P. Espíndola,Marcus Vinícius M. R. do Nascimento,Renata M. do Souto,Ana Paula V. Colombo
doi : 10.1002/JPER.20-0815
Volume 92, Issue 11 p. 1588-1600
This study evaluated the prevalence, virulence and antimicrobial susceptibility of enterococci isolated from the subgingival microbiota of patients with different periodontal status.
Yongmei Deng,Songlin He,Jinhua Wang
doi : 10.1002/JPER.20-0756
Volume 92, Issue 11 p. 1601-1612
To investigate the psychometric properties of the Hospital Anxiety and Depression Scale (HADS) and 10-item Perceived Stress Scale (PSS-10) in patients with periodontitis and to evaluate the psychological features of patients with periodontitis.
Hani S. AlMoharib,Bjorn Steffensen,Driss Zoukhri,Matthew Finkelman,Robert Gyurko
doi : 10.1002/JPER.20-0765
Volume 92, Issue 11 p. 1613-1621
Emergence of peri-implant diseases led to the development of various methods for implant surface decontamination. This study was designed to compare the efficacy of biofilm removal from implant-like titanium surfaces by an erbium-doped yttrium-aluminum-garnet (Er:YAG) laser, titanium brush, and carbon fiber curet.
Lan-Yun Chang,Chao-Han Lai,Cheng-Hsiang Kuo,Bi-Ing Chang,Hua-Lin Wu,Tsung-Lin Cheng
doi : 10.1002/JPER.20-0732
Volume 92, Issue 11 p. 1622-1634
Evidence demonstrates that the thrombomodulin (TM) lectin domain (TMD1) exerts anti-inflammatory functions. Lipopolysaccharides derived from Porphyromonas gingivalis (Pg-LPS) are considered a major pathogenic factor for chronic periodontitis, promoting inflammation, osteoclastogenesis and alveolar bone resorption. Herein, we aimed to evaluate the potential therapeutic effect of recombinant TMD1 (rTMD1) in suppression of Pg-LPS-induced osteoclastogenesis and periodontal bone loss.
Chiaki Morimoto,Masahide Takedachi,Kohsuke Kawasaki,Junpei Shimomura,Mari Murata,Asae Hirai,Kazuma Kawakami,Keigo Sawada,Tomoaki Iwayama,Shinya Murakami
doi : 10.1002/JPER.20-0670
Volume 92, Issue 11 p. 1635-1645
Cellular responses to hypoxia regulate various biological events, including angiogenesis and extracellular matrix metabolism. Collagen is a major component of the extracellular matrix in periodontal tissues and its coordinated production is essential for tissue homeostasis. In this study, we investigated the effects of hypoxia on collagen production in human gingival fibroblasts (HGFs) and human periodontal ligament cells (HPDLs).
Henrique R. Matheus,Edilson Ervolino,David Jonathan Rodrigues Gusman,Breno Edson Sendão Alves,Luiz Guilherme Fiorin,Priscilla Aparecida Pereira,Juliano Milanezi de Almeida
doi : 10.1002/JPER.20-0613
Volume 92, Issue 11 p. 1646-1658
This study is designed to evaluate the potential of different formulations of hyaluronic acid (HA) to improve new bone formation in critical-size calvaria defect (CSD) when combined with a deproteinized bovine graft (DBG) material.
Li Zhang,Lei Cheng,Yujia Cui,Zuping Wu,Linyi Cai,Liu Yang,Mengmeng Duan,Demao Zhang,Chenchen Zhou,Jing Xie
doi : 10.1002/JPER.20-0869
Volume 92, Issue 11 p. e103-e115
GroEL, a bacterial metabolite, is an important stimulator of inflammation. The aim of this study is to confirm the effect of the virulence factor GroEL on differentiation potential of periodontal ligament (PDL) stem cells (PDLSCs) and the potential mechanisms.
Elis J. Lira dos Santos,Cristiane R. Salmon,Michael B. Chavez,Amanda B. de Almeida,Michelle H. Tan,Emily Y. Chu,Enilson A. Sallum,Marcio Z. Casati,Karina G. S. Ruiz,Kamila R. Kantovitz,Brian L. Foster,Francisco H. Nociti Júnior
doi : 10.1002/JPER.21-0119
Volume 92, Issue 11 p. e116-e127
Cellular cementum, a mineralized tissue covering apical tooth roots, grows by apposition to maintain the tooth in its occlusal position. We hypothesized that resident cementocytes would show morphological changes in response to cementum apposition, possibly implicating a role in cementum biology.
Yuhui Yang,Yiping Huang,Hao Liu,Yunfei Zheng,Lingfei Jia,Weiran Li
doi : 10.1002/JPER.20-0806
Volume 92, Issue 11 p. e128-e138
Migration of cementoblasts to resorption lacunae is the foundation for repairing root resorption during orthodontic tooth movement. Previous studies reported that autophagy was activated by compression in periodontal ligament cells. The aim of this study was to investigate the migration of cementoblasts and determine whether autophagy is involved in the regulation of cementoblast migration under compressive force.
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