Diabetes




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سفارش

ATP-Sensitive Potassium Channels in Hyperinsulinism and Type 2 Diabetes: Inconvenient Paradox or New Paradigm?

Colin G. Nichols; Nathaniel W. York; Maria S. Remedi

doi : 10.2337/db21-0755

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Imeglimin to the Rescue: Enhanced CHOP/GADD34/eIF2α Signaling Axis Promotes β-Cell Survival

Seokwon Jo; Emilyn U. Alejandro

doi : 10.2337/dbi21-0035

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The Need to Increase Clinical Skills and Change the Genetic Testing Strategy for Monogenic Diabetes

Rosa Di Paola; Antonella Marucci; Vincenzo Trischitta

doi : 10.2337/dbi21-0037

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Adipose Tissue Inflammation Is Not Related to Adipose Insulin Resistance in Humans

Ana Elena Espinosa De Ycaza; Esben Søndergaard; Maria Morgan-Bathke; Kelli Lytle; Danae A. Delivanis; Paola Ramos; Barbara Gisella Carranza Leon; Michael D. Jensen

doi : 10.2337/db21-0609

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Obesity-Induced miR-455 Upregulation Promotes Adaptive Pancreatic β-Cell Proliferation Through the CPEB1/CDKN1B Pathway

Qianxing Hu; Jinming Mu; Yuhong Liu; Yue Yang; Yue Liu; Yi Pan; Yanfeng Zhang; Ling Li; Dechen Liu; Jianqiu Chen; Fangfang Zhang; Liang Jin

doi : 10.2337/db21-0134

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A Cycle of Inflammatory Adipocyte Death and Regeneration in Murine Adipose Tissue

Akio Monji; Yang Zhang; G.V. Naveen Kumar; Christelle Guillermier; Soomin Kim; Benjamin Olenchock; Matthew L. Steinhauser

doi : 10.2337/db20-1306

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Imeglimin Ameliorates β-Cell Apoptosis by Modulating the Endoplasmic Reticulum Homeostasis Pathway

Jinghe Li; Ryota Inoue; Yu Togashi; Tomoko Okuyama; Aoi Satoh; Mayu Kyohara; Kuniyuki Nishiyama; Takahiro Tsuno; Daisuke Miyashita; Tatsuya Kin; A.M. James Shapiro; Resilind Su Ern Chew; Adrian Kee Keong Teo; Seiichi Oyadomari; Yasuo Terauchi; Jun Shirakawa

doi : 10.2337/db21-0123

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The Role of TRAPγ/SSR3 in Preproinsulin Translocation Into the Endoplasmic Reticulum

Xiaoxi Xu; Yumeng Huang; Xin Li; Peter Arvan; Ming Liu

doi : 10.2337/db21-0638

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Nutrient Sensor mTORC1 Regulates Insulin Secretion by Modulating β-Cell Autophagy

Tal Israeli; Yael Riahi; Perla Garzon; Ruy Andrade Louzada; Joao Pedro Werneck-de-Castro; Manuel Blandino-Rosano; Roni Yeroslaviz-Stolper; Liat Kadosh; Sharona Tornovsky-Babeay; Gilad Hacker; Nitzan Israeli; Orly Agmon; Boaz Tirosh; Erol Cerasi; Ernesto Bernal-Mizrachi; Gil Leibowitz

doi : 10.2337/db21-0281

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Endosomal Sequestration of TLR4 Antibody Induces Myeloid-Derived Suppressor Cells and Reverses Acute Type 1 Diabetes

Kathryn C.S. Locker; Kritika Kachapati; Yuehong Wu; Kyle J. Bednar; David Adams; Caroline Patel; Hiroki Tsukamoto; Luke S. Heuer; Bruce J. Aronow; Andrew B. Herr; William M. Ridgway

doi : 10.2337/db21-0426

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Tolerogenic Delivery of a Hybrid Insulin Peptide Markedly Prolongs Islet Graft Survival in the NOD Mouse

Braxton L. Jamison; James E. DiLisio; K. Scott Beard; Tobias Neef; Brenda Bradley; Jessica Goodman; Ronald G. Gill; Stephen D. Miller; Rocky L. Baker; Kathryn Haskins

doi : 10.2337/db20-1170

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Seroreactivity Against Tyrosine Phosphatase PTPRN Links Type 2 Diabetes and Colorectal Cancer and Identifies a Potential Diagnostic and Therapeutic Target

María Garranzo-Asensio; Guillermo Solís-Fernández; Ana Montero-Calle; José Manuel García-Martínez; Maria Carmen Fiuza; Pilar Pallares; Nuria Palacios-Garcia; Custodia García-Jiménez; Ana Guzman-Aranguez; Rodrigo Barderas

doi : 10.2337/db20-1206

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SGLT2 Inhibition Increases Fasting Glucagon but Does Not Restore the Counterregulatory Hormone Response to Hypoglycemia in Participants With Type 1 Diabetes

Schafer C. Boeder; Justin M. Gregory; Erin R. Giovannetti; Jeremy H. Pettus

doi : 10.2337/db21-0769

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Clinical Predictors and Long-term Impact of Acute Kidney Injury on Progression of Diabetic Kidney Disease in Chinese Patients With Type 2 Diabetes

Guozhi Jiang; Andrea O. Luk; Claudia H.T. Tam; Risa Ozaki; Cadmon K.P. Lim; Elaine Y.K. Chow; Eric S. Lau; Alice P.S. Kong; Baoqi Fan; Hong Kong Diabetes Register TRS Study Group; Ka Fai Lee; Shing Chung Siu; Grace Hui; Chiu Chi Tsang; Kam Piu Lau; Jenny Y. Leung; Man-wo Tsang; Grace Kam; Ip Tim Lau; June K. Li; Vincent T. Yeung; Emmy Lau; Stanley Lo; Samuel Fung; Yuk Lun Cheng; Chun Chung Chow; Hong Kong Diabetes Biobank Study Group; Nelson L.S. Tang; Yu Huang; Hui-yao Lan; Richard A. Oram; Cheuk Chun Szeto; Wing Yee So; Juliana C.N. Chan; Ronald C.W. Ma

doi : 10.2337/db21-0694

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Syndromic Monogenic Diabetes Genes Should Be Tested in Patients With a Clinical Suspicion of Maturity-Onset Diabetes of the Young

Kevin Colclough; Sian Ellard; Andrew Hattersley; Kashyap Patel

doi : 10.2337/db21-0517

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Functional Gly297Ser Variant of the Physiological Dysglycemic Peptide Pancreastatin Is a Novel Risk Factor for Cardiometabolic Disorders

Prasanna K.R. Allu; Malapaka Kiranmayi; Sromona D. Mukherjee; Venkat R. Chirasani; Richa Garg; Durairajpandian Vishnuprabu; Sudesh Ravi; Lakshmi Subramanian; Bhavani S. Sahu; Dhanya R. Iyer; Sakthisree Maghajothi; Saurabh Sharma; Marimuthu S. Ravi; Madhu Khullar; Arasambattu K. Munirajan; Jiaur R. Gayen; Sanjib Senapati; Ajit S. Mullasari; Viswanathan Mohan; Venkatesan Radha; Sathyamangala V. Naga Prasad; Nitish R. Mahapatra

doi : 10.2337/db21-0289

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Recessive Genome-Wide Meta-analysis Illuminates Genetic Architecture of Type 2 Diabetes

Mark J. O’Connor; Philip Schroeder; Alicia Huerta-Chagoya; Paula Cortés-Sánchez; Silvía Bonàs-Guarch; Marta Guindo-Martínez; Joanne B. Cole; Varinderpal Kaur; David Torrents; Kumar Veerapen; Niels Grarup; Mitja Kurki; Carsten F. Rundsten; Oluf Pedersen; Ivan Brandslund; Allan Linneberg; Torben Hansen; Aaron Leong; Jose C. Florez; Josep M. Mercader

doi : 10.2337/db21-0545

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Cytotoxicity-Related Gene Expression and Chromatin Accessibility Define a Subset of CD4+ T Cells That Mark Progression to Type 1 Diabetes

Naiara G. Bediaga; Alexandra L. Garnham; Gaetano Naselli; Esther Bandala-Sanchez; Natalie L. Stone; Joanna Cobb; Jessica E. Harbison; John M. Wentworth; Annette-G. Ziegler; Jennifer J. Couper; Gordon K. Smyth; Leonard C. Harrison

doi : 10.2337/db21-0612

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Gene Panel Sequencing of Patients With Monogenic Diabetes Brings to Light Genes Typically Associated With Syndromic Presentations

Cécile Saint-Martin; Delphine Bouvet; Mathilda Bastide; Christine Bellanné-Chantelot; on behalf of the Monogenic Diabetes Study Group of the Société Francophone du Diabète*

doi : 10.2337/db21-0520

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Comment on De Wendt et al. Contraction-Mediated Glucose Transport in Skeletal Muscle Is Regulated by a Framework of AMPK, TBC1D1/4, and Rac1. Diabetes 2021;70:2796–2809

Rasmus Kjøbsted; Jørgen F.P. Wojtaszewski

doi : 10.2337/db21-1036

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Response to Comment on Wendt et al. Contraction-Mediated Glucose Transport in Skeletal Muscle Is Regulated by a Framework of AMPK, TBC1D1/4, and Rac1. Diabetes 2021;70:2796–2809

Alexandra Chadt; Hadi Al-Hasani

doi : 10.2337/dbi21-0038

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