Diabetes




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سفارش

A Special Thanks to the Reviewers of Diabetes

David A. D’Alessio, MD

doi : 10.2337/db22-en04

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When Adipose Tissue Lets You Down: Understanding the Functions of Genes Disrupted in Lipodystrophy

Justin J. Rochford

doi : 10.2337/dbi21-0006

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Keeping It Local in Metabolic Disease: Adipose Tissue Paracrine Signaling and Insulin Resistance

Darcy E. Kahn; Bryan C. Bergman

doi : 10.2337/dbi21-0020

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Screening for Type 1 Diabetes in the General Population: A Status Report and Perspective

Emily K. Sims; Rachel E.J. Besser; Colin Dayan; Cristy Geno Rasmussen; Carla Greenbaum; Kurt J. Griffin; William Hagopian; Mikael Knip; Anna E. Long; Frank Martin; Chantal Mathieu; Marian Rewers; Andrea K. Steck; John M. Wentworth; Stephen S. Rich; Olga Kordonouri; Anette-Gabriele Ziegler; Kevan C. Herold; for the NIDDK Type 1 Diabetes TrialNet Study Group

doi : 10.2337/dbi20-0054

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Glutamine Regulates Skeletal Muscle Immunometabolism in Type 2 Diabetes

Lucile Dollet; Michael Kuefner; Elena Caria; David Rizo-Roca; Logan Pendergrast; Ahmed M. Abdelmoez; Håkan K.R. Karlsson; Marie Bjrnholm; Emilie Dalbram; Jonas T. Treebak; Jun Harada; Erik Näslund; Mikael Rydén; Juleen R. Zierath; Nicolas J. Pillon; Anna Krook

doi : 10.2337/db20-0814

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Lactate Is a Key Mediator That Links Obesity to Insulin Resistance via Modulating Cytokine Production From Adipose Tissue

Yijun Lin; Meijuan Bai; Shuo Wang; Lingling Chen; Zixuan Li; Chenchen Li; Peijuan Cao; Yan Chen

doi : 10.2337/db21-0535

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PTPN2 Regulates the Interferon Signaling and Endoplasmic Reticulum Stress Response in Pancreatic β-Cells in Autoimmune Diabetes

Bernat Elvira; Valerie Vandenbempt; Julia Bauzá-Martinez; Raphaël Crutzen; Javier Negueruela; Hazem Ibrahim; Matthew L. Winder; Manoja K. Brahma; Beata Vekeriotaite; Pieter-Jan Martens; Sumeet Pal Singh; Fernando Rossello; Pascale Lybaert; Timo Otonkoski; Conny Gysemans; Wei Wu; Esteban N. Gurzov

doi : 10.2337/db21-0443

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Genetic Predictors of Change in Waist Circumference and Waist-to-Hip Ratio With Lifestyle Intervention: The Trans-NIH Consortium for Genetics of Weight Loss Response to Lifestyle Intervention

Jeanne M. McCaffery; Kathleen A. Jablonski; Qing Pan; Arne Astrup; Malene Revsbech Christiansen; Dolores Corella; Lauren M.L. Corso; Jose C. Florez; Paul W. Franks; Christopher Gardner; Torben Hansen; Tuomas O. Kilpeläinen; William C. Knowler; Jaana Lindström; Wim H.M. Saris; Thorkild I.A. Sørensen; Jaakko Tuomilehto; Matti Uusitupa; Rena R. Wing; Tanya Agurs-Collins

doi : 10.2337/db21-0741

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Adipocyte-Specific Modulation of KLF14 Expression in Mice Leads to Sex-Dependent Impacts on Adiposity and Lipid Metabolism

Qianyi Yang; Jameson Hinkle; Jordan N. Reed; Redouane Aherrahrou; Zhiwen Xu; Thurl E. Harris; Erin J. Stephenson; Kiran Musunuru; Susanna R. Keller; Mete Civelek

doi : 10.2337/db21-0674

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Rare Variant Analysis of Obesity-Associated Genes in Young Adults With Severe Obesity From a Consanguineous Population of Pakistan

Sadia Saeed; Qasim M. Janjua; Attiya Haseeb; Roohia Khanam; Emmanuelle Durand; Emmanuel Vaillant; Lijiao Ning; Alaa Badreddine; Lionel Berberian; Mathilde Boissel; Souhila Amanzougarene; Mickaël Canouil; Mehdi Derhourhi; Amélie Bonnefond; Muhammad Arslan; Philippe Froguel

doi : 10.2337/db21-0373

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Hyperglycemia and Not Hyperinsulinemia Mediates Diabetes-Induced Memory CD8 T-Cell Dysfunction

Inga Kavazović; Mia Krapić; Ammarina Beumer-Chuwonpad; Bojan Polić; Tamara Turk Wensveen; Niels A. Lemmermann; Klaas P.J.M. van Gisbergen; Felix M. Wensveen

doi : 10.2337/db21-0209

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Immune and Metabolic Effects of Antigen-Specific Immunotherapy Using Multiple β-Cell Peptides in Type 1 Diabetes

Yuk-Fun Liu; Jake Powrie; Sefina Arif; Jennie H.M. Yang; Evangelia Williams; Leena Khatri; Mamta Joshi; Loic Lhuillier; Nikolaos Fountoulakis; Emma Smith; Craig Beam; Anna Lorenc; Mark Peakman; Timothy Tree

doi : 10.2337/db21-0728

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Differentiating Microaneurysm Pathophysiology in Diabetic Retinopathy Through Objective Analysis of Capillary Nonperfusion, Inflammation, and Pericytes

Dong An; Bryan Tan; Dao-Yi Yu; Chandrakumar Balaratnasingam

doi : 10.2337/db21-0737

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Pathogenic Role of Diabetes-Induced Overexpression of Kallistatin in Corneal Wound Healing Deficiency Through Inhibition of Canonical Wnt Signaling

Wentao Liang; Li Huang; Xiang Ma; Lijie Dong; Rui Cheng; Marcus Dehdarani; Dimitrios Karamichos; Jian-xing Ma

doi : 10.2337/db21-0740

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Single-Cell Transcriptomics Reveals Novel Role of Microglia in Fibrovascular Membrane of Proliferative Diabetic Retinopathy

Zizhong Hu; Xiying Mao; Mingkang Chen; Xinjing Wu; Tianye Zhu; Yu Liu; Zhengyu Zhang; Wen Fan; Ping Xie; Songtao Yuan; Qinghuai Liu

doi : 10.2337/db21-0551

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GPR40 Activation Abolishes Diabetes-Induced Painful Neuropathy by Suppressing VEGF-A Expression

Vanessa Königs; Sandra Pierre; Martin Schicht; Jessica Welss; Lisa Hahnefeld; Vittoria Rimola; Elke Lütjen-Drecoll; Gerd Geisslinger; Klaus Scholich

doi : 10.2337/db21-0711

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Hyperglycemia, Reduced Hematopoietic Stem Cells, and Outcome of COVID-19

Benedetta Maria Bonora; Paola Fogar; Jenny Zuin; Daniele Falaguasta; Roberta Cappellari; Annamaria Cattelan; Serena Marinello; Anna Ferrari; Angelo Avogaro; Mario Plebani; Daniela Basso; Gian Paolo Fadini

doi : 10.2337/db21-0965

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Methazolamide Attenuates the Development of Diabetic Cardiomyopathy by Promoting β-Catenin Degradation in Type 1 Diabetic Mice

Xiaoqing Chen; Yilang Li; Xun Yuan; Wenchang Yuan; Conglin Li; Yue Zeng; Yuling Lian; Xiaoxia Qiu; Yuan Qin; Guiping Zhang; Xiawen Liu; Chengfeng Luo; Jian-Dong Luo; Ning Hou

doi : 10.2337/db21-0506

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Randomized Controlled Trial of the Hemodynamic Effects of Empagliflozin in Patients With Type 2 Diabetes at High Cardiovascular Risk: The SIMPLE Trial

Emil Wolsk; Mikkel Jürgens; Morten Schou; Mads Ersbøll; Philip Hasbak; Andreas Kjær; Bo Zerahn; Niels Høgh Brandt; Peter Haulund Gæde; Peter Rossing; Jens Faber; Silvio E. Inzucchi; Caroline Michaela Kistorp; Finn Gustafsson

doi : 10.2337/db21-0721

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Babies of South Asian and European Ancestry Show Similar Associations With Genetic Risk Score for Birth Weight Despite the Smaller Size of South Asian Newborns

Suraj S. Nongmaithem; Robin N. Beaumont; Akshay Dedaniya; Andrew R. Wood; Babatunji-William Ogunkolade; Zahid Hassan; Ghattu V. Krishnaveni; Kalyanaraman Kumaran; Ramesh D. Potdar; Sirazul A. Sahariah; Murali Krishna; Chiara Di Gravio; Inder D. Mali; Alagu Sankareswaran; Akhtar Hussain; Biswajit W. Bhowmik; Abdul Kalam A. Khan; Bridget A. Knight; Timothy M. Frayling; Sarah Finer; Caroline H.D. Fall; Chittaranjan S. Yajnik; Rachel M. Freathy; Graham A. Hitman; Giriraj R. Chandak

doi : 10.2337/db21-0479

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Sulfated Progesterone Metabolites That Enhance Insulin Secretion via TRPM3 Are Reduced in Serum From Women With Gestational Diabetes Mellitus

Hei Man Fan; Alice L. Mitchell; Elena Bellafante; Saraid McIlvride; Laura I. Primicheru; Mirko Giorgi; Ivano Eberini; Argyro Syngelaki; Anita Lövgren-Sandblom; Peter Jones; David McCance; Nithya Sukumar; Nishanthi Periyathambi; Yonas Weldeselassie; Katharine F. Hunt; Kypros H. Nicolaides; David Andersson; Stuart Bevan; Paul T. Seed; Gavin A. Bewick; James E. Bowe; Franca Fraternali; Ponnusamy Saravanan; Hanns-Ulrich Marschall; Catherine Williamson

doi : 10.2337/db21-0702

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Monocyte miRNAs Are Associated With Type 2 Diabetes

Daniel C. Parker; Ma Wan; Kurt Lohman; Li Hou; Anh Tram Nguyen; Jingzhong Ding; Alain Bertoni; Steve Shea; Gregory L. Burke; David R. Jacobs, Jr.; Wendy Post; David Corcoran; Ina Hoeschele; John S. Parks; Yongmei Liu

doi : 10.2337/db21-0704

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Spatial Environment Affects HNF4A Mutation-Specific Proteome Signatures and Cellular Morphology in hiPSC-Derived β-Like Cells

Manuel Carrasco; Chencheng Wang; Anne M. Søviknes; Yngvild Bjørlykke; Shadab Abadpour; Joao A. Paulo; Erling Tjora; Pål Njølstad; Jonas Ghabayen; Ingrid Nermoen; Valeriya Lyssenko; Simona Chera; Luiza M. Ghila; Marc Vaudel; Hanne Scholz; Helge Ræder

doi : 10.2337/db20-1279

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Erratum. Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes. Diabetes 2021;70:2580–2594

Maroof Alam; Anoop Arunagiri; Leena Haataja; Mauricio Torres; Dennis Larkin; John Kappler; Niyun Jin; Peter Arvan

doi : 10.2337/db22-er04a

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Comment On Espinosa De Ycaza et al. Adipose Tissue Inflammation Is Not Related to Adipose Insulin Resistance in Humans. Diabetes 2022;71:381–393

Inez Trouwborst; Gijs H. Goossens

doi : 10.2337/db21-1141

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Response to Comment on Espinosa De Ycaza et al. Adipose Tissue Inflammation Is Not Related to Adipose Insulin Resistance in Humans. Diabetes 2022;71:381–393

Ana Elena Espinosa De Ycaza; Esben Søndergaard; Michael D. Jensen

doi : 10.2337/dbi22-0005

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