Journal of Allergy and Clinical Immunology




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doi : 10.1016/S0091-6749(21)02688-9

Volume 149, Issue 2, February 2022, Page OFC

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Recent advances in the immunopathogenesis of severe asthma

SabaAl HeialyPhDabRakhee K.RamakrishnanPhDcdQutaybaHamidMD, PhDbd

doi : 10.1016/j.jaci.2021.12.765

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Recent advances in the immunopathogenesis of severe asthma

doi : 10.1016/j.jaci.2021.12.770

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TH17 cells and corticosteroid insensitivity in severe asthma

YanXieMD, PhDaPeter W.AbelPhDaThomas B.CasaleMDbYapingTuPhDa

doi : 10.1016/j.jaci.2021.12.769

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Considering biomarkers in asthma disease severity

AdnanCustovicMD, PhD, FMedSciaSalmanSiddiquiFRCP, MD, PhDbSejalSaglaniFRCPCH, MDa

doi : 10.1016/j.jaci.2021.11.021

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The Precision Interventions for Severe and/or Exacerbation-Prone (PrecISE) Asthma Network: An overview of Network organization, procedures, and interventions

Steve N.GeorasMDaRosalind J.WrightMD, MPHbAnastasiaIvanovaPhDcElliotIsraelMDdLisa M.LaVangePhDcPraveenAkuthotaMDeTara F.CarrMDfLoren C.DenlingerMD, PhDgMerritt L.FajtMDhRajeshKumarMD, MSiWanda K.O’NealPhD, MDjWandaPhipatanakulMD, MSkStanley J.SzeflerMDlmMark A.AronicaMDnLeonard B.BacharierMDoAllison J.BurbankMDjMarioCastroMD, MPHpLauraCrotty AlexanderMDe…NicoleWilsonMS

doi : 10.1016/j.jaci.2021.10.035

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2021 year in review: Spotlight on eosinophils

Julia L.M.DunnPhDMarc E.RothenbergMD, PhD

doi : 10.1016/j.jaci.2021.11.012

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News Beyond Our Pages

Marc E.RothenbergMD, PhD∗JeanBousquetMD∗

doi : 10.1016/j.jaci.2021.12.776

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Microbiome-immune interactions and relationship to asthma severity

JuanTrujilloMD, MScaNonhlanhlaLunjaniMDbcDermotRyanMD, FRCGPdLiamO’MahonyPhDbef

doi : 10.1016/j.jaci.2021.12.774

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Moving beyond medication: Assessment and interventions on environmental and social determinants are needed to reduce severe asthma

ErikaGarciaPhDFrankGillilandMD, PhD

doi : 10.1016/j.jaci.2021.12.760

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Immune checkpoint skewing might be the cause of continuous immune activation in nasal polyps: New opportunities for therapies

AlexKleinJanPhD

doi : 10.1016/j.jaci.2021.11.003

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The importance of using core outcome measures during therapeutic studies of eosinophilic esophagitis

David A.HillMD, PhD

doi : 10.1016/j.jaci.2021.09.025

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The new quest in CTLA-4 insufficiency: How to immune modulate effectively?

EmmaWestermann-ClarkMD, MAabMarkBallowMDbcJolan E.WalterMD, PhDbcd

doi : 10.1016/j.jaci.2021.11.020

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Μένος: Power, life force, and purpose in mentoring

Kathleen E.SullivanMD, PhD

doi : 10.1016/j.jaci.2021.10.032

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Severe COVID-19 is associated with hyperactivation of the alternative complement pathway

JeremyBoussierPhDaNaderYatimMD, PhDbcArmanceMarchalMDdJérômeHadjadjMD, PhDbeBrunoCharbitMScfCarineEl SissyMDdNicolasCarlierMDgFrédéricPèneMD, PhDhiLucMouthonMD, PhDbiPierre-LouisTharauxMD, PhDjAnneBergeronMD, PhDkDavid M.SmadjaMD, PhDlmnFrédéricRieux-LaucatPhDeDarraghDuffyPhDcfSolenKernéisMD PhDopVéroniqueFrémeaux-BacchiMD, PhDdBenjaminTerrierMD, PhDbj

doi : 10.1016/j.jaci.2021.11.004

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Treatment of chronic or relapsing COVID-19 in immunodeficiency

Li-An K.BrownMRCPabEdMoranPhDcAnnaGoodmanDPhildHelenBaxendalePhDeWilliamBerminghamMBBSfMatthewBucklandPhDghImanAbdulKhaliqMBBSiHannahJarvisMBBSjMichaelHunterFRCPkSurendraKaranamFRCPathlAishaPatelMBBSbMeganJenkinsMBBScAlexanderRobbinsMBBSmSujoyKhanFRCPathnThomasSimpsonMBBSoStephenJollesMD, PhDpJonathanUnderwoodPhDqrSinisaSavicPhDst…David M.LowePhDaj

doi : 10.1016/j.jaci.2021.10.031

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Asthma and atopy in COVID-19: 2021 updates

Tara F.CarrMDMonicaKraftMD

doi : 10.1016/j.jaci.2021.12.762

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Immune health grades: Finding resilience in the COVID-19 pandemic and beyond

Vincent C.MarconiMDaVenkateshKrishnanPhDbE. WesleyElyMD, MPHcdMontyMontanoPhDe

doi : 10.1016/j.jaci.2021.10.025

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Advances in clinical outcomes: What we have learned during the COVID-19 pandemic

AmerAl-MusaMDBrennaLaBereMDSaddiqHabiballahMDAlan A.NguyenMDJanetChouMD

doi : 10.1016/j.jaci.2021.12.775

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Real-time imaging of asthmatic epithelial cells identifies migratory deficiencies under type-2 conditions

MingzhuJinMDabSimonWatkinsPhDcYolandaLarribaPhDdCallenWallacePhDcClaudetteSt. CroixPhDcXiuxiaZhouPhDaJinmingZhaoPhDaShyamalPeddadaPhDeSally E.WenzelMDaf

doi : 10.1016/j.jaci.2021.08.027

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Neuroimaging and biomarker evidence of neurodegeneration in asthma

Melissa A.RosenkranzPhDabDouglas C.DeanIIIPhDcdeBarbara B.BendlinPhDfhNizar N.JarjourMDfStephaneEsnaultPhDfHenrikZetterbergMD, PhDijklAmandaHeslegravePhDlMichael D.EvansMSmRichard J.DavidsonPhDabgWilliam W.BusseMDf

doi : 10.1016/j.jaci.2021.09.010

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IL-17A–producing sinonasal MAIT cells in patients with chronic rhinosinusitis with nasal polyps

Min-SeokRhaMD, PhDabYoung HoonYoonMD, PhDcJune-YoungKohMDaJae HyungJungBScaHa SeokLeeMDaSoo KyoungParkMD, PhDcSu-HyungParkPhDaYong MinKimMD, PhDcdKi-SangRhaMD, PhDcEui-CheolShinMD, PhDa

doi : 10.1016/j.jaci.2021.07.037

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Extrafollicular PD-1highCXCR5–CD4+ T cells participate in local immunoglobulin production in nasal polyps

Zhi-ChaoWangMD, PhDa∗YinYaoMD, PhDa∗Cai-LingChenMDaCui-LianGuoMD, PhDaHong-XiaDingMDaJiaSongMD, PhDaZhe-ZhengWangMDaNanWangMD, PhDaXue-LiLiMDaBoLiaoMD, PhDaYangYangPhDbDiYuPhDbZhengLiuMD, PhDa

doi : 10.1016/j.jaci.2021.06.023

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Single-cell analysis reveals innate lymphoid cell lineage infidelity in atopic dermatitis

NataliaAlkonMSca∗Wolfgang M.BauerMDa∗ThomasKrausgruberPhDbIssacGohBSccJohannesGrissMD, PhDaVyNguyenMScaBaerbelReiningeraChristineBangertMDaClementStaudMDdPatrick M.BrunnerMD, MScaChristophBockPhDbeMuzlifahHaniffaMD, PhDcfgGeorgStinglMDa

doi : 10.1016/j.jaci.2021.07.025

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Cytokine responses in nonlesional psoriatic skin as clinical predictor to anti-TNF agents

Lam C.TsoiPhDabcMatthew T.PatrickPhDaShaoShuaiMDadMrinal K.SarkarPhDaSunyiChiBSacBethanyRuffinoBSaAllison C.BilliMD, PhDaXianyingXingMDaRanjithaUppalaBSaChengZangPhDaJosephFullmerBSaZhiHePhDcEmanualMaverakisMDeNehal N.MehtaMDfBethany E.Perez WhitePhDgSpiroGetsiosPhDgYolandaHelfrichMDaJohn J.VoorheesMDa…Johann E.GudjonssonMD, PhDa

doi : 10.1016/j.jaci.2021.07.024

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Tolerance development in cow’s milk–allergic infants receiving amino acid–based formula: A randomized controlled trial

PantipaChatchateeMDaAnnaNowak-WegrzynMD, PhDbcLarsLangeMDdSuwatBenjaponpitakMDeKok WeeChongMDfPasureeSangsupawanichMDgMarleen T.J.van AmptingPhDhManon M.Oude NijhuisPhDhLucien F.HarthoornPhDhJane E.LangfordPhDhJanKnolPhDhiKarenKnippingMSchJohanGarssenPhDhjValerieTrendelenburgPhDkRobertPesekMDlCarla M.DavisMDmAntonellaMuraroMDnMichErlewyn-LajeunesseMDo…Boner

doi : 10.1016/j.jaci.2021.06.025

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Development of a core outcome set for therapeutic studies in eosinophilic esophagitis (COREOS)

The COREOS Collaborators:ChristopherMaMD, MPHabAlain M.SchoepferMDcEvan S.DellonMD, MPHdAlbert J.BredenoordMD, PhDeMirnaChehadeMD, MPHfMargaret H.CollinsMDgBrian G.FeaganMDbhiGlenn T.FurutaMDjSandeep K.GuptaMDkIkuoHiranoMDlVipulJairathMD, PhDbhiDavid A.KatzkaMDmRish K.PaiMD, PhDnMarc E.RothenbergMD, PhDoAlexStraumannMDpSeema S.AcevesMD, PhDqJeffrey A.AlexanderMDm…EkaterinaSafroneevaPhDooo

doi : 10.1016/j.jaci.2021.07.001

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Optimizing drug inhibition of IgE-mediated anaphylaxis in mice

Suzanne C.MorrisPhDaCharlesPerkinsBSbCrystalPotterBSaDavidParsonsBSaRichardSchumanPhDdMarat V.KhodounPhDaUnniSamavedamPhDaRichardStraitMDcFred D.FinkelmanMDab

doi : 10.1016/j.jaci.2021.06.022

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Mast cell surfaceome characterization reveals CD98 heavy chain is critical for optimal cell function

Siddhartha S.SahaPhDaNyssa B.SamanasPhDaIrinaMiraldaPhDaNicholas J.ShubinPhDaKerriNiinoBScaGauriBhiseBSc, MSaManasaAcharyaBScaAlbert J.SeoBScaNathanCampPhDaGail H.DeutschMDbdRichard G.JamesPhDacAdrian M.PiliponskyPhDacde

doi : 10.1016/j.jaci.2021.07.014

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Ascaris lumbricoides and ticks associated with sensitization to galactose α1,3-galactose and elicitation of the alpha-gal syndrome

TatendaMurangiBsc (Hons)aPremaPrakashPhDbBernardo PereiraMoreiraPhDbWisdomBaseraMPHcdMaresaBothaMDeStephenCunninghamPhDfHeidiFacey-ThomasDipNursCerteAliHalajianPhDgLokeshJoshiPhDfJordacheRamjithMSchFranco H.FalconePhDb∗WilliamHorsnellPhDai∗Michael E.LevinPhDe∗

doi : 10.1016/j.jaci.2021.07.018

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Novel role for caspase recruitment domain family member 14 and its genetic variant rs11652075 in skin filaggrin homeostasis

Stanley B.DeVoreMSabMariana L.StevensPhDbHuaHeMScJocelyn M.BiaginiPhDabJohn W.KronerMSbLisa J.MartinPhDacGurjit K.Khurana HersheyMD, PhDab

doi : 10.1016/j.jaci.2021.07.003

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Mast cell chymase affects the functional properties of primary human airway fibroblasts: Implications for asthma

Xinran O.ZhaoMScaMariaLampinenPhDabOlaRollmanMDbChristian P.SommerhoffPhDcAidaPaivandyPhDaGunnarPejlerPhDa

doi : 10.1016/j.jaci.2021.07.020

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Hereditary alpha tryptasemia is not associated with specific clinical phenotypes

Madeleine B.CholletMD, PhDCemAkinMD, PhD

doi : 10.1016/j.jaci.2021.06.017

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Therapeutic options for CTLA-4 insufficiency

DavidEggaIna CarolineRumpMDaNorikoMitsuikiMD, PhDaJessicaRojas-RestrepoaMaria-ElenaMaccariMDabCharlotteSchwabMDaAnnemarieGabryschMDaKlausWarnatzMDacSiguneGoldackerMDacVirginiaPatiñoMDdDanielWolffMDeSatoshiOkadaMD, PhDfSeiichiHayakawaMDfYoshiakiShikamaMDgKenjiKandaMDhKohsukeImaiMD, PhDiManabuSotomatsuMDjMakotoKuwashimaMDk…BodoGrimbacherMDacbbkkklllmmmnnn

doi : 10.1016/j.jaci.2021.04.039

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Experience with cultured thymus tissue in 105 children

M. LouiseMarkertMD, PhDabStephanie E.GuptonCPNPaElizabeth A.McCarthyRN, MSNa

doi : 10.1016/j.jaci.2021.06.028

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Genetic errors of immunity distinguish pediatric nonmalignant lymphoproliferative disorders

Lisa R.ForbesMDabcOlive S.EcksteinMDabdNityaGulatiMDabdErin C.Peckham-GregoryPhD, MPHadNmazuo W.OzuahMDabdJosephLubegaMD, MPHabdNader K.El-MallawanyMDabdJennifer E.AgrusaMDabdM. CeciliaPoliMD, PhDabeTiphanie P.VogelMD, PhDabfNatalia S.ChaimowitzMD, PhDabcNicholas L.RiderDOabcEmily M.MacePhDgJordan S.OrangeMD, PhDgJason W.CaldwellDOhJuan C.Aldave-BecerraMDiStephenJollesMD, PhDjFrancescoSaettiniMDk…Ivan K.ChinnMDabc

doi : 10.1016/j.jaci.2021.07.015

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Generation of functional human thymic cells from induced pluripotent stem cells

Stephan A.RamosBSaJohn J.MortonPhDbPrabhaYadavMBAaBrendanReedPhDacSheila I.AlizadehaAli H.ShillehMScaLoniPerrenoudBSbJamesJaggersMDfJohnKapplerPhDaeAntonioJimenoMD, PhDbdHolger A.RussPhDad∗

doi : 10.1016/j.jaci.2021.07.021

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Diagnostic merits of the Eosinophilic Esophagitis Diagnostic Panel from a single esophageal biopsy

SusieMinBAa∗TetsuoShodaMD, PhDb∗TingWenMD, PhDcMarc E.RothenbergMD, PhDab

doi : 10.1016/j.jaci.2021.07.032

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Food-dependent and food-exacerbated symptomatic dermographism: New variants of symptomatic dermographism

Muhammed BurakYücelMDaRagıpErtasMDaMuratTürkMDbMelbaMuñozMDcMustafaAtasoyMDaMarcusMaurerMDc

doi : 10.1016/j.jaci.2021.07.030

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