Crossing diagnostic boundaries to understand the genetic etiology of addiction

Travis T. Mallard 

doi : 10.1038/s41386-021-01245-6

Volume 47 Issue 10, September 2022

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Cross-ancestry genomic research: time to close the gap

Elizabeth G. Atkinson, Sevim B. Bianchi, Gordon Y. Ye, Jos?© Jaime Mart?­nez-Maga?±a, Grace E. Tietz, Janitza L. Montalvo-Ortiz, Paola Giusti-Rodrigue

doi : 10.1038/s41386-022-01365-7

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The addiction risk factor: A unitary genetic vulnerability characterizes substance use disorders and their associations with common correlates

Alexander S. Hatoum, Emma C. Johnson, Sarah M. C. Colbert, Renato Polimanti, Hang Zhou, Raymond K. Walters, Joel Gelernter, Howard J. Edenberg, Ryan B

doi : 10.1038/s41386-021-01209-w

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Sex differences in appetitive and reactive aggression

Antonio V. Aubry, C. Joseph Burnett, Nastacia L. Goodwin, Long Li, Jovana Navarrete, Yizhe Zhang, Valerie Tsai, Romain Durand-de Cuttoli, Sam A. Golde

doi : 10.1038/s41386-022-01375-5

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Prenatal opioid exposure inhibits microglial sculpting of the dopamine system selectively in adolescent male offspring

Caroline J. Smith, Tania Lintz, Madeline J. Clark, Karen E. Malacon, Alia Abiad, Nicholas J. Constantino, Veronica J. Kim, Young C. Jo, Yanaira Alonso

doi : 10.1038/s41386-022-01376-4

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Transcriptomics in the nucleus accumbens shell reveal sex- and reinforcer-specific signatures associated with morphine and sucrose craving

Hannah L. Mayberry, Charlotte C. Bavley, Reza Karbalaei, Drew R. Peterson, Angela R. Bongiovanni, Alexandra S. Ellis, Sara H. Downey, Andre B. Toussai

doi : 10.1038/s41386-022-01289-2

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Histone H3 dopaminylation in ventral tegmental area underlies heroin-induced transcriptional and behavioral plasticity in male rats

Sasha L. Fulton, Swarup Mitra, Ashley E. Lepack, Jennifer A. Martin, Andrew F. Stewart, Jacob Converse, Mason Hochstetler, David M. Dietz & Ian MazeA

doi : 10.1038/s41386-022-01279-4

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Unique and joint associations of polygenic risk for major depression and opioid use disorder with endogenous opioid system function

Tiffany Love, Andrey A. Shabalin, Rachel L. Kember, Anna R. Docherty, Hang Zhou, Vincent Koppelmans, Joel Gelernter, Anne K. Baker, Emily Hartwell, Ja

doi : 10.1038/s41386-022-01325-1

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Genome-wide meta-analysis of alcohol use disorder in East Asians

Hang Zhou, Rasmon Kalayasiri, Yan Sun, Yaira Z. Nu?±ez, Hong-Wen Deng, Xiang-Ding Chen, Amy C. Justice, Henry R. Kranzler, Suhua Chang, Lin Lu, Jie Sh

doi : 10.1038/s41386-022-01265-w

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Opioid-blunted cortisol response to stress is associated with increased negative mood and wanting of social reward

Claudia Massaccesi, Matthaeus Willeit, Boris B. Quednow, Urs M. Nater, Claus Lamm, Daniel M?¼ller & Giorgia SilaniA

doi : 10.1038/s41386-022-01283-8

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Medial orbitofrontal cortex and nucleus accumbens mediation in risk assessment behaviors in adolescents and adults

Maxine K. Loh, Nicole C. Ferrara, Jocelyn M. Torres & J. Amiel RosenkranzA

doi : 10.1038/s41386-022-01273-w

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Repeated methamphetamine administration produces cognitive deficits through augmentation of GABAergic synaptic transmission in the prefrontal cortex

Monserrat Armenta-Resendiz, Ahlem Assali, Evgeny Tsvetkov, Christopher W. Cowan & Antonieta LavinA

doi : 10.1038/s41386-022-01371-9

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mGlu1-mediated restoration of prefrontal cortex inhibitory signaling reverses social and cognitive deficits in an NMDA hypofunction model in mice

Deborah J. Luessen, Isabel M. Gallinger, Anthony S. Ferranti, Daniel J. Foster, Bruce J. Melancon, Craig W. Lindsley, Colleen M. Niswender & Jeffrey C

doi : 10.1038/s41386-022-01350-0

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Intra-individual variability and stability of affect and craving among individuals receiving medication treatment for opioid use disorder

Jennifer D. Ellis, Chung Jung Mun, David H. Epstein, Karran A. Phillips, Patrick H. Finan & Kenzie L. PrestonA

doi : 10.1038/s41386-022-01352-y

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Single doses of a highly selective inhibitor of phosphodiesterase 1 (lenrispodun) in healthy volunteers: a randomized pharmaco-fMRI clinical trial

Sahib S. Khalsa, Teresa A. Victor, Rayus Kuplicki, Hung-Wen Yeh, Kimberly E. Vanover, Martin P. Paulus & Robert E. DavisA

doi : 10.1038/s41386-022-01331-3

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Exploratory study of the dose-related safety, tolerability, and efficacy of dimethyltryptamine (DMT) in healthy volunteers and major depressive disorder

Deepak Cyril D’Souza, Shariful A. Syed, L. Taylor Flynn, Hamideh Safi-Aghdam, Nicholas V. Cozzi & Mohini RanganathanA

doi : 10.1038/s41386-022-01344-y

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In vivo correlation of serotonin transporter and 1B receptor availability in the human brain: a PET study

Jonas E. Svensson, Mikael Tiger, Pontus Plav?©n-Sigray, Christer Halldin, Martin Schain & Johan LundbergA

doi : 10.1038/s41386-022-01369-3

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IN MEMORIAM�Jan Fawcett, MD

Robert M. A. Hirschfeld 

doi : 10.1038/s41386-022-01362-w

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Correction: ACNP 60th Annual Meeting: Poster Abstracts P276 – P550

doi : 10.1038/s41386-022-01318-0

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Correction to: Intra-individual variability and stability of affect and craving among individuals receiving medication treatment for opioid use disorder

Jennifer D. Ellis, Chung Jung Mun, David H. Epstein, Karran A. Phillips, Patrick H. Finan & Kenzie L. PrestonA

doi : 10.1038/s41386-022-01372-8

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