Schwarzenberg, Sarah Jane MD *
doi : 10.1097/MPG.0000000000003669
Volume 76(2) pgs. 119-268,e21-e45 February 2023
Bosch, Barbara MD *; Holt, Peter R. MD +
doi : 10.1097/MPG.0000000000003644
AB The link between bread and wheat products and celiac disease was first recognized by Willem Dicke in the 1930s through clinical observations of his child patients. The role of gluten as the toxic factor was then proven by Drs. Dicke, Weijers and Van de Kamer in brilliant and prolonged studies in a small number of children.
Simon, David Aaron DO *; Kellermayer, Richard MD, PhD *,+
doi : 10.1097/MPG.0000000000003664
AB The microbiome is known to play an important role in the development and maintenance of human health. During early childhood the gut microbiome undergoes a rapid evolution, making this developmental window most susceptible to microbial manipulation and, therefore, most vulnerable to environmental stimuli.
Kortbeek, Simone MD *,+; Pawaria, Arti MD ++; Ng, Vicky Lee MD *,+
doi : 10.1097/MPG.0000000000003636
AB Patient-reported outcome measures (PROMs) exist for a variety of chronic gastrointestinal disorders in children. The availability of electronic (e-)formats of PROMs enhance the accessibility of these tools.
Pasternak, Brad MD *; Patel, Ashish MD *; Tran, Paul MD *; McMahon, Lisa MD *
Kellar, Amelia MD, MSc *; Dolinger, Michael MD, MBA *; Novak, Kerri L. MD, MSc +; Chavannes, Mallory MD, MHSc ++; Dubinsky, Marla MD *; Huynh, Hien MD [S]
doi : 10.1097/MPG.0000000000003649
AB Crohn disease and ulcerative colitis are chronic inflammatory bowel diseases (IBD) often diagnosed in childhood. A strict monitoring strategy can potentially alter the disease course and facilitate early effective treatment before irreversible bowel damage occurs.
Dogra, Surabhi MD *; Kumar, Karunesh MD *; Malhotra, Smita DNB *; Jerath, Nameet MD +; Sibal, Anupam MD *
doi : 10.1097/MPG.0000000000003646
The objective of the study is to estimate the incidence of acute liver failure (ALF) in dengue infection, understand the demographic and biochemical profiles, and identify prognostic factors associated with mortality.
Nayagam, Jeremy S. MD *,+; Joshi, Deepak MD, PhD *; Thompson, Richard J. MD, PhD *,+; Dhawan, Anil MD ++; Hadzic, Nedim MD ++; Mestre-Alagarda, Claudia MD *; Deheragoda, Maesha MD *; Samyn, Marianne MD ++
doi : 10.1097/MPG.0000000000003654
Elevated hepatic dry copper weight is recognized in adults with autoimmune liver disease (AILD) and chronic cholestasis. We aim to review hepatic dry copper weight in pediatric AILD.
Scarpato, Elena MD, PhD *; Salvatore, Silvia MD, PhD +; Romano, Claudio MD, PhD ++; Bruzzese, Dario MD [S]; Ferrara, Dante MD ||; Inferrera, Ramona MD ++; Zeevenhooven, Judith MD, PhD [P]; Steutel, Nina F. MD, PhD [P]; Benninga, Marc A. MD, PhD [P]; Staiano, Annamaria MD *
doi : 10.1097/MPG.0000000000003653
Reports of prevalence of functional gastrointestinal disorders (FGIDs) in infants/toddlers are widely variable. Reasons for this variability are not yet fully understood.
Coe, Alexander MD *; Ciricillo, Jacob BS +; Mansi, Sherief MD ++; El-Chammas, Khalil MD ++; Santucci, Neha MD ++; Bali, Neetu MD [S]; Lu, Peter L. MD [S]; Damrongmanee, Alisara MD ++; Fei, Lin PhD ||; Liu, Chunyan MS ||; Kaul, Ajay MD ++; Williams, Kent C. MD [S]
doi : 10.1097/MPG.0000000000003662
Chronic constipation occurs frequently in children with autism spectrum disorder (ASD). The primary objective was to determine whether chronic constipation is associated with a higher rate of abnormal colonic motor activity in ASD children than in non-ASD children.
Ma, Keon MD *; Ali, Samina MD +,++; Xie, Jianling MD, MPH [S]; Maki, Claudia MD, BN +; Lee, Bonita MD, MSc +,++; Chui, Linda PhD [P],#; Pang, Xiao-Li PhD [P],#; Zhuo, Ran PhD #; Parsons, Brendon PhD #; Vanderkooi, Otto MD **; Poonai, Naveen MD, MSc ++; MacDonald, Shannon E. PhD, RN ++++,[S][S]; Tarr, Phillip MD [//][//]; Freedman, Stephen B. MDCM, MSc [P][P]; on behalf of the Alberta Provincial Pediatric EnTeric Infection TEam (APPETITE) and Pediatric Emergency Research Canada (PERC)
doi : 10.1097/MPG.0000000000003671
Pain is common with acute gastroenteritis (AGE) yet little is known about the severity associated with specific enteropathogens. We sought to explore the correlation of pain severity with specific enteropathogens in children with AGE.
Payen, Elise MD *; Neuraz, Antoine MD, PhD +,++; Zenzeri, Letizia MD [S]; Talbotec, Cecile MD *; Abi Nader, Elie MD *; Chatenoud, Lucienne MD, PhD [//],[P]; Chhun, Stephanie MD, PhD [//],[P]; Goulet, Olivier MD, PhD *,#; Ruemmele, Frank M. MD, PhD *,#; Pigneur, Benedicte MD, PhD *,**
doi : 10.1097/MPG.0000000000003643
European Crohn's Colitis Organization (ECCO) and the European Society of Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) guidelines recommend the early use of anti-tumor necrosis factor (TNF) biologicals in pediatric Crohn disease (CD) patients with positive predictors for poor outcome.
Broekaert, Ilse J. *; Klein, Ariane *,+; Windschall, Daniel ++,[S]; Rogalski, Betina [//]; Weller-Heinemann, Frank [P]; Oommen, Prasad #; Kuster, Michael **; Foeldvari, Ivan ++; Minden, Kirsten ++++; Hospach, Anton [S][S]; Hufnagel, Markus [//][//]; Berger, Thomas [P][P]; Geikowski, Til ##; Quietzsch, Jurgen ***; Horneff, Gerd *,+
doi : 10.1097/MPG.0000000000003656
The aim of our study was to describe the distinct features of inflammatory bowel disease (IBD) in juvenile idiopathic arthritis (JIA) patients and to identify risk factors for its development.
Bronsky, Jiri MD, PhD *; Copova, Ivana MD *; Durilova, Marianna MD, PhD *; Kazeka, Denis MD *; Kubat, Michal MD *; Lerchova, Tereza MD, PhD *; Vlckova, Eva MD *; Mitrova, Katarina MD, PhD *,+; Rataj, Michal ++; Klocperk, Adam MD, PhD ++; Sediva, Anna MD, PhD ++; Hradsky, Ondrej MD, PhD *
doi : 10.1097/MPG.0000000000003661
AB Objectives: We prospectively compared the postvaccination immunity to messenger ribonucleic acid BNT162b2 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine of our pediatric patients over 12 years old with inflammatory bowel disease (IBD) to that of healthy controls and looked for predictors of its robustness.
Salguero, Maria V. MD, MSc *; Deplewski, Dianne MD *; Gokhale, Ranjana MD +; Wroblewski, Kristen MS ++; Sentongo, Timothy MD +; Jan, Aseel B.S.Micr +; Kirschner, Barbara S. MD +
doi : 10.1097/MPG.0000000000003667
Growth impairment in pediatric patients with pediatric onset inflammatory bowel disease (IBD) is multifactorial. Reports on the effect of age at menarche on adult stature in this population are limited.
Gutierrez-Junquera, Carolina MD, PhD *; Fernandez-Fernandez, Sonia MD, PhD +; Dominguez-Ortega, Gloria MD, PhD ++; Vila Miravet, Victor MD [S]; Garcia-Puig, Roger MD ||; La Orden-Izquierdo, Enrique MD, PhD [P]; Pena Quintana, Luis MD, PhD #; Barrio Torres, Josefa **; Medina Benitez, Enrique MD ++; Leis, Rosaura MD, PhD ++++; Garcia-Romero, Ruth MD, PhD [S][S]; Fernandez de Valderrama, Ana MD, PhD ||||; Vecino Lopez, Raquel MD, PhD [P][P]; Donado Palencia, Paloma MD ##; on behalf of the SEGHNP EoE Working Group; Beltran, Marina Alvarez; Reyes-Dominguez, Ana Isabel; Colome-Rivero, Gemma; Manchon, Silvia Rodriguez; Martinon, Nazareth; Fernandez-Caamano, Beatriz; Garrido, Helena Lorenzo; Comas, Amadeu Roca; Riechmann, Enriqueta Roman; Pascual, Maria Luz Cilleruelo; Telleria, Pedro Urruzuno; Arocena, Francisco Javier Eizaguirre; Serrano, Elena Balmaseda; Garcia, Patricia Barros; Arnal, Ignacio Ros; Garcia, Gloria Rodrigo; Diaz, Anabel Ruiz; Poblet, Gonzalo Galicia; de la Barreda, Laura; Querol, Montserrat Montraveta; Vicente, Carmen Alonso; Santamaria, Saioa Vicente; Jaime, Beatriz Espin; Peral, Ricardo Torres; Peris, Monica Garcia; Vegas Alvarez, Ana Maria; Blazquez, Cristina Iglesias
doi : 10.1097/MPG.0000000000003660
To assess the short- and long-term efficacy of proton pump inhibitor (PPI) therapy for pediatric eosinophilic esophagitis (EoE) in real-world practice with a step-down strategy, and to evaluate factors predictive of PPI responsiveness.
Nasr, Alexander MD *; Hornung, Lindsey MS +; Thompson, Tyler BA *; Lin, Tom K. MD *,++; Vitale, David S. MD *,++; Nathan, Jaimie D. MD [S]; Varni, James W. PhD ||; Abu-El-Haija, Maisam MD, MS *,++
doi : 10.1097/MPG.0000000000003668
This study aims to describe the prevalence of gastrointestinal (GI) symptoms following the first time occurrence of acute pancreatitis (AP) and to measure the impact of the episode on patient health-related quality of life (HRQOL) from the perspectives of patients and parents.
Holzapfel, Lindsay F. MD, MS *,+; Hair, Amy B. MD +; Preidis, Geoffrey A. MD, PhD ++; Halder, Tripti BS, BED ++; Yang, Heeju BS +; Unger, Jana P. RD, LD, MS +,[S]; Freedman, Steven MD, PhD ||,[P]; Martin, Camilia R. MD, MS #
doi : 10.1097/MPG.0000000000003672
Preterm infants are born functionally pancreatic insufficient with decreased pancreatic production of lipase and proteases. Developmental pancreatic insufficiency (PI) may contribute to reduced nutrient absorption and growth failure. We sought to determine longitudinal fecal elastase (ELA1) levels in a cohort of preterm infants and whether levels are associated with growth outcomes.
Quitadamo, Paolo MD *; Battagliere, Ilaria MD +; Del Bene, Margherita MD +; Caruso, Flora MD *; Gragnaniello, Piergiorgio MD +; Dolce, Pasquale PhD ++; Caldore, Mariano MD *; Bucci, Cristina MD *
doi : 10.1097/MPG.0000000000003655
To assess the clinical complications reported after the ingestion of sharp/pointed foreign bodies (FBs) in pediatric age, their incidence among all FB ingestions, and the features and clinical presentation of children.
Saros, Lotta MSc *; Vahlberg, Tero MSc +; Koivuniemi, Ella MSc *; Houttu, Noora MSc *; Niinikoski, Harri MD, PhD *,++; Tertti, Kristiina MD, PhD [S]; Laitinen, Kirsi PhD *,||
doi : 10.1097/MPG.0000000000003659
To evaluate whether a fish oil and/or probiotics intervention in pregnant women with overweight or obesity would influence the tendency of their 24-month-old children to become overweight and alter their body fat percentage.
Jankiewicz, Mateusz MD *; Lukasik, Jan MD, PhD *; Kotowska, Maja MD *; Kolodziej, Maciej MD, PhD *; Szajewska, Hania MD, PhD *
doi : 10.1097/MPG.0000000000003675
The dogma of probiotic strain-specificity is widely accepted. However, only the genus- and species-specific effects of probiotics are supported by evidence from clinical trials.
Szajewska, Hania MD *; Berni Canani, Roberto MD +; Domellof, Magnus MD ++; Guarino, Alfredo MD +; Hojsak, Iva MD [S]; Indrio, Flavia MD ||; Lo Vecchio, Andrea MD +; Mihatsch, Walter A. MD [P]; Mosca, Alexis MD #; Orel, Rok MD **; Salvatore, Silvia MD ++; Shamir, Raanan MD ++++; van den Akker, Chris H. P. MD [S][S]; van Goudoever, Johannes B. MD [S][S]; Vandenplas, Yvan MD ||||; Weizman, Zvi MD [P][P]; on behalf of the ESPGHAN Special Interest Group on Gut Microbiota and Modifications; Canani, R. Berni; Guarino, A.; Dinleyci, E. C.; Domellof, M.; Indrio, F.; Hojsak, I.; Gutiierez, P.; Kolacek, S.; Mihatsch, W. A.; Mosca, A.; Orel, R.; Salvatore, S.; Shamir, R.; Szajewska, H.; Vandenplas, Y.; van den Akker, C. H. P.; van Goudoever, J. B.; Weizman, Z.
doi : 10.1097/MPG.0000000000003633
Probiotics, defined as live microorganisms that, when administered in adequate amounts, confer a health benefit on the host, are widely used despite uncertainty regarding their efficacy and discordant recommendations about their use.
Embleton, Nicholas David MBBS, BSc, MD *; Jennifer Moltu, Sissel MD, PhD +; Lapillonne, Alexandre MD, PhD ++[S]; van den Akker, Chris H.P. MD, PhD ||; Carnielli, Virgilio MD, PhD [P]; Fusch, Christoph MD, PhD #,**; Gerasimidis, Konstantinos PhD ++; van Goudoever, Johannes B. MD, PhD ++++; Haiden, Nadja MD, MSc [S][S]; Iacobelli, Silvia MD, PhD ||||; Johnson, Mark J. BM, BSc, PhD [P][P],##; Meyer, Sascha MD, PhD ***; Mihatsch, Walter MD, MBA +++,++++++; de Pipaon, Miguel Saenz MD, PhD [S][S][S]; Rigo, Jacques MD, PhD ||||||; Zachariassen, Gitte MD, PhD [P][P][P]; Bronsky, Jiri MD, PhD ###; Indrio, Flavia MD, PhD ****; Koglmeier, Jutta MD, PhD ++++; de Koning, Barbara MD, PhD ++++++++; Norsa, Lorenzo MD, PhD [S][S][S][S]; Verduci, Elvira MD, PhD ||||||||,[P][P][P][P]; Domellof, Magnus MD, PhD ####
doi : 10.1097/MPG.0000000000003642
To review the current literature and develop consensus conclusions and recommendations on nutrient intakes and nutritional practice in preterm infants with birthweight <1800 g.
Oduru, Olawale MD *; Jo Gumm, Alexis MD +; Sigurdsson, Luther MD ++; Cook, Shelley MD [S]; O'Connell, Daniel M. MD ++
Banaszkiewicz, Aleksandra MD, PhD *; Bukowski, Jan MD *; Pertkiewicz, Jan MD, PhD +; Dembinski, Lukasz MD, PhD *; Kluczewska, Ewa MD, PhD ++; Kwiecien, Jaroslaw MD, PhD [S]
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