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46th Annual Meeting The American Society of Pediatric Neurosurgeons
doi : 10.3171/2023.3.PEDS.ASPN2023Abstracts
Volume 31: Issue 3 (Mar 2023)
Editorial. The elusive fibrofatty filum holy grail
Jeffrey P. Blount MD, MPH and Michael D. Partington MD, MS
Fibrofatty filum terminale: long-term outcomes from a Singapore children’s hospital
Jia Xu Lim  MBBS , Elizabeth Fong  MBBS , Cheryl Goh  MBBS , Lee Ping Ng  BNS , Khurshid Merchant  MBBS , David C. Y. Low  MBBS , Wan Tew Seow  MBBS , and Sharon Y. Y. Low  MBBS, PhD
doi : 10.3171/2022.8.PEDS22103
The role of prophylactic detethering a fibrofatty filum terminale (FFT) remains equivocal. Furthermore, long-term studies focusing on urological outcomes are sparse. The aims of this study were to present an institutional experience on the perioperative and long-term outcomes of FFT surgery and to assess for factors that contribute to postoperative clean intermittent catheterization (CIC).
Stereoelectroencephalography followed by combined electrode removal and MRI-guided laser interstitial thermal therapy or open resection: a single-center series in pediatric patients with medically refractory epilepsy
Anna L. Slingerland BS , Melissa M. J. Chua MD , Jeffrey Bolton MD , Steven J. Staffa MS , Melissa Tsuboyama MD , Sanjay P. Prabhu MBBS , Phillip L. Pearl MD , Joseph R. Madsen MD , and Scellig S. D. Stone MD, PhD
doi : 10.3171/2022.11.PEDS22262
Stereoelectroencephalography (SEEG) and MRI-guided laser interstitial thermal therapy (MRgLITT) have emerged as safe, effective, and less invasive alternatives to subdural grid placement and open resection, respectively, for the localization and treatment of medically refractory epilepsy (MRE) in children.
Germline genetic mutations in pediatric cerebrovascular anomalies: a multidisciplinary approach to screening, testing, and management
Melissa A. LoPresti MD, MPH , Rebecca Y. Du MD , Jae Eun Lee BA , Ionela Iacobas MD , Katie Bergstrom MS, CGC , Samuel G. McClugage III MD , and Sandi K. Lam MD, MBA
doi : 10.3171/2022.11.PEDS22392
Genetic alterations are increasingly recognized as etiologic factors linked to the pathogenesis and development of cerebrovascular anomalies. Their identification allows for advanced screening and targeted therapeutic approaches.
Head and neck angiography in the pediatric population: single-center experience with indications, safety, feasibility, and technical differences among infants, childhood, and adolescents
Andre Monteiro MD , Brianna M. Donnelly BS , Matthew J. Recker MD , Asham Khan MD , Jason M. Davies MD, PhD , Kenneth V. Snyder MD, PhD , Renee M. Reynolds MD , Adnan H. Siddiqui MD, PhD , and Elad I. Levy MD, MBA
doi : 10.3171/2022.11.PEDS22385
Pediatric patients are candidates for head and neck endovascular procedures less frequently than adults. Data on utilization, feasibility, safety, and technical details of head and neck angiography in the pediatric population are scarce.
Increasing precision in the management of pediatric neurosurgical cerebrovascular diseases with molecular genetics
Kristopher T. Kahle MD, PhD , Daniel Duran MD , and Edward R. Smith MD
doi : 10.3171/2022.12.PEDS22332
Recent next-generation DNA and RNA sequencing studies of congenital and pediatric cerebrovascular anomalies such as moyamoya disease, arteriovenous malformations, vein of Galen malformations, and cavernous malformations have shed new insight into the genetic regulation of human cerebrovascular development by implicating multiple novel disease genes and signaling pathways in the pathogenesis of these disorders.
Ventriculosinus shunts: their role in selected patients
Segev Gabay MD , Dymtro Zhebrykov MD , Shlomi Constantini MD, MSc , and Jonathan Roth MD
doi : 10.3171/2022.11.PEDS22406
Ventriculoperitoneal shunt placement is the most common treatment for hydrocephalus. However, most patients will require multiple shunt revisions over time.
Impact of intraventricular hemorrhage symmetry on endoscopic third ventriculostomy with choroid plexus cauterization for posthemorrhagic hydrocephalus: an institutional experience of 50 cases
Victor M. Lu MD, PhD , Shelly Wang MD, MPH , Toba N. Niazi MD , and John Ragheb MD
doi : 10.3171/2022.12.PEDS22492
The success rate of endoscopic third ventriculostomy with choroid plexus cauterization (ETV/CPC) in the management of posthemorrhagic hydrocephalus (PHH) following intraventricular hemorrhage (IVH) in infants is not well defined. Furthermore, parameters of IVH at initial presentation have not been tested for predictive associations of ETV/CPC success in this setting.
Effect of clevidipine on intracranial pressure in pediatric neurosurgical patients: a single-center retrospective review
Elizabeth Vadasz PharmD , Jeffrey Moss PharmD , Nathan Chang MSN , May Casazza MSN , and Lindsey Rasmussen MD
doi : 10.3171/2022.11.PEDS22255
Hemodynamic management in pediatric neurosurgical patients is essential for maintaining cerebral perfusion pressure (CPP), avoiding hemorrhage, and preventing secondary neurological injury.
Surveillance imaging and early surgical intervention for improved CNS tumor outcomes in children with Li-Fraumeni syndrome: Children's National Hospital experience and literature review
Nirali Patel MD , Kathleen Felton MD , Surajit Bhattacharya PhD , Maria Isabel Almira-Suarez MD , Augustine Eze MS , Joyce Turner MS , Robert Keating MD , Chima Oluigbo MD , Reuven J. Schore MD , Lindsay Kilburn MD , Roger J. Packer MD , John S. Myseros MD , and Miriam Bornhorst MD
doi : 10.3171/2022.12.PEDS22261
Li-Fraumeni syndrome (LFS) is a cancer predisposition syndrome caused by germline mutations in the TP53 gene. CNS tumors are the fourth most common tumor type in LFS, and recent screening guidelines demonstrate that early tumor detection is associated with improved long-term survival.
Local conceptions of the role of folate in neural tube defects in Zambia
Jeffrey W. Chen BA , Nathan A. Shlobin BA , Arnold Bhebhe MD , Shilin Zhao PhD , Chevis N. Shannon DrPH, MBA, MPH , Kachinga Sichizya MD , Christopher M. Bonfield MD , and Rebecca A. Reynolds MD
doi : 10.3171/2022.11.PEDS22217
In sub-Saharan Africa, neural tube defects (NTDs) are the second most common birth defect, occurring eight times more frequently than in the US. The objective of this study was to assess baseline Zambian caregiver understanding of folate and NTDs and the effectiveness of an NTD prevention educational program.
