Riccardo Balestri, Michela Magnano, Giulia Rech
doi : 10.1111/jdv.18950
Florian Rieder, Pranab K. Mukherjee
doi : 10.1111/jdv.18991
Alain Taieb
doi : 10.1111/jdv.18971
Nicolas Kluger, Pierre Vabres
doi : 10.1111/jdv.18833
Lloyd Steele, Xiang Li Tan, Bayanne Olabi, Jing Mia Gao, Reiko J. Tanaka, Hywel C. Williams
doi : 10.1111/jdv.18814
Machine learning (ML) models for skin cancer recognition may have variable performance across different skin phototypes and skin cancer types. Overall performance metrics alone are insufficient to detect poor subgroup performance. We aimed (1) to assess whether studies of ML models reported results separately for different skin phototypes and rarer skin cancers, and (2) to graphically represent the skin cancer training datasets used by current ML models.
Aditya K. Gupta, Tong Wang, Shruthi Polla Ravi, Mary A. Bamimore, Vincent Piguet, Antonella Tosti
doi : 10.1111/jdv.18810
Management options for moderate-to-severe alopecia areata (AA) are limited owing to a lack of safe and effective treatments suitable for long-term use. However, newer agents have the potential to induce and maintain hair regrowth in patients with a better side-effects profile compared to systemic steroids or conventional systemic agents.
Pietro Quaglino, Julia Scarisbrick, Gabriele Roccuzzo, Alejandra Abeldano, Maxime Battistella, Chris McCormack, Richard Cowan, Antonio Cozzio, Jade Cury-Martins, Paula Enz, Larisa Geskin, Emmanuella Guenova, Youn H. Kim, Robert Knobler, Ivan V. Litvinov, Tomomitsu Miyagaki, Montserrat Molgo, Jan Nicolay, Evangelina Papadavid, Lauren Pinter-Brown, Ramon Pujol Vallverdu, Christiane Querfeld, Pablo Ortiz-Romero, Rudolf Stadler, Maarten H. Vermeer, Martine Bagot, Emmilia Hodak
doi : 10.1111/jdv.18852
Consensus about the definition and classification of ‘plaque’ in mycosis fungoides is lacking.
Natalia Rompoti, Maria Politou, Irene Stefanaki, Charitomeni Vavouli, Marina Papoutsaki, Afroditi Neofotistou, Dimitrios Rigopoulos, Alexander Stratigos, Electra Nicolaidou
doi : 10.1111/jdv.18825
Brodalumab, a fully human IgG2k antibody blocking the receptor of IL17, is characterized by a rapid onset of action with high skin clearance rates in clinical trials. Since setting PASI90/100 or absolute PASI ≤ 3 as treatment goals have become attainable, evaluating the effectiveness and safety profile of biologic agents, such as brodalumab, in a real-world setting is essential.
Lisa Schots, Rani Soenen, Brigitte Blanquart, Debby Thomas, Jo Lambert
doi : 10.1111/jdv.18827
Real-world studies on the use of biologics in psoriasis (Pso) are increasing, but still scarce. Trough concentrations (Cts) of interleukin-17 inhibitors (IL-17i) seem promising for clinical decision-making, but their value in daily practice has yet to be proven.
Richard B. Warren, Bruce Strober, Jonathan I. Silverberg, Emma Guttman, Philippe Andres, Jakob Felding, Deniz Tutkunkardas, Kim Kjøller, Morten O. A. Sommer, Lars E. French
doi : 10.1111/jdv.18812
Orismilast is a high-potency phosphodiesterase 4 (PDE4) inhibitor with enhanced selectivity for the PDE4B and PDE4D subtypes.
Jonathan I. Silverberg, Lars E. French, Richard B. Warren, Bruce Strober, Kim Kjøller, Morten O. A. Sommer, Philippe Andres, Jakob Felding, Anne Weiss, Deniz Tutkunkardas, Tine Skak-Nielsen, Emma Guttman
doi : 10.1111/jdv.18818
There remains an unmet need for oral medications that are safe and efficacious for long-term management of chronic inflammatory skin diseases (CISD). Inhibition of phosphodiesterase 4 (PDE4) can modulate a broad range of pro-inflammatory cytokines that play a major role in CISD pathogenesis. Orismilast is a second generation PDE4 inhibitor in clinical development for CISD treatment.
Alexander A. Navarini, Jörg C. Prinz, Akimichi Morita, Tsen-Fang Tsai, Manuelle-Anne Viguier, Ling Li, Christian Thoma, Mogana Sivalingam, Mark G. Lebwohl
doi : 10.1111/jdv.18820
Generalized pustular psoriasis (GPP) is a rare inflammatory skin disease with a considerable clinical burden. In the Effisayilâ„¢ 1 study, spesolimab, an anti-interleukin-36 receptor monoclonal antibody, demonstrated efficacy in treating GPP flares.
LluÃs Puig, Siew Eng Choon, Alice B. Gottlieb, Slaheddine Marrakchi, Jörg C. Prinz, Ricardo Romiti, Yayoi Tada, Dorothea von Bredow, Melinda Gooderham
doi : 10.1111/jdv.18851
Generalized pustular psoriasis (GPP) is a rare and highly heterogeneous skin disease, characterized by flares of neutrophilic pustules and erythema. As a rare disease with few clinical studies and no standardized management approaches, there is a paucity of knowledge regarding GPP.
Khalaf Kridin, Marie-Charlotte Brüggen, Sarah Walsh, Benoit Bensaid, Annamari Ranki, Eva Oppel, Damian Meyersburg, Ser-Ling Chua, Corsin Seeli, Heidi Sandberg, Lars E. French, Artem Vorobyev, Saskia Ingen-Housz-Oro
doi : 10.1111/jdv.18808
Drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare but potentially fatal drug hypersensitivity reaction.
Stephanie M. Rangel, Theodore Kim, Anjani Sheth, Alli Blumstein, Jin-Shei Lai, David Cella, Amy S. Paller, Jonathan I. Silverberg
doi : 10.1111/jdv.18819
Fatigue is a symptom that can negatively impact patients' quality of life. However, the relationship of AD with fatigue has not been fully studied, especially in children.
Luise Rauer, Matthias Reiger, Madhumita Bhattacharyya, Patrick M. Brunner, James G. Krueger, Emma Guttman-Yassky, Claudia Traidl-Hoffmann, Avidan U. Neumann
doi : 10.1111/jdv.18776
Atopic dermatitis (AD) is a heterogeneous, chronic inflammatory skin disease linked to skin microbiome dysbiosis with reduced bacterial diversity and elevated relative abundance of Staphylococcus aureus (S. aureus).
Bertrand Nyuykonge, Emmanuel Siddig, Najwa A. Mhmoud, Sahar Bakhiet, Eduard Zijlstra, Annelies Verbon, Ahmed H. Fahal, Wendy W. J. van de Sande
doi : 10.1111/jdv.18642
Eumycetoma is a neglected tropical infection of the subcutaneous tissue commonly caused by the fungus Madurella mycetomatis. Previously, we demonstrated that β-D-glucan was present in the serum of eumycetoma patients.
Kamila Jaworecka, Dominika Kwiatkowska, Luiza Marek-Józefowicz, Funda Tamer, Aleksandra Stefaniak, Magdalena Szczegielniak, Joanna Chojnacka-Purpurowicz, Ayla Gulekon, Jacek C. Szepietowski, Joanna Narbutt, Agnieszka Owczarczyk-Saczonek, Adam Reich
doi : 10.1111/jdv.18850
Pruritus, which is the most frequent subjective symptom of psoriasis, may cause significant discomfort, embarrassment and even interfere with patients normal daily activities. However, the perception of itch in various psoriasis subtypes remains unknown.
Lei Zhou, Han Zhao, He Zhao, Xin Meng, Zhixiang Zhao, Hongfu Xie, Ji Li, Yan Tang, Yiya Zhang
doi : 10.1111/jdv.18725
Rosacea is a chronic inflammatory skin disease with increased macrophage infiltration. However, the molecular mechanism remains unclear.
Christos C. Zouboulis, Katarzyna P. Kaleta, Elżbieta Broniatowska, Vaiva JarienÄ—, Georgios Nikolakis
doi : 10.1111/jdv.18844
Atrophic papulosis (Köhlmeier–Degos disease, Degos disease) is a rare thrombo-obliterative microangiopathy of unknown pathogenesis. It usually affects people between the ages of 20 and 50. However, it can occur at any age. The condition is considered uncommon in children.
Leonie Frommherz, Katalin Komlosi, Charlotte Hewel, Julia Kopp, Malin Dewenter, Andreas Zimmer, Oliver Bartsch, Matthias Linke, Kristin Technau-Hafsi, Susanne Gerber, Judith Fischer, Cristina Has
doi : 10.1111/jdv.18719
Most cases of hereditary ichthyoses present with generalized scaling and skin dryness. However, in some cases skin involvement is restricted to particular body regions as in acral lamellar ichthyosis.
Rolf-Markus Szeimies, Christoph Abels, Ana Kilic, Hubert Reich, Birgit Berger, Erik Schulze zur Wiesche, Katharina Schramm, Leonie Litzka, Susanne Heimstaedt-Muskett, Clarissa Masur
doi : 10.1111/jdv.18843
Primary axillary hyperhidrosis (PAHH) strongly affects the patient's quality of life. To date, topical treatment options are limited. One percent glycopyrronium bromide (GPB) showed promising efficacy and safety in a pivotal 4-week Phase 3a study.
Johannes Ring
doi : 10.1111/jdv.18972
Man Man Niu, Qi Jiang, Yue Cao, Qian Yang, Yan Fang Zhang, Dao Ting Li, Peng Hu
doi : 10.1111/jdv.18784
Giuseppe Stinco, Enzo Errichetti, Matteo Figini, Alba Guglielmo, Benedetta Fazzi, Luca Quartuccio, Alen Zabotti, Salvatore De Vita, Miriam Isola, Maria De Martino, Silvia Rossi, Riccardo Lucis, Martina Fabris, Antonio Paolo Beltrami, Francesco Curcio, Federica D'Aurizio
doi : 10.1111/jdv.18809
Iria Neri, Alba Guglielmo, Annalucia Virdi, Miriam Leuzzi, Bianca Maria Piraccini, Marco Adriano Chessa
doi : 10.1111/jdv.18815
Gianluca Avallone, Carlo Alberto Maronese, Claudio Conforti, Paolo Fava, Luigi Gargiulo, Angelo Valerio Marzano, Cesare Massone, Luca Mastorino, Andrea Paradisi, Alessandro Pileri, Pietro Quaglino, Nathalie Rizzo, Simone Ribero, Gabriele Roccuzzo, Gianluca Tavoletti, Carlo Alberto Vignoli, Iris Zalaudek, Emilio Berti, Silvia Alberti-Violetti
doi : 10.1111/jdv.18806
Btisseme Ahouach, Emmanuelle Diaz, Blandine Bertin, Benoit Ben Said, Sandrine Combret, Aurélie Grandvuillemin, Nadine Petitpain, Marie Blanche Rabier, Laure Thomas, Thierry Trenque, Saskia Ingen-Housz-Oro, Bénédicte Lebrun-Vignes
doi : 10.1111/jdv.18845
Nicoline F. Post, Vidhya S. Narayan, Marcel W. Bekkenk, Albert Wolkerstorfer
doi : 10.1111/jdv.18829
Margaux Mongereau, Camille Hua, Tomas Urbina, Paul Louis Woerther, Tiphaine Pelegrin, Nicola de'Angelis, Quentin De Roux, Romain Bosc, Barbara Hersant, Nicolas de Prost, Olivier Chosidow
doi : 10.1111/jdv.18729
Inês AparÃcio Martins, Clara Valente, Pedro Simões Farinha, Beatriz Figueira Vilela, Joana Cabete
doi : 10.1111/jdv.18702
Neslihan Demirel Öğüt
doi : 10.1111/jdv.18601
Miriam Fernández-Parrado, Héctor Perandones-González
doi : 10.1111/jdv.18525
Thilo Gambichler, Martin Doerler, Christina H. Scheel, Klara Bastek, Maria Chatzipantazi
doi : 10.1111/jdv.18607
Javier Cañueto, Luis Antonio Corchete-Sánchez, Chrysalyne D. Schmults, Natalia GarcÃÂa-Sancha, Roberto Corchado-Cobos, Marina Mendiburu-Eliçabe, ÃÂ�ngel Santos-Briz, Esther Cardeñoso-ÃÂ�lvarez, Jesús Pérez-Losada, Concepción Román-Curto, Emily S. Ruiz
doi : 10.1111/jdv.18775
Christina Mitteldorf, Norman Langer, Werner Kempf, Michael P. Schön
doi : 10.1111/jdv.18741
Emily A. Cowen, Mary Daotung Sun, Lilly Gu, Christian Acevedo, Veronica Rotemberg, Allan C. Halpern
doi : 10.1111/jdv.18671
Julia M. K. Clabbers, Marieke C. Bolling, Charlotte Burms, Maaike Vreeburg, Henny H. Lemmink, Peter C. van den Akker, Peter M. Steijlen, Michel van Geel, Antoni H. Gostyński
doi : 10.1111/jdv.18699
Pavel V. Chernyshov, Lucia Tomas-Aragones, Dennis Linder, Anthony Bewley, Carmen Maria Salavastru, Servando E. Marron, Liana Manolache, Nives Pustisek, Andrea W. M. Evers, Dimitra Koumaki, Damiano Abeni, Alina Suru, Sam S. Salek, Andrew Y. Finlay
doi : 10.1111/jdv.18687
Clara Valente, Bruno Duarte
doi : 10.1111/jdv.18714
Pedro Redondo, Jesús Barrio, Rafael Salido-Vallejo, Alejandra Tomás-Velázquez
doi : 10.1111/jdv.18712
Michela Starace, Aurora Maria Alessandrini, Val Constantine S. Cua, Federico Francesco Cucinotta, Francesca Bruni, Matilde Iorizzo, Bianca Maria Piraccini
doi : 10.1111/jdv.18748
Diamant Thaçi, Stefano Piaserico, Kristian Gaarn Du Jardin, Richard B. Warren
doi : 10.1111/jdv.18783
Elisa Joly, Anissa Desmoulin, Phuong-Lien Tran, Christian Derancourt, Antoine Bertolotti
doi : 10.1111/jdv.18828
Takuya Kawamura, Ken Muramatsu, Akihiro Orita, Yosuke Mai, Tatsuro Sugai, Naoya Haga, Yu Fujimura, Toshinari Miyauchi, Kentaro Izumi, Hiroshi Koga, Norito Ishii, Hideyuki Ujiie
doi : 10.1111/jdv.18704
Adam Reich, Jacek C. Szepietowski, Sophie Baradat, Marie Dominique Thouvenin, Fabienne Carballido
doi : 10.1111/jdv.18740
Tyng-Shiuan Hsieh, Tom C. Chan, Yung-Tsu Cho, Chia-Yu Chu
doi : 10.1111/jdv.18734
Francisco Javier Melgosa Ramos, Ramón GarcÃÂa Ruiz, Andrea Estébanez Corrales, Almudena Mateu Puchades
doi : 10.1111/jdv.18685
Leila Asfour, Leslie N. Jones, Rodney D. Sinclair
doi : 10.1111/jdv.18754
Joanna Maj, Kamila Wala, Jacek C. Szepietowski
doi : 10.1111/jdv.18621
Na Young Kim, Dong-Uk Cheon, Hae Chang Joh, Jeong Eun Kim
doi : 10.1111/jdv.18682
Amaani B. Hussain, Alison Havelin, Stephanie Ball, Sophie Weatherhead, Nick J. Reynolds, Philip Hampton
doi : 10.1111/jdv.18623
Takashi Hashimoto, Manami Okuzawa, Satoshi Okuno, Takahiro Satoh
doi : 10.1111/jdv.18823
Pavel V. Chernyshov, Kamila Wala, Ewa Wójcik, Jacek С. Szepietowski
doi : 10.1111/jdv.18744
Katharina Boch, Henner Zirpel, Diamant Thaci, Noor Mruwat, Detlef Zillikens, Ralf J. Ludwig, Khalaf Kridin
doi : 10.1111/jdv.18700
Angèle Soria, Emmanuelle Amsler, Bethsabée Garel, Philippe Moguelet, Nathalie Tieulié, Florence Cordoliani, Isabelle Guichard, Antoine Mahé, Gilles Grateau, Guilaine Boursier, Sophie Georgin-Lavialle
doi : 10.1111/jdv.18771
Ida Vittrup, Jesper Elberling, Lone Skov, Kristina Sophie Ibler, Gregor B. E. Jemec, Charlotte G. Mortz, Rasmus Overgaard Bach, Carsten Bindslev-Jensen, Maiken Glud Dalager, Alexander Egeberg, Maria Kamstrup, Mette Deleuran, Christian Vestergaard, Jacob P. Thyssen
doi : 10.1111/jdv.18804
Giulia Bazzacco, Enrico Zelin, Ludovica Toffoli, Claudio Conforti, Nicola di Meo, Dahlia Fedele, Iris Zalaudek
doi : 10.1111/jdv.18705
Chloé David-Ferreira, Estelle Ravni, Céline Bourgea, Elisa Cinotti, Linda Tognetti, Jean-Luc Perrot, François Skowron
doi : 10.1111/jdv.18821
Gianluca Avallone, Carlo Alberto Maronese, Eleonora Quattri, Gabriele Roccuzzo, Luca Mastorino, Silvia Alberti-Violetti, Stefano Ramoni, Anna Lucchini, Sergio Delmonte, Pietro Quaglino, Angelo Valerio Marzano, Simone Ribero
doi : 10.1111/jdv.18695
Caroline Meyer Olesen, Yasemin Topal Yüksel, Claus Zachariae, Tamara Theresia Lund, Tove Agner, Tonny Studsgaard Petersen, Jacob Pontoppidan Thyssen
doi : 10.1111/jdv.18805
Francisco J. RodrÃguez-Cuadrado, Marta Elosua-González, Gaston Roustan-Gullón, Fernando Alfageme-Roldán
doi : 10.1111/jdv.18650
Mathieu Daoud, Farida Benhadou, Hassane Njimi, Gregor B. E. Jemec, Mathilde Daxhelet, Jonathan White, Stéphanie Heudens, Jalila Karama, Mariano Suppa, Veronique del Marmol
doi : 10.1111/jdv.18707
Tae Hyung Kim, Hyoungsoo Park, Du Jin Baek, Hee Young Kang
doi : 10.1111/jdv.18757
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