Shanshan Yu, Maowen Yu, Jianjun Chen, Hongbo Tang, Wuqing Gong, Hui Tan
doi : 10.1111/aji.13651
Ovarian cancer (OC) is a common gynecologic cancer with high incidence and mortality. We attempted to investigate the role of circular RNA_0000471 (circ_0000471) in OC progression and its associated mechanism.
Jing Peng, Huixi Li, Shaojun Yang, Xuyuan Zhang, Patrick Z. Li, Xiaohua Nie, Liguo Zhang, Zhichao Zhang
doi : 10.1111/aji.13678
Draining lymph nodes (LNs) are pivotal sites for maintaining tolerance to self-antigens as well as eliciting immune responses to exogenous antigens. The epididymis is a male reproductive organ with a unique local immune environment.
Anna Maya Powell, Deborah Persaud, Jean Rene Anderson, Deborah Kacanek, Yanling Huo, Kevin Psoter, Lisa R. Yanek, Khalil Ghanem, Irina Burd, the International Maternal Pediatric Adolescent AIDS Clinical Trial (IMPAACT) 1025 protocol team
doi : 10.1111/aji.13680
Maternal markers of intestinal immune activation may be used to predict preterm birth (PTB) in pregnant women living with HIV.
Wenzhe Zhang, Shiru Xu, Rongrong Zhang, Zhuqing Li, Nianyu Li, Xiruo Zhang, Yueshuang Lu, Yuehong Bian, Ping Yang, Fang Fang, Yingying Qin, Xue Jiao
doi : 10.1111/aji.13685
Is deficiency of IL-22 associated with premature ovarian insufficiency (POI)?
Ling Shuai, Jiajie She, Ruiying Diao, Huihui Zhao, Xuemin Liu, Qingyu Hu, Dongdong Li, Danna Su, Xiaofeng Ye, Yan Guo, Mei Zhong, Liping Wang
doi : 10.1111/aji.13686
The role of hydroxychloroquine (HCQ) in premature ovarian insufficiency (POI) remains unclear. The purpose of this study was to evaluate the effect of HCQ on ovarian function in mice with POI and to clarify its potential mechanisms.
Viviana Arroyo-Jousse, Arturo Borzutzky, MarÃÂa Rosa Bono, Paola Casanello
doi : 10.1111/aji.13687
Maternal obesity (MO) is associated with a higher risk of immune-mediated diseases in the offspring and higher leptin levels in cord blood (CB). This study evaluates the number and function of lymphocyte subtypes in CB related to MO and its relationship with leptin concentration and leptin receptor expression.
Temilayo E. Adeyeye, Laura E. Jones, Edwina Yeung, Pauline Mendola, David A. Lawrence, Shao Lin, Erin M. Bell
doi : 10.1111/aji.13688
Previous studies document an association between mode of delivery (MOD) and allergic conditions in children. Immunoglobulin (Ig) concentrations at birth may play a role. The goal of this study is to assess the impact of MOD on Ig concentrations at delivery from newborn dried blood spots (DBS).
Zaher Merhi, Daniella Emdin, Lisa Bosman, Thomas Incledon, Andre Hugo Smith
doi : 10.1111/aji.13690
Endometriosis, a common and challenging condition, is a pelvic inflammatory condition that causes chronic pelvic pain (CPP) and infertility. Even though standard medical therapies and surgeries can help CPP, a large percentage of women remain symptomatic following the conventional treatments.
Owen Herrock, Evangeline Deer, Lorena M. Amaral, Nathan Campbell, Darby Whitney, Nicole Ingram, Denise C. Cornelius, Ty Turner, Ja'Nasa Hardy-Hardin, George W. Booz, Tarek Ibrahim, Babbette LaMarca
doi : 10.1111/aji.13693
Preeclampsia (PE), new-onset hypertension during pregnancy, is associated with a pro-inflammatory state with activated T cells, cytolytic natural killer (NK) cells, dysregulated complement proteins, and B cells secreting agonistic autoantibodies to the angiotensin II type-1 receptor (AT1-AA).
Yulia P. Milyutina, Alexander V. Arutjunyan, Andrey V. Korenevsky, Sergey A. Selkov, Igor Yu. Kogan
doi : 10.1111/aji.13694
In this review, an attempt was made to substantiate the possibility for neurotrophins to be involved in the development of immune tolerance based on data accumulated on neurotrophin content and receptor expression in the trophoblast and immune cells, in particular, in natural killer cells.
Brien Marie-Eve, Bernier Elsa, Clavel Josianne, Kebiche Yasmine, Jacob Claude-Emilie, Couture Camille, Dal Soglio Dorothée, Girard Sylvie
doi : 10.1111/aji.13679
It is now recognized that SARS-CoV-2 infection and pandemic-related stress impacts maternal health. However, their effects at the maternal-fetal interface are still debated.
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