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Effective Use of Medical Chaperones
Aneesh Agarwal, MBA1; Joseph Han, BS1; David Goldberg, MD, JD1
doi : 10.1001/jamadermatol.2023.0185
May 2023, Vol 159, No. 5, Pages 469-566
JAMA Dermatology—The Year in Review, 2022
Kanade Shinkai, MD, PhD1,2
Public Health and Diagnostic Approaches to Risk Stratification for Melanoma
Alan C. Geller, MPH, RN1; Martin A. Weinstock, MD, PhD2,3
Introducing the JAMA Dermatology Editorial Fellowship
Mya L. Roberson, MSPH, PhD1,2; Kanade Shinkai, MD, PhD3,4
Evaluation of Plasmapheresis vs Immunoglobulin as First Treatment After Ineffective Systemic Corticosteroid Therapy for Patients With Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
Yuki Miyamoto, MD, MPH1,2; Hiroyuki Ohbe, MD, MPH2; Ryosuke Kumazawa, DPH2; Hiroki Matsui, MPH2; Kiyohide Fushimi, MD, PhD3; Hideo Yasunaga, MD, PhD2; Bon Ohta, MD, PhD1
doi : 10.1001/jamadermatol.2023.0035
Importance Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are severe cutaneous adverse reactions, and patients with SJS/TEN frequently require intensive care. However, there is limited evidence on the clinical outcomes of immunomodulating therapy, including plasmapheresis and intravenous immunoglobulin (IVIG) in patients with SJS/TEN.
Safety and Efficacy of Topical Lovastatin Plus Cholesterol Cream vs Topical Lovastatin Cream Alone for the Treatment of Disseminated Superficial Actinic Porokeratosis
Gabriella Santa Lucia, MD, MSCR1; Alan Snyder, MD, MSCR1; Almeera Lateef, BS1; Alex Drohan, MD1; Mathew J. Gregoski, PhD2; Virginia Barton, MD1; Dirk M. Elston, MD1
doi : 10.1001/jamadermatol.2023.0205
Importance Disseminated superficial actinic porokeratosis (DSAP) is an inherited or sporadic disorder of keratinization associated with germline variations. There is no effective standard of care therapy for DSAP, but treatment with topical lovastatin combined with cholesterol cream has shown promise.
Development and Clinical Evaluation of an Artificial Intelligence Support Tool for Improving Telemedicine Photo Quality
Kailas Vodrahalli, BS1; Justin Ko, MD, MBA2; Albert S. Chiou, MD, MBA2; Roberto Novoa, MD2,3; Abubakar Abid, PhD4; Michelle Phung, MS2; Kiana Yekrang, BS2; Paige Petrone, MS2; James Zou, PhD1,5,6,7; Roxana Daneshjou, MD, PhD2,5
doi : 10.1001/jamadermatol.2023.0091
Importance Telemedicine use accelerated during the COVID-19 pandemic, and skin conditions were a common use case. However, many images submitted may be of insufficient quality for making a clinical determination.
Role of Tumor Necrosis Factor–α Inhibitors in the Treatment and Occurrence of Acne
Aaron Gabriel W. Sandoval, MPhil, MSc1; Lauren T. Vaughn, BSc2; Jennifer T. Huang, MD3; John S. Barbieri, MD, MBA4,5
doi : 10.1001/jamadermatol.2023.0269
Importance Tumor necrosis factor–α inhibitors (TNFis) approved to treat several inflammatory diseases are sometimes used off label to treat severe forms of acne that are refractory to conventional therapies. However, use of TNFis can also be followed by acne occurrence, suggesting an association between TNFis and acne. Most of the literature on the topic comprises case reports and series that have not been reviewed in a systematic manner.
Patient Perspectives of Health System Barriers to Accessing Care for Hidradenitis Suppurativa
Leandra A. Barnes, MD1; Neha Shukla, MD2; Maia Paul, MPH2; Isabella de Vere Hunt, MD3,4; Meghan C. Halley, PhD, MPH5; Eleni Linos, MD, MPH, DrPH1,3; Haley B. Naik, MD, MHSc2
doi : 10.1001/jamadermatol.2023.0486
Importance Patient-perceived barriers to hidradenitis suppurativa (HS) care are poorly understood. Understanding health care barriers is a critical first step toward improving care for this population.
Effect of Vitamin D Supplementation on Psoriasis Severity in Patients With Lower-Range Serum 25-Hydroxyvitamin D Levels
Marita Jenssen, MD1,2; Anne-Sofie Furberg, MD, PhD3,4; Rolf Jorde, MD, PhD5; Tom Wilsgaard, PhD2; Kjersti Danielsen, MD, PhD1,2
doi : 10.1001/jamadermatol.2023.0357
Importance Topical vitamin D analogues are routine treatment for psoriasis, but the effect of oral supplementation has not been established.
Efficacy and Safety of Upadacitinib Treatment in Adolescents With Moderate-to-Severe Atopic Dermatitis
Amy S. Paller, MD, MS1; Barry Ladizinski, MD, MPH, MBA2; Pedro Mendes-Bastos, MD3; Elaine Siegfried, MD4; Weily Soong, MD5; Vimal H. Prajapati, MD6,7; Peter Lio, MD8; Jacob P. Thyssen, MD, PhD, DmSci9; Eric L. Simpson, MD, MCR10; Andrew M. Platt, PhD2; Eliza M. Raymundo, MD2; Jianzhong Liu, MD, MS2; Brian M. Calimlim, DrPH, MS2; Xiaohong Huang, PhD2; Yihua Gu, MS2; Xiaofei Hu, PhD2; Yang Yang, PhD2; John C. Su, MB,BS, MEpi11; Min Zheng, MD, PhD12; Kiwako Yamamoto-Hanada, MD, PhD13; Henrique D. Teixeira, PhD2; Alan D. Irvine, MD, DSc14
doi : 10.1001/jamadermatol.2023.0391
Importance Atopic dermatitis onset usually occurs in childhood. Persistence of disease into adolescence and adulthood is common. It is important to evaluate new treatment options in adolescents because of the high unmet need in this population.
Differences in Merkel Cell Carcinoma Presentation and Outcomes Among Racial and Ethnic Groups
Noreen Mohsin, BS1; Mackenzie R. Martin, BA1; Danielle J. Reed, BA1; Serena M. Vilasi, BS1; Lingling Miao, PhD1; Natasha T. Hill, PhD1; Isaac Brownell, MD, PhD1
doi : 10.1001/jamadermatol.2023.0061
Importance Racial and ethnic differences in skin cancer outcomes are understudied. Delineating these differences in Merkel cell carcinoma (MCC) is needed to better understand this rare disease.
Development of a Framework for Addressing Skin Biopsy Tray Waste in Dermatology Clinics
Paige W. Wolstencroft, MD, MS1; Natasha C. Zacher, MD1; Katie Scotellaro, BSN, RN1; Sierra Centkowski, MD1; Bernice Y. Kwong, MD1
doi : 10.1001/jamadermatol.2023.0511
Importance The US health care system generates substantial global waste. Skin biopsies are frequently performed by dermatologists and represent a practical and scalable opportunity for waste reduction interventions in dermatology clinics.
Early Detection and Prognostic Assessment of Cutaneous Melanoma
Mohammed Kashani-Sabet, MD1; Sancy A. Leachman, MD, PhD2; Jennifer A. Stein, MD, PhD3; Jack L. Arbiser, MD, PhD4; Elizabeth G. Berry, MD2; Julide T. Celebi, MD3; Clara Curiel-Lewandrowski, MD5; Laura K. Ferris, MD, PhD6; Jane M. Grant-Kels, MD7,8; Douglas Grossman, MD, PhD9; Rajan P. Kulkarni, MD, PhD2; Michael A. Marchetti, MD10; Kelly C. Nelson, MD11; David Polsky, MD, PhD3; Elizabeth V. Seiverling, MD12; Susan M. Swetter, MD13,14; Hensin Tsao, MD, PhD15,16; Alexandra Verdieck-Devlaeminck, MD2; Maria L. Wei, MD, PhD17,18; Anna Bar, MD2; Edmund K. Bartlett, MD10; Jean L. Bolognia, MD19; Tawnya L. Bowles, MD20; Kelly B. Cha, MD, PhD21; Emily Y. Chu, MD, PhD22; Rebecca I. Hartman, MD, MPH15,16; Elena B. Hawryluk, MD, PhD15,16; Risa M. Jampel, MD23; Lilit Karapetyan, MD, MS24; Meenal Kheterpal, MD25; David H. Lawson, MD4; Philip D. Leming, MD26; Tracey N. Liebman, MD3; Michael E. Ming, MD, MSCE22; Debjani Sahni, MBBS27; Stephanie A. Savory, MD28; Saba S. Shaikh, MD29; Arthur J. Sober, MD15,16; Vernon K. Sondak, MD24; Natalie Spaccarelli, MD30; Richard P. Usatine, MD31; Suraj Venna, MD32; John M. Kirkwood, MD6
doi : 10.1001/jamadermatol.2023.0127
Importance Therapy for advanced melanoma has transformed during the past decade, but early detection and prognostic assessment of cutaneous melanoma (CM) remain paramount goals. Best practices for screening and use of pigmented lesion evaluation tools and gene expression profile (GEP) testing in CM remain to be defined.
Granulomatosis With Polyangiitis Presenting With Strawberry Gums
Sarah E. Fillingim, MS1; Christina Artz, MD2; Pranita Rambhatla, MD2
Carcinoma en Cuirasse
Sarah A. Ibrahim, BA1; Luke S. Wallis, MD2; David C. Reid, MD2
A Pinpoint Orifice on the Glans Penis of a Young Man
Catalina Hasbún, MD1; Ximena Wortsman, MD2,3,4; Jorge Navarrete, MD5
Acquired Diffuse Trichomalacia Associated With Prolonged Use of a Detangling Hairbrush
Woo Chiao Tay, MBBS1; Joyce Siong-See Lee, MBBS1; Etienne Cho Ee Wang, MBBS, PhD1
Assessment of Clinical Response to Anifrolumab in Patients With Refractory Discoid Lupus Erythematosus
Katharina Shaw, MD1; Stephanie Sanchez-Melendez, BS1; Dustin Taylor, MD1; Julia Barker, MD2; Avery LaChance, MD, MPH1; Neda Shahriari, MD1; Ruth Ann Vleugels, MD, MPH, MBA1
Genital Pseudotumor as a Manifestation of Mpox Virus Infection
François-Xavier Blanchet1; Mayda Rahi, MD2; Marie Merlant, MD1; Mathilde Gare, MD2; Florence Brunet-Possenti, MD, PhD1; Vincent Descamps, MD, PhD1; Fabrice Bouscarat, MD1
Treatment of Eosinophilic Annular Erythema With Benralizumab
Fernando Moro-Bolado, MD1; Laura MartÃnez-Montalvo, MD1; Omar Al-Wattar-Ceballos, MD1; Pedro Ã�ngel Galindo-Bonilla, MD2; Mónica GarcÃa-Arpa, MD1
