Euscher, Elizabeth D. MD *; Marques-Piubelli, Mario L. MD *; Ramalingam, Preetha MD *; Wistuba, Ignacio MD *; Lawson, Barrett C. MD *; Frumovitz, Michael MD +; Malpica, Anais MD *
doi : 10.1097/PAS.0000000000002039
Volume 47(6) pgs. 635-737 June 2023
AB Extrauterine mesonephric-like carcinoma (ExUMLC) shares histologic, immunohistochemical (IHC), and molecular (MOL) features with endometrial mesonephric-like carcinoma (EnMLC). Its rarity and histologic overlap with Mullerian carcinomas contribute to underrecognition of ExUMLC.
Graham, Danielle S. MD, MBA *; Qorbani, Amir MD +,++; Eckardt, Mark A. MD *,[S],[//]; Klingbeil, Kyle D. MD *; Chen, Lucia Y. MS [P]; Chopra, Shefali MD #; Eilber, Fritz C. MD *,**; Dry, Sarah M. MD +,**
doi : 10.1097/PAS.0000000000002037
Subjective, varying criteria identify "low-grade" dedifferentiation in well-differentiated/dedifferentiated liposarcoma (WD/DDLPS). The value of mitotic rate (MR) in defining DDLPS is not confirmed.
Baneckova, Martina MD, PhD *,+; Thompson, Lester D.R. MD ++; Hyrcza, Martin D. MD, PhD [S]; Vanecek, Tomas PhD [//]; Agaimy, Abbas MD, PhD [P]; Laco, Jan MD, PhD #; Simpson, Roderick H.W. MD **; Di Palma, Silvana MD ++; Stevens, Todd M. MD ++++; Brcic, Luka MD, PhD [S][S]; Etebarian, Arghavan DDS, MSc [//][//]; Dimnik, Katarina MD [P][P]; Majewska, Hanna MD ##; Starek, Ivo MD, PhD ***; O'Regan, Esther MD, PhD +++; Salviato, Tiziana MD ++++++; Helliwell, Tim MD [S][S][S]; Horakova, Marketa MD, PhD *,+; Biernat, Wojciech MD, PhD [//][//][//]; Onyuma, Timothy MD [P][P][P]; Michal, Michal MD *,+; Leivo, Ilmo MD, PhD ###; Skalova, Alena MD, PhD *,+
Shi, Chanjuan MD, PhD *; Chen, Wei MD *; Davis, Richard MD *; Morse, Michael A. MD +
doi : 10.1097/PAS.0000000000002038
AB In this study, we evaluated venous invasion and its association with survival in patients with resected pancreatic neuroendocrine tumor (PanNET). Surgical Pathology Archives were searched for pancreatectomies performed for PanNET between October 1, 2005, and December 31, 2019.
Bosse, Yohan PhD *,+; Gagne, Andreanne MD, PhD *; Althakfi, Wajd A. MD ++; Orain, Michele *; Couture, Christian MD, MSc *; Trahan, Sylvain MD *; Page, Sylvain MD *; Joubert, David PhD [S]; Fiset, Pierre O. MD, PhD [//]; Desmeules, Patrice MD, MSc *; Joubert, Philippe MD, PhD *
doi : 10.1097/PAS.0000000000002040
AB Tumor grading enables better management of patients and treatment options. The International Association for the Study of Lung Cancer (IASLC) Pathology Committee has recently released a 3-tier grading system for invasive pulmonary adenocarcinoma consisting of predominant histologic patterns plus a cutoff of 20% of high-grade components including solid, micropapillary, and complex glandular patterns.
Obiorah, Ifeyinwa E. MD, PhD; Aguilera, Nadine S. MD; Gru, Alejandro MD; Courville, Elizabeth L. MD
doi : 10.1097/PAS.0000000000002035
AB Ultrasensitive bright-field RNA in situ hybridization (BRISH) can be used to detect lower levels of light chain expression than immunohistochemical stains or conventional colorimetric RNA in situ hybridization.
Samaratunga, Hemamali MBBS, FRCPA *,+; Egevad, Lars MD, PhD ++; Yaxley, John W. MBChB, FRACS +,[S]; Johannsen, Shulammite MSc *; Le Fevre, Ian K. MBBS, FRCPA *; Perry-Keene, Joanna L. MBBS, FRCPA *; Gianduzzo, Troy MBBS,FRACS +,[S]; Chabert, Charles MBBS, FRACS [S]; Coughlin, Gregory MBBS, FRACS [S]; Parkinson, Robert MBBS, FRACS [S]; Kua, Boon MBBS, FRACS [S]; Yaxley, William MBBS [//]; Delahunt, Brett MD, FRCPA *,[P]
doi : 10.1097/PAS.0000000000002042
AB Anterior prostate cancer (APC) has been considered an indolent tumor, most commonly arising in the transition zone (TZ). More recently, detection of APC has been facilitated through multiparametric magnetic resonance imaging and improved biopsy techniques, enabling earlier detection.
Argani, Pedram MD *,+; Dickson, Brendan C. MD ++; Gross, John M. MD *,+; Matoso, Andres MD *,+,[S]; Baraban, Ezra MD *,+; Antonescu, Cristina R. MD [//]
doi : 10.1097/PAS.0000000000002036
AB Ossifying fibromyxoid tumors (OFMTs) are rare mesenchymal neoplasms which typically present in the superficial subcutaneous tissues and have not been reported to arise in visceral organs.
Devins, Kyle M. MD *; Attygalle, Ayoma D. FRCPath, PhD +; Croce, Sabrina MD, PhD ++; Vroobel, Katherine MA, FRCPath +; Oliva, Esther MD *; McCluggage, W. Glenn FRCPath [S]
doi : 10.1097/PAS.0000000000002041
AB Uterine endometrial stromal sarcomas (ESS) with YWHAE::NUTM2 gene fusions are typically morphologically high-grade tumors composed of atypical round cells, sometimes associated with a low-grade fibromyxoid component; they are currently included in the category of high-grade ESS (HGESS).
Kallen, Michael E. MD *; Michal, Michael MD, PhD +; Meyer, Anders MD ++; Suster, David I. MD [S]; Olson, Nicholas J. MD [//],[P]; Charville, Gregory W. MD, PhD #; Perret, Raul MD, MSc **; Gross, John M. MD, MS ++
doi : 10.1097/PAS.0000000000002044
AB Calcified chondroid mesenchymal neoplasm is a term proposed for tumors with a spectrum of morphologic features, including cartilage/chondroid matrix formation, that frequently harbor FN1 gene fusions.
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