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JPGN and the Year 2022.
Belli, Dominique C. MD; Gupta, Sandeep K. MD
doi : 10.1097/MPG.0000000000003790
Volume 77(1) pgs. 1-146,e1-e12 July 2023
Catch-Up Growth in Infants and Young Children With Faltering Growth: Expert Opinion to Guide General Clinicians.
Cooke, Richard MD *; Goulet, Olivier MD, PhD +; Huysentruyt, Koen MD, PhD ++; Joosten, Koen MD, PhD [S]; Khadilkar, Anuradha Vaman MD [//]; Mao, Meng MD [P]; Meyer, Rosan PhD #,**; Prentice, Andrew M. PhD ++; Singhal, Atul MD, MRCP ++++
doi : 10.1097/MPG.0000000000003784
AB Faltering growth (FG) is a problem regularly seen by clinicians in infants and young children (<2 years of age). It can occur due to non-disease-related and disease-related causes and is associated with a wide range of adverse outcomes, including shorter-term effects such as impaired immune responses and increased length of hospital stay, and longer-term consequences, including an impact on schooling and cognitive achievements, short stature, and socioeconomic outcomes.
Novel Serum Biomarkers Associated With Pediatric Hepatic Encephalopathy: A Systematic Review.
Krishnan, Kavita BS *; Rao, Mahil MD, PhD +; Chang, Nathan MSN +; Casazza, May MSN ++; Rasmussen, Lindsey K. MD +
doi : 10.1097/MPG.0000000000003801
The pathophysiology of pediatric hepatic encephalopathy (HE) is not well understood. Various serum biomarkers associated with HE may provide insight into its pathology, but their use and interpretation in clinical practice for diagnosis and prognostication remain undetermined.
Pediatric Intestinal Pseudo-Obstruction: An International Survey on Diagnostic and Management Strategies in the European Reference Network for Rare Inherited and Congenital Anomalies Intestinal Failure Teams.
Mutanen, Annika MD, PhD *; Demirok, Aysenur MD +; Wessel, Lucas MD ++; Tabbers, Merit MD, PhD +; on behalf of ERNICA IF Working Group
doi : 10.1097/MPG.0000000000003788
Pediatric intestinal pseudo-obstruction (PIPO) management is based on nutritional, medical, and surgical care while available evidence is scarce.
Gut Microbiota Dysbiosis in Suspected Food Protein Induced Proctocolitis-A Prospective Comparative Cohort Trial.
Wurm, Philipp PhD *; Stampfer, Laura MD +; Greimel, Theresa MD +; Leitner, Eva PhD ++; Zechner, Ellen L. PhD [S],[//]; Bauchinger, Sebastian MD +; Hauer, Almuthe C. MD +; Gorkiewicz, Gregor MD *; Hogenauer, Christoph MD [P]; Hoffmann, K. Martin MD +,#
doi : 10.1097/MPG.0000000000003789
In infants with suspected food protein induced proctocolitis (sFPIP) only a minority of patients are finally diagnosed with the disease following diagnostic dietary intervention (DDI). There is a need for a pathophysiological explanation for the cause of hematochezia in the majority of sFPIP infants. Methods: We prospectively recruited infants with sFPIP and healthy controls.
A Multidisciplinary Approach to Infants With GERD-Like Symptoms: A New Paradigm.
Fishbein, Mark H. MD *; Kronberg, Jessica MOT, OTR/L +; Alvarado, Stephanie MS, OTR/L ++; Bohm, Diana MS, CCC-SLP [S]; Ideran, Patricia OTR/L, CEIM [S]; Scarborough, Donna R. PhD, CCC-SLP-BCS-S [//]
doi : 10.1097/MPG.0000000000003802
Infants with gastroesophageal reflux disease (GERD)-like symptoms have been classically defined as having a wide array of symptoms.
The Prevalence of Bowel and Bladder Function During Early Childhood: A Population-Based Study.
Verkuijl, Sanne J. MD, PhD *,+; Trzpis, Monika PhD +; Broens, Paul M.A. MD, PhD *,+
doi : 10.1097/MPG.0000000000003804
Our primary aim was to determine bowel and bladder function in children aged 1 month to 7 years in the general Dutch population. Second, we aimed to identify demographic factors associated with the presence of bowel and bladder dysfunction, and their coexistence.
Gastrointestinal Symptoms Profile in Gastroparesis Compared to Other Functional and Organic Gastrointestinal Diseases.
Varni, James W. PhD *,+; Chumpitazi, Bruno P. MD, MPH ++,[S]; Febo-Rodriguez, Liz MD [//]; Shulman, Robert J. MD ++,[S]
doi : 10.1097/MPG.0000000000003806
The primary objective was to compare the patient-reported gastrointestinal symptoms profiles of pediatric patients with gastroparesis to pediatric patients with 1 of 7 other functional gastrointestinal disorders and organic gastrointestinal diseases using the Pediatric Quality of Life Inventory (PedsQL) Gastrointestinal Symptoms Scales.
Risk Factors of Cancer in Pediatric-Onset Inflammatory Bowel Disease in Denmark and Finland.
Malham, Mikkel MD, PhD *,+,++; Jansson, Sabine MD *,+; Malmborg, Petter MD, PhD [S],[//]; Olen, Ola MD, PhD [S],[//]; Paerregaard, Anders *,+; Virta, Lauri J. [P]; Jakobsen, Christian *,+; Kolho, Kaija-Leena MD, DMSc #; Wewer, Vibeke MD, PhD *,+
doi : 10.1097/MPG.0000000000003781
Pediatric-onset inflammatory bowel disease (pIBD) increases the risk of developing several different cancer forms. In this case-control study, we aimed to assess the impact of medical treatment and disease activity on the risk of developing disease-associated cancer (DAC) and treatment-associated cancer (TAC).
Endoscopic Balloon Dilatation in Pediatric Crohn Disease: An IBD Porto Group Study.
Ledder, Oren MD *; Viala, Jerome MD +; Serban, Daniela Elena MD ++; Urlep, Darja MD [S]; De Ridder, Lissy MD [//]; Martinelli, Massimo MD [P]; Romano, Claudio MD #; Church, Peter MD **; Griffiths, Chris MD ++; Oliva, Salvatore MD ++++; Basude, Dharam MD [S][S]; Sharma, Shishu MD [//][//]; Thomson, Mike MD [//][//]
doi : 10.1097/MPG.0000000000003783
Endoscopic balloon dilatation (EBD) has been shown to be effective and safe in adults with stricturing Crohn disease (CD) yet pediatric data is sparse.
The Pediatric Crohn Disease Morbidity Index (PCD-MI): Development of a Tool to Assess Long-Term Disease Burden Using a Data-Driven Approach.
Ashton, James J. PhD *,+; Gurung, Abhilasha MRCPCH +; Davis, Cai BSc ++; Seaby, Eleanor G. BMBS *; Coelho, Tracy PhD +; Batra, Akshay MD +; Afzal, Nadeem A. MD +; Ennis, Sarah PhD *; Beattie, R. Mark FRCPCH +
doi : 10.1097/MPG.0000000000003793
Heterogeneity and chronicity of Crohn disease (CD) make prediction of outcomes difficult. To date, no longitudinal measure can quantify burden over a patient's disease course, preventing assessment and integration into predictive modeling.
The Characteristics of Isolated Bulb Celiac Disease in Children.
Behl, Supriya MSc *; Khan, Muhammad Rehan MD +; Ismail, Yasmine MBBCh ++; Swantek, Courtney MD [S]; Chen, Zong-Ming (Eric) MD, PhD [//]; Murray, Joseph A. MD [P]; Absah, Imad MD ++
doi : 10.1097/MPG.0000000000003799
Mucosal injury in celiac disease (CD) patients can be patchy, and up to 12% of CD patients can have mucosal changes limited to the duodenal bulb.
Characterization of Eosinophilic Esophagitis in Infants and Toddlers.
Hirsch, Suzanna MD *; Cohen, Alexandra BA *; Rahbar, Reza DMD, MD +; Rubinstein, Eitan MD *; Rosen, Rachel MD, MPH *
doi : 10.1097/MPG.0000000000003803
The objective of this study is to determine demographic and clinical characteristics of infants and toddlers <2 years with eosinophilic esophagitis (EoE) and to assess treatment response in this rarely studied pediatric age group.
Reproducibility and Generalizability of the Web-Based Tool to Predict Lamina Propria Fibrosis in Eosinophilic Esophagitis.
Hiremath, Girish MD, MPH *; Arva, Nicoleta C. MD, PhD +; Wechsler, Joshua B. MD, MS ++
doi : 10.1097/MPG.0000000000003810
AB We investigated reproducibility and generalizability of the recently developed web-based model to predict lamina propria fibrosis (LPF) in esophageal biopsies with inadequate lamina propria (LP) from patients with eosinophilic esophagitis (EoE) using an independent dataset (N = 183).
Matrix Metalloproteinase-7 and Osteopontin Serum Levels as Biomarkers for Biliary Atresia.
Aldeiri, Bashar PhD *; Si, Tengfei PhD +; Huang, Zhenlin PhD +; Torner, Nuria MD +++; Ma, Yun PhD +; Davenport, Mark MD *,+; Hadzic, Nedim MD +++
doi : 10.1097/MPG.0000000000003792
Matrix metallopeptidase-7 (MMP-7) and osteopontin (OPN) are important components in the pathophysiology of fibrosis in biliary atresia (BA).
Prevalence of Elevated ALT in Adolescents in the US 2011-2018.
Mischel, Anna K. BA *; Liao, Zhengxu MS +; Cao, Fangyi MS +; Dunn, Winston MD ++; Lo, Joan C. MD [S],[//]; Newton, Kimberly P. MD *,[P]; Goyal, Nidhi P. MD, MPH *,[P]; Yu, Elizabeth L. MD *,[P]; Schwimmer, Jeffrey B. MD *,[P]
doi : 10.1097/MPG.0000000000003795
The objective of this study is to characterize suspected nonalcoholic fatty liver disease (NAFLD) using elevated alanine aminotransferase (ALT) in a diverse and nationally representative cohort of adolescents and to characterize higher ALT elevation in adolescents with obesity.
Liver Disease in GLIS3 Mutations: Transplant Considerations and Bile Duct Paucity on Explant Histology.
Couper, Michael R. MBChB, FRACP *; Brown, Rachel M. MD, FRCPath +; Gupte, Girish MD, FRCPCH *; Perera, M. Thamara P.R. MD, FRCS *; Kelgeri, Chayarani MD, MRCPCH *
doi : 10.1097/MPG.0000000000003773
AB GLI-similar 3 (GLIS3) gene mutation heterozygosity is characterized by neonatal diabetes and hypothyroidism. It has wide phenotypic variability. Liver disease is prevalent, and its complications in some phenotypes are life-limiting.
Etiology and Outcome of Adult and Pediatric Acute Liver Failure in Europe.
Lenz, Dominic MD *,+; Horby Jorgensen, Marianne MD +,++; Kelly, Deirdre MD +,[S]; Cardinale, Vincenzo MD +,[//]; Geerts, Anja MD +,[P]; Goncalves Costa, Isabel MD +,#; Fichtner, Alexander MD *,+; Garbade, Sven F. PhD *,+; Hegen, Bianca MD +,**; Hilberath, Johannes MD +,++; de Kleine, Ruben MD +,++++; Kupcinskas, Limas MD +,[S][S]; McLin, Valerie MD +,[//][//]; Niesert, Moritz MD *,+; Prado Gonzalez, Veronica MD +,[P][P]; Sturm, Ekkehard MD, PhD +,++; Staufner, Christian MD *,+; Tjwa, Eric MD +,##; Willemse, Jose MSc +,***; Zecher, Britta F. MD +,+++; Larsen, Fin Stolze MD +,++++++; Sebode, Marcial MD +,+++; Ytting, Henriette MD +,[S][S][S],[//][//][//]
doi : 10.1097/MPG.0000000000003777
AB Acute liver failure (ALF) is rare but life-threatening. Common causes include intoxications, infections, and metabolic disorders. Indeterminate etiology is still frequent
Improving Hepatitis B Screening at Family Health Centers Using Quality Improvement and Electronic Medical Record Tools.
Huang, Jeannie S. MD, MPH *; Cruz, Rusvelda MPH *; Schwarz, Kathleen B. MD *; Tran, Thao MD +
doi : 10.1097/MPG.0000000000003791
AB Chronic hepatitis B viral (HBV) infection is associated with significant morbidity and mortality with endemic areas carrying most of the global burden of HBV disease.
Impact of Trainee Involvement on Pediatric ERCP Procedures: Results From the Pediatric ERCP Initiative.
Gupta, Rekha MD *; Khalaf, Racha T. MD +; Morrison, John MD, PhD ++; Amankwah, Ernest PhD ++; Ruan, Wenly MD [S]; Fishman, Douglas S. MD ||; Barth, Bradley A. MD [P]; Liu, Quin Y. MD #; Giefer, Matthew MD **; Kim, Kyung Mo MD ++; Martinez, Mercedes MD ++++; Dall'oglio, Luigi MD [S][S]; Torroni, Filippo MD [S][S]; De Angelis, Paola MD [S][S]; Faraci, Simona MD [S][S]; Bitton, Sam MD ||||; Dua, Kulwinder MD [P][P]; Werlin, Steven MD [P][P]; Gugig, Roberto MD ##; Huang, Clifton MD ***; Mamula, Petar MD +++; Quiros, J. Antonio MD ++++++; Zheng, Yuhua MD [S][S][S]; Piester, Travis MD [S][S][S]; Grover, Amit MD ||||||; Fox, Victor L. MD ||||||; Wilsey, Michael MD ++; Troendle, David M. MD [P]
doi : 10.1097/MPG.0000000000003782
AB This study examines the role of trainee involvement with pediatric endoscopic retrograde cholangiopancreatography (ERCP) and whether it affects the procedure's success, post-procedural adverse outcomes, and duration.
Laparoscopic Sleeve Gastrectomy Versus One Anastomosis Gastric Bypass in Adolescents With Obesity.
Sorek, Adi MD *; Eldar, Sukhotnik Meron MD +; Cohen, Shlomi MD ++; Mazkeret Mayer, Inbar RD ++; Sukhtnik, Igor MD [S]; Lubetzky, Ronit MD *; Moran-Lev, Hadar MD *,++
doi : 10.1097/MPG.0000000000003780
Large studies comparing outcomes between laparoscopic sleeve gastrectomy (LSG) and one anastomosis gastric bypass (OAGB) are scarce and involve adult populations.
Patient-Reported Outcome Measures That Describe the Feeding Skills Domain for Pediatric Feeding Disorder: A Clinimetric Review.
Marshall, Jeanne PhD, CPSP *,+; Gosa, Memorie M. PhD, CCC-SLP, BCS-S ++; Dodrill, Pamela PhD, CCC-SLP, BCS-S [S]||
doi : 10.1097/MPG.0000000000003798
Pediatric feeding disorder (PFD) is defined as "impaired oral intake that is not age-appropriate, and is associated with medical, nutritional, feeding skill, and/or psychosocial dysfunction."
Fatty Acid Percentage Distribution in Complex Lipids of Breast Milk From Mothers on a Low Docosahexaenoic Acid Diet.
Gonzalez, Horacio F. MD *; Malpeli, Agustina MSc Nutr *; Fasano, Victoria DMath *,+; Pescio, Lucila G. DChem ++,[S]; Sterin-Speziale, Norma B. DChem [S],[//]; Visentin, Silvana MSc Nutr *
doi : 10.1097/MPG.0000000000003775
AB The aim of this study was to assess the fatty acid (FA) percentage distribution in complex lipids of breast milk from mothers on a low docosahexaenoic acid (DHA) diet.
A Rare Entity With Dangerous Potential-Clinical Images From a Case of An Isolated Congenital Lumbar Hernia.
Ali, Syed Waqas FCPS *; Usmani, Shajie Ur Rehman MBBS *; Khan, Muhammad Arif Mateen FRCS *
