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سفارش
Botulinum neurotoxin A ameliorates depressive-like behavior in a reserpine-induced Parkinson’s disease mouse model via suppressing hippocampal microglial engulfment and neuroinflammation
Yang Li, Qiao Yin, Qi Li, An-ran Huo, Ting-ting Shen, Jia-qian Cao, Chun-feng Liu, Tong Liu, Wei-feng Luo & Qi-fei CongÂ
doi : 10.1038/s41401-023-01058-x
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Up-regulation of microglial chemokine CXCL12 in anterior cingulate cortex mediates neuropathic pain in diabetic mice
Zi-hua Song, Xiang-Jie Song, Chen-ling Yang, Peng Cao, Yu Mao, Yan Jin, Meng-yun Xu, Hai-tao Wang, Xia Zhu, Wei Wang, Zhi Zhang & Wen-juan TaoÂ
doi : 10.1038/s41401-022-01046-7
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Dual-omics reveals temporal differences in acute sympathetic stress-induced cardiac inflammation following α1 and β-adrenergic receptors activation
Di Zhang, Ming-ming Zhao, Ji-min Wu, Rui Wang, Gang Xue, Yan-bo Xue, Ji-qi Shao, You-yi Zhang, Er-dan Dong, Zhi-yuan Li & Han XiaoÂ
doi : 10.1038/s41401-022-01048-5
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Notoginsenoside R1 protects against myocardial ischemia/reperfusion injury in mice via suppressing TAK1-JNK/p38 signaling
Jing-jing Zeng, Han-qing Shi, Fang-fang Ren, Xiao-shan Zhao, Qiao-ying Chen, Dong-juan Wang, Lian-pin Wu, Mao-ping Chu, Teng-fang Lai & Lei LiÂ
doi : 10.1038/s41401-023-01057-y
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Cell-autonomous effect of cardiomyocyte branched-chain amino acid catabolism in heart failure in mice
Jia-yu Yu, Nancy Cao, Christoph D. Rau, Ro-Po Lee, Jieping Yang, Rachel J. Roth Flach, Lauren Petersen, Cansheng Zhu, Yea-Lyn Pak, Russell A. Miller, Yunxia Liu, Yibin Wang, Zhaoping Li, Haipeng Sun & Chen GaoÂ
doi : 10.1038/s41401-023-01076-9
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CB2R agonist GW405833 alleviates acute liver failure in mice via inhibiting HIF-1α-mediated reprogramming of glycometabolism and macrophage proliferation
Sheng-lan Cai, Xue-gong Fan, Jie Wu, Yang Wang, Xing-wang Hu, Si-ya Pei, Yi-xiang Zheng, Jun Chen, Yan Huang, Ning Li & Ze-bing HuangÂ
doi : 10.1038/s41401-022-01037-8
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Bavachin protects against diet-induced hepatic steatosis and obesity in mice
Xiang Wei, Li Lin, Qian-qian Yuan, Xiu-yun Wang, Qing Zhang, Xiao-min Zhang, Ke-chao Tang, Man-yu Guo, Ting-yu Dong, Wei Han, Da-ke Huang, Yin-liang Qi, Mei Zhang & Hua-bing ZhangÂ
doi : 10.1038/s41401-023-01056-z
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Skullcapflavone II, a novel NQO1 inhibitor, alleviates aristolochic acid I-induced liver and kidney injury in mice
Ya-ping Dong, Shu-zhen Chen, Hui-si He, Zhuo-ran Sun, Li-xuan Jiang, Yan-qiu Gu, Ying Zhang, Fei Feng, Chun Chen, Zhe-cai Fan, Xiao-fei Chen, Wen Wen & Hong-yang WangÂ
doi : 10.1038/s41401-023-01052-3
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Kaempferide ameliorates cisplatin-induced nephrotoxicity via inhibiting oxidative stress and inducing autophagy
Yan-fei Shao, Bing-bing Tang, Yu-hui Ding, Chun-yan Fang, Ling Hong, Chun-xiao Shao, Zhao-xu Yang, Yue-ping Qiu, Jin-cheng Wang, Bo Yang, Qin-jie Weng, Jia-jia Wang & Qiao-jun HeÂ
doi : 10.1038/s41401-023-01051-4
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Long-term passaging of pseudo-typed SARS-CoV-2 reveals the breadth of monoclonal and bispecific antibody cocktails
Hang Ma, Hui-fang Zong, Jun-jun Liu, Ya-li Yue, Yong Ke, Yun-ji Liao, Hao-neng Tang, Lei Wang, Shu-sheng Wang, Yun-sheng Yuan, Ming-yuan Wu, Yan-lin Bian, Bao-hong Zhang, Hai-yang Yin, Hua Jiang, Tao Sun, Lei Han, Yue-qing Xie & Jian-wei ZhuÂ
doi : 10.1038/s41401-022-01043-w
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143D, a novel selective KRASG12C inhibitor exhibits potent antitumor activity in preclinical models
Lan-song Xu, Su-xin Zheng, Liang-he Mei, Ke-xin Yang, Ya-fang Wang, Qiang Zhou, Xiang-tai Kong, Ming-yue Zheng, Hua-liang Jiang & Cheng-ying XieÂ
doi : 10.1038/s41401-023-01053-2
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Inhibiting the transcription and replication of Ebola viruses by disrupting the nucleoprotein and VP30 protein interaction with small molecules
Yan-hong Ma, Xu Hong, Fang Wu, Xin-feng Xu, Rui Li, Jin Zhong, Yao-qi Zhou, Shu-wen Liu, Jian Zhan & Wei XuÂ
doi : 10.1038/s41401-023-01055-0
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Computationally guided discovery of novel non-steroidal AR-GR dual antagonists demonstrating potency against antiandrogen resistance
Xin Chai, Xue-ping Hu, Xin-yue Wang, Hua-ting Wang, Jin-ping Pang, Wen-fang Zhou, Jia-ning Liao, Lu-hu Shan, Xiao-hong Xu, Lei Xu, Hong-guang Xia, Ting-jun Hou & Dan LiÂ
doi : 10.1038/s41401-022-01038-7
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Author Correction: Shenqi Fuzheng Injection attenuates irradiation-induced brain injury in mice via inhibition of the NF-κB signaling pathway and microglial activation
Jian Zhang, Fan Tong, Qian Cai, Ling-juan Chen, Ji-hua Dong, Gang Wu & Xiao-rong DongÂ
doi : 10.1038/s41401-023-01050-5
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