Journal of Ethnopharmacology

The traditional use of Southern African medicinal plants to alleviate fever and their antipyretic activities

I.E. Cock a,b, N. Luwaca c, S.F. Van Vuuren

doi : 10.1016/j.jep.2022.115850

Volume 303, 1 March 2023, 115850

Knowledge on ethnogynaecology of Indian Tribes- a comprehensive review

Saranya Surendran a, Priya Prasannan a, Yasotha Jeyaram b, Venkatesh Palanivel a, Arjun Pandian c,d, Raju Ramasubbu

doi : 10.1016/j.jep.2022.115880

Volume 303, 1 March 2023, 115880

The benefits of propolis in periodontal therapy. A scoping review of preclinical and clinical studies

Angel Luque-Bracho a, Yasmin Rosales a, Andrea Vergara-Buenaventura

doi : 10.1016/j.jep.2022.115926

Volume 303, 1 March 2023, 115926

The genus Landolphia P.Beauv. (Apocynaceae): A comprehensive review on its ethnobotanical utilizations, pharmacology and nutritional potential

Christin BaumgÂ¨artel *, Thea LautenschlÂ¨ager

doi : 10.1016/j.jep.2022.115946

Volume 303, 1 March 2023, 115946

Impatiens balsamina: An updated review on the ethnobotanical uses, phytochemistry, and pharmacological activity

Huiqin Qian a, Bailing Wang b, Jinshuo Ma a, Chunyan Li a, Qingjin Zhang a, Yongheng Zhao

doi : 10.1016/j.jep.2022.115956

Volume 303, 1 March 2023, 115956

Recent discovery of tyrosinase inhibitors in traditional Chinese medicines and screening methods

Jiaxu Li a,1, Chenyue Li a,1, Xin Peng c, Shaoping Li d, Bingrui Liu b,**, Chu Chu a,*

doi : 10.1016/j.jep.2022.115951

Volume 303, 1 March 2023, 115951

Ethnopharmacology and biological activities of the Aizoaceae

B. Kalicharan a,b, Y. Naidoo a, J. van Staden

doi : 10.1016/j.jep.2022.115988

Volume 303, 1 March 2023, 115988

A comparison review of Hehuan flowers and Hehuan bark on the traditional applications, phytochemistry and pharmacological effects

Pengfei Lu a, Chengzhong Zhang a, Jiadong Zheng b, Chunyan Li a, Qijin Zhang a, Baokang Huang

doi : 10.1016/j.jep.2022.116002

Volume 303, 1 March 2023, 116002

Ethnobotanical uses, phytochemistry and pharmacology of pantropical genus Zanthoxylum L. (Rutaceae): An update

Elizabeth Syowai Mutinda a,b,c, Festus Kimutai a,b,c, Elijah Mbandi Mkala a,b,c, Emmanuel Nyongesa Waswa a,b,c, Wyclif Ochieng Odago a,b,c, Consolata Nanjala a,b,c, Caroline Njambi Ndungu d, Moses Kirega Gichua d, Moses Muguci Njire d, Robert Wahiti Gituru d, Guang-Wan Hu

doi : 10.1016/j.jep.2022.115895

Volume 303, 1 March 2023, 115895

Gut microbiota: A new target for traditional Chinese medicine in the treatment of depression

Boru Li a, Meijing Xu a, Yu Wang a, Lijin Feng a, Hang Xing a,b,**, Kuo Zhang

doi : 10.1016/j.jep.2022.116038

Volume 303, 1 March 2023, 116038

Compatibility between cold-natured medicine CP and hot-natured medicine AZ synergistically mitigates colitis mice through attenuating inflammation and restoring gut barrier

Yan-Yang Li , Yue-Xian He , Ye-Qun Wu , Chang Liu , Ling-Zhi Ren , Xiang-Yi Lu , Yu-Mei Wang **, Yang Yu

doi : 10.1016/j.jep.2022.115902

Volume 303, 1 March 2023, 115902

Xinfuli granule alleviates metabolic remodeling through inhibition of endoplasmic reticulum stress and mitochondrial injury in heart failure

Yan-Ni Su, Pei-Pei Lu, Si-Yu Yan, Xuan-Tong Guo, Jie Ma, Cai-Xia Guo **, Li-Hong Ma

doi : 10.1016/j.jep.2022.115782

Volume 303, 1 March 2023, 115782

Integrating metabolomics and network pharmacology to investigate Panax japonicus prevents kidney injury in HFD/STZ-induced diabetic mice

Tingting Wang a, Xiaoting Huang b, Kefeng Zhai e, Jialin Yu c, Jiaxi Li d, Hong Duan e, Jinhong Liu a, Zhuojian Lu a, Jia Guo b,f,**, Fei Li

doi : 10.1016/j.jep.2022.115893

Volume 303, 1 March 2023, 115893

Apoptosis induction of essential oils from Artemisia arborescens L. in human prostate cancer cells

Alessandra Russo a,*, Adriana Graziano b, Maurizio Bruno c, Venera Cardile b,**, Daniela Rigano

doi : 10.1016/j.jep.2022.115929

Volume 303, 1 March 2023, 115929

Integrated proteomics and metabolomics reveal variations in pulmonary fibrosis development and the potential therapeutic effect of Shuangshen Pingfei formula

Yeqing Chen **, Xiaolin Li , Xinsheng Fan

doi : 10.1016/j.jep.2022.115894

Volume 303, 1 March 2023, 115894

Pharmacokinetic characteristics of emodin in polygoni Multiflori Radix Praeparata

Dongpeng Wang a,b,1, Jufeng Duan a,1, Xiao-Jing Chen a, Kaiqi Liu a, Yingying Guo a, Run Shi c, Sha Li d, Ming Liu a, Lijun Zhao a, Bei Li a, Hongtao Liu b, Minglun Li e, Yibin Feng f, Hongliang Li a,**, Xuanbin Wang a,*

doi : 10.1016/j.jep.2022.115945

Volume 303, 1 March 2023, 115945

Integration of pharmacodynamics, network pharmacology and metabolomics to elucidate effect and mechanism of Artemisia capillaris Thunb. in the treatment of jaundice

Qing Yang a,1, Xubo Wu b,1, Zhiyu Pan b, Ruifang Guan a, Ping Yang a, Ye Liu a, Xiaolei Yang a, Wandi Du a, Jingru Liang a, Jiarong Hu a, Weimin Cai a, Guo Ma

doi : 10.1016/j.jep.2022.115943

Volume 303, 1 March 2023, 115943

Validation of traditional claims of anti-arthritic efficacy of trans-Himalayan snow mountain garlic (Allium ampeloprasum L.) extract using adjuvant-induced arthritis rat model: A comparative evaluation with normal garlic (Allium sativum L.) and dexamethasone

Bhupinder Kaur a,b, Nitish Kumar a, Manoj K. Patel a, Kanwaljit Chopra b, Shweta Saxena

doi : 10.1016/j.jep.2022.115939

Volume 303, 1 March 2023, 115939

Phytochemical investigation, molecular docking studies and DFT calculations on the antidiabetic and cytotoxic activities of Gmelina philippensis CHAM

Hanaa M. Sayed a, Amany S. Ahmed a,b, Iman SA. Khallaf c,*, Wesam S. Qayed d, Anber F. Mohammed e, Hanan S.M. Farghaly f, Ayman Asem

doi : 10.1016/j.jep.2022.115938

Volume 303, 1 March 2023, 115938

Genotoxicity and toxicological evaluations of Brazilian red propolis oral ingestion in a preclinical rodent model

Jennyfer Andrea Aldana-Mej?a a, Aline Mayrink de Miranda a, Gari Vidal Ccana-Ccapatinta a, Luciana Silva de Ara?jo a, Victor Pena Ribeiro a, Caroline Arruda a, Samuel Nascimento b, Iara Squarisi b, TÂ´abata Esperandim b, Karoline S. de Freitas b, Saulo D. Ozelin b, Denise Crispim Tavares b, Fernando Silva Ramalho c, Jairo Kenupp Bastos

doi : 10.1016/j.jep.2022.115920

Volume 303, 1 March 2023, 115920

Taxifolin-3-O-glucoside from Osbeckia nepalensis Hook. mediates antihyperglycemic activity in CC1 hepatocytes and in diabetic Wistar rats via regulating AMPK/G6Pase/PEPCK signaling axis

Shalini Gurumayum a,b, Simanta Bharadwaj a, Yunus Sheikh a, Sagar R. Barge a, Kangkon Saikia c, Deepsikha Swargiary a, Semim Akhtar Ahmed a, Debajit Thakur c, Jagat C. Borah

doi : 10.1016/j.jep.2022.115936

Volume 303, 1 March 2023, 115936

Explore bioactive ingredients and potential mechanism of Houpo Mahuang decoction for chronic bronchitis based on UHPLC-Q exactive orbitrap HRMS, network pharmacology, and experiment verification

Feng Gao a,1, Tong Zhang a,1, Hao zhang a, Ziqi Dai a, Yuhao Gu a, Mingjun Lu a, Zijie Zhang a, Qi Zeng a, Bingxian Shang a, Shan Gao a, Nan Wang b, Bing Xu a,**, Haimin Lei

doi : 10.1016/j.jep.2022.115924

Volume 303, 1 March 2023, 115924

A network pharmacology approach and experimental validation to investigate the anticancer mechanism and potential active targets of ethanol extract of Wei-Tong-Xin against colorectal cancer through induction of apoptosis via PI3K/AKT signaling pathway

Fei Lin a, Guanglin Zhang b, Xihan Yang b, Mengshi Wang a, Ruixuan Wang b, Meiqi Wan b, Jinyu Wang b, Bo Wu b, Tingxu Yan b,**, Ying Jia

doi : 10.1016/j.jep.2022.115933

Volume 303, 1 March 2023, 115933

Neoline, fuziline, songorine and 10-OH mesaconitine are potential quality markers of Fuzi: In vitro and in vivo explorations as well as pharmacokinetics, efficacy and toxicity evaluations

Xiaocui Li a, Weiqing Hou a, Tingting Lin a, Jiadong Ni a, Huawei Qiu a, Yu Fu a, Zhongxiang Zhao a, Caihua Yang c, Na Li d, Hua Zhou e, Rong Zhang a, Zhongqiu Liu a, Ling Fu b,**, Lijun Zhu

doi : 10.1016/j.jep.2022.115879

Volume 303, 1 March 2023, 115879

The rise and fall of mandrake in medicineâ˜†

Guillermo Ben?tez a,*, Marco Leonti b, Barbara BÂ¨ock c, Simon Vulfsons d, Amots Dafni

doi : 10.1016/j.jep.2022.115874

Volume 303, 1 March 2023, 115874

Effect of Paeoniae Radix Rubra (Paeonia lactiflora Pall.) extract on mucin secretion, gene expression in human airway epithelial cells

Song-Yi Han 1, Soo-Kyoung Lim 1, Hojun Kim

doi : 10.1016/j.jep.2022.115959

Volume 303, 1 March 2023, 115959

Cytotoxicity, oral toxicity, genotoxicity, and mutagenicity evaluation of essential oil from Psidium glaziovianum Kiaersk leaves

WË†endeo Kennedy Costa a,*, Matheus Ferreira do Nascimento a, Â´Edipo Lucas Soares Barbosa a, Talita Giselly dos Santos Souza a, Cristiano Aparecido Chagas b, Thiago Henrique Napole?ao a, Maria Tereza dos Santos Correia a, FÂ´abio AndrÂ´e Brayner c, Alisson MacÂ´ario de Oliveira a, MÂ´arcia Vanusa da Silva

doi : 10.1016/j.jep.2022.115955

Volume 303, 1 March 2023, 115955

Anti-influenza properties of tiliroside isolated from Hibiscus mutabilis L.

Mengjie Xiao a,1, Tianbo Zhang a,2,1, Fei Cao b, Weihong Liang f,g, Yinhua Yang d, Tao Huang h, Yun-Sang Tang a, Bo Liu f,g, Xin Zhao e,**, Pang-Chui Shaw

doi : 10.1016/j.jep.2022.115918

Volume 303, 1 March 2023, 115918

Network pharmacology, molecular docking, and experimental pharmacology explored Ermiao wan protected against periodontitis via the PI3K/AKT and NF-ÎºB/MAPK signal pathways

Zhengxiang Xia a, Qin Li b, Zhongyan Tang

doi : 10.1016/j.jep.2022.115900

Volume 303, 1 March 2023, 115900

Isolation and identification of angiogenesis-promoting components in Huanglian Jiedu decoction using live cell bio-specific extraction

Fengyun Liao a, Dongmei He b, Cuiting Liu c, Chi Teng Vong a, Zhangfeng Zhong a,*, Yitao Wang

Volume 303, 1 March 2023, 115961

Studies on the key constituents and the related mechanisms of Clerodendranthus spicatus in the treatment of diabetes based on network pharmacology

Qirou Wang a, Nannan Li a, Yajie Wang a, Ruilin Li a, Yanan Jia a, Jingna Zhou a, Junyu Liu a, Min Zhang b,c, Pengwei Zhuang d, Chengwei He e, Haixia Chen

Volume 303, 1 March 2023, 115949

Shenqi granule upregulates CD2AP and Î±-actinin4 and activates autophagy through regulation of mTOR/ULK1 pathway in MPC5 cells

Lifeng Wei a,1, Jun Yong a,1, Xianwen Zhang a,1, Chunyan Ling b, Yansheng Wu a, Zheng Xu c, Hengzhou Zhang c, Xueqing Cao c, Lingli Sheng a, Quan Zhang a, Yiping Chen a,**, Lin Wang

Volume 303, 1 March 2023, 115942

Eugenia gracillima essential oil has pharmaceutical applications in pain and inflammation without toxic effects in mice

Joyce Bezerra Guedes a,*, Andreza Larissa do Nascimento a, WË†endeo Kennedy Costa a, Bruno Oliveira de Veras c, J?lio CÂ´esar Ribeiro de Oliveira Farias de Aguiar b, Daniela Maria do Amaral Ferraz Navarro b, Thiago Henrique Napole?ao a, MÂ´arcia Vanusa da Silva a, Alisson MacÂ´ario de Oliveira a, Maria Tereza dos Santos Correia

Volume 303, 1 March 2023, 115941

Buyang Huanwu decoction alleviates oxidative injury of cerebral ischemia-reperfusion through PKCÎµ/Nrf2 signaling pathway

Meijuan Yin a,1, Zhenyi Liu a,1, Jing Wang a,b, Weijuan Gao

Volume 303, 1 March 2023, 115953

Senna petersiana (Bolle) leaf extract modulates glycemic homeostasis and improves dysregulated enzyme activities in fructose-fed streptozotocin-induced diabetic rats

Kolawole A. Olofinsan a, Veronica F. Salau a, Ochuko L. Erukainure b, Md. Shahidul Islam

Volume 303, 1 March 2023, 115998

Exploring the potential of ginseng glycoprotein to improve learning and memory in mice via Notch signaling pathway and structural analysis using multi-information fusion based on liquid chromatography-mass spectrometry

Xiaoxue Fang a,c,1, Xiaoying Zhang b,1, Yegang Zhang a,c, Xun Zhang d, Mengyao Shan a,c, Shuguang Guan a,c, Zhidong Qiu a,c, Difu Zhu a,c,*, Haoming Luo

Volume 303, 1 March 2023, 115978

Glycyrrhizin mitigates acute lung injury by inhibiting the NLRP3 inflammasome in vitro and in vivo

JunMei Wang a, Chunxiu Ren b, WenHui Bi b, Wuliji Batu

Volume 303, 1 March 2023, 115948

Sini San ameliorates CCl4-induced liver fibrosis in mice by inhibiting AKT-mediated hepatocyte apoptosis

Meijie Jiang a, Chunmei Huang b, Qiong Wu b, Yong Su b, Xinming Wang b, Zihua Xuan a, Yunlai Wang a,c, Fan Xu a,c,*, Chaoliang Ge

Volume 303, 1 March 2023, 115965

Sheng-ji Hua-yu ointment ameliorates cutaneous wound healing in diabetes via up-regulating CCN1

Dan Yang a,1, Yi-mei Tan b,c,d,e,1, Ying Zhang a,1, Jian-kun Song b, Yue Luo b, Ying Luo a,f, Xiao-ya Fei b, Yi Ru a, Bin Li b,f, Jing-si Jiang b,**, Le Kuai

Volume 303, 1 March 2023, 115954

Isolation and identification of angiogenesis-promoting components in Huanglian Jiedu decoction using live cell bio-specific extraction

Fengyun Liao a, Dongmei He b, Cuiting Liu c, Chi Teng Vong a, Zhangfeng Zhong a,*, Yitao Wang

Volume 303, 1 March 2023, 115961

Studies on the key constituents and the related mechanisms of Clerodendranthus spicatus in the treatment of diabetes based on network pharmacology

Qirou Wang a, Nannan Li a, Yajie Wang a, Ruilin Li a, Yanan Jia a, Jingna Zhou a, Junyu Liu a, Min Zhang b,c, Pengwei Zhuang d, Chengwei He e, Haixia Chen

Volume 303, 1 March 2023, 115949

Shenqi granule upregulates CD2AP and Î±-actinin4 and activates autophagy through regulation of mTOR/ULK1 pathway in MPC5 cells

Lifeng Wei a,1, Jun Yong a,1, Xianwen Zhang a,1, Chunyan Ling b, Yansheng Wu a, Zheng Xu c, Hengzhou Zhang c, Xueqing Cao c, Lingli Sheng a, Quan Zhang a, Yiping Chen a,**, Lin Wang

Volume 303, 1 March 2023, 115942

Eugenia gracillima essential oil has pharmaceutical applications in pain and inflammation without toxic effects in mice

Volume 303, 1 March 2023, 115941

Buyang Huanwu decoction alleviates oxidative injury of cerebral ischemia-reperfusion through PKCÎµ/Nrf2 signaling pathway

Meijuan Yin a,1, Zhenyi Liu a,1, Jing Wang a,b, Weijuan Gao

Volume 303, 1 March 2023, 115953

Senna petersiana (Bolle) leaf extract modulates glycemic homeostasis and improves dysregulated enzyme activities in fructose-fed streptozotocin-induced diabetic rats

Kolawole A. Olofinsan a, Veronica F. Salau a, Ochuko L. Erukainure b, Md. Shahidul Islam

Volume 303, 1 March 2023, 115998

Exploring the potential of ginseng glycoprotein to improve learning and memory in mice via Notch signaling pathway and structural analysis using multi-information fusion based on liquid chromatography-mass spectrometry

Xiaoxue Fang a,c,1, Xiaoying Zhang b,1, Yegang Zhang a,c, Xun Zhang d, Mengyao Shan a,c, Shuguang Guan a,c, Zhidong Qiu a,c, Difu Zhu a,c,*, Haoming Luo

Volume 303, 1 March 2023, 115978

Glycyrrhizin mitigates acute lung injury by inhibiting the NLRP3 inflammasome in vitro and in vivo

JunMei Wang a, Chunxiu Ren b, WenHui Bi b, Wuliji Batu

Volume 303, 1 March 2023, 115948

Sini San ameliorates CCl4-induced liver fibrosis in mice by inhibiting AKT-mediated hepatocyte apoptosis

Meijie Jiang a, Chunmei Huang b, Qiong Wu b, Yong Su b, Xinming Wang b, Zihua Xuan a, Yunlai Wang a,c, Fan Xu a,c,*, Chaoliang Ge

Volume 303, 1 March 2023, 115965

Sheng-ji Hua-yu ointment ameliorates cutaneous wound healing in diabetes via up-regulating CCN1

Dan Yang a,1, Yi-mei Tan b,c,d,e,1, Ying Zhang a,1, Jian-kun Song b, Yue Luo b, Ying Luo a,f, Xiao-ya Fei b, Yi Ru a, Bin Li b,f, Jing-si Jiang b,**, Le Kuai

Volume 303, 1 March 2023, 115954

Isolation and identification of angiogenesis-promoting components in Huanglian Jiedu decoction using live cell bio-specific extraction

Fengyun Liao a, Dongmei He b, Cuiting Liu c, Chi Teng Vong a, Zhangfeng Zhong a,*, Yitao Wang

Volume 303, 1 March 2023, 115961

Studies on the key constituents and the related mechanisms of Clerodendranthus spicatus in the treatment of diabetes based on network pharmacology

Qirou Wang a, Nannan Li a, Yajie Wang a, Ruilin Li a, Yanan Jia a, Jingna Zhou a, Junyu Liu a, Min Zhang b,c, Pengwei Zhuang d, Chengwei He e, Haixia Chen

Volume 303, 1 March 2023, 115949

Shenqi granule upregulates CD2AP and Î±-actinin4 and activates autophagy through regulation of mTOR/ULK1 pathway in MPC5 cells

Lifeng Wei a,1, Jun Yong a,1, Xianwen Zhang a,1, Chunyan Ling b, Yansheng Wu a, Zheng Xu c, Hengzhou Zhang c, Xueqing Cao c, Lingli Sheng a, Quan Zhang a, Yiping Chen a,**, Lin Wang

Volume 303, 1 March 2023, 115942

Eugenia gracillima essential oil has pharmaceutical applications in pain and inflammation without toxic effects in mice

Volume 303, 1 March 2023, 115941

Buyang Huanwu decoction alleviates oxidative injury of cerebral ischemia-reperfusion through PKCÎµ/Nrf2 signaling pathway

Meijuan Yin a,1, Zhenyi Liu a,1, Jing Wang a,b, Weijuan Gao

Volume 303, 1 March 2023, 115953

Senna petersiana (Bolle) leaf extract modulates glycemic homeostasis and improves dysregulated enzyme activities in fructose-fed streptozotocin-induced diabetic rats

Kolawole A. Olofinsan a, Veronica F. Salau a, Ochuko L. Erukainure b, Md. Shahidul Islam

Volume 303, 1 March 2023, 115998

Exploring the potential of ginseng glycoprotein to improve learning and memory in mice via Notch signaling pathway and structural analysis using multi-information fusion based on liquid chromatography-mass spectrometry

Xiaoxue Fang a,c,1, Xiaoying Zhang b,1, Yegang Zhang a,c, Xun Zhang d, Mengyao Shan a,c, Shuguang Guan a,c, Zhidong Qiu a,c, Difu Zhu a,c,*, Haoming Luo

Volume 303, 1 March 2023, 115978

Glycyrrhizin mitigates acute lung injury by inhibiting the NLRP3 inflammasome in vitro and in vivo

JunMei Wang a, Chunxiu Ren b, WenHui Bi b, Wuliji Batu

Volume 303, 1 March 2023, 115948

Sini San ameliorates CCl4-induced liver fibrosis in mice by inhibiting AKT-mediated hepatocyte apoptosis

Meijie Jiang a, Chunmei Huang b, Qiong Wu b, Yong Su b, Xinming Wang b, Zihua Xuan a, Yunlai Wang a,c, Fan Xu a,c,*, Chaoliang Ge

Volume 303, 1 March 2023, 115965

Sheng-ji Hua-yu ointment ameliorates cutaneous wound healing in diabetes via up-regulating CCN1

Dan Yang a,1, Yi-mei Tan b,c,d,e,1, Ying Zhang a,1, Jian-kun Song b, Yue Luo b, Ying Luo a,f, Xiao-ya Fei b, Yi Ru a, Bin Li b,f, Jing-si Jiang b,**, Le Kuai

Volume 303, 1 March 2023, 115954

Isolation and identification of angiogenesis-promoting components in Huanglian Jiedu decoction using live cell bio-specific extraction

Fengyun Liao a, Dongmei He b, Cuiting Liu c, Chi Teng Vong a, Zhangfeng Zhong a,*, Yitao Wang

Volume 303, 1 March 2023, 115961

Studies on the key constituents and the related mechanisms of Clerodendranthus spicatus in the treatment of diabetes based on network pharmacology

Qirou Wang a, Nannan Li a, Yajie Wang a, Ruilin Li a, Yanan Jia a, Jingna Zhou a, Junyu Liu a, Min Zhang b,c, Pengwei Zhuang d, Chengwei He e, Haixia Chen

Volume 303, 1 March 2023, 115949

Shenqi granule upregulates CD2AP and Î±-actinin4 and activates autophagy through regulation of mTOR/ULK1 pathway in MPC5 cells

Lifeng Wei a,1, Jun Yong a,1, Xianwen Zhang a,1, Chunyan Ling b, Yansheng Wu a, Zheng Xu c, Hengzhou Zhang c, Xueqing Cao c, Lingli Sheng a, Quan Zhang a, Yiping Chen a,**, Lin Wang

Volume 303, 1 March 2023, 115942

Eugenia gracillima essential oil has pharmaceutical applications in pain and inflammation without toxic effects in mice

Volume 303, 1 March 2023, 115941

Buyang Huanwu decoction alleviates oxidative injury of cerebral ischemia-reperfusion through PKCÎµ/Nrf2 signaling pathway

Meijuan Yin a,1, Zhenyi Liu a,1, Jing Wang a,b, Weijuan Gao

Volume 303, 1 March 2023, 115953

Senna petersiana (Bolle) leaf extract modulates glycemic homeostasis and improves dysregulated enzyme activities in fructose-fed streptozotocin-induced diabetic rats

Kolawole A. Olofinsan a, Veronica F. Salau a, Ochuko L. Erukainure b, Md. Shahidul Islam

Volume 303, 1 March 2023, 115998

Exploring the potential of ginseng glycoprotein to improve learning and memory in mice via Notch signaling pathway and structural analysis using multi-information fusion based on liquid chromatography-mass spectrometry

Xiaoxue Fang a,c,1, Xiaoying Zhang b,1, Yegang Zhang a,c, Xun Zhang d, Mengyao Shan a,c, Shuguang Guan a,c, Zhidong Qiu a,c, Difu Zhu a,c,*, Haoming Luo

Volume 303, 1 March 2023, 115978

Glycyrrhizin mitigates acute lung injury by inhibiting the NLRP3 inflammasome in vitro and in vivo

JunMei Wang a, Chunxiu Ren b, WenHui Bi b, Wuliji Batu

Volume 303, 1 March 2023, 115948

Sini San ameliorates CCl4-induced liver fibrosis in mice by inhibiting AKT-mediated hepatocyte apoptosis

Meijie Jiang a, Chunmei Huang b, Qiong Wu b, Yong Su b, Xinming Wang b, Zihua Xuan a, Yunlai Wang a,c, Fan Xu a,c,*, Chaoliang Ge

Volume 303, 1 March 2023, 115965

Sheng-ji Hua-yu ointment ameliorates cutaneous wound healing in diabetes via up-regulating CCN1

Dan Yang a,1, Yi-mei Tan b,c,d,e,1, Ying Zhang a,1, Jian-kun Song b, Yue Luo b, Ying Luo a,f, Xiao-ya Fei b, Yi Ru a, Bin Li b,f, Jing-si Jiang b,**, Le Kuai

Volume 303, 1 March 2023, 115954

Aidi injection enhances the anti-tumor impact of doxorubicin in H22 tumor-containing mice

Yuan Lu a,b,1, Shuai Zhang b,1, Xiaoqin Zhu c, Kailiang Wang c, Yan He b, Chunhua Liu d, Jia Sun a, Jie Pan a, Lin Zheng a, Wen Liu b,c, Yongjun Li c,d, Yong Huang a,**, Ting Liu

doi : 10.1016/j.jep.2022.115968

Volume 303, 1 March 2023, 115968

Xianglian pill modulates gut microbial production of succinate and induces regulatory T cells to alleviate ulcerative colitis in rats

Chang-Shun Liu a,b,*, Yin-Xia Hu c, Zhen-Ye Luo a,b, Chuan-Wei Qiu a,b, Xiang-Hua Deng a,b, Fei-Long Chen

doi : 10.1016/j.jep.2022.116007

Volume 303, 1 March 2023, 116007

Mechanism of Jinzhen Oral Liquid against influenza-induced lung injury based on metabonomics and gut microbiome

Jian Feng a,b,c,1, Xia Gao b,c,1, Xialin Chen b,c,**, Xiaoyu Tong b,c, Mengyu Qian b,c, Huifang Gao b,c, Jiajia Wang b,c, Shanli Wang b,c, Chenghao Fei b,c, Liang Cao b,c, Zhenzhong Wang a,b,c,***, Wei Xiao

doi : 10.1016/j.jep.2022.115977

Volume 303, 1 March 2023, 115977

Deep-fried Atractylodes lancea rhizome alleviates spleen deficiency diarrheaâ€“induced short-chain fatty acid metabolic disorder in mice by remodeling the intestinal flora

Chunlian Liu a,1, Chengcheng Song a,1, Yan Wang a, Yangxin Xiao a, Zhongshi Zhou a,b, Guosheng Cao a,b, Xiongjie Sun a,b,**, Yanju Liu

doi : 10.1016/j.jep.2022.115967

Volume 303, 1 March 2023, 115967

Antioxidant, anti-inflammatory and analgesic activity of Mimosa acutistipula (Mart.) Benth

Layza Fernanda Gomes Bezerra, Ana Paula Santâ€™Anna da Silva, Rebeca Xavier da Cunha, Jo?ao Ricardhis Saturnino de Oliveira, Mateus Domingues de Barros, Vycttor Mateus de Melo Alves da Silva, Vera L?cia de Menezes Lima

doi : 10.1016/j.jep.2022.115964

Volume 303, 1 March 2023, 115964

Phytochemical analysis, anti-inflammatory, antioxidant activity of Calotropis gigantea and its therapeutic applications

Sreewardhini Sivapalan a, Sankari Dharmalingam a,*, Vijayalakshmi Venkatesan b, Mangalagowri Angappan c, Veeramuthu Ashokkumar

doi : 10.1016/j.jep.2022.115963

Volume 303, 1 March 2023, 115963

Anti-hyperglycemic potential and chemical constituents of Aristolochia triangularis Cham. leaves âˆ’ A medicinal species native to Brazilian forests

FlÂ´avio Henrique Souza de Ara?jo a, ClÂ´audio Rodrigo Nogueira b,*, Virginia Demarchi Kappel Trichez a, Zaira da Rosa Guterres c, Luciano da Silva Pinto d, Suzana Queiroz Velter b, Guilherme Antonio Mantovani Ferreira b, Marcos Batista Machado e, Kidney de Oliveira Gomes Neves e, Maria do Carmo Vieira f, Claudia Andrea Lima Cardoso g, Silvia Cristina Heredia-Vieira h, Kelly Mari Pires de Oliveira i, Raul Cremonize Piva g, Silvia Aparecida Oesterreich a

doi : 10.1016/j.jep.2022.115991

Volume 303, 1 March 2023, 115991

Tingli Dazao Decoction pretreatment ameliorates mitochondrial damage induced by oxidative stress in cardiomyocytes

Huihui Chen a,b, Yue Zhu a, Xiaoping Zhao c,**, Zhenzhong Yang

doi : 10.1016/j.jep.2022.115987

Volume 303, 1 March 2023, 115987

Antiviral activity of two Acanthospermum species against herpes simplex virus 1

Guadalupe Cantero-GonzÂ´alez a,1, Nelson Alvarenga b,1, Marcos M. Florent?n-Pav?a a, Pamela Gonzalez-Maldonado a, Pablo H. Sotelo

doi : 10.1016/j.jep.2022.115958

Volume 303, 1 March 2023, 115958

Influence of pyrrolizidine alkaloids depletion upon the biological activity of Symphytum officinale L. extracts

Adriana Trifan a, Monika E. CzerwiÂ´nska b,c,*, Gokhan Zengin d, Nils Esslinger e, Andreas Grubelnik e, Evelyn Wolfram f, Krystyna Skalicka-WoÂ´zniak g, Simon Vlad Luca

doi : 10.1016/j.jep.2022.116010

Volume 303, 1 March 2023, 116010

Aniba canelilla (Kunth) Mez essential oil and its primary constituent, 1-nitro-2-phenylethane, inhibits acetylcholinesterase and reverse memory impairment in rodents

Daniele L. de Campos a,b, Let?cia Y. Queiroz a,b, EnÂ´eas A. Fontes-Junior a, Bruno G. Pinheiro c, Joyce Kelly R. da Silva d, Cristiane Socorro F. Maia a,b, JosÂ´e Guilherme S. Maia

doi : 10.1016/j.jep.2022.116036

Volume 303, 1 March 2023, 116036

Berbamine dihydrochloride suppresses the progression of colorectal cancer via RTKs/Akt axis

Lu Liu a,b, Dan Liang b, Qiao Zheng b, Maoyuan Zhao b, RuiTing Lv c, Jianyuan Tang b,**, Nianzhi Chen

doi : 10.1016/j.jep.2022.116025

Volume 303, 1 March 2023, 116025

Shen-Qi-Jiang-Tang granule ameliorates diabetic nephropathy via modulating tumor necrosis factor signaling pathway

doi : 10.1016/j.jep.2022.116031

Volume 303, 1 March 2023, 116031

Integrated miRNA and mRNA omics reveal dioscin suppresses migration and invasion via MEK/ERK and JNK signaling pathways in human endometrial carcinoma in vivo and in vitro

Xiao-Li Li a, Xiu-Xiu Zhang a, Run-Hui Ma a,b, Zhi-Jing Ni a,b, Kiran Thakur a,b, Carlos L. Cespedes-Acu?na c, Jian-Guo Zhang a,b, Zhao-Jun Wei

doi : 10.1016/j.jep.2022.116027

Volume 303, 1 March 2023, 116027

Huangqin decoction mitigates hepatic inflammation in high-fat diet-challenged rats by inhibiting TLR4/NF-ÎºB/NLRP3 pathway

Bao-Fei Yan a,b,1, Yun Wang c,1, Wen-Bo Wang d,1, Xiao-Jun Ding e, Bin Wei f, Sheng-Jin Liu b, Ting-Ming Fu b, Ling Chen a, Jing-Zheng Zhang a, Jia Liu a,**, Xian Zheng

doi : 10.1016/j.jep.2022.115999

Volume 303, 1 March 2023, 115999

Tibetan medicine Si-Wei-Qiang-Wei Powder ameliorates cholecystitis via inhibiting the production of pro-inflammatory cytokines and regulating the MAPK signaling pathway

Zhe Zheng a,1, Hui Xiong a,1, Zhongqiu Zhao b,c, Keli Zhou d, Miao Fu a, Xinqiao Liu a,*, Zhinan Mei

doi : 10.1016/j.jep.2022.116026

Volume 303, 1 March 2023, 116026

Effect of CYP3A inducer/inhibitor and licorice on hepatotoxicity and in vivo metabolism of main alkaloids of Euodiae Fructus based on UPLC-Q-Exactive-MS

Kun Ren a, Ruijie Wang a, Shinuo Fang a, Shumeng Ren a, Huiming Hua a, Dongmei Wang b,**, Yingni Pan a,***, Xiaoqiu Liu

doi : 10.1016/j.jep.2022.116005

Volume 303, 1 March 2023, 116005

Comparative pharmacokinetics of seven bioactive components after oral administration of crude and processed Qixue Shuangbu Prescription in chronic heart failure rats by microdialysis combined with UPLC-MS/MS

Linwei Chen a,b, Nina Wei a, Yong Jiang a, Chengye Yuan a,b, Luwei Xu a,b, Jindong Li c, Min Kong c,*, Yan Chen a,b,**, Qin Wang

doi : 10.1016/j.jep.2022.116035

Volume 303, 1 March 2023, 116035

Investigation on property differences of ginseng and American ginseng by spatial metabolomics of neurochemicals with desorption electrospray ionization mass spectrometry imaging

Xin Huang a,*, Rui Wang a, Yikai Wang a, Changbao Chen a,**, Shuying Liu

doi : 10.1016/j.jep.2022.116006

Volume 303, 1 March 2023, 116006

Analgesic and anti-inflammatory potential of ethanolic extract from Serjania erecta leaves

Laura Priscila Toledo Bernal a, Maicon Matos Leit?ao a,b, Joyce Alencar Santos Radai a, Claudia Andrea Lima Cardoso c, Joyce dos Santos Lencina d, Thiago Leite Fraga b, Arielle Cristina Arena e, Saulo Euclides Silva-Filho d, CË†andida Aparecida Leite Kassuya

doi : 10.1016/j.jep.2022.116019

Volume 303, 1 March 2023, 116019

How efficacious are traditional Chinese medicine injections in treating angina pectoris? A network meta-analysis of randomized controlled trials

Yongliang Jia a,b,*,1, Guoying Gao b,1, Siu-wai Leung

doi : 10.1016/j.jep.2022.115996

Volume 303, 1 March 2023, 115996

The combined analgesic, sedative, and anti-gastric cancer mechanisms of Tinospora sagittata var. yunnanensis (S. Y. Hu) H. S. Lo based on integrated ethnopharmacological data

Qian-Qian Wang a,c,1, Qin-Rong Sun a,c,1, Xin-ye Ji c, Yun Tang d, Ke Zhang c, Xiao-Qin Wang c, Hong-Rui Li b, Xiang-Zhong Huang b,**, Bo Zhang

doi : 10.1016/j.jep.2022.115990

Volume 303, 1 March 2023, 115990

Compositions analysis and insecticidal activity of Aconitum polycarpum Chang ex W.T.Wang petroleum ether fractions and essential oils

Ke Xu a, Ziyu Song a, Junqi Liu a, Liu Yang a, Guoqing Sun a, Lijie Lei a, Shuai Huang a, Feng Gao a, Lin Chen a,*, Xianli Zhou

doi : 10.1016/j.jep.2022.115989

Volume 303, 1 March 2023, 115989

Revealing the most effective anticonvulsant part of Malvaviscus arboreus Dill. Ex Cav. and its acute and sub-acute toxicity

Maxwell Blesdel Adassi a, Gwladys Temkou Ngoupaye b,*, Francis Bray Yassi c, Aurelien Fossueh Foutsop b, Tatiana Diebo Kom a, Elisabeth Ngo Bum

doi : 10.1016/j.jep.2022.115995

Volume 303, 1 March 2023, 115995

Ginsenoside Rb1 protects against diabetes-associated metabolic disorders in Kkay mice by reshaping gut microbiota and fecal metabolic profiles

Rongrong Zhou a,1, Dan He c,d,1, Haichao Zhang c,d, Jing Xie c,d, Shuihan Zhang c, Xuefei Tian d, Hongliang Zeng c,***, Yuhui Qin c,d,**, Luqi Huang

doi : 10.1016/j.jep.2022.115997

Volume 303, 1 March 2023, 115997

Alternanthera brasiliana L. extract alleviates carbon tetrachloride-induced liver injury and fibrotic changes in mice: Role of matrix metalloproteinases and TGF-Î²/Smad axis

Vinay M. Paliwal a, Sourav Kundu a, Uttam Kulhari a, Aishwarya Jala b, Sharmeen Ishteyaque c, Roshan M. Borkar b, Madhav Nilakanth Mugale c, Upadhyayula Suryanarayana Murty a, Bidya Dhar Sahu

doi : 10.1016/j.jep.2022.115992

Volume 303, 1 March 2023, 115992

EXPLORING the prophylactic potential of Azadirachta indica leaf extract against dyslipidemia

Hafiza Anam Asghar a, Qamar Abbas Syed a,*, Rizwan Shukat a, Beenish Israr b

doi : 10.1016/j.jep.2022.116008

Volume 303, 1 March 2023, 116008

Sinomenine attenuated dextran sulfate sodium-induced inflammatory responses by promoting 14-3-3Î¸ protein and inhibiting NF-ÎºB signaling

Yan Zhou a,b, Shuai Chen b, Yi Dai b, Liunan Wu c, Ming Jin c, Jie Zhao a,b, Yuan Li c,**, Liming Tang

doi : 10.1016/j.jep.2022.116037

Volume 303, 1 March 2023, 116037

The extract from Hyssopus cuspidatus Boriss. Prevents bronchial airway remodeling by inhibiting mouse bronchial wall thickening and hASMC proliferation and migration

Xiaocui Cai a, Yan Mao a, Xiaoli Shen b, Haifang Li b,**, Jinhua He a,*, Mingjun Zhang

doi : 10.1016/j.jep.2022.116047

Volume 303, 1 March 2023, 116047

Clinacanthus nutans aqueous leaves extract exerts anti-allergic activity in preclinical anaphylactic models via alternative IgG pathway

Audrey Siew Foong Kow a,e, Leng Wei Khoo b, Ji Wei Tan a,c, Faridah Abas b,d, Ming-Tatt Lee e,f,g, Daud Ahmad Israf a, Khozirah Shaari d, Chau Ling Tham

doi : 10.1016/j.jep.2022.116003

Volume 303, 1 March 2023, 116003

Exploring the anti-inflammatory potential of Colocasia esculenta root extract in in-vitro and in-vivo models of inflammation

Momita Rani Baro , Manas Das *, Anuradha Kalita, Bhabajyoti Das, Kishore Sarma

doi : 10.1016/j.jep.2022.116021

Volume 303, 1 March 2023, 116021

Inhibition of SLC7A11-GPX4 signal pathway is involved in aconitine-induced ferroptosis in vivo and in vitro

Qiuju Li a, Fu Peng b, Xiaoyu Yan a, Yan Chen a, Jie Zhou a, Shuangyue Wu a, Wanyanhan Jiang a, Xuhui Jin c, Jie Liang a, Cheng Peng a,**, Xiaoqi Pan

doi : 10.1016/j.jep.2022.116029

Volume 303, 1 March 2023, 116029

Moquiniastrum polymorphum subsp. polymorphum extract inhibits the proliferation of an activated hepatic stellate cell line (GRX) by regulating the p27 pathway to generate cell cycle arrest

Matheus Scherer Bastos a,b,*, Rafaela Mallmann Saalfeld a, Bruna Pasqualotto Costa a, Maria Claudia Garcia a, Krist Helen Antunes c, KÂ´etlin Fernanda Rodrigues a, Denizar Melo a, Eliane Romanato SantarÂ´em b, Jarbas Rodrigues de Oliveira

doi : 10.1016/j.jep.2022.116056

Volume 303, 1 March 2023, 116056

New substances of Equisetum hyemale L. extracts and their in vivo antitumoral effect against oral squamous cell carcinoma

Lucas Nicolau de Queiroz a, Anna Carolina Carvalho Da Fonseca b, Guilherme Freimann Wermelinger c, Diego Polo Dutra da Silva c, Aislan Cristina Rheder Fagundes Pascoal c, Alexandra Christine Helena Frankland Sawaya d, Elan Cardozo Paes de Almeida c, Bruno Sergio do Amaral e, Davyson de Lima Moreira f, Bruno Kaufmann Robbs

doi : 10.1016/j.jep.2022.116043

Volume 303, 1 March 2023, 116043

Exploring the effect of Weifuchun capsule on the toll-like receptor pathway mediated HES6 and immune regulation against chronic atrophic gastritis

Boyang Wang a,1, Wuai Zhou a,1, Huan Zhang b,1, Weihua Wang c, Bo Zhang b,**, Shao Li a

doi : 10.1016/j.jep.2022.115930

Volume 303, 1 March 2023, 115930

Fuzheng Xiaoai Decoction 1 ameliorated cancer cachexia-induced muscle atrophy via Akt-mTOR pathway

Qiao-Qiao Cheng a, Shi-Long Mao a, Li-Na Yang a, Li Chen a, Jin-Zhi Zhu a, Xuan Liu b,**, An-Ji Hou a,***, Rong-Rong Zhang

doi : 10.1016/j.jep.2022.115944

Volume 303, 1 March 2023, 115944

Effects and mechanisms of Xiaochaihu Tang against liver fibrosis: An integration of network pharmacology, molecular docking and experimental validation

Shou-Jia Wang a,b,1, Wen Ye a,b,1, Wan-Yi Li c,1, Wen Tian a,b, Meng Zhang a,b, Yang Sun a,b, Ying-Da Feng a,b, Chen-Xu Liu a,b, Shao-Yuan Liu a,b, Wei Cao a,d, Jing-Ru Meng a,b,**, Xiao-Qiang Li a

doi : 10.1016/j.jep.2022.116053

Volume 303, 1 March 2023, 116053

Isoliquiritigenin from licorice flavonoids attenuates NLRP3-mediated pyroptosis by SIRT6 in vascular endothelial cells

Jianyu He a,1, Ying Deng a,1, Lingxuan Ren a, Zhen Jin a, Jianjun Yang a, Feng Yao a, Yizhen Liu a, Zihan Zheng a, Danli Chen a, Bo Wang a, Yirong Zhang b, Guanjun Nan c, Weirong Wang b,*, Rong Lin

doi : 10.1016/j.jep.2022.115952

Volume 303, 1 March 2023, 115952

Corrigendum to â€œXinfeng capsule inhibits inflammation and oxidative stress in rheumatoid arthritis by up-regulating LINC00638 and activating Nrf2/HO-1 pathwayâ€� [J. Ethnopharmacol. 301 (2023) 115839]

Yanqiu Sun a,c, Jian Liu a,c,*, Ling Xin b,c, Jianting Wen a,c, Qin Zhou a,c, Xiaolu Chen a,c, Xiang Ding a,c, Xianheng Zhang

doi : 10.1016/j.jep.2022.115925

Volume 303, 1 March 2023, 115925

Corrigendum to â€œNetwork pharmacology-based mechanism prediction and pharmacological validation of Xiaoyan Lidan formula on attenuating alpha-naphthylisothiocyanate induced cholestatic hepatic injury in ratsâ€� [J. Ethnopharmacol. 270 (2021) 113816]

Meiqi Wang, Fangle Liu, Yufeng Yao, Qiuyu Zhang, Zenghui Lu, Runjing Zhang, Changhui Liu, Chaozhan Lin **, Chenchen Zhu

doi : 10.1016/j.jep.2022.115976

Volume 303, 1 March 2023, 115976

Corrigendum to â€œIn vivo and in vitro protective effects of the Wuzi Yanzong pill against experimental spermatogenesis disorder by promoting germ cell proliferation and suppressing apoptosisâ€� [J. Ethnopharmacol. 280 (2021) 114443]

Wang-qiang Chen a,1, Bin Wang b,1, Cai-fei Ding a,1, Ling-yi Wan a, Hui-min Hu a, Bo-dong Lv c,**, Jian-xiong Ma

doi : 10.1016/j.jep.2022.116039

Volume 303, 1 March 2023, 116039

Corrigendum to â€œKunling Wan improves oocyte quality by regulating the PKC/Keap1/Nrf2 pathway to inhibit oxidative damage caused by repeated controlled ovarian hyperstimulationâ€� [J. Ethnopharmacol. 301 (2023) 115777]

Fengli Guan 1, Shuancheng Zhang 1, Lijie Fan, Ying Sun, Yucong Ma, Can Cao, Yu Zhang, Ming He **, Huilan Du

doi : 10.1016/j.jep.2022.116045

Volume 303, 1 March 2023, 116045