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Ephedrae herba: A comprehensive review of its traditional uses, phytochemistry, pharmacology, and toxicology
Qingge Zheng a,1, Xiangyu Mu b,1, Shaobin Pan a, Ruqiao Luan c,*, Pan Zhao
doi : 10.1016/j.jep.2023.116153
Volume 307, 10 May 2023, 116153
Research progress of quality control for the seed of Ziziphus jujuba var. spinosa (Bunge) Hu ex H.F. Chow (Suan-Zao-Ren) and its proprietary Chinese medicines
Li Gong a,b, Jun-bo Xie c, Yi Luo d, Zi-dong Qiu a,***, Jin-rui Liu b, Nan-ju Mei b, Ze-yan Chen a, Feng-ling Wang b, Yun Huang e, Juan Guo a, Guang-hong Cui a, Yan-qing Zhang b,**, Chang-jiang-sheng Lai
doi : 10.1016/j.jep.2023.116204
Volume 307, 10 May 2023, 116204
Characteristics of Chinese herbal medicine mouthwash clinical studies: A bibliometric and content analysis
Fen Zhou a,*, Xiaoying Mu a,1, Zhaoyu Li b, Manjie Guo a,1, Jianan Wang a,1, Pengyi Long a,1, Yujia Wan a,1, Ting Yuan a, Yunpeng Lv
doi : 10.1016/j.jep.2023.116210
Volume 307, 10 May 2023, 116210
A review of hemostatic chemical components and their mechanisms in traditional Chinese medicine and ethnic medicine
Kailang Mu, Yuchen Liu *, Gang Liu **, Fei Ran, Lingli Zhou, Yutong Wu, Leqiang Peng, Minghui Shao, Changju Li, Yongping Zhang
doi : 10.1016/j.jep.2023.116200
Volume 307, 10 May 2023, 116200
Chemical constituents, pharmacological effects, toxicology, processing and compatibility of Fuzi (lateral root of Aconitum carmichaelii Debx): A review
Guannan He, Xiaoxin Wang, Weiran Liu, Yuling Li, Yumeng Shao, Weidong Liu, Xiaodong Liang *, Xia Bao
doi : 10.1016/j.jep.2023.116160
Volume 307, 10 May 2023, 116160
Traditional Chinese medicine decoctions and Chinese patent medicines for the treatment of depression: Efficacies and mechanisms
Wei Zhuang a,1, Shao-Li Liu b,1, Sheng-Yan Xi c,1, Ying-Nan Feng a, Ke Wang a, Teliebald Abduwali a, Ping Liu d, Xiao-Jiang Zhou d, Lan Zhang a,*, Xian-Zhe Dong
doi : 10.1016/j.jep.2023.116272
Volume 307, 10 May 2023, 116272
Herb–drug interactions between Panax notoginseng or its biologically active compounds and therapeutic drugs: A comprehensive pharmacodynamic and pharmacokinetic review
Yujuan Xie , Changhong Wang
doi : 10.1016/j.jep.2023.116156
Volume 307, 10 May 2023, 116156
Advances in traditional Chinese medicine for the treatment of chronic obstructive pulmonary disease
Xia Cao a,b,c,1, Yi Wang a,b,1, Ying Chen a,b,c, Mantong Zhao a,b,c, Lanyuan Liang a,b,c, Mengru Yang a,b,c, Jianhua Li a,b,c, Mingming Peng a,b,c, Wei Li a,b,c, Yiming Yue a,b,c, Han Zhang a,b,d, Chuanqiu Li a,b,c, Zunpeng Shu
doi : 10.1016/j.jep.2023.116229
Volume 307, 10 May 2023, 116229
Curative anti-typhoid effect of Detarium microcarpum Guill. & Perr. (Leguminosae) hydroethanolic extract root bark based-on in vivo and molecular docking analyses
Michel Arnaud Mbock a,b,c,d, Raceline Gounoue Kamkumo b,c,*, Rohit Shukla e, William Feudjou Fouatio f, Patrick Val`ere Tsouh Fokou c,g, Florence Ngueguim Tsofack b, Clarice Djouwoug Noussi b, Rodrigue Fifen b, Augustin Ephrem Nkengfack f, Tiratha Raj Singh e, Bruno Lenta Ndjakou h, Norbert Sewald i, Fabrice Fekam Boyom c, Jean Justin Essia Ngang a, Onana Boyomo a, Theophile Dimo
doi : 10.1016/j.jep.2023.116209
Volume 307, 10 May 2023, 116209
Long-term oral administration of Asarum heterotropoides f. mandshuricum (Maxim.) Kitag. decoction and its aristolochic acid analogs do not cause renal toxicity in mice
Meiting Liu a,b,1, Lianmei Wang a,1, Shasha Qin a, Yong Zhao a, Suyan Liu a, Yan Yi a, Chunying Li a, Jingzhuo Tian a, Chenyue Liu a, Jing Meng a, Yuan Wang a, Yushi Zhang a, Fang Wang a, Chen Pan a, Jiayin Han a, Xuan Tang a, Liping Wang a, Aihua Liang
doi : 10.1016/j.jep.2023.116202
Volume 307, 10 May 2023, 116202
Tripterygium wilfordii Hook F combination therapy with methotrexate for rheumatoid arthritis: An updated meta-analysis
Yijun Luo 1, Xiaoxiao Hou 1, Anran Xi 1, Mengxian Luo , Keer Wang , Zhenghao Xu
doi : 10.1016/j.jep.2023.116211
Volume 307, 10 May 2023, 116211
Gastroprotective action of the extract of Corydalis yanhusuo in Helicobacter pylori infection and its bioactive component, dehydrocorydaline
Hao Wu a,1, Qingyue Sun b,1, Huirong Dong a, Jiasen Qiao b, Ying lin a, Chen Yu a,**, Yanni Li
doi : 10.1016/j.jep.2023.116173
Volume 307, 10 May 2023, 116173
Qingyihuaji Formula promotes apoptosis and autophagy through inhibition of MAPK/ERK and PI3K/Akt/mTOR signaling pathway on pancreatic cancer in vivo and in vitro
Xiang Qian a,1, Qian-Yu Bi a,1, Zeng-Na Wang a,1, Fang Han b, Lu-Ming Liu c, Li-Bin Song c, Chang-Yu Li a, Ai-Qin Zhang b,**, Xu-Ming Ji
doi : 10.1016/j.jep.2023.116198
Volume 307, 10 May 2023, 116198
Chemical characterization of the polyphenolic rich fraction of Thunbergia erecta and its therapeutic potential against doxorubicin and cyclophosphamide-induced cognitive impairment in rats
Mariam I. Gamal El-Din a, Mina Y. George b,**, Fadia S. Youssef
doi : 10.1016/j.jep.2023.116213
Volume 307, 10 May 2023, 116213
Therapeutic effects and mechanisms of Ku-Gan formula on atopic dermatitis: A pilot clinical study and modular pharmacology analysis with animal validation
Xin Ma a,b,1, Le Kuai a,c,1, Jiankun Song b,1, Ying Luo a,c, Yi Ru a,c, Mingxia Wang b, Chunjie Gao b, Wencheng Jiang b, Yeqiang Liu b, Yun Bai b,**, Bin Li
doi : 10.1016/j.jep.2023.116194
Volume 307, 10 May 2023, 116194
Exploring the effect of Er miao San-containing serum on macrophage polarization through miR-33/NLRP3 pathway
Min Liu a,c,d,1, Jin Wang a,c,d,1, Simeng Chen a,c,d,1, Xiangwen Meng a,c,d, Zhiluo Cheng a,c,d, Jiayu Wang a,c,d, Yanan Tan a,c,d, Wenrui Su a,c,d, Zhiyuan Lu a,c,d, Min Zhang b,2,**, Xiaoyi Jia
doi : 10.1016/j.jep.2023.116178
Volume 307, 10 May 2023, 116178
Protective effects of flavonoids in Coreopsis tinctoria Nutt. in a mouse model of type 2 diabetes
Pei Ma a,b,1, Fan Yu a,b,1, Yi Zhong a,b, Lijia Xu a,b,*, Peigen Xiao
doi : 10.1016/j.jep.2023.116214
Volume 307, 10 May 2023, 116214
Anti-rheumatoid arthritis potential of Rhododendron molle G. Don leaf extract in adjuvant induced arthritis rats
Yuqiang Luo , Yu Shen , Luye Zong , Jiankun Xie , Liangfang Dai **, Xiangdong Luo
doi : 10.1016/j.jep.2023.116175
Volume 307, 10 May 2023, 116175
Immunomodulatory effects and mechanisms of Tiepishihu Xiyangshen granules on cyclophosphamide induced immuno-suppression via TLR4/MAPKs and PI3K/AKT/FOXO3a signal pathways
Nan Hu a, Yue Qu b, Ting-yu Liu a, Yue Zhou c, Chang Liu c, Jin-hui Wang c, Bao-feng Yang a,c,**, Chun-li Li
doi : 10.1016/j.jep.2023.116192
Volume 307, 10 May 2023, 116192
Qidan Tiaozhi capsule attenuates metabolic syndrome via activating AMPK/PINK1-Parkin-mediated mitophagy
Zuqing Su a,b,c,1, Hongxia Li a,b,1, Zeting Ye a,b,1, Ying Zhu a,b,c, Bing Feng a,b,c, Lipeng Tang a,b,c, Guangjuan Zheng
doi : 10.1016/j.jep.2022.116091
Volume 307, 10 May 2023, 116091
A comprehensive perspective on the disposition, metabolism, and pharmacokinetics of representative multi-components of Dengzhan Shengmai in rats with chronic cerebral hypoperfusion after oral administration
Congyu Ma 1, Ning Sheng 1, Yuanyuan Li 1, Hao Zheng , Zhe Wang , Jinlan Zhang
doi : 10.1016/j.jep.2023.116212
Volume 307, 10 May 2023, 116212
Taohong Siwu Decoction enhances human bone marrow mesenchymal stem cells proliferation, migration and osteogenic differentiation via VEGF-FAK signaling in vitro
Xiaolong Lu a,1,*, Juan Li b,1, Biao Zhou c,d,1, Xuedi Lu b, Wei Li b, Jian Ouyang
doi : 10.1016/j.jep.2023.116203
Volume 307, 10 May 2023, 116203
Effect of Guizhi Fuling Wan in primary dysmenorrhea: A randomized controlled trial
Yanan Luo a,1, Ping Mao a,1, Peipei Chen a, Chenjie Li b, Xianyun Fu a,*, Mingyan Zhuang
doi : 10.1016/j.jep.2023.116247
Volume 307, 10 May 2023, 116247
The total iridoid glycoside extract of Lamiophlomis rotata Kudo induces M2 macrophage polarization to accelerate wound healing by RAS/ p38 MAPK/NF-κB pathway
Lei Lei a, Guoguo Wan a, Xiaoyu Geng a, Jianguo Sun a, Yi Zhang b, Jianwei Wang a, Congwen Yang a, Zheng Pan
doi : 10.1016/j.jep.2023.116193
Volume 307, 10 May 2023, 116193
Verbenalin attenuates hepatic damage and mitochondrial dysfunction in alcohol-associated steatohepatitis by regulating MDMX/PPARα-mediated ferroptosis
Jiahui Dong a, Changlin Du a,1, Chuanting Xu a, Qi Wang a, Zhonghao Wang a, Qian Zhu a, Xiongwen Lv a,c, Lei Zhang a,c, Jun Li a, Cheng Huang a, Hua Wang a,b,**, Taotao Ma
doi : 10.1016/j.jep.2023.116227
Volume 307, 10 May 2023, 116227
A novel type lavandulyl flavonoid from Sophora flavescens as potential anti-hepatic injury agent that inhibit TLR2/NF-κB signaling pathway
Yan Lin a,b,c,d,1, Xing-Jun Chen a,b,c,d,1, Jing-Jing Li a,b,c,d, Lei He a,b,c,d, Ya-Ru Yang a,b,c, , Fei Zhong a,b,c,d, Ming-Hui He a,b,c,d, Yi-Tong Shen a,b,c,d, Bo Tu a,b,c,d,***, Xu Zhang a,b,c, d,**, Zhu Zeng
doi : 10.1016/j.jep.2023.116163
Volume 307, 10 May 2023, 116163
Scutellaria incarnata Vent. root extract and isolated phenylethanoid glycosides are neuroprotective against C2-ceramide toxicity
Carlos A. V´asquez-Londo?no a,*, Melanie-Jayne R. Howes b, Geison M. Costa c, Gonzalo Arboleda d, Maritza A. Rojas-Cardozo
doi : 10.1016/j.jep.2023.116218
Volume 307, 10 May 2023, 116218
Echinacea purpurea (L.) Moench extract suppresses inflammation by inhibition of C3a/C3aR signaling pathway in TNBS-induced ulcerative colitis rats
Daxing Gu a, Huiting Wang a, Mingen Yan a, Yaoxing Li a, Shijing Yang a, Dayou Shi a,b,c, Shining Guo a,b,c, Li Wu a,b,c, Cui Liu
doi : 10.1016/j.jep.2023.116221
Volume 307, 10 May 2023, 116221
Hypoglycemic effect of the dry leaf extract of Myrcia multiflora in streptozotocin-induced diabetic mice
doi : 10.1016/j.jep.2023.116241
Volume 307, 10 May 2023, 116241
Anti-inflammatory role of Artemisia argyi methanol extract by targeting the caspase-11 non-canonical inflammasome in macrophages
doi : 10.1016/j.jep.2023.116231
Volume 307, 10 May 2023, 116231
β-Hydroxybutyric acid upregulated by Suhuang antitussive capsule ameliorates cough variant asthma through GSK3β/AMPK-Nrf2 signal axis
doi : 10.1016/j.jep.2022.116013
Volume 307, 10 May 2023, 116013
Elsholtzia bodinieri Vaniot ameliorated acute lung injury in mice by regulating pyroptosis, inflammation, oxidative stress and macrophage polarization
doi : 10.1016/j.jep.2023.116232
Volume 307, 10 May 2023, 116232
Pathway network-based quantitative modeling of the time-dependent and dose-response anti-inflammatory effect of Reduning Injection
doi : 10.1016/j.jep.2023.116216
Volume 307, 10 May 2023, 116216
Effect of maca (Lepidium meyenii) extract on non-obstructive azoospermia in male mice
doi : 10.1016/j.jep.2023.116228
Volume 307, 10 May 2023, 116228
Yishen Tongluo formula alleviates diabetic kidney disease through regulating Sirt6/TGF-β1/Smad2/3 pathway and promoting degradation of TGF-β1
doi : 10.1016/j.jep.2023.116243
Volume 307, 10 May 2023, 116243
Traditional Chinese medicines (TCMs) with varied meridians (Gui-Jing) differentially alleviate the adverse impact of Coptis chinensis on gut microbiota
doi : 10.1016/j.jep.2023.116256
Volume 307, 10 May 2023, 116256
Bioactive compounds from four Indian medicinal plants have different potency to induce sex reversal in Nile tilapia: A chromatographic, molecular docking and in silico analysis
doi : 10.1016/j.jep.2023.116263
Volume 307, 10 May 2023, 116263
Yi-Shen-Hua-Shi granule ameliorates diabetic kidney disease by the “gut-kidney axis�
doi : 10.1016/j.jep.2023.116257
Volume 307, 10 May 2023, 116257
Hyperoside prevents high-fat diet-induced obesity by increasing white fat browning and lipophagy via CDK6-TFEB pathway
doi : 10.1016/j.jep.2023.116259
Volume 307, 10 May 2023, 116259
Jinfeng pills ameliorate premature ovarian insufficiency induced by cyclophosphamide in rats and correlate to modulating IL-17A/IL-6 axis and MEK/ERK signals
doi : 10.1016/j.jep.2023.116242
Volume 307, 10 May 2023, 116242
Fermented Gynochthodes officinalis (F.C.How) Razafim. & B.Bremer alleviates diabetic erectile dysfunction by attenuating oxidative stress and regulating PI3K/Akt/eNOS pathway
doi : 10.1016/j.jep.2023.116249
Volume 307, 10 May 2023, 116249
Effects of modified Huangqi Chifeng decoction on the IL-17 signaling pathway in an IgA nephropathy rat model
doi : 10.1016/j.jep.2023.116220
Volume 307, 10 May 2023, 116220
Antitumor mechanism of kangliu pill on gliomas in mice through PI3K-Akt signaling pathway
doi : 10.1016/j.jep.2023.116252
Volume 307, 10 May 2023, 116252
Toxicogenic effects of the mushroom Ganoderma lucidum on human liver and kidney tumor cells and peripheral blood lymphocytes
doi : 10.1016/j.jep.2023.116226
Volume 307, 10 May 2023, 116226
The activation of histone deacetylases 4 prevented endothelial dysfunction: A crucial mechanism of HuangqiGuizhiWuwu Decoction in improving microcirculation dysfunction in diabetes
doi : 10.1016/j.jep.2023.116240
Volume 307, 10 May 2023, 116240
Huanglian-Houpo extract attenuates DSS-induced UC mice by protecting intestinal mucosal barrier and regulating macrophage polarization
doi : 10.1016/j.jep.2023.116181
Volume 307, 10 May 2023, 116181
Biochemical and histological insights of 1,4-polyisoprene isolated from Sphenocentrum jollyanum pierre (menispermaceae) stem in wound healing activity in streptozotocin-induced diabetic rats
doi : 10.1016/j.jep.2023.116248
Volume 307, 10 May 2023, 116248
Editorial: Network pharmacology and AI
doi : 10.1016/j.jep.2023.116260
Volume 307, 10 May 2023, 116260
Amelioration of chronic prostatitis by fractions of Mongolian medicine Hosta plantaginea flowers via inhibition of NF-κB, MAPKs, JAK-STAT, and PI3K-Akt signaling pathways in rats
doi : 10.1016/j.jep.2023.116245
Volume 307, 10 May 2023, 116245
