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From AI to the Y chromosome (and everything in between)
doi : 10.1038/s41587-023-02076-0
Volume 41 Issue 12, December 2023
Bioengineered spider silk without critters
Kenna Hughes-CastleberryÂÂ
Nature Biotechnology’s academic spinouts 2022
Michael Eisenstein, Charles Schmidt & Laura DeFrancescoÂ
The global patent landscape of artificial intelligence applications for cancer
Luiza Braga, Renato Lopes, Luiz Alves & Fabio MotaÂ
Wireless multisite physiological sensor with clinical-grade accuracy
Rong LiÂÂ
Engineered upstream open reading frames predictably downregulate mRNA translation in plants
Measuring the impact of chromatin context on transcription factor binding affinities
Expanding access to CAR T cell therapies through local manufacturing
Magdi Elsallab & Marcela V. MausÂ
The chemistry of next-generation sequencing
Raphaël Rodriguez & Yamuna KrishnanÂ
Soil microbiome engineering for sustainability in a changing environment
Janet K. Jansson, Ryan McClure & Robert G. EgbertÂ
Trans-segmental imaging in the spinal cord of behaving mice
Pavel Shekhtmeyster, Daniela Duarte, Erin M. Carey, Alexander Ngo, Grace Gao, Jack A. Olmstead, Nicholas A. Nelson & Axel NimmerjahnÂ
Genetically encoded barcodes for correlative volume electron microscopy
Felix Sigmund, Oleksandr Berezin, Sofia Beliakova, Bernhard Magerl, Martin Drawitsch, Alberto Piovesan, Filipa Gonçalves, Silviu-Vasile Bodea, Stefanie Winkler, Zoe Bousraou, Martin Grosshauser, Eleni Samara, Jesús Pujol-MartÃÂ, Sebastian Schädler, Chun So, Stephan Irsen, Axel Walch, Florian Kofler, Marie Piraud, Joergen Kornfeld, Kevin Briggman & Gil Gregor WestmeyerÂ
SEACells infers transcriptional and epigenomic cellular states from single-cell genomics data
Sitara Persad, Zi-Ning Choo, Christine Dien, Noor Sohail, Ignas Masilionis, Ronan Chaligné, Tal Nawy, Chrysothemis C. Brown, Roshan Sharma, Itsik Pe’er, Manu Setty & Dana Pe’erÂ
Tuning plant phenotypes by precise, graded downregulation of gene expression
Chenxiao Xue, Fengti Qiu, Yuxiang Wang, Boshu Li, Kevin Tianmeng Zhao, Kunling Chen & Caixia GaoÂ
Multimodal spatiotemporal phenotyping of human retinal organoid development
Philipp Wahle, Giovanna Brancati, Christoph Harmel, Zhisong He, Gabriele Gut, Jacobo Sarabia del Castillo, Aline Xavier da Silveira dos Santos, Qianhui Yu, Pascal Noser, Jonas Simon Fleck, Bruno Gjeta, Dinko Pavlinić, Simone Picelli, Max Hess, Gregor W. Schmidt, Tom T. A. Lummen, Yanyan Hou, Patricia Galliker, David Goldblum, Marton Balogh, Cameron S. Cowan, Hendrik P. N. Scholl, Botond Roska, Magdalena Renner, …J. Gray CampÂ
Global detection of human variants and isoforms by deep proteome sequencing
Pavel Sinitcyn, Alicia L. Richards, Robert J. Weatheritt, Dain R. Brademan, Harald Marx, Evgenia Shishkova, Jesse G. Meyer, Alexander S. Hebert, Michael S. Westphall, Benjamin J. Blencowe, Jürgen Cox & Joshua J. CoonÂ
Epicardioid single-cell genomics uncovers principles of human epicardium biology in heart development and disease
Anna B. Meier, Dorota Zawada, Maria Teresa De Angelis, Laura D. Martens, Gianluca Santamaria, Sophie Zengerle, Monika Nowak-Imialek, Jessica Kornherr, Fangfang Zhang, Qinghai Tian, Cordula M. Wolf, Christian Kupatt, Makoto Sahara, Peter Lipp, Fabian J. Theis, Julien Gagneur, Alexander Goedel, Karl-Ludwig Laugwitz, Tatjana Dorn & Alessandra MorettiÂ
Quantification of absolute transcription factor binding affinities in the native chromatin context using BANC-seq
Hannah K. Neikes, Katarzyna W. Kliza, Cathrin Gräwe, Roelof A. Wester, Pascal W. T. C. Jansen, Lieke A. Lamers, Marijke P. Baltissen, Simon J. van Heeringen, Colin Logie, Sarah A. Teichmann, Rik G. H. Lindeboom & Michiel VermeulenÂ
Protein structure prediction with in-cell photo-crosslinking mass spectrometry and deep learning
Kolja Stahl, Andrea Graziadei, Therese Dau, Oliver Brock & Juri RappsilberÂ
Contamination source modeling with SCRuB improves cancer phenotype prediction from microbiome data
George I. Austin, Heekuk Park, Yoli Meydan, Dwayne Seeram, Tanya Sezin, Yue Clare Lou, Brian A. Firek, Michael J. Morowitz, Jillian F. Banfield, Angela M. Christiano, Itsik Pe’er, Anne-Catrin Uhlemann, Liat Shenhav & Tal KoremÂ
Collectively building a mentor–mentee relationship through a one-day workshop
Julie Foncy, Marta Kwapisz, Martine Knibiehler & Julie BatutÂ
