Posttherapy histologic features of the prostate gland

Treatment type	Changes in prostate cancer cells	Changes in benign epithelium
Androgen ablation	Severe atrophic changes Clear or vacuolated cytoplasm Decreased nuclear atypia (Retained infiltrating pattern)	Severe atrophy Basal cell hyperplasia
Estrogen	Atrophic changes Squamous metaplasia	Squamous metaplasia
Finasteride and dutasteride	Minimal changes	Mild atrophy
Radiation therapy	Degenerative changes (Retained infiltrating pattern)	Marked nuclear atypia

Post_therapy_histology_pros.htm

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