ﺑﺎﺯﮔﺸﺖ ﺑﻪ ﺻﻔﺤﻪ ﻗﺒﻠﯽ
خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
نسخه الکترونیک
medimedia.ir

Medications that may affect bronchoprovocation challenge test[1-3]

Medications that may affect bronchoprovocation challenge test[1-3]
Medication Minimum time to omit medication before challenge tests
Inhaled bronchodilators
Albuterol 8 hours
Levalbuterol 8 hours
Terbutaline 8 hours
Formoterol, salmeterol 36 hours
Ultra long-acting beta agonists (eg, indacaterol, olodaterol, vilanterol) 48 hours
Short-acting muscarinic antagonist (ipratropium) 12 hours 
Long-acting muscarinic antagonists (aclidinium, glycopyrrolate, tiotropium) 72 hours
Oral theophylline 24 hours
Oral albuterol 12 to 24 hours
Inhaled glucocorticoid (budesonide, fluticasone propionate)* 6 hours
Inhaled glucocorticoid (long acting; fluticasone furoate, ciclesonide) 24 hours 
Oral glucocorticoid* 2 to 3 weeks
Cromolyn sodium 4 hours
Antihistamines (cetirizine, fexofenadine, loratadine) 72 hoursΔ
Leukotriene modifiers
Montelukast◊ 4 days
Zafirlukast 4 days
* The authors do not recommend routinely withholding inhaled or oral glucocorticoids, but their anti-inflammatory effect may decrease bronchial responsiveness. A negative test while the patient is using glucocorticoids implies that the patient's current symptoms are not due to asthma.
¶ Cromolyn has minimal effect on methacholine bronchoprovocation challenge, but should be withheld prior to allergen challenge.
Δ Antihistamines are discontinued because of their anticholinergic effect.
◊ A single dose of montelukast has minimal effect on methacholine challenge, but a withhold time of 4 to 8 weeks would be needed for full resolution of the anti-inflammatory effects.
References:
  1. Weiler JM, Brannan JD, Randolph CC, et al. Exercise-induced bronchoconstriction update-2016. J Allergy Clin Immunol 2016; 138: 1292–1295.
  2. Coates AL, Wanger J, Cockcroft DW, et al. ERS technical standard on bronchial challenge testing: general considerations and performance of methacholine challenge tests. Eur Respir J 2017; 49.
  3. Hallstrand TS, Leuppi JD, et al. ERS technical standard on bronchial challenge testing: pathophysiology and methodology of indirect airway challenge testing. Eur Respir J 2018; 52:1801033.
Graphic 62151 Version 10.0

آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟