Change in bone mineral density in adults with asthma taking inhaled glucocorticoids

For both the total hip and the trochanter, the rate of decline in bone density was 0.00044 g/cm² per year for each additional daily puff of inhaled glucocorticoid (p = 0.01 and p = 0.005, respectively). The solid line in each panel represents the mean yearly change in bone density. The dashed lines indicate the 95 percent confidence interval for the mean.