Manhattan plot for displaying information from a genome-wide association study

Example of a Manhattan plot. This type of plot is used to represent and summarize results from a genome-wide association study (GWAS). The x-axis plots the physical positions of single nucleotide polymorphisms (SNPs) along each chromosome, and the y-axis plots the inverse logarithm of the P-value for the association of each SNP with the trait of interest. A higher value on the y-axis reflects a more significant association. The dashed red line shows the significance threshold for genome-wide significance; data points (SNPs) above this line are considered significant. This type of plot was named for its similarity to the appearance of skyscrapers in the skyline of Manhattan in the United States.