Annals of the Rheumatic Diseases




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سفارش

Antiphospholipid antibodies and COVID-19 thrombotic vasculopathy: one swallow does not make a summer

Pier Luigi Meroni, Maria Orietta Borghi

doi : 10.1136/annrheumdis-2021-220520

Annals of the Rheumatic Diseases 2021;80:1105-1107

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Henrik Sjögren (1899–1986): the syndrome and his legacy

Roland Jonsson

doi : 10.1136/annrheumdis-2021-219942

Annals of the Rheumatic Diseases 2021;80:1108-1109

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EULAR COVID-19 registry: lessons learnt and future considerations

Saskia Lawson-Tovey, Anja Strangfeld, Kimme L Hyrich, Loreto Carmona, Diana Rodrigues, Laure Gossec, Elsa F Mateus, Pedro M Machado

doi : 10.1136/annrheumdis-2021-220319

Annals of the Rheumatic Diseases 2021;80:1110-1115

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EULAR Points to Consider (PtC) for designing, analysing and reporting of studies with work participation as an outcome domain in patients with inflammatory arthritis

Annelies Boonen, Polina Putrik, Mary Lucy Marques, Alessia Alunno, Lydia Abasolo, Dorcas Beaton, Neil Betteridge, Mathilda Bjørk, Maarten Boers, Boryana Boteva, Bruno Fautrel, Francis Guillemin, Elsa F Mateus, Elena Nikiphorou, Márta Péntek, Fernando Pimentel Santos, Johannes L Severens, Suzanne M M Verstappen, Karen Walker-Bone, Johan Karlsson Wallman, Marieke M ter Wee, René Westhovens, Sofia Ramiro

doi : 10.1136/annrheumdis-2020-219523

Annals of the Rheumatic Diseases 2021;80:1116-1123

Clinical studies with work participation (WP) as an outcome domain pose particular methodological challenges that hamper interpretation, comparison between studies and meta-analyses.

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Glucocorticoid discontinuation in patients with early rheumatoid and undifferentiated arthritis: a post-hoc analysis of the BeSt and IMPROVED studies

Johanna Maria Maassen, Raquel Dos Santos Sobrín, Sytske Anne Bergstra, Robbert Goekoop, Tom W J Huizinga, Cornelia F Allaart

doi : 10.1136/annrheumdis-2021-220403

Annals of the Rheumatic Diseases 2021;80:1124-1129

To evaluate the success rate of glucocorticoid discontinuation and to study which factors are associated with successful discontinuation.

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Efficacy and safety of tofacitinib versus baricitinib in patients with rheumatoid arthritis in real clinical practice: analyses with propensity score-based inverse probability of treatment weighting

Yusuke Miyazaki, Kazuhisa Nakano, Shingo Nakayamada, Satoshi Kubo, Yoshino Inoue, Yoshihisa Fujino, Yoshiya Tanaka

doi : 10.1136/annrheumdis-2020-219699

Annals of the Rheumatic Diseases 2021;80:1130-1136

The differences of efficacy between each Janus kinase (JAK) inhibitors have not been clarified in the patients with rheumatoid arthritis (RA) in clinical practice. Here, we compared the efficacy between tofacitinib (TOFA) and baricitinib (BARI) in clinical practice.

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Associations of baseline use of biologic or targeted synthetic DMARDs with COVID-19 severity in rheumatoid arthritis: Results from the COVID-19 Global Rheumatology Alliance physician registry

Jeffrey A Sparks, Zachary S Wallace, Andrea M Seet, Milena A Gianfrancesco, Zara Izadi, Kimme L Hyrich, Anja Strangfeld, Laure Gossec, Loreto Carmona, Elsa F Mateus, Saskia Lawson-Tovey, Laura Trupin, Stephanie Rush, Patricia Katz, Gabriela Schmajuk, Lindsay Jacobsohn, Leanna Wise, Emily L Gilbert, Ali Duarte-García, Maria O Valenzuela-Almada, Guillermo J Pons-Estel, Carolina A Isnardi, Guillermo A Berbotto, Tiffany Y -T Hsu, Kristin M D’Silva, Naomi J Patel, Lianne Kearsley-Fleet, Martin Schäfer, Sandra Lúcia Euzébio Ribeiro, Samar Al Emadi, Liselotte Tidblad, Carlo Alberto Scirè, Bernd Raffeiner, Thierry Thomas, René-Marc Flipo, Jérôme Avouac, Raphaèle Seror, Miguel Bernardes, Maria Margarida Cunha, Rebecca Hasseli, Hendrik Schulze-Koops, Ulf Müller-Ladner, Christof Specker, Viviane Angelina de Souza, Licia Maria Henrique da Mota, Ana Paula Monteiro Gomides, Philippe Dieudé, Elena Nikiphorou, Vanessa L Kronzer, Namrata Singh, Manuel F Ugarte-Gil, Beth Wallace, Akpabio Akpabio, Ranjeny Thomas, Suleman Bhana, Wendy Costello, Rebecca Grainger, Jonathan S Hausmann, Jean W Liew, Emily Sirotich, Paul Sufka, Philip C Robinson, Pedro M Machado, Jinoos Yazdany

doi : 10.1136/annrheumdis-2021-220418

Annals of the Rheumatic Diseases 2021;80:1137-1146

To investigate baseline use of biologic or targeted synthetic (b/ts) disease-modifying antirheumatic drugs (DMARDs) and COVID-19 outcomes in rheumatoid arthritis (RA).

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Efficacy and safety of tildrakizumab in patients with active psoriatic arthritis: results of a randomised, double-blind, placebo-controlled, multiple-dose, 52-week phase IIb study

Philip J Mease, Saima Chohan, Ferran J Garcia Fructuoso, Michael E Luggen, Proton Rahman, Siba P Raychaudhuri, Richard C Chou, Alan M Mendelsohn, Stephen J Rozzo, Alice Gottlieb

doi : 10.1136/annrheumdis-2020-219014

Annals of the Rheumatic Diseases 2021;80:1147-1157

To evaluate efficacy and safety of the anti-interleukin-23p19 monoclonal antibody tildrakizumab in patients with psoriatic arthritis (PsA).

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Safety and efficacy of faecal microbiota transplantation for active peripheral psoriatic arthritis: an exploratory randomised placebo-controlled trial

Maja Skov Kragsnaes, Jens Kjeldsen, Hans Christian Horn, Heidi Lausten Munk, Jens Kristian Pedersen, Søren Andreas Just, Palle Ahlquist, Finn Moeller Pedersen, Maarten de Wit, Sören Möller, Vibeke Andersen, Karsten Kristiansen, Dorte Kinggaard Holm, Hanne Marie Holt, Robin Christensen, Torkell Ellingsen

doi : 10.1136/annrheumdis-2020-219511

Annals of the Rheumatic Diseases 2021;80:1158-1167

Although causality remains to be established, targeting dysbiosis of the intestinal microbiota by faecal microbiota transplantation (FMT) has been proposed as a novel treatment for inflammatory diseases. In this exploratory, proof-of-concept study, we evaluated the safety and efficacy of FMT in psoriatic arthritis (PsA).

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Polygenic Risk Scores have high diagnostic capacity in ankylosing spondylitis

Zhixiu Li, Xin Wu, Paul J Leo, Erika De Guzman, Nurullah Akkoc, Maxime Breban, Gary J Macfarlane, Mahdi Mahmoudi, Helena Marzo-Ortega, Lisa K Anderson, Lawrie Wheeler, Chung-Tei Chou, Andrew A Harrison, Simon Stebbings, Gareth T Jones, So-Young Bang, Geng Wang, Ahmadreza Jamshidi, Elham Farhadi, Jing Song, Li Lin, Mengmeng Li, James Cheng-Chung Wei, Nicholas G Martin, Margaret J Wright, MinJae Lee, Yuqin Wang, Jian Zhan, Jin-San Zhang, Xiaobing Wang, Zi-Bing Jin, Michael H Weisman, Lianne S Gensler, Michael M Ward, Mohammad Hossein Rahbar, Laura Diekman, Tae-Hwan Kim, John D Reveille, Bryan Paul Wordsworth, Huji Xu, Matthew A Brown

doi : 10.1136/annrheumdis-2020-219446

Annals of the Rheumatic Diseases 2021;80:1168-1174

We sought to test the hypothesis that Polygenic Risk Scores (PRSs) have strong capacity to discriminate cases of ankylosing spondylitis (AS) from healthy controls and individuals in the community with chronic back pain.

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Quality indicators for systemic lupus erythematosus based on the 2019 EULAR recommendations: development and initial validation in a cohort of 220 patients

Katerina Chavatza, Myrto Kostopoulou, Dionysis Nikolopoulos, Ourania Gioti, Konstantina Togia, Laura Andreoli, Martin Aringer, John Boletis, Andrea Doria, Frederic A Houssiau, David Jayne, Marta Mosca, Elisabet Svenungsson, Angela Tincani, George Bertsias, Antonis Fanouriakis, Dimitrios T Boumpas

doi : 10.1136/annrheumdis-2021-220438

Annals of the Rheumatic Diseases 2021;80:1175-1182

Quality of care is receiving increased attention in systemic lupus erythematosus (SLE). We developed quality indicators (QIs) for SLE based on the 2019 update of European League Against Rheumatism recommendations.

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Interaction between the STAT4 rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus

Sarah Reid, Niklas Hagberg, Johanna K Sandling, Andrei Alexsson, Pascal Pucholt, Christopher Sjöwall, Karoline Lerang, Andreas Jönsen, Iva Gunnarsson, Ann-Christine Syvänen, Anne Margrethe Troldborg, Anne Voss, Anders A Bengtsson, Øyvind Molberg, Søren Jacobsen, Elisabet Svenungsson, Lars Rönnblom, Dag Leonard

doi : 10.1136/annrheumdis-2020-219727

Annals of the Rheumatic Diseases 2021;80:1183-1189

To investigate how genetics influence the risk of smoking-related systemic lupus erythematosus (SLE) manifestations.

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B cell subset composition segments clinically and serologically distinct groups in chronic cutaneous lupus erythematosus

Scott A Jenks, Chungwen Wei, Regina Bugrovsky, Aisha Hill, Xiaoqian Wang, Francesca M Rossi, Kevin Cashman, Matthew C Woodruff, Laura D Aspey, S. Sam Lim, Gaobin Bao, Cristina Drenkard, Ignacio Sanz

doi : 10.1136/annrheumdis-2021-220349

Annals of the Rheumatic Diseases 2021;80:1190-1200

While the contribution of B-cells to SLE is well established, its role in chronic cutaneous lupus erythematosus (CCLE) remains unclear. Here, we compare B-cell and serum auto-antibody profiles between patients with systemic lupus erythematosus (SLE), CCLE, and overlap conditions.

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Immune response to dermatomyositis-specific autoantigen, transcriptional intermediary factor 1? can result in experimental myositis

Naoko Okiyama, Yuki Ichimura, Miwako Shobo, Ryota Tanaka, Noriko Kubota, Akimasa Saito, Yosuke Ishitsuka, Rei Watanabe, Yasuhiro Fujisawa, Yoshiyuki Nakamura, Akihiro Murakami, Hisako Kayama, Kiyoshi Takeda, Manabu Fujimoto

doi : 10.1136/annrheumdis-2020-218661

Annals of the Rheumatic Diseases 2021;80:1201-1208

To investigate whether autoimmunity to transcriptional intermediary factor 1 (TIF1)?, a ubiquitous nuclear autoantigen for myositis-specific autoantibodies detected in patients with dermatomyositis (DM) is pathogenetic for inflammatory myopathy.

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circPDE4B prevents articular cartilage degeneration and promotes repair by acting as a scaffold for RIC8A and MID1

Shuying Shen, Yute Yang, Panyang Shen, Jun Ma, Bin Fang, Qingxin Wang, Kefan Wang, Peihua Shi, Shunwu Fan, Xiangqian Fang

doi : 10.1136/annrheumdis-2021-219969

Annals of the Rheumatic Diseases 2021;80:1209-1219

Circular RNAs (circRNAs) have emerged as significant biological regulators. Herein, we aimed to elucidate the role of an unidentified circRNA (circPDE4B) that is reportedly downregulated in osteoarthritis (OA) tissues.

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Variants in urate transporters, ADH1B, GCKR and MEPE genes associate with transition from asymptomatic hyperuricaemia to gout: results of the first gout versus asymptomatic hyperuricaemia GWAS in Caucasians using data from the UK Biobank

Gabriela Sandoval-Plata, Kevin Morgan, Abhishek Abhishek

doi : 10.1136/annrheumdis-2020-219796

Annals of the Rheumatic Diseases 2021;80:1220-1226

To perform a genome-wide association study (GWAS) of gout cases versus asymptomatic hyperuricaemia (AH) controls, and gout cases versus normouricaemia controls, and to generate a polygenic risk score (PRS) to determine gout-case versus AH-control status.

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Genome-wide association study identifies RNF123 locus as associated with chronic widespread musculoskeletal pain

Md Shafiqur Rahman, Bendik S Winsvold, Sergio O Chavez Chavez, Sigrid Børte, Yakov A Tsepilov, Sodbo Zh Sharapov, HUNT All-In Pain, Yurii S Aulchenko, Knut Hagen, Egil A Fors, Kristian Hveem, John Anker Zwart, Joyce B van Meurs, Maxim B Freidin, Frances MK Williams

doi : 10.1136/annrheumdis-2020-219624

Annals of the Rheumatic Diseases 2021;80:1227-1235

Chronic widespread musculoskeletal pain (CWP) is a symptom of fibromyalgia and a complex trait with poorly understood pathogenesis. CWP is heritable (48%–54%), but its genetic architecture is unknown and candidate gene studies have produced inconsistent results. We conducted a genome-wide association study to get insight into the genetic background of CWP.

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Anticardiolipin and other antiphospholipid antibodies in critically ill COVID-19 positive and negative patients

Uriel Trahtemberg, Robert Rottapel, Claudia C Dos Santos, Arthur S Slutsky, Andrew Baker, Marvin J Fritzler

doi : 10.1136/annrheumdis-2021-220206

Annals of the Rheumatic Diseases 2021;80:1236-1240

Reports of severe COVID-19 being associated with thrombosis, antiphospholipid antibodies (APLA), and antiphospholipid syndrome have yielded disparate conclusions. Studies comparing patients with COVID-19 with contemporaneous controls of similar severity are lacking.

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Challenges in the diagnosis of early rheumatoid arthritis in times of COVID-19

Bernardo D'Onofrio, Ludovico De Stefano, Bianca Lucia Palermo, Blerina Xoxi, Antonio Manzo, Carlomaurizio Montecucco, Serena Bugatti

doi : 10.1136/annrheumdis-2021-220219

Annals of the Rheumatic Diseases 2021;80:1242-1243

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Ensuring tight control in patients with rheumatoid arthritis treated with targeted therapies during the COVID-19 pandemic using a telehealth strategy

Francesca Ingegnoli, Gilberto Cincinelli, Angela Flavia Luppino, Ennio Giulio Favalli, Annalisa Orenti, Patrizia Boracchi, Roberto Caporali

doi : 10.1136/annrheumdis-2021-220142

Annals of the Rheumatic Diseases 2021;80:1243-1245

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Use of Janus kinase inhibitors in COVID-19: a prospective observational series in 522 individuals

Oleg Melikhov, Tatiana Kruglova, Karine Lytkina, Georgy Melkonyan, Elena Prokhorovich, Gleb Putsman, Grigory Rodoman, Arkady Vertkin, Alena Zagrebneva, Justin Stebbing

doi : 10.1136/annrheumdis-2021-220049

Annals of the Rheumatic Diseases 2021;80:1245-1246

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Microarray evaluation of allergen-specific IgE in eosinophilic granulomatosis with polyangiitis

Federica Bello, Federica Maritati, Antonella Radice, Renato Alberto Sinico, Giacomo Emmi, Augusto Vaglio

doi : 10.1136/annrheumdis-2021-220111

Annals of the Rheumatic Diseases 2021;80:1247-1248

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Medications associated with fracture risk in patients with rheumatoid arthritis

Yi-Sheng Liou, Tsung-Kun Lin, Hung-Yi Chen, Gwo-Ping Jong

doi : 10.1136/annrheumdis-2019-216262

Annals of the Rheumatic Diseases 2021;80:e140

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Response to: ‘Medications associated with fracture risk in patients with rheumatoid arthritis’ by Chen et al 

Gulsen Ozen, Kaleb Michaud

doi : 10.1136/annrheumdis-2019-216293

Annals of the Rheumatic Diseases 2021;80:e141

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Diabetes mellitus in ankylosing spondylitis

Young Ho Lee, Gwan Gyu Song

doi : 10.1136/annrheumdis-2019-216335

Annals of the Rheumatic Diseases 2021;80:e142

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Response to: ‘Diabetes mellitus in ankylosing spondylitis’ by Lee and Song

Shih-Wei Lai, Yu-Hung Kuo, Kuan-Fu Liao

doi : 10.1136/annrheumdis-2019-216429

Annals of the Rheumatic Diseases 2021;80:e143

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Incidence of inflammatory bowel disease in patients with ankylosing spondylitis

Shih-Wei Lai, Yu-Hung Kuo, Kuan-Fu Liao

doi : 10.1136/annrheumdis-2019-216362

Annals of the Rheumatic Diseases 2021;80:e144

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Application of MS score in macrophage activation syndrome patients associated with adult onset Still’s disease

Ran Wang, Ting Li, Shuang Ye, Wenefng Tan, Cheng Zhao, Yisha Li, Chunde Bao, Qiong Fu

doi : 10.1136/annrheumdis-2019-216286

Annals of the Rheumatic Diseases 2021;80:e145

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Response to ‘Application of MS score in macrophage activation syndrome patients associated with adult onset Still’s disease’ by Wang et al 

Francesca Minoia, Angelo Ravelli

doi : 10.1136/annrheumdis-2019-216310

Annals of the Rheumatic Diseases 2021;80:e146

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Overlap of systemic lupus erythematosus and myositis is rare in anti-Ku antibody-positive patients

Mariko Ogawa-Momohara, Yoshinao Muro, Masashi Akiyama

doi : 10.1136/annrheumdis-2019-216375

Annals of the Rheumatic Diseases 2021;80:e147

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Response to: ‘Overlap of systemic lupus erythematosus and myositis is rare in anti-Ku antibody-positive patients’ by Ogawa-Momohara et al 

Lionel Spielmann, Benoit Nespola, Alain Meyer

doi : 10.1136/annrheumdis-2019-216413

Annals of the Rheumatic Diseases 2021;80:e148

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In search for the ideal anatomical composition of vascularised human skin equivalents for systemic sclerosis translational research: should we recruit the telocytes?

Mirko Manetti, Marco Matucci-Cerinic

doi : 10.1136/annrheumdis-2019-216371

Annals of the Rheumatic Diseases 2021;80:e149

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Response to: ‘In search for the ideal anatomical composition of vascularised human skin equivalents for systemic sclerosis translational research: should we recruit the telocytes?’ by Manetti and Matucci-Cerinic

Alexandru Emil Matei, Jörg H W Distler

doi : 10.1136/annrheumdis-2019-216393

Annals of the Rheumatic Diseases 2021;80:e150

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Association of anti-Ro52 autoantibodies with interstitial lung disease in connective tissue diseases

Si Wu, Xiaojun Tang, Liping Wu, Liang-jing Lu, Xuebing Feng

doi : 10.1136/annrheumdis-2019-216372

Annals of the Rheumatic Diseases 2021;80:e151

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NLRP12 gene mutation in India: case finding and diagnosis made easy in the days of whole exome sequencing

Kanjaksha Ghosh

doi : 10.1136/annrheumdis-2019-216270

Annals of the Rheumatic Diseases 2021;80:e152

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Correction: First external validation of sensitivity and specificity of the European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) classification criteria for idiopathic inflammatory myopathies with a Japanese cohort

doi : 10.1136/annrheumdis-2019-215488corr1

Annals of the Rheumatic Diseases 2021;80:e153

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Correction: New composite endpoint in early diffuse cutaneous systemic sclerosis: revisiting the provisional American College of Rheumatology Composite Response Index in Systemic Sclerosis

doi : 10.1136/annrheumdis-2020-219100corr1

Annals of the Rheumatic Diseases 2021;80:e154

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Correction: EULAR recommendations for the reporting of ultrasound studies in rheumatic and musculoskeletal diseases (RMDs)

doi : 10.1136/annrheumdis-2020-219816corr1

Annals of the Rheumatic Diseases 2021;80:e155

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