دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه
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Extending the Product Label for Ticagrelor: Looking Under the FDA Hood
Paul W. Armstrong
doi : 10.1161/CIRCULATIONAHA.121.055907
Circulation. 2021;144:583–585
Cardiovascular Health, Disease, and Care in Russia
Simon Matskeplishvili, Anna Kontsevaya
doi : 10.1161/CIRCULATIONAHA.121.055239
Circulation. 2021;144:586–588
Toward Replacing Late Gadolinium Enhancement With Artificial Intelligence Virtual Native Enhancement for Gadolinium-Free Cardiovascular Magnetic Resonance Tissue Characterization in Hypertrophic Cardiomyopathy
Qiang Zhang, Matthew K. Burrage, Elena Lukaschuk, Mayooran Shanmuganathan, Iulia A. Popescu, Chrysovalantou Nikolaidou, Rebecca Mills, Konrad Werys, Evan Hann, Ahmet Barutcu, Suleyman D. Polat, and Hypertrophic Cardiomyopathy Registry (HCMR) Investigators, Michael Salerno, Michael Jerosch-Herold, Raymond Y. Kwong, Hugh C. Watkins, Christopher M. Kramer, Stefan Neubauer, Vanessa M. Ferreira, Stefan K. Piechnik See fewer authors
doi : 10.1161/CIRCULATIONAHA.121.054432
Circulation. 2021;144:589–599
Late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) imaging is the gold standard for noninvasive myocardial tissue characterization but requires intravenous contrast agent administration. It is highly desired to develop a contrast agent–free technology to replace LGE for faster and cheaper CMR scans.
Automated Noncontrast Myocardial Tissue Characterization for Hypertrophic Cardiomyopathy: Holy Grail or False Prophet?
Charlotte H Manisty, Jennifer H. Jordan, W. Gregory Hundley
doi : 10.1161/CIRCULATIONAHA.121.055791
Circulation. 2021;144:600–603
Derivation and Validation of a 10-Year Risk Score for Symptomatic Abdominal Aortic Aneurysm: Cohort Study of Nearly 500 000 Individuals
Paul Welsh, Claire E. Welsh, Pardeep S. Jhund, Mark Woodward, Rosemary Brown, Jim Lewsey, Carlos A. Celis-Morales, Frederick K. Ho, Daniel F. MacKay, Jason M.R. Gill, Stuart R. Gray, S. Vittal Katikireddi, Jill P. Pell, John Forbes, Naveed Sattar
doi : 10.1161/CIRCULATIONAHA.120.053022
Circulation. 2021;144:604–614
Abdominal aortic aneurysm (AAA) can occur in patients who are ineligible for routine ultrasound screening. A simple AAA risk score was derived and compared with current guidelines used for ultrasound screening of AAA.
Metabolic Syndrome Mediates ROS-miR-193b-NFYA–Dependent Downregulation of Soluble Guanylate Cyclase and Contributes to Exercise-Induced Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction
Taijyu Satoh, Longfei Wang, Cristina Espinosa-Diez, Bing Wang, Scott A. Hahn, Kentaro Noda, Elizabeth R. Rochon, Matthew R. Dent, Andrea R. Levine, Jeffrey J. Baust, Samuel Wyman, Yijen L. Wu, Georgios A. Triantafyllou, Ying Tang, Mike Reynolds, Sruti Shiva, Cynthia St. Hilaire, Delphine Gomez, Dmitry A. Goncharov, Elena A. Goncharova, Stephen Y. Chan, Adam C. Straub, Yen-Chun Lai, Charles F. McTiernan, Mark T. Gladwin
doi : 10.1161/CIRCULATIONAHA.121.053889
Circulation. 2021;144:615–637
Many patients with heart failure with preserved ejection fraction have metabolic syndrome and develop exercise-induced pulmonary hypertension (EIPH). Increases in pulmonary vascular resistance in patients with heart failure with preserved ejection fraction portend a poor prognosis; this phenotype is referred to as combined precapillary and postcapillary pulmonary hypertension (CpcPH). Therapeutic trials for EIPH and CpcPH have been disappointing, suggesting the need for strategies that target upstream mechanisms of disease. This work reports novel rat EIPH models and mechanisms of pulmonary vascular dysfunction centered around the transcriptional repression of the soluble guanylate cyclase (sGC) enzyme in pulmonary artery (PA) smooth muscle cells.
HINT1 (Histidine Triad Nucleotide-Binding Protein 1) Attenuates Cardiac Hypertrophy Via Suppressing HOXA5 (Homeobox A5) Expression
Yan Zhang, Qiang Da, Siyi Cao, Ke Yan, Zhiguang Shi, Qing Miao, Chen Li, Lulu Hu, Shixiu Sun, Wei Wu, Lingxiang Wu, Feng Chen, Liansheng Wang, Yuanqing Gao, Zhengrong Huang, Yongfeng Shao, Hongshan Chen, Yongyue Wei, Feng Chen, Yi Han, Liping Xie, Yong Ji
doi : 10.1161/CIRCULATIONAHA.120.051094
Circulation. 2021;144:638–654
Cardiac hypertrophy is an important prepathology of, and will ultimately lead to, heart failure. However, the mechanisms underlying pathological cardiac hypertrophy remain largely unknown. This study aims to elucidate the effects and mechanisms of HINT1 (histidine triad nucleotide–binding protein 1) in cardiac hypertrophy and heart failure.
Applying Decision Analysis to Inform the US Food and Drug Administration’s Benefit–Risk Assessment of Ticagrelor for Primary Prevention of Myocardial Infarction or Stroke Based on THEMIS
Leila G. Lackey, Christine E. Garnett, Fred Senatore
doi : 10.1161/CIRCULATIONAHA.120.053294
Circulation. 2021;144:655–658
Wide QRS Complex Bradycardia in a Hemodynamically Unstable Young Woman
Sascha Macherey, Jan-Malte Sinning, Victor Mauri
doi : 10.1161/CIRCULATIONAHA.121.055655
Circulation. 2021;144:659–661
Identification of a Functional PDE5A Variant at the Chromosome 4q27 Coronary Artery Disease Locus in an Extended Myocardial Infarction Family
Tan An Dang, Thorsten Kessler, Jana Wobst, Michael Wierer, Ingrid Braenne, Tim M. Strom, Stephanie Tennstedt, Hendrik B. Sager, Thomas Meitinger, Jeanette Erdmann, Heribert Schunkert
doi : 10.1161/CIRCULATIONAHA.120.052975
Circulation. 2021;144:662–665
Letter by Reiffel Regarding Article, “Emulating Randomized Clinical Trials With Nonrandomized Real-World Evidence Studies: First Results From the RCT DUPLICATE Initiative”
James A. Reiffel
doi : 10.1161/CIRCULATIONAHA.121.054903
Circulation. 2021;144:e160
Letter by Olson et al Regarding Article, “Emulating Randomized Clinical Trials With Nonrandomized Real-World Evidence Studies: First Results From the RCT DUPLICATE Initiative”
Melvin (Skip) Olson, Chinmay Deshpande, Kristijan H. Kahler
doi : 10.1161/CIRCULATIONAHA.121.053935
Circulation. 2021;144:e161
Response by Franklin and Schneeweiss to Letters Regarding Article, “Emulating Randomized Clinical Trials With Nonrandomized Real-World Evidence Studies: First Results From the RCT DUPLICATE Initiative”
Jessica M. Franklin, Sebastian Schneeweiss
doi : 10.1161/CIRCULATIONAHA.121.055681
Circulation. 2021;144:e162–e163
Correction to: Effect of Neprilysin Inhibition on Left Ventricular Remodeling in Patients With Asymptomatic Left Ventricular Systolic Dysfunction Late After Myocardial Infarction
doi : 10.1161/CIR.0000000000001015
Circulation. 2021;144:e164
Correction to: Derivation and Validation of a 10-Year Risk Score for Symptomatic Abdominal Aortic Aneurysm: Cohort Study of Nearly 500 000 Individuals
doi : 10.1161/CIR.0000000000001010
Circulation. 2021;144:e165
