دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه
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Digital Redlining and Cardiovascular Innovation
Beza Merid, Maria Cielito Robles, Brahmajee K. Nallamothu
doi : 10.1161/CIRCULATIONAHA.121.056532
Circulation. 2021;144:913–915
Prevalence of Subclinical Coronary Artery Atherosclerosis in the General Population
Göran Bergström, Margaretha Persson, Martin Adiels, Elias Björnson, Carl Bonander, Håkan Ahlström, Joakim Alfredsson, Oskar Angerås, Göran Berglund, Anders Blomberg, John Brandberg, Mats Börjesson, Kerstin Cederlund, Ulf de Faire, Olov Duvernoy, Örjan Ekblom, Gunnar Engström, Jan E. Engvall, Erika Fagman, Mats Eriksson, David Erlinge, Björn Fagerberg, Agneta Flinck, Isabel Gonçalves, Emil Hagström, Ola Hjelmgren, Lars Lind, Eva Lindberg, Per Lindqvist, Johan Ljungberg, Martin Magnusson, Maria Mannila, Hanna Markstad, Moman A. Mohammad, Fredrik H. Nystrom, Ellen Ostenfeld, Anders Persson, Annika Rosengren, Anette Sandström, Anders Själander, Magnus C. Sköld, Johan Sundström, Eva Swahn, Stefan Söderberg, Kjell Torén, Carl Johan Östgren, Tomas Jernberg
doi : 10.1161/CIRCULATIONAHA.121.055340
Circulation. 2021;144:916–929
Early detection of coronary atherosclerosis using coronary computed tomography angiography (CCTA), in addition to coronary artery calcification (CAC) scoring, may help inform prevention strategies. We used CCTA to determine the prevalence, severity, and characteristics of coronary atherosclerosis and its association with CAC scores in a general population.
Population Screening With Coronary Computed Tomography Angiography and the Prevention of Coronary Events
Kuan Ken Lee, Ryan Wereski, Michelle C. Williams, Nicholas L. Mills
doi : 10.1161/CIRCULATIONAHA.121.055784
Circulation. 2021;144:930–933
One-Year Committed Exercise Training Reverses Abnormal Left Ventricular Myocardial Stiffness in Patients With Stage B Heart Failure With Preserved Ejection Fraction
Michinari Hieda, Satyam Sarma, Christopher M. Hearon Jr, James P. MacNamara, Katrin A. Dias, Mitchel Samels, Dean Palmer, Sheryl Livingston, Margot Morris, Benjamin D. Levine
doi : 10.1161/CIRCULATIONAHA.121.054117
Circulation. 2021;144:934–946
Individuals with left ventricular (LV) hypertrophy and elevated cardiac biomarkers in middle age are at increased risk for the development of heart failure with preserved ejection fraction. Prolonged exercise training reverses the LV stiffening associated with healthy but sedentary aging; however, whether it can also normalize LV myocardial stiffness in patients at high risk for heart failure with preserved ejection fraction is unknown. In a prospective, randomized controlled trial, we hypothesized that 1-year prolonged exercise training would reduce LV myocardial stiffness in patients with LV hypertrophy.
Therapeutic Inhibition of Acid-Sensing Ion Channel 1a Recovers Heart Function After Ischemia–Reperfusion Injury
Meredith A. Redd, Sarah E. Scheuer, Natalie J. Saez, Yusuke Yoshikawa, Han Sheng Chiu, Ling Gao, Mark Hicks, Jeanette E. Villanueva, Yashutosh Joshi, Chun Yuen Chow, Gabriel Cuellar-Partida, Jason N. Peart, Louise E. See Hoe, Xiaoli Chen, Yuliangzi Sun, Jacky Y. Suen, Robert J. Hatch, Ben Rollo, Di Xia, Mubarak A.H. Alzubaidi, Snezana Maljevic, Gregory A. Quaife-Ryan, James E. Hudson, Enzo R. Porrello, Melanie Y. White, Stuart J. Cordwell, John F. Fraser, Steven Petrou, Melissa E. Reichelt, Walter G. Thomas, Glenn F. King, Peter S. Macdonald, Nathan J. Palpant
doi : 10.1161/CIRCULATIONAHA.121.054360
Circulation. 2021;144:947–960
Ischemia–reperfusion injury (IRI) is one of the major risk factors implicated in morbidity and mortality associated with cardiovascular disease. During cardiac ischemia, the buildup of acidic metabolites results in decreased intracellular and extracellular pH, which can reach as low as 6.0 to 6.5. The resulting tissue acidosis exacerbates ischemic injury and significantly affects cardiac function.
Hyperglycemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis
Laurienne Edgar, Naveed Akbar, Adam T. Braithwaite, Thomas Krausgruber, Héctor Gallart-Ayala, Jade Bailey, Alastair L. Corbin, Tariq E. Khoyratty, Joshua T. Chai, Mohammad Alkhalil, André F. Rendeiro, Klemen Ziberna, Ritu Arya, Thomas J. Cahill, Christoph Bock, Jurga Laurencikiene, Mark J. Crabtree, Madeleine E. Lemieux, Niels P. Riksen, Mihai G. Netea, Craig E. Wheelock, Keith M. Channon, Mikael Rydén, Irina A. Udalova, Ricardo Carnicer, Robin P. Choudhury
doi : 10.1161/CIRCULATIONAHA.120.046464
Circulation. 2021;144:961–982
Cardiovascular risk in diabetes remains elevated despite glucose-lowering therapies. We hypothesized that hyperglycemia induces trained immunity in macrophages, promoting persistent proatherogenic characteristics.
Coronary Artery Anomalies
Francesco Gentile, Vincenzo Castiglione, Raffaele De Caterina
doi : 10.1161/CIRCULATIONAHA.121.055347
Circulation. 2021;144:983–996
Coronary artery anomalies (CAAs) are a group of congenital conditions characterized by abnormal origin or course of any of the 3 main epicardial coronary arteries. Although CAAs have been identified as a common underlying condition in young athletes with sudden cardiac death, the widespread use of invasive and noninvasive coronary imaging has led to increased recognition of CAAs among adults. CAAS are often discovered as an incidental finding during the diagnostic workup for ischemic heart disease. The clinical correlates and prognostic implication of CAAs remain poorly understood in this context, and guideline-recommended therapeutic choices are supported by a low level of scientific evidence. Several studies have examined whether assessment of CAA-related myocardial ischemia can improve risk stratification in these patients, suggesting that multimodality imaging and functional tests may be key in the management of CAAs. The aim of this review is to outline definitions, classification, and epidemiology of the most relevant CAAs, highlighting recent advances and the potential impact of multimodality evaluation, and to discuss current therapeutic opportunities.
Increasing Burnout Could Have Dire Effects on the Cardiovascular Workforce After the Pandemic
Bridget M. Kuehn
doi : 10.1161/CIRCULATIONAHA.121.056977
Circulation. 2021;144:997–999
Adrenergic-Thyroid Hormone Interactions Drive Postnatal Thermogenesis and Loss of Mammalian Heart Regenerative Capacity
Alexander Y. Payumo, Xi Chen, Kentaro Hirose, Xiaoxin Chen, Alison Hoang, Sheamin Khyeam, Hongyao Yu, Jiajia Wang, Qing Chen, Nevan Powers, Li Chen, Rachel B. Bigley, Jonathan Lovas, Guang Hu, Guo N. Huang
doi : 10.1161/CIRCULATIONAHA.121.054846
Circulation. 2021;144:1000–1003
Letter by Matta et al Regarding Article, “Coronary Optical Coherence Tomography and Cardiac Magnetic Resonance Imaging to Determine Underlying Causes of Myocardial Infarction With Nonobstructive Coronary Arteries in Women”
Anthony Matta, Meyer Elbaz, Jerome Roncalli
doi : 10.1161/CIRCULATIONAHA.120.053041
Circulation. 2021;144:e204
Letter by Nguyen et al Regarding Article, “Coronary Optical Coherence Tomography and Cardiac Magnetic Resonance Imaging to Determine Underlying Causes of Myocardial Infarction With Nonobstructive Coronary Arteries in Women”
Thanh Ha Nguyen, Gao-Jing Ong, John D. Horowitz
doi : 10.1161/CIRCULATIONAHA.121.053409
Circulation. 2021;144:e205
Letter by Allard-Ratick et al Regarding Article, “Coronary Optical Coherence Tomography and Cardiac Magnetic Resonance Imaging to Determine Underlying Causes of Myocardial Infarction With Nonobstructive Coronary Arteries in Women”
Marc P. Allard-Ratick, Cian P. McCarthy, Ik-Kyung Jang
doi : 10.1161/CIRCULATIONAHA.120.053480
Circulation. 2021;144:e206
Letter by Hamilton et al Regarding Article, “Coronary Optical Coherence Tomography and Cardiac Magnetic Resonance Imaging to Determine Underlying Causes of Myocardial Infarction With Nonobstructive Coronary Arteries in Women”
Garry W. Hamilton, Sean Tan, Jamie Layland
doi : 10.1161/CIRCULATIONAHA.121.054834
Circulation. 2021;144:e207–e208
Response by Reynolds et al to Letters Regarding Article, “Coronary Optical Coherence Tomography and Cardiac Magnetic Resonance Imaging to Determine Underlying Causes of Myocardial Infarction With Nonobstructive Coronary Arteries in Women”
Harmony R. Reynolds, Raymond Y. Kwong, Akiko Maehara, Nathaniel R. Smilowitz
doi : 10.1161/CIRCULATIONAHA.121.055516
Circulation. 2021;144:e209–e210
Correction to: Therapeutic Inhibition of Acid Sensing Ion Channel 1a Recovers Heart Function After Ischemia-Reperfusion Injury
doi : 10.1161/CIR.0000000000001020
Circulation. 2021;144:e211
Correction to: Letter by Ren et al Regarding Article, “Acute Heart Failure in Multisystem Inflammatory Syndrome in Children in the Context of Global SARS-CoV-2 Pandemic”
doi : 10.1161/CIR.0000000000001022
Circulation. 2021;144:e212
Correction to: Selective Stimulation of Cardiac Lymphangiogenesis Reduces Myocardial Edema and Fibrosis Leading to Improved Cardiac Function Following Myocardial Infarction
doi : 10.1161/CIR.0000000000001023
Circulation. 2021;144:e213
