Diemer E.W.a · Hudson J.I.b,c · Javaras K.N.b,c
doi : 10.1159/000517104
Psychother Psychosom 2021;90:289–298
Wang J.a · Cosci F.b,c,d
doi : 10.1159/000516031
Psychother Psychosom 2021;90:299–307
A clear picture of neonatal withdrawal signs due to in utero selective serotonin reuptake inhibitor (SSRI) exposure and its consequences is still missing.
Cosci F.a,b · Fava G.A.c
doi : 10.1159/000517518
Psychother Psychosom 2021;90:308–317
Depressive and anxiety disorders are frequently associated. Depression may be a complication of anxiety and anxiety can complicate depression. The nature of their relationship has been a source of controversy. Reviews generally base their conclusions on randomized controlled trials and meta-analyses that refer to the average patient and often clash with the variety of clinical presentations that may occur when anxiety and depression coexist. The aim of this review was to examine the literature according to profiling of subgroups of patients based on clinimetric criteria, in line with the recently developed concept of medicine-based evidence. We critically reviewed the literature pertaining to the specific presentations of anxiety and depression, outlining the advantages and disadvantages of each treatment approach. The following prototypic cases were presented: depression secondary to an active anxiety disorder, depression in patients with anxiety disorders under treatment, anxious depression, anxiety as a residual component of depression, and demoralization secondary to anxiety disorder. We argue that the selection of treatment when anxiety and depression coexist should take into account the modalities of presentation and be filtered by clinical judgment. Very different indications may ensue when the literature is examined according to this perspective.
Wilkinson S.T.a,b · Rhee T.G.a · Joormann J.c · Webler R.d · Ortiz Lopez M.e · Kitay B.a,f · Fasula M.a · Elder C.a · Fenton L.a · Sanacora G.a,b
doi : 10.1159/000517074
Psychother Psychosom 2021;90:318–327
Ketamine has emerged as a rapid-acting antidepressant. While ongoing treatment can prevent relapse, concerns exist regarding long-term exposure.
Schmid C.a · Hansen K.a · Kröner-Borowik T.a · Steil R.a
doi : 10.1159/000512757
Psychother Psychosom 2021;90:328–340
Both imagery rescripting and imaginal exposure have been proven to be effective in the treatment of chronic nightmares when compared to a waitlist condition. Little is known about their comparative efficacy and their efficacy compared to an active control.
Marchant N.L.a · Barnhofer T.b,c · Coueron R.d,e · Wirth M.f,g · Lutz A.h · Arenaza-Urquijo E.M.i,j,k,l · Collette F.m · Poisnel G.i · Demnitz-King H.a · Schild A.-K.n · Coll-Padros N.o · Delphin-Combe F.p · Whitfield T.a · Schlosser M.a · Gonneaud J.i · Asselineau J.d,e · Walker Z.a,q · Krolak-Salmon P.p · Molinuevo J.L.j,k,l,o · Frison E.d,e · Chételat G.i · Jessen F.n,r,s · Klimecki O.M.t,u · The Medit-Ageing Research Group
doi : 10.1159/000515669
Psychother Psychosom 2021;90:341–350
Older adults experiencing subjective cognitive decline (SCD) have a heightened risk of developing dementia and frequently experience subclinical anxiety, which is itself associated with dementia risk.
Käll A.a · Bäck M.a · Welin C.a · Åman H.a · Bjerkander R.a · Wänman M.a · Lindegaard T.a · Berg M.a · Moche H.a · Shafran R.b · Andersson G.a,c,d
doi : 10.1159/000516989
Psychother Psychosom 2021;90:351–358
Chronic loneliness has been linked to many adverse outcomes, including mental health problems. Psychological treatment of loneliness can be effective, but the evidence base is limited.
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