Neurology

Kerleroux, Basile MD*; Benzakoun, Joseph MD*; Janot, Kevin MD; Dargazanli, Cyril MD; Eraya, Dimitri Daly MD; Ben Hassen, Wagih MD; Zhu, Francois MD; Gory, Benjamin MD, PhD; Hak, Jean-Francois MD; Perot, Charline MD; Detraz, Lili MD; Bourcier, Romain MD, PhD; Aymeric, Rouchaud MD, PhD; Forestier, Geraud MD; Marnat, Gaultier MD; Gariel, Florent MD; Mordasini, Pasquale MD; Seners, Pierre MD, PhD; Turc, Guillaume MD, PhD; Kaesmacher, Johannes MD; Oppenheim, Catherine MD; Naggara, Olivier MD, PhD; Boulouis, Gregoire MD; on behalf of the JENI Research Collaborative; on behalf of the JENI Research Collaborative; Fischer, Urs MD, PhD; Gralla, Jan MD, PhD; Mosimann, Pascal J MD; Arnold, Marcel MD, PhD; Meinel, Thomas R MD; Costalat, Vincent MD, PhD; Benali, Amel MD; Derraz, Imad MD; Lefevre, Pierre-Henri MD; Gascou, Gregory MD; Riquelme, Carlos MD; Bonafe, Alain MD, PhD; Le Bars, Emmanuelle MD; Moynier, Marinette MD; Barreau, Xavier MD; Berge, Jerome MD; Menegon, Patrice MD; Tourdias, Thomas MD, PhD; Lucas, Ludovic MD; Sibon, Igor MD, PhD; Saleme, Suzanna MD; Mounayer, Charbel MD, PhD; Girard, Nadine MD, PhD; Bartoli, Jean-Michel MD, PhD; Brunel, Herve MD; Testud, Benoit MD; Puech, Basile MD; Laksiri, Nadia MD; Robinet, Emmanuelle MD; Pelletier, Jean MD, PhD; Herbreteau, Denis MD, PhD; Bibi, Richard MD; Narata, Ana-Paula MD, PhD; Boustia, Fakhreddine MD; Maldonado, Igor MD, PhD; Cottier, Jean- Philippe MD, PhD; Gaudron, Marie MD; Annan, Mariam MD; Meder, Jean-Francois MD, PhD; Trystram, Denis MD; Rodriguez, Christine MD; Edjlali, Myriam MD, PhD; Desal, Hubert MD, PhD; Daumasduport, Benjamin MD; Lallinec, Vincent MD; Lenoble, Cedric MD; Alexandre, Pierre-Louis MD; Bracard, Serge MD, PhD; Anxionnat, Rene MD, PhD; Degrelle, Anne-Laure MD; Tonnelet, Romain MD; Lao, Liang MD; Richard, Sebastien MD, PhD; Humbertjean, Lisa MD; Mione, Gioia MD; Labour, Jean Christophe MD

doi : 10.1212/WNL.0000000000012863

Volume 97(20), 16 November 2021, p e1975-e1985

Individualized patient selection for mechanical thrombectomy (MT) in patients with acute ischemic stroke (AIS) and large ischemic core (LIC) at baseline is an unmet need. We tested the hypothesis that assessing the functional relevance of both infarcted and hypoperfused brain tissue would improve the selection framework of patients with LIC for MT.

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Trends in Mortality From Parkinson Disease in the United States, 1999-2019

Rong, Shuang MD, PhD; Xu, Guifeng MD, PhD; Liu, Buyun MD, PhD; Sun, Yangbo MD, PhD; Snetselaar, Linda G. PhD; Wallace, Robert B. MD; Li, Benchao PhD; Liao, Jingling PhD; Bao, Wei MD, PhD

doi : 10.1212/WNL.0000000000012826

Volume 97(20), 16 November 2021, p e1986-e1993

The mortality from Parkinson disease (PD) and its long-term trends in the United States in recent decades remains unknown. This study aimed to describe the trends in PD mortality in the United States from 1999 to 2019.

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Preoperative REM Sleep Behavior Disorder and Subthalamic Nucleus Deep Brain Stimulation Outcome in Parkinson Disease 1 Year After Surgery

Besse-Pinot, Elsa MD; Pereira, Bruno PhD; Durif, Franck MD, PhD; Fantini, Maria Livia MD, PhD; Durand, Elodie PhD; Debilly, Berengere MD; Derost, Philippe MD; Moreau, Caroline MD, Ph; Hainque, Elodie MD, PhD; Rouaud, Tiphaine MD; Eusebio, Alexandre MD, PhD; Benatru, Isabelle MD; Drapier, Sophie MD; Guehl, Dominique MD, PhD; Rascol, Olivier MD, PhD; Maltete, David MD, PhD; Lagha-Boukbiza, Ouhaid MD; Giordana, Caroline MD; Tir, Melissa MD; Thobois, Stephane MD, PhD; Hopes, Lucie MD; Hubsch, Cecile MD, PhD; Jarraya, Bechir MD, Ph; Rolland, Anne-Sophie PhD; Corvol, Jean-Christophe MD, PhD; Devos, David MD, PhD; Marques, Ana MD, PhD; on behalf of the Predistim Study Group; on behalf of the Predistim Study Group; Moreau, Dr. Caroline; Defebvre, Pr. Luc; Carriere, Dr. Nicolas; Grolez, Dr. Guillaume; Baille, Dr. Gillaume; Kreisler, Dr.; Jean-Pierre Pruvo, Pr.; Leclerc, Pr.; Lopes, Dr. Renaud; Viard, Dr. Romain; Kuchcinski, Dr. Gregory; Dumont, Mr. Julien; Dujardin, Pr. Kathy; Delliaux, Mme. M; Brion, Mme. M; Touzet, Dr. Gustavo; Reyns, Pr. Nicolas; Delval, Pr. Arnaud; Santraine, Mme. Valerie; Pleuvret, Mme. Marie; Dautrevaux, Mme. Nolwen; Laugeais, Mr. Victor; Ouk, Thavarak; Potey, Camille; Leclercq, Celine; Gers, Elise; Duhamel, Alain; Djemmane, Lynda; Duflot, Florence; Corvol, Marie-Vidailhet, Jean-Christophe; Hainque, Elodie; Welter, Marie-Laure; Lacomblez, Lucette; Grabli, David; Roze, Emmanuel; Worbe, Yulia; Delorme, Cecile; You, Hana; Ihle, Jonas; GuimeraesCosta, Raquel; CormierDequaire, Florence; Meneret, Aurelie; Hartmann, Andreas; Mariani, Louise-Laure; Lehericy, Stephane; Czernecki, Virginie; Pineau, Fanny; Bozon, Frederique; Huiban, Camille; Benchetrit, Eve; Karachi, Carine; Navarro, Soledad; Cornu, Philippe; Welaratne, Arlette; Mantisi, Lise; Jarry, Nathalie; Aix, Sophie; Lefort, Carine; Rouaud, Dr. Tiphaine; Damier, Pr. Philippe; Derkinderen, Pr. Pascal; Anne-Gaelle Corbille, Dr.; CalvierAuffray, Dr. Elisabeth; Rocher, Laetitia; Deruet, Anne-Laure; Sylvie, Dr. Raoul; Vincent, Dr. Roualdes; Severine, Le Dily; Marques, Dr. Ana; Debilly, Dr. Berangere; Durif, Pr. Franck; Derost, Dr. Philippe; Beal, Dr. Charlotte; Chassain, Carine; Delaby, Laure; Vidal, Tiphaine; Lemaire, Pr. jean Jeacques; Rieu, Isabelle; Durand, Elodie; Sophie, Dr. Drapier; Leh, Dr. Frederique; Bonnet, Dr. Alexandre; Verin, Pr. Marc; Jean-Christophe Ferre, Dr.; Houvenaghel, Jean Francois; Haegelen, Pr. Claire; Kestens, Francoise; ory, Solenn; Girodana, Dr. Caroline; Marse, Dr. Claire; Mondot, Dr. Lydiane; Giordana, Dr. Bruno; Kardous, Dr. Robin; Bailet, Bernadette; Joly, Heloise; Fontaine, Dr. Denys; Leplus, Dr. Aurelie; Faustini, Amelie; Ferrier, Vanessa; Burbaud, Pr. Pierre; DamonPerriere, Dr. Nathalie; Meissner, Pr. Wassilios; Tison, Pr. Francois; Bannier, Dr. Stephanie; Krim, Dr. Elsa; Guehl, Pr. Dominique; Molinier-Blossier, Dr. Sandrine; Ollivier, Dr. Morgan; Lacoste, Dr. Marion; Auzou, Nicolas; Bonnet, Marie; Cuny, Pr. Emmanuel; Engelhardt, Dr. Julien; Branchard, Olivier; Huet, Clotilde; Blanchard, Julie; Eusebio, Pr. Alexandre; Jean-Philippe Azulay, Pr.; Witjas, Dr. Tatiana; Fluchere, Dr. Frederique; Grimaldi, Dr. Stephan; Girard, Pr. Nadine; Benchetrit, Eve; Delfini, Marie; Carron, Dr. Romain; Regis, Pr. Jean; Spatola, Dr. Giorgio; Magnaudet, Camille; Solene, Dr. Ansquer; Isabelle, Dr. Benatru; Olivier, Dr. Colin; Jean Luc, Pr. Houeto; Remy, Pr. Guillevin; Anne, Fradet; Manssouri, Anziza; Sophie, Blondeau; Philippe, Dr. Richard; Philippe, Dr. Cam; Philippe, Dr. Page; Benoit, Pr. Bataille; Emilie, Rabois; Annie, Guillemain; Maltete, Pr. David; Lefaucheur, Dr. Romain; Fetter, Dr. Damien; Magne, Dr. Nicolas; Bioux, Sandrine; Loubeyre, Maud; Bliaux, Evangeline; Pouliquen, Dorothee; Derrey, Pr. Stephane; Vernon, Mme. Linda; Ziegler, Dr. Frederic; Olivier, Pr. Rascol; Brefel Courbon, Dr. Christine; Ory Magne, Dr. Fabienne; Simonetta Moreau, Dr. Marion; Arbus, Pr. Christophe; Bonneville, Pr. Fabrice; Albert Lotterie, Dr. Jean; Sarrail, Marion; Chaynes, Pr. Patrick; Caire, Pr. Francois; Harroch, Estelle; Anheim, Pr. Mathieu; LaghaBoukbiza, Dr. Ouhaid; Tranchant, Pr. Christine; Gebus, Dr. Odile; Montaut, Dr. Solveig; Kremer, Dr. Stephane; Longato, Nadine; Phillips, Clelie; Voirin, Dr. Jimmy; Marie des Neiges Santin, Dr.; Chaussemy, Dr. Dominique; Mengin, Dr. Amaury; Krystkowiak, Pr. Pierre; Tir, Dr. Melissa; Jean-Marc Constans, Pr.; Wannepain, Sandrine; Seling, Audrey; Lefranc, Dr. Michel; Blin, Stephanie; Schuler, Beatrice; Thobois, Pr. Stephane; Danaila, Dr. Teodor; Laurencin, Dr. Chloe; Berthezene, Pr. Yves; Ameli, Dr. Roxana; Klinger, Helene; Polo, Dr. Gustavo; Simon, Dr. Emile; Mertens, Dr. Patrick; Nunes, A; Metereau, Elise; Hopes, Dr. Lucie Dr; Schmitt, Emmanuelle; Meyer, Mylene; Dillier, Celine; Colnat, Pr. Sophie; Chatelain, Anne; Philippe Brandel, Dr. Jean-; Hubsch, Dr. Cecile; Karsenti, Dr. Patte; Lebouteux, Dr. Marie; Ziegler, Dr. Marc; Delmaire, Dr. Christine; Savatowky, Dr. Julien; Vrillac, Juliette; Nakache, Claire; D'Hardemare, Dr. Vincent; Belamri, Lhaouas; Bourdain, Dr. Frederique; Afanassiev, Dr. Vadim; Graveleau, Dr. Philippe; Decrocq, Dr. Camille; Boulin, Dr. Anne; Dupuy, V, Elodie; Gardel, Dr. Berenice; Jarraya, Pr. Bechir; Lopez, Delphine; Fruit, Christophe; Gay, David; Bonice, Robin; El Mountassir, Fouzia; Fischer, Clara; Mangin, Jean-Francois; Chupin, Marie; Cointepas, Yann; Accart, Bertrand; Gele, Patrick; Fievet, Florine; Chabel, Matthieu; Derenaucourt, Virginie; Facon, Loic; Njosse, Yanick Tchantchou; Deplanque, Dominique

doi : 10.1212/WNL.0000000000012862

Volume 97(20), 16 November 2021, p e1994-e2006

To determine whether patients with Parkinson disease (PD) eligible for subthalamic nucleus deep brain stimulation (STN-DBS) with probable REM sleep behavior disorder (RBD) preoperatively could be more at risk of poorer motor, nonmotor, and quality of life outcomes 12 months after surgery compared to those without RBD.

خرید پکیج و مشاهده آنلاین مقاله

Association of Age at Onset With Gray Matter Volume and White Matter Microstructural Abnormalities in People With Multiple Sclerosis

Bonacchi, Raffaello MD; Meani, Alessandro MSc; Pagani, Elisabetta MSc; Marchesi, Olga MSc; Falini, Andrea MD, PhD; Filippi, Massimo MD; Rocca, Maria A. MD

doi : 10.1212/WNL.0000000000012869

Volume 97(20), 16 November 2021, p e2007-e2019

To investigate whether age at onset influences brain gray matter volume (GMV) and white matter (WM) microstructural abnormalities in adult patients with multiple sclerosis (MS), given its influence on clinical phenotype and disease course.

خرید پکیج و مشاهده آنلاین مقاله

Association Between Cognitive Trajectories and Disability Progression in Patients With Relapsing-Remitting Multiple Sclerosis

Merlo, Daniel PhD; Stankovich, Jim PhD; Bai, Claire MD; Kalincik, Tomas PhD, FRACP; Zhu, Chao PhD; Gresle, Melissa PhD; Lechner-Scott, Jeannette PhD, FRACP; Kilpatrick, Trevor PhD, FRACP; Barnett, Michael PhD, FRACP; Taylor, Bruce PhD, FRACP; Darby, David PhD, FRACP; Butzkueven, Helmut PhD, FRACP*; Van der Walt, Anneke PhD, FRACP*

doi : 10.1212/WNL.0000000000012850

Volume 97(20), 16 November 2021, p e2020-e2031

Longitudinal cognitive trajectories in multiple sclerosis are heterogeneous and difficult to measure. We aimed to identify discrete longitudinal reaction time trajectories in relapsing-remitting multiple sclerosis using a computerized cognitive battery and to assess the association between trajectories of reaction time and disability progression.

خرید پکیج و مشاهده آنلاین مقاله

Teaching the Neurologic Examination: A Prospective Controlled Study to Compare a Blended Learning Approach With Face-to-Face Instruction

Bornkamm, Katharina MD; Koch, Cora MD; Dietterle, Jorg; Steiert, Marius MD; Fleig, Andreas PhD; Weiller, Cornelius MD; Brich, Jochen MD

doi : 10.1212/WNL.0000000000012851

Volume 97(20), 16 November 2021, p e2032-e2038

To compare a blended learning approach with traditional face-to-face instruction in terms of their individual effectiveness in imparting neurologic examination (NE) skills in medical students.

خرید پکیج و مشاهده آنلاین مقاله

Influence of Research Continuity on Physician-Scientists' Career Success

Brownrout, Jenna BA; Norato, Gina ScM; Bensken, Wyatt BS; Squirewell, Catherine BS; Gordon, Taylor BS; Heiss, John MD; Nath, Avindra MD; Khan, Omar I. MD

doi : 10.1212/WNL.0000000000012867

Volume 97(20), 16 November 2021, p e2039-e2045

خرید پکیج و مشاهده آنلاین مقاله

What Is the Role of Potassium Channels in Ataxia?

Benarroch, Eduardo MD

doi : 10.1212/WNL.0000000000012870

Volume 97(20), 16 November 2021, p 938-941

خرید پکیج و مشاهده آنلاین مقاله

Dopaminergic Therapy for Motor Symptoms in Early Parkinson Disease Practice Guideline Summary: A Report of the AAN Guideline Subcommittee

Pringsheim, Tamara MD; Day, Gregory S. MD, MSc; Smith, Don B. MD; Rae-Grant, Alex MD; Licking, Nicole DO; Armstrong, Melissa J. MD; de Bie, Rob M.A. MD, PhD; Roze, Emmanuel MD, PhD; Miyasaki, Janis M. MD; Hauser, Robert A. MD, MBA; Espay, Alberto J. MD; Martello, Justin P. MD; Gurwell, Julie A. PhD, PA-C; Billinghurst, Lori MD, MSc; Sullivan, Kelly PhD; Fitts, Michael S.; Cothros, Nicholas MD, PhD; Hall, Deborah A. MD, PhD; Rafferty, Miriam DPT, PhD; Hagerbrant, Lynn; Hastings, Tara MA; O'Brien, Mary Dolan MLIS; Silsbee, Heather; Gronseth, Gary MD; Lang, Anthony E. MD; on behalf of the Guideline Subcommittee of the AAN; on behalf of the Guideline Subcommittee of the AAN; Pringsheim, Tamara MD; Day, Gregory S. MD, MSc; Smith, DonB. MD; Rae-Grant, Alex MD; Licking, Nicole DO; Armstrong, Melissa J. MD; de Bie, Rob M. A. MD, PhD; Roze, Emmanuel MD, PhD; Miyasaki, Janis M. MD; A.Hauser, Robert MD, MBA; Espay, Alberto J. MD; Martello, Justin P. MD; Gurwell, Julie PhD, PA-C; Billinghurst, Lori MD, MS; Sullivan, Kelly PhD; Fitts, Michael S.; Cothros, Nicholas MD, PhD; Hall, Deborah A. MD, PhD; Rafferty, Miriam DPT, Ph; Hagerbrant, Lynn; Hastings, Tara MA; O'Brien, Mary Dolan MLIS; Silsbee, Heather; Gronseth, Gary MD; Lang, Anthony E. MD

doi : 10.1212/WNL.0000000000012868

Volume 97(20), 16 November 2021, p 942-957

To review the current evidence on the options available for initiating dopaminergic treatment of motor symptoms in early-stage Parkinson disease and provide recommendations to clinicians.

خرید پکیج و مشاهده آنلاین مقاله

Clinical Reasoning: A 59-Year-Old Man With Progressive Proximal Weakness Since Childhood

Davalos, Long MD; Janecek, Jacqueline MD; Fudym, Yelena DO; McKeever, Paul MD; Callaghan, Brian C. MD

doi : 10.1212/WNL.0000000000012488

Volume 97(20), 16 November 2021, p 958-963

خرید پکیج و مشاهده آنلاین مقاله

Emerging Subspecialties in Neurology: Becoming an Editor-In-Chief

Michaelson, Nara Miriam MD; Aaroe, Ashley Elimar MD; Lewis, Steven L. MD; Safdieh, Joseph E. MD

doi : 10.1212/WNL.0000000000012609

Volume 97(20), 16 November 2021, p e2046-e2049

An Editor-in-Chief leads the editorial team and supervises the daily tasks required to prepare articles for publication while managing the overall content and style of the journal. To become Editor-in-Chief, one must have dedicated work ethic, close attention to detail, passion for the editorial process, and a keen ability to work with and give feedback to section editors and authors. For this article, we interviewed Dr. Steven L. Lewis, Dr. Joseph E. Safdieh, and Dr. S. Andrew Josephson about their collective experience of becoming Editors-in-Chief of Continuum, Neurology Today, and JAMA Neurology, respectively. We have compiled tips for aspiring medical writers and editors, based on their expert advice, to guide trainees in this potential career path.

خرید پکیج و مشاهده آنلاین مقاله

Teaching NeuroImage: Dorsal Medullary Lesions in Juvenile-Onset Alexander Disease

Sollee, John BS; Waldman, Amy MD, MSCE

doi : 10.1212/WNL.0000000000012411

Volume 97(20), 16 November 2021, p e2050-e2051

خرید پکیج و مشاهده آنلاین مقاله

Teaching Video NeuroImage: Clues in Myoclonus Evaluation: When to Consider Sialidosis

Velez Gomez, Beatriz MD; Jesus, Silvia MD, PhD; Macias-Garcia, Daniel MD; Lechon, Beatriz MD; Mir, Pablo MD, PhD

doi : 10.1212/WNL.0000000000012464

Volume 97(20), 16 November 2021, p e2052-e2053

خرید پکیج و مشاهده آنلاین مقاله

Editors' Note: Long-term Effects of Cholinesterase Inhibitors on Cognitive Decline and Mortality

Ganesh, Aravind MD, DPhil, FRCPC; Galetta, Steven MD

doi : 10.1212/WNL.0000000000012871

Volume 97(20), 16 November 2021, p 964

خرید پکیج و مشاهده آنلاین مقاله

Reader Response: Long-term Effects of Cholinesterase Inhibitors on Cognitive Decline and Mortality

Kuschpel, Maxim S.

doi : 10.1212/WNL.0000000000012872

Volume 97(20), 16 November 2021, p 964-965

خرید پکیج و مشاهده آنلاین مقاله

Author Response: Long-term Effects of Cholinesterase Inhibitors on Cognitive Decline and Mortality

Xu, Hong; Garcia-Ptacek, Sara; Eriksdotter, Maria

doi : 10.1212/WNL.0000000000012874

Volume 97(20), 16 November 2021, p 965

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Editors' Note: Kidney Function, Kidney Function Decline, and the Risk of Dementia in Older Adults

Ganesh, Aravind MD, DPhil, FRCPC; Galetta, Steven MD

doi : 10.1212/WNL.0000000000012873

Volume 97(20), 16 November 2021, p 965-966

خرید پکیج و مشاهده آنلاین مقاله

Reader Response: Kidney Function, Kidney Function Decline, and the Risk of Dementia in Older Adults

Fischereder, Michael

doi : 10.1212/WNL.0000000000012875

Volume 97(20), 16 November 2021, p 966-967

خرید پکیج و مشاهده آنلاین مقاله

Author Response: Kidney Function, Kidney Function Decline, and the Risk of Dementia in Older Adults

Xu, Hong; Garcia-Ptacek, Sara; Lindholm, Bengt; Eriksdotter, Maria; Carrero, Juan Jesus

doi : 10.1212/WNL.0000000000012876

Volume 97(20), 16 November 2021, p 967

خرید پکیج و مشاهده آنلاین مقاله

Imaging of the Vulnerable Carotid Plaque: Role of Imaging Techniques and a Research Agenda

doi : 10.1212/WNL.0000000000012758

Volume 97(20), 16 November 2021, p 968

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