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Training future specialists in Obstetrics and Gynecology: Is harmonization possible in Europe?
Ganesh Acharya,Irene Sterpu,Lotta Herling
doi : 10.1111/aogs.14283
Volume 100, Issue 11 p. 1939-1940
Ultrasound vs routine care before instrumental vaginal delivery: A systematic review and meta-analysis
Ilenia Mappa,Silvio Tartaglia,Pavjola Maqina,Alexander Makatsariya,Tullio Ghi,Giuseppe Rizzo,Francesco D’Antonio
doi : 10.1111/aogs.14236
Volume 100, Issue 11 p. 1941-1948
The objective was to report the role of intrapartum ultrasound examination in affecting maternal and perinatal outcome in women undergoing instrumental vaginal delivery.
Reproductive and pregnancy outcomes following embryo transfer in women with previous cesarean section: A systematic review and meta-analysis
Gaetano Riemma,Pasquale De Franciscis,Marco Torella,Giuliana Narciso,Marco La Verde,Maddalena Morlando,Luigi Cobellis,Nicola Colacurci
doi : 10.1111/aogs.14239
Volume 100, Issue 11 p. 1949-1960
Cesarean section affects subsequent spontaneous pregnancies because of implantation issues. However, its impact on post-embryo transfer pregnancies is still debated. This review aimed to evaluate the impact of a previous cesarean section on fertility and pregnancy outcomes of women undergoing fresh or frozen embryo transfer.
Can time to menopause be predicted?
Tom G. Tanbo,Peter Z. Fedorcsak
doi : 10.1111/aogs.14253
Volume 100, Issue 11 p. 1961-1968
Menopause represents the definite end of a woman’s reproductive life and the onset of a persistent hypoestrogenic state. This postmenopausal period will for most women last several decades. Although mean menopausal age seems to have increased somewhat during the last century, there is a significant individual variation in age at natural menopause. With efficient contraception, women of reproductive age can now, to some extent, choose when they want to have children. As a consequence of this and other sociodemographic changes, age at first birth has increased significantly over the last 50 years. It is well documented that long before a woman enters the menopausal transition and subsequent menopause, fertility declines and finally ceases. Being able to predict when a woman will enter menopause would therefore, from a reproductive perspective, be of major interest. Several sociodemographic, morphometric, and endocrine factors are associated with age at menopause or time to menopause. Unfortunately the sensitivity and specificity of these in predicting time to or age at menopause are low. Therefore, with the exception of anti-Müllerian hormone measurements, either alone or in combination with chronological age close to menopause, there are as of now no reliable ways of predicting when a woman will enter menopause.
Temporal trends in obstetric anal sphincter injury from the first vaginal delivery in Austria, Canada, Norway, and Sweden
Maria Gyhagen,Marie Ellström Engh,Heinrich Husslein,Heinz Koelbl,Ida E. K. Nilsson,Jane Schulz,Adrian Wagg,Ian Milsom
doi : 10.1111/aogs.14244
Volume 100, Issue 11 p. 1969-1976
Obstetric anal sphincter injuries (OASI) are severe complications that can cause considerable short- and long-term morbidity. Austria, Canada, Norway, and Sweden have similar socio-economic characteristics, and all four countries have access to national birth registers. In this study, we hypothesized that the incidence of OASI should be very similar for different obstetric scenarios in these four countries. Therefore, the aim was to compare the incidence of OASI in these four countries in primiparous women, with spontaneous or instrumental delivery (vacuum or forceps), and in women with a first vaginal birth after cesarean section (VBAC).
Outpatient vs inpatient Foley catheter induction of labor in multiparas with unripe cervixes: A randomized trial
Mukhri Hamdan,Shuib Shuhaina,Jesrine Gek Shan Hong,Narayanan Vallikkannu,Syeda Nureena Zaidi,Yi Pin Tan,Peng Chiong Tan
doi : 10.1111/aogs.14247
Volume 100, Issue 11 p. 1977-1985
Multiparous labor inductions are typically successful, and the process can be rapid, starting from a ripened cervix with a predictable response to amniotomy and oxytocin infusion. Outpatient Foley catheter labor induction in multiparas with unripe cervixes is a feasible option as the mechanical process of ripening is usually without significant uterine contractions and well tolerated. Labor contractions can be initiated by amniotomy and titrated oxytocin infusion in the hospital for well-timed births during working hours as night birth are associated with adverse events. We sought to evaluate outpatient compared with inpatient Foley catheter induction of labor in multiparas for births during working hours and maternal satisfaction.
Vertical transmission of methicillin-resistant Staphylococcus aureus at delivery and its clinical impact: An observational, prospective cohort study
Jumpei Ogura,Yoshihide Inayama,Naoko Sasamoto,Takahiro Hirayama,Tsutomu Ohara,Mie Sakai,Haruka Suzuki,Koji Yasumoto,Koh Suginami,Koji Yamanoi
doi : 10.1111/aogs.14240
Volume 100, Issue 11 p. 1986-1994
Methicillin-resistant Staphylococcus aureus (MRSA) infection has a significant clinical impact on both pregnant women and neonates. The aim of this study was to assess accurately the vertical transmission rate of MRSA and its clinical impacts on both pregnant mothers and neonates.
Impact of past obstetric history and cervical excision on preterm birth rate
Anna Collins,Tanushree Motiwale,Olivia Barney,Frank Dudbridge,Penelope C. McParland,Esther L. Moss
doi : 10.1111/aogs.14254
Volume 100, Issue 11 p. 1995-2002
To determine the impact on preterm birth (PTB) of a history of large loop excision of the transformation zone (LLETZ)-alone compared with a history of previous preterm birth-alone (PPTB) or a history of both (LLETZ+PPTB). Secondary analyses were performed to evaluate the impact of antenatal interventions, depth of cervical excision, and patient risk factors on PTB rate in each cohort.
Emergency cervical cerclage in twin and singleton pregnancies with 0-mm cervical length or prolapsed membranes
Georgina D. Freegard,Vera Donadono,Lawrence W. M. Impey
doi : 10.1111/aogs.14255
Volume 100, Issue 11 p. 2003-2008
Cervical cerclage is controversial in twin pregnancies, although recent data from the USA supports its use where “physical examination-indicated”. Limited data exist, however, in the extreme situation of 0-mm ultrasound-measured cervical length or even prolapsed membranes. This research compares the success of emergency cervical cerclage in multiple and singleton pregnancies.
Mental health indicators in pregnant women compared with women in the general population during the coronavirus disease 2019 pandemic in Denmark
Elin R. Severinsen,Lise K. A. Kähler,Sofie E. Thomassen,Tibor V. Varga,Line Fich Olsen,Kathrine V. R. Hviid,Nina la Cour Freiesleben,Naja H. Rod,Henriette S. Nielsen
doi : 10.1111/aogs.14258
Volume 100, Issue 11 p. 2009-2018
The coronavirus disease 2019 (COVID-19) pandemic and the associated regulations issued to minimize risk of disease transmission seem to have had an impact on general mental health in most populations, but it may have affected pregnant women even more because of pregnancy-related uncertainties, limited access to healthcare resources, and lack of social support. We aimed to compare the mental health response among pregnant women with that in similarly aged women from the general population during the first wave of the COVID-19 pandemic.
Risk of adverse perinatal outcomes in infants born to mothers with mental health conditions
Signe Heuckendorff,Louise F. Christensen,Kirsten Fonager,Charlotte Overgaard
doi : 10.1111/aogs.14241
Volume 100, Issue 11 p. 2019-2028
Maternal mental health conditions have been shown to affect perinatal outcomes negatively. However, knowledge on the impact of different types and severities of maternal mental health conditions is needed. The objective of this study was to determine the association between maternal mental health status and perinatal health outcomes in the infant.
Perinatal outcome after selective termination in dichorionic twins discordant for congenital anomalies
Mar Bennasar,Júlia Ponce,Ximena Torres,Olga Gómez,Joan Sabrià,Eduard Gratacós,Antoni Borrell,Josep M. Martínez
doi : 10.1111/aogs.14249
Volume 100, Issue 11 p. 2029-2035
Our objective was to evaluate the perinatal outcome of selective termination of dichorionic twin pregnancies with discordant anomalies, according to gestational age at time of procedure.
Non-invasive prenatal diagnosis for translocation carriers—YES please or NO go?
Malgorzata I. Srebniak,Fernanda S. Jehee,Marieke Joosten,Marjan Boter,Walter G. de Valk,Robert van der Helm,Erik A. Sistermans,Els Voorhoeve,Shama Bhola,Mariette J. V. Hoffer,Nicolette den Hollander,Merryn V. E. Macville,Diane Van Opstal
doi : 10.1111/aogs.14256
Volume 100, Issue 11 p. 2036-2043
The presence of an unbalanced familial translocation can be reliably assessed in the cytotrophoblast of chorionic villi. However, carriers of a balanced translocation often decline invasive testing. This study aimed to investigate whether an unbalanced translocation can also be diagnosed in cell free DNA by whole-genome non-invasive prenatal screening (NIPS).
Evaluation of satisfaction with a model of structured contraceptive counseling: Results from the LOWE trial
Niklas Envall,Karin Emtell Iwarsson,Isabella Bizjak,Kristina Gemzell Danielsson,Helena Kopp Kallner
doi : 10.1111/aogs.14243
Volume 100, Issue 11 p. 2044-2052
Intervention trials of structured contraceptive counseling have proved to increase use of long-acting reversible contraceptives (LARCs) and decrease numbers of unintended pregnancies. However, these interventions have not been evaluated from a user perspective. This study aimed to evaluate both healthcare providers’ and participants’ satisfaction with an intervention used in a large trial in Sweden.
Maternal polycystic ovary syndrome and attention deficit hyperactivity disorder in offspring at 3 years of age: Odense Child Cohort
Cilia M. Dalgaard,Marianne S. Andersen,Richard C. Jensen,Pia V. Larsen,Laura G. Find,Henriette Boye,Tina K. Jensen,Niels Bilenberg,Dorte Glintborg
doi : 10.1111/aogs.14259
Volume 100, Issue 11 p. 2053-2065
Previous data suggested a link between maternal polycystic ovary syndrome (PCOS) and offspring attention deficit hyperactivity disorder (ADHD), which could be mediated by higher prenatal androgen exposure.
Uterine leiomyomas in hereditary leiomyomatosis and renal cell cancer (HLRCC) syndrome can be identified through distinct clinical characteristics and typical morphology
Outi Uimari,Anne Ahtikoski,Kati Kämpjärvi,Ralf Butzow,Ilkka Y. Järvelä,Markku Ryynänen,Lauri A. Aaltonen,Pia Vahteristo,Outi Kuismin
doi : 10.1111/aogs.14248
Volume 100, Issue 11 p. 2066-2075
Hereditary leiomyomatosis and renal cell cancer (HLRCC) constitute a tumor susceptibility syndrome caused by germline mutations in the fumarate hydratase (FH) gene. The most common features are leiomyomas of the uterus and the skin. The syndrome includes a predisposition to early-onset, aggressive renal cell cancer. It is important to identify women with HLRCC among other uterine leiomyoma patients in order to direct them to genetic counseling and to identify other affected family members.
A novel method for office aspiration curettage in cases of retained products of conception: A randomized controlled trial
Meir Pomeranz,Nitzan Goren Gepstein,Michal Ovadia,Zvi Klein,Yair Daykan,Ron Schonman,Nissim Arbib
doi : 10.1111/aogs.14245
Volume 100, Issue 11 p. 2076-2081
Missed abortion can be treated with medication or aspiration curettage. A Karman aspiration cannula is another option. We evaluated its success in evacuating retained products of conception (RPOC) based on symptoms, endometrial thickness, endometrial irregularity, and blood flow seen on Doppler ultrasound (indicative of placenta).
Decline in surgeon volume after successful implementation of advanced laparoscopic surgery in gynecology: An undesired side effect?
Fokkedien H. M. P. Tummers,Jasmin Hoebink,Sara R. C. Driessen,Frank Willem Jansen,Andries R. H. Twijnstra
doi : 10.1111/aogs.14242
Volume 100, Issue 11 p. 2082-2090
The implementation of advanced minimally invasive surgical (MIS) techniques has broadened. An extensive body of literature shows that high hospital and surgeon volumes lead to better patient outcomes. However, no information is available regarding volume trends in the post-implementation phase of MIS. This study investigated these trends and poses suggestions to adjust these developments. This knowledge can provide guidance to optimize patient safe performance of new surgical techniques.
Venous thromboembolism in women with ovarian cancer undergoing neoadjuvant chemotherapy prior to cytoreductive surgery: A retrospective study
Samuel G. Oxley,Yaa A. Achampong,Nikola Sambandan,Daniel J. Hughes,Mari Thomas,Michelle Lockley,Adeola Olaitan
doi : 10.1111/aogs.14246
Volume 100, Issue 11 p. 2091-2096
Ovarian cancer is associated with a venous thromboembolism risk of at least 7.2% by 2 years from diagnosis, and although patients undergoing surgery benefit from routine thromboprophylaxis, those undergoing neoadjuvant chemotherapy do not. This study aims to determine the venous thromboembolism incidence in patients with ovarian cancer undergoing neoadjuvant chemotherapy, and explore whether any subset is at higher risk, in order to evaluate whether thromboprophylaxis is justified in some or all of these patients.
SARS-CoV-2 infection in pregnancy in Denmark—characteristics and outcomes after confirmed infection in pregnancy: A nationwide, prospective, population-based cohort study
Anna J. M. Aabakke,Lone Krebs,Tanja G. Petersen,Frank S. Kjeldsen,Giulia Corn,Karen Wøjdemann,Mette H. Ibsen,F. Jonsdottir,Elisabeth Rønneberg,Charlotte S. Andersen,Iben Sundtoft,Tine Clausen,Julie Milbak,Lars Burmester,Birgitte Lindved,Annette Thorsen-Meyer,Mohammed R. Khalil,Birgitte Henriksen,Lisbeth Jønsson,Lise L. T. Andersen,Kamilla K. Karlsen,Monica L. Pedersen,Åse Klemmensen,Marianne Vestgaard,Dorthe Thisted,Manrinder K. Tatla,Line S. Andersen,Anne-Line Brülle,Arense Gulbech,Charlotte B. Andersson,Richard Farlie,Lea Hansen,Lone Hvidman,Anne N. Sørensen,Sidsel L. Rathcke,Katrine H. Rubin,Lone K. Petersen,Jan S. Jørgensen,Lonny Stokholm,Mette Bliddal
doi : 10.1111/aogs.14252
Volume 100, Issue 11 p. 2097-2110
Assessing the risk factors for and consequences of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during pregnancy is essential to guide clinical care. Previous studies on SARS-CoV-2 infection in pregnancy have been among hospitalized patients, which may have exaggerated risk estimates of severe outcomes because all cases of SARS-CoV-2 infection in the pregnant population were not included. The objectives of this study were to identify risk factors for and outcomes after SARS-CoV-2 infection in pregnancy independent of severity of infection in a universally tested population, and to identify risk factors for and outcomes after severe infection requiring hospital admission.
Use of sildenafil and other phosphodiesterase type 5 inhibitors among pregnant women in Scandinavia
Carolyn E. Cesta,Silvia Segovia Chacón,Anders Engeland,Anne Broe,Per Damkier,Kari Furu,Helle Kieler,Pär Karlsson
doi : 10.1111/aogs.14251
Volume 100, Issue 11 p. 2111-2118
For phosphodiesterase type 5 (PDE5) inhibitors, such as sildenafil, the only approved indication in women is for pulmonary arterial hypertension. These drugs are increasingly being proposed and tested for treatment of female infertility and complications in pregnancy. However, the extent of use of PDE5 inhibitors in the general pregnant population over the last decades is unknown. Therefore, we conducted a descriptive cohort study using data from the population health registers in the Scandinavian countries.
Increase of stillbirths and unplanned out-of-hospital births during coronavirus disease 2019 lockdown and the Zagreb earthquake
Mislav Mikuš,Vesna Sokol Karadjole,Držislav Kalafati?,Slavko Oreškovi?,Andrea Šar?evi?
doi : 10.1111/aogs.14250
Volume 100, Issue 11 p. 2119-2120
Professor Emeritus Kåre Molne, Oslo, passed away July 1, 2021, at the age of 88
Sturla H. Eik-Nes,Arne Sunde,Mette Haase Moen
doi : 10.1111/aogs.14273
Volume 100, Issue 11 p. 2121-2122
Editor’s Note: Abu Hashim H, EL Rakhawy M and Abd Elaal I. Randomized comparison of superovulation with letrozole vs clomiphene citrate in an IUI program for women with recently surgically treated minimal to mild endometriosis. Acta Obstetricia et Gynecologica Scandinavica, 2012;91:338–345
doi : 10.1111/aogs.14191
Volume 100, Issue 11 p. 2123-2123
Editor's Note: Abu Hashim H, Ombar O and Abd Elaal I. Intrauterine insemination vs timed intercourse with clomiphene citrate in polycystic ovary syndrome: a randomized controlled trial. Abu Hashim H, Ombar O, Abd Elaal I. Volume 90 Issue 4 Acta Obstetricia et Gynecologica Scandinavica pages: 344–350 First Published online: 03 January 2011
doi : 10.1111/aogs.14193
Volume 100, Issue 11 p. 2124-2124
Editor’s Note: Badawy AM, Elnashar AM, and Mosbah AA. Aromatase inhibitors or gonadotropin-releasing hormone agonists for the management of uterine adenomyosis: a randomized controlled trial. Acta Obstetricia et Gynecologica Scandinavica, 2012;91:489–495
doi : 10.1111/aogs.14192
Volume 100, Issue 11 p. 2125-2125
Editor’s Note: Badawy A, State O and Abdelgawad S. N-Acetyl cysteine and clomiphene citrate for induction of ovulation in polycystic ovary syndrome: a cross-over trial. Acta Obstetricia et Gynecologica Scandinavica, 2007;86:218–222
doi : 10.1111/aogs.14194
Volume 100, Issue 11 p. 2126-2126
Editor’s Note: Badawy A, Shokeir T, Allam AF and Abdelhady H. Pregnancy outcome after ovulation induction with aromatase inhibitors or clomiphene citrate in unexplained infertility. Acta Obstetricia et Gynecologica Scandinavica, 2009; 88:187–191
doi : 10.1111/aogs.14195
Volume 100, Issue 11 p. 2127-2127
