Jessica E. Green,Michael Berk,Amy Loughman,Wolfgang Marx,David Castle,Amelia J. McGuinness,John F. Cryan,Andrew A. Nierenberg,Eugene Athan,Christopher Hair,Felice Jacka
doi : 10.1111/bdi.13124
Volume 23, Issue 7 p. 651-655
Fiona Lobban
doi : 10.1111/bdi.13134
Volume 23, Issue 7 p. 656-658
Ralph Kupka,Anne Duffy,Jan Scott,Jorge Almeida,Vicent Balanzá-Martínez,Boris Birmaher,David J. Bond,Elisa Brietzke,Ines Chendo,Benicio N. Frey,Iria Grande,Danella Hafeman,Tomas Hajek,Manon Hillegers,Marcia Kauer-Sant’Anna,Rodrigo B. Mansur,Afra van der Markt,Robert Post,Mauricio Tohen,Hailey Tremain,Gustavo Vazquez,Eduard Vieta,Lakshmi N. Yatham,Michael Berk,Martin Alda,Flávio Kapczinski
doi : 10.1111/bdi.13105
Volume 23, Issue 7 p. 659-678
Clinical staging is widely used in medicine to map disease progression, inform prognosis, and guide treatment decisions; in psychiatry, however, staging remains a hypothetical construct. To facilitate future research in bipolar disorders (BD), a well-defined nomenclature is needed, especially since diagnosis is often imprecise with blurred boundaries, and a full understanding of pathophysiology is lacking.
Georgia M. Parkin,Michael J. McCarthy,Soe H. Thein,Hillary L. Piccerillo,Nisha Warikoo,Douglas A. Granger,Elizabeth A. Thomas
doi : 10.1111/bdi.13128
Volume 23, Issue 7 p. 679-688
The narrow therapeutic window of lithium medications necessitates frequent serum monitoring, which can be expensive and inconvenient for the patient. Compared to blood, saliva collection is easier, non-invasive, requires less processing, and can be done without the need for trained personnel. This study investigated the utility of longitudinal salivary lithium level monitoring.
Deborah Benevenuto,Kirti Saxena,Gabriel R. Fries,Samira S. Valvassori,Ramandeep Kahlon,Johanna Saxena,Sherin Kurian,Cristian P. Zeni,Iram F. Kazimi,Giselli Scaini,Jair C. Soares,João Quevedo
doi : 10.1111/bdi.13027
Volume 23, Issue 7 p. 689-696
There has been growing scientific evidence in recent years that bipolar disorder (BD) is associated with alterations in the kynurenine (KYN) pathway. However, many of these studies have been limited by their focus on adults. Thus, this preliminary study investigated differences in the peripheral levels of KYN metabolites in children and adolescents with BD, unaffected offspring of parents with BD, and healthy controls (HCs).
Genevieve McPhilemy,Fintan Byrne,Mairead Waldron,Joseph R. Hibbeln,John Davis,Colm McDonald,Brian Hallahan
doi : 10.1111/bdi.13037
Volume 23, Issue 7 p. 697-706
Previous work suggests supplementation with omega-3 polyunsaturated fatty acids (PUFAs) may improve mood symptoms in bipolar disorder (BD) although findings remain unclear. In this study, we assess the efficacy of omega-3 PUFA administration for prophylaxis in BD using a clinical trial design over 52-weeks (ClinicalTrials.gov Identifier: NCT04210804).
Fabiano G. Nery,Wenbin Li,Melissa P. DelBello,Jeffrey A. Welge
doi : 10.1111/bdi.13039
Volume 23, Issue 7 p. 707-714
Previous studies and meta-analyses suggested that N-acetylcysteine (NAC) was superior to placebo in improving depression in bipolar disorder. However, more recent data, including two larger trials, found that NAC was no more effective than placebo. We conducted a meta-analysis to appraise the possible efficacy of NAC in treating bipolar depression.
Mehak Pahwa,Boney Joseph,Nicolas A. Nunez,Gregory D. Jenkins,Colin L. Colby,Kianoush B. Kashani,Marin Veldic,Katherine M. Moore,Hannah K. Betcher,Aysegul Ozerdem,Alfredo B. Cuellar-Barboza,Susan L. McElroy,Joanna M. Biernacka,Mark A. Frye,Balwinder Singh
doi : 10.1111/bdi.13052
Volume 23, Issue 7 p. 715-723
Long-term lithium therapy (LTLT) has been associated with kidney insufficiency in bipolar disorder (BD). We aimed to investigate the risk factors of chronic kidney disease (CKD) development and progression among BD patients receiving LTLT.
Paula Villela Nunes,Camila Nascimento,Beny Lafer
doi : 10.1111/bdi.13108
Volume 23, Issue 7 p. 724-725
Sune Puggaard Vogt Straszek,René E. Nielsen,Zoltan Kovacs,Rasmus W. Licht
doi : 10.1111/bdi.13113
Volume 23, Issue 7 p. 726-727
Balwinder Singh,Jennifer L. Vande Voort,Simon Kung
doi : 10.1111/bdi.13129
Volume 23, Issue 7 p. 728-729
Taro Kishi,Kenji Sakuma,Makoto Okuya,Masashi Ikeda,Nakao Iwata
doi : 10.1111/bdi.13115
Volume 23, Issue 7 p. 730-731
Gordon Parker
doi : 10.1111/bdi.13121
Volume 23, Issue 7 p. 732-732
Holly M. Hendin,Andrew D. Penn
doi : 10.1111/bdi.13095
Volume 23, Issue 7 p. 733-735
Mohsen Khosravi
doi : 10.1111/bdi.13079
Volume 23, Issue 7 p. 736-739
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