دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه
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Methods of Public Health Research — Strengthening Causal Inference from Observational Data
Miguel A. Hernán, M.D., Dr.P.H.
doi : 10.1056/NEJMp2113319
N Engl J Med 2021; 385:1345-1348
The No Surprises Act and Informed Financial Consent
Barak Richman, J.D., Ph.D., Mark Hall, J.D., and Kevin Schulman, M.D.
doi : 10.1056/NEJMp2109971
N Engl J Med 2021; 385:1348-1351
Integrating Research into Community Practice — Toward Increased Diversity in Clinical Trials
Janet Woodcock, M.D., Richardae Araojo, Pharm.D., Twyla Thompson, Pharm.D., and Gary A. Puckrein, Ph.D.
doi : 10.1056/NEJMp2107331
N Engl J Med 2021; 385:1351-1353
Effectiveness of Covid-19 Vaccines in Ambulatory and Inpatient Care Settings
Mark G. Thompson, Ph.D., Edward Stenehjem, M.D., Shaun Grannis, M.D., Sarah W. Ball, Sc.D., Allison L. Naleway, Ph.D., Toan C. Ong, Ph.D., Malini B. DeSilva, M.D., M.P.H., Karthik Natarajan, Ph.D., Catherine H. Bozio, Ph.D., M.P.H., Ned Lewis, M.P.H., Kristin Dascomb, M.D., Ph.D., Brian E. Dixon, M.P.A., Ph.D., Rebecca J. Birch, M.P.H., Stephanie A. Irving, M.H.S., Suchitra Rao, M.D., Elyse Kharbanda, M.D., M.P.H., Jungmi Han, B.S., Sue Reynolds, Ph.D., M.P.H., Kristin Goddard, M.P.H., Nancy Grisel, M.P.P., William F. Fadel, Ph.D., Matthew E. Levy, Ph.D., Jill Ferdinands, Ph.D., Bruce Fireman, M.A., Julie Arndorfer, M.P.H., Nimish R. Valvi, Dr.P.H., Elizabeth A. Rowley, Dr.P.H., Palak Patel, M.B., B.S., M.P.H., Ousseny Zerbo, Ph.D., Eric P. Griggs, M.P.H., Rachael M. Porter, M.P.H., Maria Demarco, Ph.D., Lenee Blanton, M.P.H., Andrea Steffens, M.P.H., Yan Zhuang, Ph.D., Natalie Olson, M.P.H., Michelle Barron, M.D., Patricia Shifflett, R.N., Stephanie J. Schrag, D.Phil., Jennifer R. Verani, M.D., M.P.H., Alicia Fry, M.D., M.P.H., Manjusha Gaglani, M.B., B.S., Eduardo Azziz-Baumgartner, M.D., M.P.H., and Nicola P. Klein, M.D., Ph.D.
doi : 10.1056/NEJMoa2110362
N Engl J Med 2021; 385:1355-1371
There are limited data on the effectiveness of the vaccines against symptomatic coronavirus disease 2019 (Covid-19) currently authorized in the United States with respect to hospitalization, admission to an intensive care unit (ICU), or ambulatory care in an emergency department or urgent care clinic.
Immediate versus Postponed Intervention for Infected Necrotizing Pancreatitis
Lotte Boxhoorn, M.D., Sven M. van Dijk, M.D., Ph.D., Janneke van Grinsven, M.D., Ph.D., Robert C. Verdonk, M.D., Ph.D., Marja A. Boermeester, M.D., Ph.D., Thomas L. Bollen, M.D., Ph.D., Stefan A.W. Bouwense, M.D., Ph.D., Marco J. Bruno, M.D., Ph.D., Vincent C. Cappendijk, M.D., Ph.D., Cornelis H.C. Dejong, M.D., Ph.D., Peter van Duijvendijk, M.D., Ph.D., Casper H.J. van Eijck, M.D., Ph.D., et al., for the Dutch Pancreatitis Study Group*
doi : 10.1056/NEJMoa2100826
N Engl J Med 2021; 385:1372-1381
Infected necrotizing pancreatitis is a potentially lethal disease that is treated with the use of a step-up approach, with catheter drainage often delayed until the infected necrosis is encapsulated. Whether outcomes could be improved by earlier catheter drainage is unknown.
Bamlanivimab plus Etesevimab in Mild or Moderate Covid-19
Michael Dougan, M.D., Ph.D., Ajay Nirula, M.D., Ph.D., Masoud Azizad, M.D., Bharat Mocherla, M.D., Robert L. Gottlieb, M.D., Ph.D., Peter Chen, M.D., Corey Hebert, M.D., Russell Perry, M.D., Joseph Boscia, M.D., Barry Heller, M.D., Jason Morris, M.D., Chad Crystal, M.D., Awawu Igbinadolor, M.D., Gregory Huhn, M.D., M.P.H.T.M., Jose Cardona, M.D., Imad Shawa, M.D., Princy Kumar, M.D., Andrew C. Adams, Ph.D., Jacob Van Naarden, B.S., Kenneth L. Custer, Ph.D., M.B.A., Michael Durante, M.S., Gerard Oakley, M.D., Andrew E. Schade, M.D., Ph.D., Timothy R. Holzer, Ph.D., Philip J. Ebert, Ph.D., Richard E. Higgs, M.S., Nicole L. Kallewaard, Ph.D., Janelle Sabo, Pharm.D., Dipak R. Patel, M.D., Ph.D., Matan C. Dabora, M.D., M.B.A., Paul Klekotka, M.D., Ph.D., Lei Shen, Ph.D., and Daniel M. Skovronsky, M.D., Ph.D. for the BLAZE-1 Investigators*
doi : 10.1056/NEJMoa2102685
N Engl J Med 2021; 385:1382-1392
Patients with underlying medical conditions are at increased risk for severe coronavirus disease 2019 (Covid-19). Whereas vaccine-derived immunity develops over time, neutralizing monoclonal-antibody treatment provides immediate, passive immunity and may limit disease progression and complications.
Protection of BNT162b2 Vaccine Booster against Covid-19 in Israel
Yinon M. Bar-On, M.Sc., Yair Goldberg, Ph.D., Micha Mandel, Ph.D., Omri Bodenheimer, M.Sc., Laurence Freedman, Ph.D., Nir Kalkstein, B.Sc., Barak Mizrahi, M.Sc., Sharon Alroy-Preis, M.D., Nachman Ash, M.D., Ron Milo, Ph.D., and Amit Huppert, Ph.D.
doi : 10.1056/NEJMoa2114255
N Engl J Med 2021; 385:1393-1400
On July 30, 2021, the administration of a third (booster) dose of the BNT162b2 messenger RNA vaccine (Pfizer–BioNTech) was approved in Israel for persons who were 60 years of age or older and who had received a second dose of vaccine at least 5 months earlier. Data are needed regarding the effect of the booster dose on the rate of confirmed coronavirus 2019 disease (Covid-19) and the rate of severe illness.
Pan-Sarbecovirus Neutralizing Antibodies in BNT162b2-Immunized SARS-CoV-1 Survivors
Chee-Wah Tan, Ph.D., Wan-Ni Chia, Ph.D., Barnaby E. Young, M.R.C.P., Feng Zhu, Ph.D., Beng-Lee Lim, M.Sc., Wan-Rong Sia, B.S., Tun-Linn Thein, M.P.H., Mark I.-C. Chen, Ph.D., Yee-Sin Leo, F.R.C.P., David C. Lye, F.R.C.P., and Lin-Fa Wang, Ph.D.
doi : 10.1056/NEJMoa2108453
N Engl J Med 2021; 385:1401-1406
Autoimmune Hemolytic Anemias
Sigbjørn Berentsen, M.D., Ph.D., and Wilma Barcellini, M.D.
doi : 10.1056/NEJMra2033982
N Engl J Med 2021; 385:1407-1419
Pearly Penile Papules
Mar Ramirez-Lluch, M.D., and Angela Hernandez-Martin, M.D.
doi : 10.1056/NEJMicm2106984
N Engl J Med 2021; 385:1420
Intracardiac Cement Embolism
Gabe Weininger, B.S., and John A. Elefteriades, M.D., Ph.D.
doi : 10.1056/NEJMicm2032931
N Engl J Med 2021; 385:e49
Hard to Swallow
Michael J. Litt, M.D., Ph.D., Mary W. Montgomery, M.D., Kirstin M. Small, M.D., Amy L. Miller, M.D., Ph.D., and Joseph Loscalzo, M.D., Ph.D.
doi : 10.1056/NEJMcps2100980
N Engl J Med 2021; 385:1421-1427
Striving for Diversity in Research Studies
doi : 10.1056/NEJMe2114651
N Engl J Med 2021; 385:1429-1430
Covid-19 Vaccine Effectiveness and the Test-Negative Design
Natalie E. Dean, Ph.D., Joseph W. Hogan, Sc.D., and Mireille E. Schnitzer, Ph.D.
doi : 10.1056/NEJMe2113151
N Engl J Med 2021; 385:1431-1433
Drainage for Infected Pancreatic Necrosis — Is the Waiting the Hardest Part?
Todd H. Baron, M.D.
doi : 10.1056/NEJMe2110313
N Engl J Med 2021; 385:1433-1435
Audio Interview: Are Covid-19 Vaccine Boosters Necessary?
Eric J. Rubin, M.D., Ph.D., Lindsey R. Baden, M.D., and Stephen Morrissey, Ph.D.
doi : 10.1056/NEJMe2115835
N Engl J Med 2021; 385:e63
In Gratitude for mRNA Vaccines
Lynda M. Stuart, M.D., Ph.D.
doi : 10.1056/NEJMcibr2111445
N Engl J Med 2021; 385:1436-1438
Adjuvant Olaparib in BRCA-Mutated Breast Cancer
doi : 10.1056/NEJMc2112373
N Engl J Med 2021; 385:1439-1440
Sudden Cardiac Death and Myocardial Fibrosis in Persons with HIV
doi : 10.1056/NEJMc2112481
N Engl J Med 2021; 385:e50
