James C. Robinson, Ph.D., M.P.H.
doi : 10.1056/NEJMp2113679
N Engl J Med 2021; 385:2017-2019
Rachel E. Sachs, J.D., M.P.H., and Nicholas Bagley, J.D.
doi : 10.1056/NEJMp2115297
N Engl J Med 2021; 385:2019-2021
Jessica C. Stuart, M.D.
doi : 10.1056/NEJMp2112424
N Engl J Med 2021; 385:2021-2023
Mark D. Neuman, M.D., Rui Feng, Ph.D., Jeffrey L. Carson, M.D., Lakisha J. Gaskins, M.H.S., Derek Dillane, M.D., Daniel I. Sessler, M.D., Frederick Sieber, M.D., Jay Magaziner, Ph.D., M.S.Hyg., Edward R. Marcantonio, M.D., Samir Mehta, M.D., Diane Menio, M.S., Sabry Ayad, M.D., Trevor Stone, M.D., Steven Papp, M.D., Eric S. Schwenk, M.D., Nabil Elkassabany, M.D., Mitchell Marshall, M.D., J. Douglas Jaffe, D.O., Charles Luke, M.D., Balram Sharma, M.D., Syed Azim, M.D., Robert A. Hymes, M.D., Ki-Jinn Chin, M.D., Richard Sheppard, M.D., Barry Perlman, M.D., Ph.D., Joshua Sappenfield, M.D., Ellen Hauck, D.O., Ph.D., Mark A. Hoeft, M.D., Mark Giska, M.D., Yatish Ranganath, M.D., Tiffany Tedore, M.D., Stephen Choi, M.D., Jinlei Li, M.D., Ph.D., M. Kwesi Kwofie, M.D., Antoun Nader, M.D., Robert D. Sanders, M.D., Brian F.S. Allen, M.D., Kamen Vlassakov, M.D., Stephen Kates, M.D., Lee A. Fleisher, M.D., James Dattilo, B.S., Ann Tierney, M.S., Alisa J. Stephens-Shields, Ph.D., and Susan S. Ellenberg, Ph.D. for the REGAIN Investigators*
doi : 10.1056/NEJMoa2113514
N Engl J Med 2021; 385:2025-2035
The effects of spinal anesthesia as compared with general anesthesia on the ability to walk in older adults undergoing surgery for hip fracture have not been well studied.
Eric Jonasch, M.D., Frede Donskov, M.D., Ph.D., Othon Iliopoulos, M.D., W. Kimryn Rathmell, M.D., Ph.D., Vivek K. Narayan, M.D., Benjamin?L. Maughan, M.D., Stephane Oudard, M.D., Tobias Else, M.D., Jodi K. Maranchie, M.D., Sarah J. Welsh, M.D., Sanjay? Thamake, Ph.D., Eric K. Park, M.D., Rodolfo F. Perini, M.D., W. Marston Linehan, M.D., and Ramaprasad Srinivasan, M.D., Ph.D. for the MK-6482-004 Investigators*
doi : 10.1056/NEJMoa2103425
N Engl J Med 2021; 385:2036-2046
Patients with von Hippel–Lindau (VHL) disease have a high incidence of renal cell carcinoma owing to VHL gene inactivation and constitutive activation of the transcription factor hypoxia-inducible factor 2? (HIF-2?).
Junhao Yan, M.D., Ph.D., Yingying Qin, M.D., Ph.D., Han Zhao, M.D., Ph.D., Yun Sun, M.D., Ph.D., Fei Gong, M.D., Ph.D., Rong Li, M.D., Xiaoxi Sun, M.D., Ph.D., Xiufeng Ling, M.D., Ph.D., Hong Li, M.D., Cuifang Hao, M.D., Ph.D., Jichun Tan, Ph.D., Jing Yang, M.D., Ph.D., Yimin Zhu, M.D., Ph.D., Fenghua Liu, M.D., Dawei Chen, Ph.D., Daimin Wei, M.D., Ph.D., Juanjuan Lu, M.S., Tianxiang Ni, M.D., Ph.D., Wei Zhou, M.D., Ph.D., Keliang Wu, Ph.D., Yuan Gao, Ph.D., Yuhua Shi, M.D., Ph.D., Yao Lu, M.D., Ting Zhang, Ph.D., Wei Wu, M.D., Xiang Ma, M.D., Ph.D., Hailan Ma, Ph.D., Jing Fu, Ph.D., Junqiang Zhang, Ph.D., Qingxia Meng, M.D., Heping Zhang, Ph.D., Richard S. Legro, M.D., and Zi-Jiang Chen, M.D., Ph.D.
doi : 10.1056/NEJMoa2103613
N Engl J Med 2021; 385:2047-2058
Embryo selection with preimplantation genetic testing for aneuploidy (PGT-A) may improve pregnancy outcomes after initial embryo transfer. However, it remains uncertain whether PGT-A improves the cumulative live-birth rate as compared with conventional in vitro fertilization (IVF).
Junne Kamihara, M.D., Ph.D., Kayla V. Hamilton, M.S., C.G.C., Jessica A. Pollard, M.D., Catherine M. Clinton, M.S., Jill A. Madden, Ph.D., C.G.C., Jasmine Lin, M.S., Alma Imamovic, M.Sc., Catherine B. Wall, N.P., Ari J. Wassner, M.D., Brent R. Weil, M.D., M.P.H., Matthew M. Heeney, M.D., Sara O. Vargas, M.D., William G. Kaelin, Jr., M.D., Katherine A. Janeway, M.D., Rodolfo F. Perini, M.D., Naseem J. Zojwalla, M.D., Stephan D. Voss, M.D., Ph.D., and Steven G. DuBois, M.D.
doi : 10.1056/NEJMoa2110051
N Engl J Med 2021; 385:2059-2065
Paul S. Meltzer, M.D., Ph.D., and Lee J. Helman, M.D.
doi : 10.1056/NEJMra2103423
N Engl J Med 2021; 385:2066-2076
Tingting Wang, M.B., B.S., and Jia-Qi Chen, M.D., Ph.D.
doi : 10.1056/NEJMicm2108047
N Engl J Med 2021; 385:2077
Massimo Petruzzi, D.D.S., Ph.D., and Fedora della Vella, D.D.S.
doi : 10.1056/NEJMicm2108327
N Engl J Med 2021; 385:e77
Lisa G. Winston, M.D., Marisa L. Winkler, M.D., Ph.D., Arvin Kheterpal, M.D., and Julian A. Villalba, M.D.
doi : 10.1056/NEJMcpc2107357
N Engl J Med 2021; 385:2078-2086
James P. Rathmell, M.D., and Michael S. Avidan, M.B., B.Ch.
doi : 10.1056/NEJMe2116017
N Engl J Med 2021; 385:2088-2089
Manuela Schmidinger, M.D.
doi : 10.1056/NEJMe2114846
N Engl J Med 2021; 385:2090-2091
Eric J. Rubin, M.D., Ph.D., Lindsey R. Baden, M.D., and Stephen Morrissey, Ph.D.
doi : 10.1056/NEJMe2118514
N Engl J Med 2021; 385:e95
James O’Connell, M.B., B.Ch, B.A.O., David M. Nathan, M.D., Timothy O’Brien, M.D., Ph.D., and Derek T. O’Keeffe, M.D., Ph.D.
doi : 10.1056/NEJMclde2112076
N Engl J Med 2021; 385:2092-2095
Sebastiaan Mastenbroek, Ph.D., Guido de Wert, Ph.D., and Eli Y. Adashi, M.D.
doi : 10.1056/NEJMsb2101718
N Engl J Med 2021; 385:2096-2100
doi : 10.1056/NEJMc2114290
N Engl J Med 2021; 385:2101-2103
doi : 10.1056/NEJMc2112974
N Engl J Med 2021; 385:2103-2105
doi : 10.1056/NEJMc2115776
N Engl J Med 2021; 385:2105-2107
doi : 10.1056/NEJMc2114890
N Engl J Med 2021; 385:2107-2109
doi : 10.1056/NEJMc2115775
N Engl J Med 2021; 385:2109-2111
doi : 10.1056/NEJMc2115673
N Engl J Med 2021; 385:2111-2112
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