A. Khalil,K. Reed
doi : 10.1002/uog.23594
Volume 58, Issue 6 p. 799-803
L. Joyeux,M. A. Belfort,P. De Coppi,D. Basurto,I. Valenzuela,A. King,L. De Catte,A. A. Shamshirsaz,J. Deprest,S. G. Keswani
doi : 10.1002/uog.24759
Volume 58, Issue 6 p. 804-812
Gastroschisis (GS) is a congenital abdominal wall defect, in which the bowel eviscerates from the abdominal cavity. It is a non-lethal isolated anomaly and its pathogenesis is hypothesized to occur as a result of two hits: primary rupture of the ‘physiological’ umbilical hernia (congenital anomaly) followed by progressive damage of the eviscerated bowel (secondary injury). The second hit is thought to be caused by a combination of mesenteric ischemia from constriction in the abdominal wall defect and prolonged amniotic fluid exposure with resultant inflammatory damage, which eventually leads to bowel dysfunction and complications. GS can be classified as either simple or complex, with the latter being complicated by a combination of intestinal atresia, stenosis, perforation, volvulus and/or necrosis. Complex GS requires multiple neonatal surgeries and is associated with significantly greater postnatal morbidity and mortality than is simple GS. The intrauterine reduction of the eviscerated bowel before irreversible damage occurs and subsequent defect closure may diminish or potentially prevent the bowel damage and other fetal and neonatal complications associated with this condition. Serial prenatal amnioexchange has been studied in cases with GS as a potential intervention but never adopted because of its unproven benefit in terms of survival and bowel and lung function. We believe that recent advances in prenatal diagnosis and fetoscopic surgery justify reconsideration of the antenatal management of complex GS under the rubric of the criteria for fetal surgery established by the International Fetal Medicine and Surgery Society (IFMSS). Herein, we discuss how conditions for fetoscopic repair of complex GS might be favorable according to the IFMSS criteria, including an established natural history, an accurate prenatal diagnosis, absence of fully effective perinatal treatment due to prolonged need for neonatal intensive care, experimental evidence for fetoscopic repair and maternal and fetal safety of fetoscopy in expert fetal centers. Finally, we propose a research agenda that will help overcome barriers to progress and provide a pathway toward clinical implementation. © 2021 International Society of Ultrasound in Obstetrics and Gynecology.
V. Giorgione,F. D'antonio,A. Manji,K. Reed,A. Khalil
doi : 10.1002/uog.23585
Volume 58, Issue 6 p. 813-823
To report the perinatal outcome of monochorionic diamniotic (MCDA) twin pregnancies complicated by twin anemia–polycythemia sequence (TAPS), according to the type of TAPS (spontaneous or postlaser) and the management option adopted.
L. Sun,J. F. P. van Amerom,D. Marini,S. Portnoy,F.-T. Lee,B. S. Saini,J. M. Lim,J. Aguet,E. Jaeggi,J. C. Kingdom,C. K. Macgowan,S. P. Miller,G. Huang,M. Seed
doi : 10.1002/uog.23707
Volume 58, Issue 6 p. 824-836
To characterize, using magnetic resonance imaging (MRI), the distribution of blood flow and oxygen transport in human fetuses with subtypes of congenital heart disease (CHD) that present with neonatal cyanosis.
E. Seidl-Mlczoch,G. Kasprian,A. Ba-ssalamah,M. Stuempflen,E. Kitzmueller,D. A. Muin,D. Zimpfer,D. Prayer,I. Michel-behnke,B. Ulm
doi : 10.1002/uog.23705
Volume 58, Issue 6 p. 837-845
Heterotaxy or isomerism of the atrial appendages is a congenital disorder with variable presentation, associated with both cardiac and non-cardiac anomalies, which may have a serious impact on fetal outcome. The aim of this exploratory study was to assess the value of fetal magnetic resonance imaging (MRI), as a complementary tool to ultrasound, for describing the morphological spectrum encountered in heterotaxy.
C. Vedel,L. Rode,H. Bundgaard,K. Iversen,F. S. Jørgensen,O. B. Petersen,A.-S. Sillesen,K. Sundberg,N. Vejlstrup,H. Zingenberg,A. Tabor,C. K. Ekelund
doi : 10.1002/uog.23670
Volume 58, Issue 6 p. 846-852
To investigate prenatal changes in cardiac biometric and flow parameters in fetuses with bicuspid aortic valve (BAV) diagnosed neonatally compared with controls with normal cardiac anatomy.
L. Herling,J. Johnson,K. Ferm-Widlund,A. Zamprakou,M. Westgren,G. Acharya
doi : 10.1002/uog.23703
Volume 58, Issue 6 p. 853-863
The primary aim of this study was to evaluate the feasibility of automated measurement of fetal atrioventricular (AV) plane displacement (AVPD) over several cardiac cycles using myocardial velocity traces obtained by color tissue Doppler imaging (cTDI). The secondary objectives were to establish reference ranges for AVPD during the second half of normal pregnancy, to assess fetal AVPD in prolonged pregnancy in relation to adverse perinatal outcome and to evaluate AVPD in fetuses with a suspicion of intrauterine growth restriction (IUGR).
K. Krajden Haratz,P. Oliveira Szejnfeld,M. Govindaswamy,Z. Leibovitz,L. Gindes,M. Severino,A. Rossi,D. Paladini,R. Garcia Rodriguez,L. Ben-Sira,T. Borkowski Tillman,R. Gupta,G. Lotem,N. Raz,T. E. N. K. Hamamoto,D. Kidron,A. Arad,R. Birnbaum,M. Brussilov,L. Pomar,Y. Vial,R. J. Leventer,G. McGillivray,M. Fink,W. Krzeszowski,A. Fernandes Moron,D. Lev,M. Tamarkin,J. Shalev,J. Har Toov,T. Lerman-Sagie,G. Malinger
doi : 10.1002/uog.23660
Volume 58, Issue 6 p. 864-874
To describe the prenatal neuroimaging spectrum of rhombencephalosynapsis (RES) and criteria for its classification according to the severity of vermian anomaly.
F. Fontanella,H. Groen,L. K. Duin,S. Suresh,C. M. Bilardo
doi : 10.1002/uog.23647
Volume 58, Issue 6 p. 875-881
To construct reference values for fetal urinary bladder distension in pregnancy and use Z-scores as a diagnostic tool to differentiate posterior urethral valves (PUV) from urethral atresia (UA).
R. L. Deter,W. Lee,P. Dicker,E. C. Tully,F. Cody,F. D. Malone,K. M. Flood
doi : 10.1002/uog.23688
Volume 58, Issue 6 p. 882-891
We have shown previously that third-trimester growth in small fetuses (estimated fetal weight (EFW) <?10th percentile) with birth weight (BW) <?10th percentile is heterogeneous using individualized growth assessment (IGA). We aimed to test our hypothesis that individual growth patterns in small fetuses with BW >?10th percentile are also variable but in different ways.
J. G. Martins,T. Kawakita,M. Gurganus,D. Baraki,P. Jain,A. T. Papageorghiou,A. Z. Abuhamad
doi : 10.1002/uog.23646
Volume 58, Issue 6 p. 892-899
To determine the interobserver reproducibility of fetal ultrasound biometric and amniotic-fluid measurements in the third trimester of pregnancy, according to maternal body mass index (BMI) category.
R. Sevilla-Montoya,A. Hidalgo-Bravo,G. Estrada-Gutiérrez,O. Villavicencio-Carrisoza,M. Leon-Juarez,I. Villegas-Mota,S. Espino-y-Sosa,I. E. Monroy-Muñoz,R. J. Martinez-Portilla,L. C. Poon,J. A. Cardona-Pérez,A. C. Helguera-Repetto,Collaborators
doi : 10.1002/uog.24787
Volume 58, Issue 6 p. 900-908
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vertical transmission has been investigated extensively. Recently, the World Health Organization (WHO) published strict criteria to classify the timing of mother-to-child transmission of SARS-CoV-2 into different categories. The aim of this study was to investigate the possibility of vertical transmission in asymptomatic SARS-CoV-2-positive women.
C. Kyriacou,N. Cooper,E. Robinson,N. Parker,J. Barcroft,S. Kundu,P. Letchworth,S. Sur,D. Gould,C. Stalder,T. Bourne
doi : 10.1002/uog.24793
Volume 58, Issue 6 p. 909-915
To describe and compare the characteristics of ectopic pregnancies (EPs) in the year prior to vs during the coronavirus disease 2019 (COVID-19) pandemic.
F. Moro,V. Bertoldo,G. Avesani,M. C. Moruzzi,F. Mascilini,G. Bolomini,G. Caliolo,R. Esposito,R. Moroni,G. F. Zannoni,A. Fagotti,R. Manfredi,G. Scambia,A. C. Testa
doi : 10.1002/uog.23650
Volume 58, Issue 6 p. 916-925
Fusion imaging is an emerging technique that combines real-time ultrasound examination with images acquired previously using other modalities, such as computed tomography (CT), magnetic resonance imaging and positron emission tomography. The primary aim of this study was to evaluate the feasibility of fusion imaging in patients with suspicion of ovarian or peritoneal cancer. Secondary aims were: to compare the agreement of findings on fusion imaging, CT alone and ultrasound imaging alone with laparoscopic findings, in the assessment of extent of intra-abdominal disease; and to evaluate the time required for the fusion imaging technique.
C. Ros,C. de Guirior,E. Mension,M. Rius,M. Valdés-Bango,M. Tortajada,I. Matas,M. Á. Martínez-Zamora,M. Gracia,F. Carmona
doi : 10.1002/uog.23696
Volume 58, Issue 6 p. 926-932
To evaluate the accuracy of transvaginal ultrasound (TVS) in diagnosing deep endometriosis (DE) involving the uterosacral ligaments (USLs), torus uterinus (TU) or posterior vaginal fornix (PVF) in women with suspected endometriosis scheduled for laparoscopic surgery.
M. K. Aas-Eng,M. Lieng,B. Dauser,L. M. Diep,M. Leonardi,G. Condous,G. Hudelist
doi : 10.1002/uog.23728
Volume 58, Issue 6 p. 933-939
To investigate the agreement of measurements of the three diameters of rectosigmoid deep endometriosis (DE) lesions between presurgical evaluation using transvaginal sonography (TVS) and postsurgical specimen measurement (PSM).
K. Gill,N. Arbic,M. Seed,O. Honjo,G. Ryan,E. Jaeggi
doi : 10.1002/uog.24758
Volume 58, Issue 6 p. 940-942
We report on a fetal case of Ebstein's anomaly with severe tricuspid regurgitation, functional pulmonary atresia and progressive circular shunting (CS) across a widely patent ductus arteriosus (DA) and regurgitant pulmonary valve, contributing to significant systemic hypoperfusion. To mitigate the extent of CS and allow the pregnancy to continue, maternal non-steroidal anti-inflammatory drug (NSAID) therapy with indomethacin was started at 33?+?5?weeks to induce DA constriction. Rather than achieving the desired narrowing of the DA, the treatment led to its complete closure and only minimal antegrade flow across the pulmonary valve. While closure of the DA resulted in the anticipated improvement in fetal hemodynamics, at birth, the child was at risk of severe hypoxemia and its consequences due to the lack of adequate pulmonary perfusion. Reduction and eventual discontinuation of the NSAID treatment did not result in DA reopening. Our experience illustrates the risk of unintended irreversible DA closure when NSAIDs are used to treat CS. © 2021 International Society of Ultrasound in Obstetrics and Gynecology.
R. Romero,A. Conde-Agudelo,L. Rode,M. L. Brizot,E. Cetingoz,V. Serra,E. Da Fonseca,A. Tabor,A. Perales,S. S. Hassan,K. H. Nicolaides
doi : 10.1002/uog.24765
Volume 58, Issue 6 p. 943-945
I. Musilova,P. Elias,J. Stranik,A. Matejkova,M. Kacerovsky
doi : 10.1002/uog.23598
Volume 58, Issue 6 p. 945-946
R. K. Gajbhiye,A. Tilve,S. Kesarwani,S. Srivastava,S. J. Kore,K. Patil,S. D. Mahale,N. N. Mahajan
doi : 10.1002/uog.24784
Volume 58, Issue 6 p. 946-949
J. Luna-García,M. Martínez-Rodríguez,L. López-Saiz,R. Villalobos-Gómez,R. Cruz-Martínez
doi : 10.1002/uog.23710
Volume 58, Issue 6 p. 949-950
R. S. Abu-Rustum,O. Moumne,R. Egerman,H. Vyas
doi : 10.1002/uog.23704
Volume 58, Issue 6 p. 950-953
R. Lachmann,A. Brückmann
doi : 10.1002/uog.23124
Volume 58, Issue 6 p. 954-955
We thank Dr Lakshmy and colleagues1 for their thorough evaluation of the early diagnosis of cleft lip and palate using the midsagittal view. However, we would like to draw readers' attention to their apparent misinterpretation of measurement of the palatomaxillary diameter (PMD), which, we feel, might impact the conclusions of their paper.
R. Mungmunpuntipantip,V. Wiwanitkit
doi : 10.1002/uog.24811
Volume 58, Issue 6 p. 958-958
We would like to share our thoughts on the recently published study of Bookstein Peretz et?al., in which it was concluded that the BNT162b2 mRNA coronavirus disease 2019 (COVID-19) vaccine is effective in generating a humoral immune response in pregnant women, although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunoglobulin G levels were lower than those observed in non-pregnant vaccinated women1. The safety of the vaccine has been confirmed, and we agree that COVID-19 vaccination is, without doubt, useful for pregnant women. However, the observed SARS-CoV-2 antibody levels should be interpreted carefully. During pregnancy, the plasma volume is expanded, which affects many clinical parameters, including antibody levels2. In laboratory medicine, adjustment for the dilutional effect of the plasma is required for interpretation of laboratory results, and specific reference values for different timepoints in pregnancy should be set, as the degree of plasma volume expansion varies during pregnancy3.
A. Macedo Jr,M. Leal da Cruz
doi : 10.1002/uog.24801
Volume 58, Issue 6 p. 958-959
We congratulate the authors of the recently published paper on the effect of percutaneous fetoscopic spina bifida repair on postnatal outcome1 for their collaborative work which represents a major advance in prenatal treatment of myelomeningocele. We would, however, like to express our concern regarding the lack of care in handling urologic information in their paper, which is focused on the obstetric point of view but includes the outcome ‘need for bladder catheterization’ in the title and summary. Every conclusion in any manuscript should be grounded on good methodology, and it should be borne in mind that imprecise information can lead to misunderstanding and false interpretation. We would like to raise some points for the authors to consider:
D. A. Lapa,the coauthors,J. V. de Souza Leão
doi : 10.1002/uog.24802
Volume 58, Issue 6 p. 959-960
B. Karmegaraj
doi : 10.1002/uog.23657
Volume 58, Issue 6 p. 961-963
doi : 10.1002/uog.24808
Volume 58, Issue 6 p. 964-967
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