Choi, Jeongmin MD1
doi : 10.14309/crj.0000000000000754
February 2022 - Volume 9 - Issue 2 - p e00754
Eskarous, Hany MD1; Patel, Dhruv MD2; Geme, Berhanu MD2; Krishnamurthy, Mahesh MD1
doi : 10.14309/crj.0000000000000750
February 2022 - Volume 9 - Issue 2 - p e00750
Maddileti, Varunkumar MCh1; Mammen, Abraham MCh1; Kuruvilla, Shalini MD2
doi : 10.14309/crj.0000000000000749
February 2022 - Volume 9 - Issue 2 - p e00749
Kaposiform hemangioendothelioma is a borderline vascular tumor usually seen in infants and children as cutaneous lesions classically associated with the Kasabach-Merritt phenomenon. Intestinal involvement is uncommon and can cause acute presentations, such as obstruction or gastrointestinal bleeding. A 5-day-old neonate presented with bilious vomiting for 2 days. The tumor was in the jejunum. Histopathological examination with immunohistochemistry of the resected jejunum showed CD34 positive endothelial lined vascular spaces infiltrating from submucosa to serosa, which is classical of kaposiform hemangioendothelioma. There was no deranged coagulation profile. This case forms an interesting cause for neonatal intestinal obstruction.
Verhoeff, Kevin MD1; Bacani, Julinor MD2; Fung, Christopher MD3; Canterbury, Laura A. MD2
doi : 10.14309/crj.0000000000000746
February 2022 - Volume 9 - Issue 2 - p e00746
Cholangioblastic variant of cholangiocarcinoma is rare and may be encountered in young adults with a liver mass. On biopsy, the pathologic features may mimic neuroendocrine or other tumors. Increased awareness of this unusual variant and the typical strong expression of the immunohistochemical marker inhibin may help prevent diagnostic errors. Because only a few cases have been reported, we also discuss treatment options in a 26-year-old man.
Dutra, Barbara MD, RD1; Welborn, Macartney MD1; Thosani, Nirav C. MD, MHA1; Badillo, Ricardo MD1; DaVee, Tomas MD, MSCI1; Bhakta, Dimpal MD1
doi : 10.14309/crj.0000000000000743
February 2022 - Volume 9 - Issue 2 - p e00743
Bile leaks may be seen after blunt and penetrating trauma, as well as iatrogenic injury from surgical procedures. There are many articles on endoscopic treatment options for the management of biliary leaks, including sphincterotomy, endoscopic stent, or nasobiliary drain placement. Data, however, are scarce regarding the management of persistent biliary leaks after the initial intervention. We present a case of endoscopic coil embolization to treat a refractory bile leak after initial endoscopic sphincterotomy and stent placement in a patient with a grade IV liver laceration due to a gunshot wound.
Nguyen, Anita H. MD1; Sagvand, Babak Torabi MD2; Hwang, Daniel G. MD2; Legesse, Teklu MD3; Cross, Raymond K. MD, MS, FACG, AGAF2
doi : 10.14309/crj.0000000000000747
February 2022 - Volume 9 - Issue 2 - p e00747
Immune checkpoint inhibitors such as nivolumab increase the T-cell destruction of malignancies but can also trigger a broad variety of immune-related adverse events (irAEs). Colitis as an irAE is well-documented, but upper gastrointestinal tract involvement is primarily unrecognized. We present a patient who developed gastritis as an irAE after multiple cycles of nivolumab and initially responded well to steroid therapy but then developed superimposed cytomegalovirus infection. The similarity between both presentations highlights the importance of having a broad differential diagnosis in patients with gastrointestinal complaints treated with immune checkpoint inhibitors and the need for further studies to better characterize gastritis as an irAE.
Benanzer, Tessa M. MD1; Kamboj, Amrit K. MD1,2; Sweetser, Seth MD1,2
doi : 10.14309/crj.0000000000000686
February 2022 - Volume 9 - Issue 2 - p e00686
Bloom syndrome is an inherited disorder involving a characteristic phenotype of short stature, photosensitive rash, immunodeficiency, and an early predisposition to various cancers, including lymphoma and colorectal neoplasms. We present a patient with Bloom syndrome found to have a colonic mass secondary to diffuse large B-cell lymphoma highlighting the importance of cancer screening and surveillance in these patients.
McDonald, Nicholas M. MD1
doi : 10.14309/crj.0000000000000745
February 2022 - Volume 9 - Issue 2 - p e00745
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