AO Spine RECODE-DCM: Why Prioritize Research in Degenerative Cervical Myelopathy?

Benjamin M. Davies, MBChB(Hons), BSc, MPhil, Brian K. Kwon, MD, PhD, Michael G. Fehlings, MD, PhD, Mark R. N. Kotter, MD, MPhil, PhD

doi : 10.1177/21925682211035379

First Published February 17, 2022; pp. 5S–7S

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Gathering Global Perspectives to Establish the Research Priorities and Minimum Data Sets for Degenerative Cervical Myelopathy: Sampling Strategy of the First Round Consensus Surveys of AO Spine RECODE-DCM

Oliver D. Mowforth, MA MB Chir MRCS, Danyal Z Khan, MB, BCh, MRCS, AFHEA, Mei Yin Wong, BA, MB, BChir, George A. E. Pickering, MBChB (Hons), BMedSci, Lydia Dean, Joe Magee, Laura Mullarkey, MA MB BChir, Yuri Hirayama, Msci MA MB BChir (Cantab), Martina Rihova, MBBChir, Max Butler, BA BSc (Hons), Max Stewart, BA MB BChir, Beth Goulson, BA MB BChir, Shahzaib Ahmed, BAP, Kai Fricke, MSc MB BChir, Vladimir Popa-Nimigean, BA MB BChir, Zack Millar, BA MB BChir, Ashwin Venkatesh, BA, Alice Willison, Keerthi Senthil, MA MB BChir, MB, Bchir, Olesja Hazenbiller, MSc, PMP, Ellen Sarewitz, Iwan Sadler, Toto Gronlund, BSc, MSc, Lindsay Tetreault, MD, PhD, James S. Harrop, MD, MSHQS, FACS, Bizhan Aarabi, MD, Vafa Rahimi-Movaghar, MD, Shekar N Kurpad, MD, PhD, James D. Guest, MD, PhD, FACS, Jefferson R. Wilson, MD, PhD FRCSC, Brian K. Kwon, MD, PhD, FRCSC, Michael G. Fehlings, MD, PhD, FRCSC, FACS, Angus G.K. McNair, MB ChB PhD FRCSFHEA, Benjamin M. Davies, MRCS, BSc, MPhil, Mark R.N. Kotter, MD, M.Phil, PhD, On behalf of the AO Spine RECODE-DCM Steering Committee and AO Spine RECODE-DCM Consortium

doi : 10.1177/21925682211047546

First Published December 8, 2021; pp. 8S–18S

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James Lind Alliance Priority Setting Partnership for Degenerative Cervical Myelopathy [AO Spine RECODE-DCM]: An Overview of the Methodology Used to Process and Short-List Research Uncertainties

Lindsay Tetreault, MD, PhD, Oliver Mowforth, MRCS, Danyal Z. Khan, MB, BCh, MRCS, AFHEA, Toto Gronlund, BSc, MSc, Philip Garwood, MD, Olesja Hazenbiller, MSC, PMP, James S. Harrop, MD, MSHQS, FACS, Bizhan Aarabi, MD, Vafa Rahimi-Movaghar, MD, Shekar N. Kurpad, MD, PhD, James D. Guest, MD, PhD, FACS, Jefferson R. Wilson, MD, PhD FRCSC, Brian K. Kwon, MD PhD FRCSC, Michael G. Fehlings, MD, PhD, FRCSC, FACS, Benjamin M. Davies, MRCS, BSc, MPhil, Mark R. N. Kotter, MD, MPhil, PhD, On behalf of the AO Spine RECODE-DCM Steering Committee and AO Spine RECODE-DCM Consortium

doi : 10.1177/21925682211062501

First Published February 17, 2022; pp. 19S–27S

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Improving Awareness Could Transform Outcomes in Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 1]

Benjamin M. Davies, MRCS, BSc, MPhil, Oliver Mowforth, MRCS, Helen Wood, LLB, MA, Zahabiya Karimi, BA, Iwan Sadler, Lindsay Tetreault, MD, PhD, Jamie Milligan, MD, Jamie R. F. Wilson, BM, BCh, MSc, FRCS, Sukhvinder Kalsi-Ryan, BScPT, MSc, PhD, Julio C. Furlan, MD, LLB, MBA, PhD, MSc, FRCPC, Yoshiharu Kawaguchi, MD, PhD, Manabu Ito, MD, PhD, Carl Moritz Zipser, MD, FEBN, Timothy F Boerger, PhD, Alexander R. Vaccaro, MD, PhD, MBA, Rory K. J. Murphy, MD, Mike Hutton, FRSC (Tr&Ortho), Ricardo Rodrigues-Pinto, MD, PhD, FEBOT, Paul A. Koljonen, MBBS(HK), FRCSEd(Ortho), FHKCOS, FHKAM(Orthopaedic Surgery), James S. Harrop, MD, MSHQS, FACS, Bizhan Aarabi, MD, Vafa Rahimi-Movaghar, MD, Shekar N Kurpad, MD, PhD, James D. Guest, MD, PhD, FACS, Jefferson R. Wilson, MD, PhD, FRCSC, Brian K. Kwon, MD, PhD, FRCSC, Mark R. N. Kotter, MD, MPhil, PhD, Michael G. Fehlings, MD, PhD, FRCSC, FACS

doi : 10.1177/21925682211050927

First Published February 17, 2022; pp. 28S–38S

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Degenerative Cervical Myelopathy: Development and Natural History [AO Spine RECODE-DCM Research Priority Number 2]

Aria Nouri, MD, MSc, Enrico Tessitore, MD, Granit Molliqaj, MD, Torstein Meling, MD, PhD, Karl Schaller, MD, Hiroaki Nakashima, MD, PhD, Yasutsugu Yukawa, MD, PhD, Josef Bednarik, MD, PhD, Allan R. Martin, MD, PhD, Peter Vajkoczy, MD, Joseph S. Cheng, MD, MS, Brian K. Kwon, MD, PhD, Shekar N. Kurpad, MD, PhD, Michael G. Fehlings, MD, PhD, James S. Harrop, MD, MSHQS, Bizhan Aarabi, MD, Vafa Rahimi-Movaghar, MD, James D. Guest, MD, PhD, Benjamin M. Davies, MRCS, BSc, MPhil, Mark R. N. Kotter, MD, MPhil, PhD, Jefferson R. Wilson, MD, PhD

doi : 10.1177/21925682211036071

First Published February 17, 2022; pp. 39S–54S

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Establishing Diagnostic Criteria for Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 3]

Bryn Hilton, BA, MB BChir, Emma L. Gardner, BA, MB BChir, Zhilin Jiang, BA, MBBS, Lindsay Tetreault, MD, PhD, Jamie R. F. Wilson, BM, BCh, MSc, Carl Moritz Zipser, MD, FEBN, K. Daniel Riew, MD, James D. Guest, MD, PhD, James S. Harrop, MD, MSHQS, Michael G. Fehlings, MD, PhD, Ricardo Rodrigues-Pinto, MD, PhD, FEBOT, Vafa Rahimi-Movaghar, MD, Bizhan Aarabi, MD, Paul A. Koljonen, MBBS(HK), FHKCOS FHKAM(Orthopaedic Surgery), Mark R. N. Kotter, MD, MPhil, PhD, Benjamin M. Davies, MRCS, BSc, MPhi, Brian K. Kwon, MD, PhD

doi : 10.1177/21925682211030871

First Published February 17, 2022; pp. 55S–63S

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Improving Assessment of Disease Severity and Strategies for Monitoring Progression in Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 4]

Lindsay Tetreault, MD, PhD, Philip Garwood, MD, Aref-Ali Gharooni, MBChB, MSc (Dist.), Alvaro Yanez Touzet, MBChB, BS, Laura Nanna-Lohkamp, MD, MSc, Allan Martin, MD, PhD, Jefferson Wilson, MD, PhD, FRCSC, James S. Harrop, MD, MSHQS, FACS, James Guest, MD, PhD, FACS, Brian K. Kwon, MD, PhD, FRCSC, James Milligan, MD, Alberto Martinez Arizala, MD, K. Daniel Riew, MD, Michael G. Fehlings, MD, PhD, FRCSC, FACS, Mark R. N. Kotter, MD, M.Phil, PhD, Sukhvinder Kalsi-Ryan, BScPT, MSc, PhD, Benjamin M. Davies, MRCS BSc, MPhil

doi : 10.1177/21925682211063854

First Published December 31, 2021; pp. 64S–77S

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A New Framework for Investigating the Biological Basis of Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 5]: Mechanical Stress, Vulnerability and Time

Benjamin M. Davies, MRCS, BSc, MPhil, Oliver Mowforth, MRCS, Aref-Ali Gharooni, MBChB, MSc (Dist), Lindsay Tetreault, MD, PhD, Aria Nouri, MD, MSc, Rana S. Dhillon, MD, Josef Bednarik, MD, PhD, Allan R. Martin, MD, PhD, Adam Young, Hitoshi Takahashi, Timothy F. Boerger, PhD, Virginia FJ Newcombe, MD, PhD, Carl Moritz Zipser, MD, FEBN, Patrick Freund, MD, PhD, Paul Aarne Koljonen, MBBS(HK), FRCSEd(Ortho), FHKCOS, FHKAM(Orthopaedic Surgery), Ricardo Rodrigues-Pinto, MD PhD, FEBOT, Vafa Rahimi-Movaghar, MD, Jefferson R. Wilson, MD, PhD, FRCSC, Shekar N Kurpad, MD, PhD, Michael G. Fehlings, MD, PhD, FRCSC, FACS, Brian K. Kwon, MD, PhD, FRCSC, James S. Harrop, MD, MSHQS, FACS, James D. Guest, MD, PhD FACS, Armin Curt, MD, FRCPC, Mark R. N. Kotter, MD MPhil, PhD

doi : 10.1177/21925682211057546

First Published February 17, 2022; pp. 78S–96S

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Developing Peri-Operative Rehabilitation in Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 6]: An Unexplored Opportunity?

Timothy F. Boerger, PhD, ATC, Allison S. Hyngstrom, PT, PhD, Julio C. Furlan, MD, LLB, MBA, PhD, MSc, FRCPC, Sukhvinder Kalsi-Ryan, BScPT, MSc PhD, Armin Curt, MD, FRCPC, Brian K. Kwon, MD, PhD, FRCSC, Shekar N. Kurpad, MD, PhD, Michael G. Fehlings, MD, PhD, FRCSC, FACS, James S. Harrop, MD, MSHQS, FACS, Bizhan Aarabi, MD, Vafa Rahimi-Movaghar, MD, James D. Guest, MD, PhD, FACS, Jefferson R. Wilson, MD, PhD, FRCSC, Benjamin M. Davies, MRCS, BSc, MPhil, Mark R. N. Kotter, MD, MPhil, PhD, Paul A. Koljonen, MBBS(HK), FRCSEd(Ortho), FHKCOS, FHKAM(Orthopaedic Surgery)

doi : 10.1177/21925682211050925

First Published February 17, 2022; pp. 97S–108S

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Developing Novel Therapies for Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 7]: Opportunities From Restorative Neurobiology

Aref-Ali Gharooni, MBChB, MSc (Dist), Brian K. Kwon, MD, PhD, FRCSC, Michael G. Fehlings, MD, PhD, FRCSC, FACS, Timothy F. Boerger, PhD, Ricardo Rodrigues-Pinto, MD, PhD, FEBOT, Paul Aarne Koljonen, MBBS(HK), FRCSEd(Ortho), FHKCOS, FHKAM(Orthopaedic Surgery), Shekar N. Kurpad, MD, PhD, James S. Harrop, MD, MSHQS, FACS, Bizhan Aarabi, MD, Vafa Rahimi-Movaghar, MD, Jefferson R. Wilson, MD, PhD, FRCSC, Benjamin M. Davies, MRCS, BSc, MPhil, Mark R. N. Kotter, MD, MPhil, PhD, James D. Guest, MD, PhD, FACS

doi : 10.1177/21925682211052920

First Published February 17, 2022; pp. 109S–121S

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Establishing the Socio-Economic Impact of Degenerative Cervical Myelopathy Is Fundamental to Improving Outcomes [AO Spine RECODE-DCM Research Priority Number 8]

Bryn Hilton, BA, MB BChir, Emma L. Gardner, BA, MB BChir, Zhilin Jiang, BA, MBBS, Lindsay Tetreault, MD, PhD, Jamie R. F. Wilson, BM, BCh, MSc, Carl Moritz Zipser, MD, FEBN, K. Daniel Riew, MD, James D. Guest, MD, PhD, James S. Harrop, MD, MSHQS, Michael G. Fehlings, MD, PhD, Ricardo Rodrigues-Pinto, MD, PhD, FEBOT, Vafa Rahimi-Movaghar, MD, Bizhan Aarabi, MD, Paul A. Koljonen, MBBS(HK), FHKCOS FHKAM(Orthopaedic Surgery), Mark R. N. Kotter, MD, MPhil, PhD, Benjamin M. Davies, MRCS, BSc, MPhi, Brian K. Kwon, MD, PhD

doi : 10.1177/21925682211039835

First Published February 17, 2022; pp. 122S–129S

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Imaging and Electrophysiology for Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 9]

doi : 10.1177/21925682211057484

First Published November 19, 2021; pp. 130S–146S

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Optimizing the Application of Surgery for Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 10]

doi : 10.1177/21925682211062494

First Published February 17, 2022; pp. 147S–158S

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The AO Spine RECODE-DCM International Collaborative—Establishing the Foundations for Accelerated and Patient-Centered Innovation

Danyal Z. Khan, MRCS, Olesja Hazenbiller, MSc, Toto Gronlund, MSc, Iwan Sadler, Ellen B. Sarewitz, MA, Oliver Mowforth, MRCS, Mark R. N. Kotter, FRCS, PhD, Benjamin M. Davies, MRCS, BSc, MPhilOn behalf of the AO Spine RECODE-DCM Steering Committee, AO Spine RECODE-DCM Global Partners and AO Spine RECODE-DCM Community

doi : 10.1177/21925682211035381

First Published February 17, 2022; pp. 159S–171S

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