دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه
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A Panel of Biomarkers Associates With Increased Risk for Cardiovascular Events in Women With Systemic Lupus Erythematosus
Brian J. Skaggs Jennifer Grossman Lori Sahakian Lucas Perry John FitzGerald Christina Charles?Schoeman Alan Gorn Mihaela Taylor John Moriarty Nagesh Ragavendra Michael Weisman Daniel J. Wallace Bevra H. Hahn Maureen McMahon … See fewer authors
doi : 10.1002/acr2.11223
ACR Open RheumatologyVolume 3, Issue 4 p. 209-220
The increase in cardiovascular events (CVEs) in systemic lupus erythematosus (SLE) is not fully explained by traditional risk factors. We previously identified four biomarkers (proinflammatory high?density lipoprotein, leptin, soluble TNF?like weak inducer of apoptosis (sTWEAK), and homocysteine) that we combined with age and diabetes to create the predictors of risk for elevated flares, damage progression, and increased cardiovascular diseasein patients with SLE (PREDICTS) risk profile. PREDICTS more accurately identified patients with SLE at risk for progression of subclinical atherosclerosis than any individual variable. We examined whether PREDICTS can also identify patients with SLE at risk for future CVEs.
The Impact of Asthma and Chronic Obstructive Pulmonary Disease (COPD) on Patient?Reported Outcomes in Systemic Lupus Erythematosus (SLE)
Patricia Katz Sofia Pedro Laura Trupin Edward Yelin Kaleb Michaud
doi : 10.1002/acr2.11212
ACR Open RheumatologyVolume 3, Issue 4 p. 221-230
Risk of asthma and chronic obstructive pulmonary disease (COPD) may be elevated in systemic lupus erythematosus (SLE), but little research has studied the impact of these conditions on SLE outcomes. We examined prevalence, incidence, and impact of self?reported asthma and COPD in two US?based SLE cohorts (FORWARD and Lupus Outcomes Study [LOS]).
Perspectives of Glucocorticoid Use in Patients with Rheumatoid Arthritis
Gabriella Venter Joanna Tieu Rachel Black Susan Lester Nieves Leonardo Samuel L. Whittle Elizabeth Hoon Claire Barrett Debra Rowett Rachelle Buchbinder Catherine L. Hill
doi : 10.1002/acr2.11234
ACR Open RheumatologyVolume 3, Issue 4 p. 231-238
Prednisolone is an effective oral glucocorticoid for managing symptoms of rheumatoid arthritis (RA) but has predictable and common adverse effects. We explored patient perspectives of prednisolone use in RA.
Validation of Self?Reported Rheumatoid Arthritis Using Medicare Claims: A Nationally Representative Longitudinal Study of Older Adults
Michael J. Booth Daniel Clauw Mary R. Janevic Lindsay C. Kobayashi John D. Piette
doi : 10.1002/acr2.11229
ACR Open RheumatologyVolume 3, Issue 4 p. 239-249
To determine the validity of self?reported physician diagnosis of rheumatoid arthritis (RA) using multiple gold?standard measures based on Medicare claims in a nationally representative sample of older adults and to verify whether additional questions about taking medication and having seen a physician in the past two years for arthritis can improve the positive predictive value (PPV) and other measures of the validity of self?reported RA.
Illness Uncertainty in Parents of Children with Juvenile Idiopathic Arthritis
Caroline Pearce Stanton Newman Kathleen Mulligan
doi : 10.1002/acr2.11238
ACR Open RheumatologyVolume 3, Issue 4 p. 250-259
To gain a better understanding of uncertainty regarding the illness experienced by parents of children with juvenile idiopathic arthritis (JIA).
Transition Readiness in Adolescents With Juvenile Idiopathic Arthritis and Childhood?Onset Systemic Lupus Erythematosus
Jeanine McColl Teresa Semalulu Karen A. Beattie Arzoo Alam Steffy Thomas Julie Herrington Jan Willem Gorter Tania Cellucci Stephanie Garner Liane Heale Mark Matsos Michelle Batthish
doi : 10.1002/acr2.11237
ACR Open RheumatologyVolume 3, Issue 4 p. 260-265
The transition from pediatric to adult rheumatology care represents a particularly vulnerable time for patients with juvenile idiopathic arthritis (JIA) and childhood?onset systemic lupus erythematosus (cSLE). Improving self?management skills is important in optimizing health care transition. The study’s objectives were to 1) examine variability in transition readiness of adolescents and young adults within and between different ages, sexes, and disease types; 2) determine the association between age and transition readiness; and 3) identify specific challenges to transition readiness for adolescents.
Clinical Images: A not so common overlap presentation in systemic lupus erythematosus
Ann M. Chodara Shivani Garg
doi : 10.1002/acr2.11248
ACR Open RheumatologyVolume 3, Issue 4 p. 266-266
Beta?2?Glycoprotein?I Deficiency Could Precipitate an Antiphospholipid Syndrome?like Prothrombotic Situation in Patients With Coronavirus Disease 2019
Manuel Serrano Gerard Espinosa Antonio Lalueza Luz Yadira Bravo?Gallego Raquel Diaz?Sim?n Sara Garcinu?o Javier Gil?Etayo Jorge Moises Laura Naranjo Sergio Prieto?Gonz?lez … See all authors
doi : 10.1002/acr2.11245
ACR Open RheumatologyVolume 3, Issue 4 p. 267-276
Patients with coronavirus disease 2019 (COVID?19) present coagulation abnormalities and thromboembolic events that resemble antiphospholipid syndrome (APS). This work has aimed to study the prevalence of APS?related antigens, antibodies, and immune complexes in patients with COVID?19 and their association with clinical events.
Decreased Levels of STAT1 and Interferon??–Induced STAT1 Phosphorylation in Rheumatoid Arthritis CD4 and CD8 T Cells
Vishal Sharma Brandon J. Pope Nathan V. Santiago Molly T. Boland Dongmei Sun Richard J. Reynolds Alexander J. Szalai S. Louis Bridges Jr Chander Raman
doi : 10.1002/acr2.11244
ACR Open RheumatologyVolume 3, Issue 4 p. 277-283
We investigated whether a previously reported association of IFNGR expression with rheumatoid arthritis (RA) and its radiographic severity reflects differences in proximal interferon?? (IFN??) signaling in T cells from patients with RA compared with healthy controls (HC).
