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سفارش

Smarter adaptive platform clinical trials in neurology

Masud Husain

doi : 10.1093/brain/awac005

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Jean Talairach: the man behind the cerebral stereotactic space

Marc Zanello, Alexandre Roux, Philibert Duriez, Anne-Sophie Savoureux, Fabien Vinckier, Fabrice Chrétien, Martine Gavaret, Philip Gorwood, Raphaël Gaillard, Johan Pallud

doi : 10.1093/brain/awab463

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Towards understanding genetic risk in febrile seizures: innate immunity and neuronal excitability

Heather E Olson, Annapurna Poduri

doi : 10.1093/brain/awac036

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‘Seeding’ the idea of early diagnostics in synucleinopathies

Nicole J Gallups, Ashley S Harms

doi : 10.1093/brain/awac062

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CELSR2, a new player in motor neuron axon growth and regeneration

Veselina Petrova, Sara Hakim

doi : 10.1093/brain/awac021

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Towards a coherent view of network hyperexcitability in Alzheimer’s disease

Alice D Lam, Mouhsin M Shafi

doi : 10.1093/brain/awac033

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The neuroradiology of progressive multifocal leukoencephalopathy: a clinical trial perspective

Laura E Baldassari, Mike P Wattjes, Irene C M Cortese, Achim Gass, Imke Metz, Tarek Yousry, Daniel S Reich, Nancy Richert

doi : 10.1093/brain/awab419

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Models of psychedelic drug action: modulation of cortical-subcortical circuits

Manoj K Doss, Maxwell B Madden, Andrew Gaddis, Mary Beth Nebel, Roland R Griffiths, Brian N Mathur, Frederick S Barrett

doi : 10.1093/brain/awab406

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Precision medicine in stroke: towards personalized outcome predictions using artificial intelligence

Anna K Bonkhoff, Christian Grefkes

doi : 10.1093/brain/awab439

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Stop that! It’s not Tourette’s but a new type of mass sociogenic illness

Kirsten R Müller-Vahl, Anna Pisarenko, Ewgeni Jakubovski, Carolin Fremer

doi : 10.1093/brain/awab316

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Astrocytes display cell autonomous and diverse early reactive states in familial amyotrophic lateral sclerosis

Doaa M Taha, Benjamin E Clarke, Claire E Hall, Giulia E Tyzack, Oliver J Ziff, Linda Greensmith, Bernadett Kalmar, Mhoriam Ahmed, Aftab Alam, Eric P Thelin, Nuria Marco Garcia, Adel Helmy, Christopher R Sibley, Rickie Patani

doi : 10.1093/brain/awab328

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Effect of a novel nasal oxytocin spray with enhanced bioavailability on autism: a randomized trial

Hidenori Yamasue, Masaki Kojima, Hitoshi Kuwabara, Miho Kuroda, Kaori Matsumoto, Chieko Kanai, Naoko Inada, Keiho Owada, Keiko Ochi, Nobutaka Ono, Seico Benner, Tomoyasu Wakuda, Yosuke Kameno, Jun Inoue, Taeko Harada, Kenji Tsuchiya, Kazuo Umemura, Aya Yamauchi, Nanayo Ogawa, Itaru Kushima, Norio Ozaki, Satoshi Suyama, Takuya Saito, Yukari Uemura, Junko Hamada, Yukiko Kano, Nami Honda, Saya Kikuchi, Moe Seto, Hiroaki Tomita, Noriko Miyoshi, Megumi Matsumoto, Yuko Kawaguchi, Koji Kanai, Manabu Ikeda, Itta Nakamura, Shuichi Isomura, Yoji Hirano, Toshiaki Onitsuka, Hirotaka Kosaka, Takashi Okada

doi : 10.1093/brain/awab291

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Increased expression of SLC25A1/CIC causes an autistic-like phenotype with altered neuron morphology

Michael J Rigby, Nicola Salvatore Orefice, Alexis J Lawton, Min Ma, Samantha L Shapiro, Sue Y Yi, Inca A Dieterich, Alyssa Frelka, Hannah N Miles, Robert A Pearce, John Paul J Yu, Lingjun Li, John M Denu, Luigi Puglielli

doi : 10.1093/brain/awab295

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Naming-related spectral responses predict neuropsychological outcome after epilepsy surgery

Masaki Sonoda, Robert Rothermel, Alanna Carlson, Jeong-Won Jeong, Min-Hee Lee, Takahiro Hayashi, Aimee F Luat, Sandeep Sood, Eishi Asano

doi : 10.1093/brain/awab318

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In vitro ictogenesis is stochastic at the single neuron level

Lauren A Lau, Kevin J Staley, Kyle P Lillis

doi : 10.1093/brain/awab312

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Forecasting stroke-like episodes and outcomes in mitochondrial disease

Yi Shiau Ng, Nichola Z Lax, Alasdair P Blain, Daniel Erskine, Mark R Baker, Tuomo Polvikoski, Rhys H Thomas, Christopher M Morris, Ming Lai, Roger G Whittaker, Alasdair Gebbels, Amy Winder, Julie Hall, Catherine Feeney, Maria Elena Farrugia, Claire Hirst, Mark Roberts, Charlotte Lawthom, Alexia Chrysostomou, Kevin Murphy, Tracey Baird, Paul Maddison, Callum Duncan, Joanna Poulton, Victoria Nesbitt, Michael G Hanna, Robert D S Pitceathly, Robert W Taylor, Emma L Blakely, Andrew M Schaefer, Doug M Turnbull, Robert McFarland, Gráinne S Gorman

doi : 10.1093/brain/awab353

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Genome-wide association study of febrile seizures implicates fever response and neuronal excitability genes

Line Skotte, João Fadista, Jonas Bybjerg-Grauholm, Vivek Appadurai, Michael S Hildebrand, Thomas F Hansen, Karina Banasik, Jakob Grove, Clara Albiñana, Frank Geller, Carmen F Bjurström, Bjarni J Vilhjálmsson, Matthew Coleman, John A Damiano, Rosemary Burgess, Ingrid E Scheffer, Ole Birger Vesterager Pedersen, Christian Erikstrup, David Westergaard, Kaspar René Nielsen, Erik Sørensen, Mie Topholm Bruun, Xueping Liu, Henrik Hjalgrim, Tune H Pers, Preben Bo Mortensen, Ole Mors, Merete Nordentoft, Julie W Dreier, Anders D Børglum, Jakob Christensen, David M Hougaard, Alfonso Buil, Anders Hviid, Mads Melbye, Henrik Ullum, Samuel F Berkovic, Thomas Werge, Bjarke Feenstra

doi : 10.1093/brain/awab260

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Bacterial neurotoxic metabolites in multiple sclerosis cerebrospinal fluid and plasma

Achilles Ntranos, Hye-Jin Park, Maureen Wentling, Vladimir Tolstikov, Mario Amatruda, Benjamin Inbar, Seunghee Kim-Schulze, Carol Frazier, Judy Button, Michael A Kiebish, Fred Lublin, Keith Edwards, Patrizia Casaccia

doi : 10.1093/brain/awab320

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Diagnostic value of cerebrospinal fluid alpha-synuclein seed quantification in synucleinopathies

Ilaria Poggiolini, Vandana Gupta, Michael Lawton, Seoyun Lee, Aadil El-Turabi, Agustin Querejeta-Coma, Claudia Trenkwalder, Friederike Sixel-Döring, Alexandra Foubert-Samier, Anne Pavy-Le Traon, Giuseppe Plazzi, Francesco Biscarini, Jacques Montplaisir, Jean-François Gagnon, Ronald B Postuma, Elena Antelmi, Wassilios G Meissner, Brit Mollenhauer, Yoav Ben-Shlomo, Michele T Hu, Laura Parkkinen

doi : 10.1093/brain/awab431

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Clinical and genetic spectrum of a large cohort of patients with δ-sarcoglycan muscular dystrophy

Jorge Alonso-Pérez, Lidia González-Quereda, Claudio Bruno, Chiara Panicucci, Afagh Alavi, Shahriar Nafissi, Yalda Nilipour, Edmar Zanoteli, Lucas Michielon de Augusto Isihi, Béla Melegh, Kinga Hadzsiev, Nuria Muelas, Juan J Vílchez, Mario Emilio Dourado, Naz Kadem, Gultekin Kutluk, Muhammad Umair, Muhammad Younus, Elena Pegorano, Luca Bello, Thomas O Crawford, Xavier Suárez-Calvet, Ana Töpf, Michela Guglieri, Chiara Marini-Bettolo, Pia Gallano, Volker Straub, Jordi Díaz-Manera

doi : 10.1093/brain/awab301

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Translating genetic and functional data into clinical practice: a series of 223 families with myotonia

Karen Suetterlin, Emma Matthews, Richa Sud, Samuel McCall, Doreen Fialho, James Burge, Dipa Jayaseelan, Andrea Haworth, Mary G Sweeney, Dimitri M Kullmann, Stephanie Schorge, Michael G Hanna, Roope Männikkö

doi : 10.1093/brain/awab344

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Resting-state EEG reveals four subphenotypes of amyotrophic lateral sclerosis

Stefan Dukic, Roisin McMackin, Emmet Costello, Marjorie Metzger, Teresa Buxo, Antonio Fasano, Rangariroyashe Chipika, Marta Pinto-Grau, Christina Schuster, Michaela Hammond, Mark Heverin, Amina Coffey, Michael Broderick, Parameswaran M Iyer, Kieran Mohr, Brighid Gavin, Russell McLaughlin, Niall Pender, Peter Bede, Muthuraman Muthuraman, Leonard H van den Berg, Orla Hardiman, Bahman Nasseroleslami

doi : 10.1093/brain/awab322

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Imaging protein aggregates in the serum and cerebrospinal fluid in Parkinson’s disease

Evgeniia Lobanova, Daniel Whiten, Francesco S Ruggeri, Christopher G Taylor, Antonina Kouli, Zengjie Xia, Derya Emin, Yu P Zhang, Jeff Y L Lam, Caroline H Williams-Gray, David Klenerman

doi : 10.1093/brain/awab306

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Blood DNA methylation provides an accurate biomarker of KMT2B-related dystonia and predicts onset

Nazanin Mirza-Schreiber, Michael Zech, Rory Wilson, Theresa Brunet, Matias Wagner, Robert Jech, Sylvia Boesch, Matej Škorvánek, Ján Necpál, David Weise, Sandrina Weber, Brit Mollenhauer, Claudia Trenkwalder, Esther M Maier, Ingo Borggraefe, Katharina Vill, Annette Hackenberg, Veronika Pilshofer, Urania Kotzaeridou, Eva Maria Christina Schwaibold, Julia Hoefele, Melanie Waldenberger, Christian Gieger, Annette Peters, Thomas Meitinger, Barbara Schormair, Juliane Winkelmann, Konrad Oexle

doi : 10.1093/brain/awab360

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Intravenous delivery of adeno-associated viral gene therapy in feline GM1 gangliosidosis

Amanda L Gross, Heather L Gray-Edwards, Cassie N Bebout, Nathan L Ta, Kayly Nielsen, Brandon L Brunson, Kalajan R Lopez Mercado, Devin E Osterhoudt, Ana Rita Batista, Stacy Maitland, Thomas N Seyfried, Miguel Sena-Esteves, Douglas R Martin

doi : 10.1093/brain/awab309

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Inactivating Celsr2 promotes motor axon fasciculation and regeneration in mouse and human

Quan Wen, Huandi Weng, Tao Liu, Lingtai Yu, Tianyun Zhao, Jingwen Qin, Si Li, Qingfeng Wu, Fadel Tissir, Yibo Qu, Libing Zhou

doi : 10.1093/brain/awab317

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Interactome screening of C9orf72 dipeptide repeats reveals VCP sequestration and functional impairment by polyGA

Janja Boži�, Helena Motaln, Anja Pucer Janež, Lara Marki�, Priyanka Tripathi, Alfred Yamoah, Eleonora Aronica, Youn-Bok Lee, Raphael Heilig, Roman Fischer, Andrew J Thompson, Anand Goswami, Boris Rogelj

doi : 10.1093/brain/awab300

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Diagnostic accuracy of cerebrospinal fluid biomarkers in genetic prion diseases

Matthias Schmitz, Anna Villar-Piqué, Peter Hermann, Geòrgia Escaramís, Miguel Calero, Cao Chen, Niels Kruse, Maria Cramm, Ewa Golanska, Beata Sikorska, Pawel P Liberski, Maurizio Pocchiari, Peter Lange, Christiane Stehmann, Shannon Sarros, Eulàlia Martí, Inês Baldeiras, Isabel Santana, Dana Žáková, Eva Mitrová, Xiao-Ping Dong, Steven Collins, Anna Poleggi, Anna Ladogana, Brit Mollenhauer, Gabor G Kovacs, Michael D Geschwind, Raquel Sánchez-Valle, Inga Zerr, Franc Llorens

doi : 10.1093/brain/awab350

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Cortical hypometabolism reflects local atrophy and tau pathology in symptomatic Alzheimer’s disease

Amelia Strom, Leonardo Iaccarino, Lauren Edwards, Orit H Lesman-Segev, David N Soleimani-Meigooni, Julie Pham, Suzanne L Baker, Susan M Landau, William J Jagust, Bruce L Miller, Howard J Rosen, Maria Luisa Gorno-Tempini, Gil D Rabinovici, Renaud La Joie, for the Alzheimer’s Disease Neuroimaging Initiative

doi : 10.1093/brain/awab294

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Functional protection in J20/VLW mice: a model of non-demented with Alzheimer’s disease neuropathology

Eva Dávila-Bouziguet, Arnau Casòliba-Melich, Georgina Targa-Fabra, Lorena Galera-López, Andrés Ozaita, Rafael Maldonado, Jesús �vila, José M Delgado-García, Agnès Gruart, Eduardo Soriano, Marta Pascual

doi : 10.1093/brain/awab319

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Neuronal synchrony abnormalities associated with subclinical epileptiform activity in early-onset Alzheimer’s disease

Kamalini G Ranasinghe, Kiwamu Kudo, Leighton Hinkley, Alexander Beagle, Hannah Lerner, Danielle Mizuiri, Anne Findlay, Bruce L Miller, Joel H Kramer, Maria Luisa Gorno-Tempini, Gil D Rabinovici, Katherine P Rankin, Paul A Garcia, Heidi E Kirsch, Keith Vossel, Srikantan S Nagarajan

doi : 10.1093/brain/awab442

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Sensory processing dysregulations as reliable translational biomarkers in SYNGAP1 haploinsufficiency

Maria Isabel Carreño-Muñoz, Bidisha Chattopadhyaya, Kristian Agbogba, Valérie Côté, Siyan Wang, Maxime Lévesque, Massimo Avoli, Jacques L Michaud, Sarah Lippé, Graziella Di Cristo

doi : 10.1093/brain/awab329

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Regulatory variants at 2q33.1 confer schizophrenia risk by modulating distal gene TYW5 expression

Shiwu Li, Jiao Li, Jiewei Liu, Junyang Wang, Xiaoyan Li, Yongxia Huo, Yifan Li, Yixing Liu, Ming Li, Xiao Xiao, Xiong-Jian Luo

doi : 10.1093/brain/awab357

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Cerebrospinal fluid is a significant fluid source for anoxic cerebral oedema

Ting Du, Humberto Mestre, Benjamin T Kress, Guojun Liu, Amanda M Sweeney, Andrew J Samson, Martin Kaag Rasmussen, Kristian Nygaard Mortensen, Peter A R Bork, Weiguo Peng, Genaro E Olveda, Logan Bashford, Edna R Toro, Jeffrey Tithof, Douglas H Kelley, John H Thomas, Poul G Hjorth, Erik A Martens, Rupal I Mehta, Hajime Hirase, Yuki Mori, Maiken Nedergaard

doi : 10.1093/brain/awab293

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Poor statistical reporting in a spinal cord injury clinical trial

Martin E Héroux, Euan McCaughey, Simon C Gandevia

doi : 10.1093/brain/awab471

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Reply: Poor statistical reporting in a spinal cord injury clinical trial

Masao Koda

doi : 10.1093/brain/awab468

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Corrigendum to: UNC13B variants associated with partial epilepsy with favourable outcome

doi : 10.1093/brain/awab427

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