Xiaoqiu YuanLei ShiYu Chen
doi : 10.1007/s00586-020-06687-y
Volume 30, issue 4, April 2021, Pages: 801 - 808
Ossification of the spinal ligament (OSL) is a disease characterized by progressive ectopic ossification or calcification in the tissues of spinal ligament. The molecular pathogenesis of OSL has not been clearly elucidated. Recently, ncRNAs was found to functionally participate in OSL development. This review summarized current knowledge regarding the deregulation and function of ncRNAs in OSL
Vicki M. ButenschoenHanna HitscherichMaria Wostrack
doi : 10.1007/s00586-021-06726-2
Volume 30, issue 4, April 2021, Pages: 809 - 817
Spinal diseases requiring urgent surgical treatment are rare during pregnancy. Evidence is sparse and data are only available in the form of case reports. Our aim is to provide a comprehensive guide for spinal surgery on pregnant patients and highlight diagnostic and therapeutic aspects.
Weishi LiangBo HanCongying Zou
doi : 10.1007/s00586-020-06556-8
Volume 30, issue 4, April 2021, Pages: 818 - 828
This study aimed to investigate the diagnostic value of fractional anisotropy (FA) and apparent diffusion coefficient (ADC) of the diffusion tensor imaging (DTI) with fiber tracking in patients with compressed lumbosacral nerve roots.
Hideaki NakajimaShuji WatanabeAkihiko Matsumine
doi : 10.1007/s00586-020-06485-6
Volume 30, issue 4, April 2021, Pages: 829 - 836
Symptomatic thoracic disc herniation (TDH) is relatively rare, but patients with progressive myelopathy require surgical treatment without delay in diagnosis. The aim of this study was to review clinical and radiological features in patients with TDH presenting with myelopathy.
Greg JamesXiaolong ChenPaul W. Hodges
doi : 10.1007/s00586-020-06514-4
Volume 30, issue 4, April 2021, Pages: 837 - 845
Recent animal studies have discovered dysregulation of local inflammatory activity as a novel mechanism to explain fat and connective tissue accumulation in the multifidus muscle in association with intervertebral disc (IVD) degeneration/injury. This study aimed to test whether similar mechanisms are active in humans by investigation of whether expression of inflammatory genes in the multifidus muscle differed between individuals with low and high levels of intra-muscular fat in the muscle. The secondary aims were to compare inflammatory gene expression in the intra-muscular, subcutaneous and epidural fat between groups.
Fergus J. McCabeDavid M. DaltonJohn P. McCabe
doi : 10.1007/s00586-020-06691-2
Volume 30, issue 4, April 2021, Pages: 846 - 854
Bias undermines evidence-based decision making. To counter this, surgeons must be aware of biases that may influence studies’ reported outcomes. Lumbar spinal stenosis often requires operative intervention, with multiple available surgical strategies. Our aim was to assess the role that country of origin plays in published surgical outcomes for lumbar spinal stenosis.
Chao KongXiang-Yu LiShi-Bao Lu
doi : 10.1007/s00586-020-06600-7
Volume 30, issue 4, April 2021, Pages: 855 - 864
To investigate the diagnostic value of contrast-enhanced three-dimensional (3D) T2-weighted turbo spin-echo SPACE (T2-SPACE) sequence in LNRC.
S. HaleemM. MalikR. Botchu
doi : 10.1007/s00586-020-06656-5
Volume 30, issue 4, April 2021, Pages: 865 - 869
No clinical CT-based classification system is currently in use for lumbar foraminal stenosis. MRI scanners are not easily available, are expensive and may be contraindicated in an increasing number of patients. This study aimed to propose and evaluate the reproducibility of a novel CT-based classification for lumbar foraminal stenosis.
Jayme C. B. KoltsovMatthew W. SmuckSerena S. Hu
doi : 10.1007/s00586-020-06566-6
Volume 30, issue 4, April 2021, Pages: 870 - 877
The study objectives were to use a large national claims data resource to examine rates of preoperative epidural steroid injections (ESI) in lumbar spine surgery and determine whether preoperative ESI or the timing of preoperative ESI is associated with rates of postoperative complications and reoperations.
Alexander ChyeChung-Wei Christine LinBlake Angell
doi : 10.1007/s00586-020-06605-2
Volume 30, issue 4, April 2021, Pages: 878 - 885
To estimate the healthcare resource utilisation of an Australian cohort of people with sciatica and explore individual-level factors associated with expenditure.
Hang ShiLei ZhuXiao-Tao Wu
doi : 10.1007/s00586-020-06674-3
Volume 30, issue 4, April 2021, Pages: 886 - 892
To investigate radiological risk factors for recurrent lumbar disc herniation (rLDH) after percutaneous transforaminal endoscopic discectomy (PTED).
Alessandro SiccoliMarc L. Schr?derVictor E. Staartjes
doi : 10.1007/s00586-020-06692-1
Volume 30, issue 4, April 2021, Pages: 893 - 898
Recurrent lumbar disc herniation (LDH) is the most frequent reason for reoperation after lumbar microdiscectomy. While several risk factors for recurrent LDH have been well-described, the effect of age on recurrence remains unclear, especially concerning the timing of recurrent LDH.
Taro InoueKei AndoShiro Imagama
doi : 10.1007/s00586-020-06693-0
Volume 30, issue 4, April 2021, Pages: 899 - 906
Tandem spinal stenosis (TSS) refers to coexisting lumbar and cervical canal stenosis. Evidence regarding whether cervical decompression improves lumbar symptoms in TSS is insufficient. Therefore, we determined the effectiveness of cervical decompression surgery for patients with lumbar spinal stenosis (LSS) and cervical spinal stenosis.
Anne F. MannionFrancine MariauxFrançois Porchet
doi : 10.1007/s00586-021-06725-3
Volume 30, issue 4, April 2021, Pages: 907 - 917
Treatment failures in spine surgery are often attributable to poor patient selection and the application of inappropriate treatment. We used published appropriate use criteria (AUC) to evaluate the appropriateness of surgery in a large group of patients operated for lumbar degenerative spondylolisthesis (LDS) and to evaluate its association with outcome.
Hiromitsu ToyodaKentaro YamadaHiroaki Nakamura
doi : 10.1007/s00586-021-06754-y
Volume 30, issue 4, April 2021, Pages: 918 - 927
Residual symptoms indicating incomplete remission of lower leg numbness or low back pain may occur after spine surgery. The purpose was to elucidate the pattern of residual symptoms 5 years after minimally invasive lumbar decompression surgery using a cluster analysis.
Maria Adriano CostaPedro Santos SilvaPaulo Pereira
doi : 10.1007/s00586-020-06639-6
Volume 30, issue 4, April 2021, Pages: 928 - 935
The aim of this study is to determine if there is a relation between preoperative sagittal alignment, based on radiographic parameters, and clinical outcomes, after lumbar decompressive procedures, in patients with lumbar spinal stenosis (LSS).
Tamara HeroldRalph KotheKarin Wuertz-Kozak
doi : 10.1007/s00586-021-06765-9
Volume 30, issue 4, April 2021, Pages: 936 - 945
Decompression is one of the most common interventions in spinal surgery. Obesity has become an increasing issue in surgical patients. Therefore, the aim of this study was to analyze the clinical outcome following lumbar microsurgical decompression in correlation with the patient’s body mass index (BMI).
Agnieszka K?draMagdalena PlandowskaDariusz Czaprowski
doi : 10.1007/s00586-020-06575-5
Volume 30, issue 4, April 2021, Pages: 946 - 956
Due to a high prevalence of low back pain (LBP) among children and adolescents, it is significant to seek effective prevention and therapeutic procedures. One idea for the programmes is a potential relation between the occurrence of LBP and the level of physical activity. The aim of this review was to analyse the current knowledge regarding the association between physical activity and LBP among children and adolescents.
Ahmed Omar AbdelnaeemAliaa Rehan YoussefRobert Vining
doi : 10.1007/s00586-020-06712-0
Volume 30, issue 4, April 2021, Pages: 957 - 989
To identify and critically appraise studies evaluating psychometric properties of functionally oriented diagnostic classification systems for Non-Specific Chronic Low Back Pain (NS-CLBP).
Simon LafranceJean-Gabriel LapalmeFrançois Desmeules
doi : 10.1007/s00586-020-06648-5
Volume 30, issue 4, April 2021, Pages: 990 - 1003
To appraise the available evidence on advanced practice physiotherapy (APP) models of care (MoC) in specialized secondary care such as orthopaedic, rheumatology or neurosurgery outpatients’ clinics for adults with spinal pain.
Rajani MullerpatanShweta NaharMargareta Nordin
doi : 10.1007/s00586-020-06585-3
Volume 30, issue 4, April 2021, Pages: 1004 - 1010
Among non-communicable disorders, low back and neck pain are the most common causes of severe, long-term pain and disability affecting more than a billion people globally. Yet, the burden and impact of these conditions are not well understood, especially among rural and tribal people living in low- and middle-income countries.
Yoshimasa MeraMasatoshi TeraguchiHiroshi Yamada
doi : 10.1007/s00586-020-06618-x
Volume 30, issue 4, April 2021, Pages: 1011 - 1017
The clinical significance of Modic changes in low back pain (LBP) is yet to be clarified. Thus, this study aimed to examine the association between Modic changes and LBP after adjustment for confounding factors.
Jaro KarppinenKatri KoivistoSibylle Grad
doi : 10.1007/s00586-020-06713-z
Volume 30, issue 4, April 2021, Pages: 1018 - 1027
Lumbar Modic change (MC) can serve as a diagnostic marker as well as an independent source of chronic low back pain (CLBP). This study aimed to test for the existence of serum biomarkers in CLBP patients with MC.
Amber M BeynonJeffrey J HebertBruce F Walker
doi : 10.1007/s00586-020-06677-0
Volume 30, issue 4, April 2021, Pages: 1028 - 1034
To identify low back pain (LBP) trajectories from early adolescence through to early adulthood and to investigate whether sustained levels of elevated subclinical C-reactive protein (CRP) are linked with these LBP trajectories.
Erica Beaucage-GauvreauScott C. E. BrandonClaire F. Jones
doi : 10.1007/s00586-020-06631-0
Volume 30, issue 4, April 2021, Pages: 1035 - 1042
To evaluate the effect of the braced arm-to-thigh technique (BATT) (versus self-selected techniques) on three-dimensional trunk kinematics and spinal loads for three common activities of daily living (ADLs) simulated in the laboratory: weeding (gardening), reaching for an object in a low cupboard, and car egress using the two-legs out technique.
Ellen CoeckelberghsHilde VerbekeBart Depreitere
doi : 10.1007/s00586-020-06675-2
Volume 30, issue 4, April 2021, Pages: 1043 - 1052
Low back pain (LBP) is a major public health problem worldwide. Significant practice variation exists despite guidelines, including strong interventionist focus by some practitioners. Translation of guidelines into pathways as integrated treatment plans is a next step to improve implementation. The goal of the present study was to analyze international examples of LBP pathways in order to identify key interventions as building elements for care pathway for LBP and radicular pain.
Phedy PhedyYoshi Pratama DjajaNicko Perdana Hardiansyah
doi : 10.1007/s00586-020-06690-3
Volume 30, issue 4, April 2021, Pages: 1053 - 1062
The Oswestry Disability Index (ODI) is one of the most common patient-reported outcome measures used for low back pain (LBP). Since it was not available in Indonesian, this study aimed to perform a cross-cultural adaptation of ODI to Indonesian and evaluate its psychometric properties.
Li LiZhiguo ZhouKejia Cai
doi : 10.1007/s00586-021-06733-3
Volume 30, issue 4, April 2021, Pages: 1063 - 1071
Z-spectral MRI data were analyzed to produce multiparametric metabolic and microenvironmental contrasts for identifying intervertebral discs with/without pain symptom and sore pain.
R. HochgattererM. GahleitnerL. Pisecky
doi : 10.1007/s00586-020-06627-w
Volume 30, issue 4, April 2021, Pages: 1072 - 1076
We aim to critically review the effectiveness and safety of coccygectomy with special regard to long-term outcomes.
Sarah RazaqMurat KaraLevent ?zçakar
doi : 10.1007/s00586-021-06735-1
Volume 30, issue 4, April 2021, Pages: 1077 - 1077
Hirokazu InoueHideaki WatanabeKatsushi Takeshita
doi : 10.1007/s00586-021-06736-0
Volume 30, issue 4, April 2021, Pages: 1078 - 1080
Chongqing XuMengchen Yin
doi : 10.1007/s00586-021-06788-2
Volume 30, issue 4, April 2021, Pages: 1081 - 1082
Bertrand Debono
doi : 10.1007/s00586-021-06791-7
Volume 30, issue 4, April 2021, Pages: 1083 - 1084
Scott BlumenthalAshish D. Diwan
doi : 10.1007/s00586-020-06708-w
Volume 30, issue 4, April 2021, Pages: 1085 - 1086
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