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Fibromyalgia and psoriatic arthritis: Partners together
Geoffrey Owen Littlejohn
doi : 10.1111/1756-185X.14029
Volume 24, Issue 2 p. 141-143
Emerging COVID?19 vaccines: A rheumatology perspective
Swetha Byravan Armin Fardanesh Hasan Tahir Arumugam Moorthy
doi : 10.1111/1756-185X.14048
Volume 24, Issue 2 p. 144-146
Association of MBL2 gene polymorphisms and systemic lupus erythematosus susceptibility: A meta?analysis
Zhi?Chao Yuan Wang?Dong Xu You?Yu Lan Jia?Min Wang Qian Wu Jie Zhou An?Fang Huang
doi : 10.1111/1756-185X.14017
Volume 24, Issue 2 p. 147-158
Mannose binding lectin (MBL) gene single nucleotide polymorphisms have been associated with systemic lupus erythematosus (SLE) risk with inconsistent results. This study aimed to explore whether MBL2 A\B, A\C, A\D, A\O, L\H and Y\X polymorphisms affected SLE susceptibility.
Role of exosome in autoimmunity, with a particular emphasis on rheumatoid arthritis
Alireza Hejrati Bahare Hasani Mozhgan Esmaili Davood Bashash Naeimeh Tavakolinia Parisa Zafari
doi : 10.1111/1756-185X.14021
Volume 24, Issue 2 p. 159-169
Cell?derived exosomes are identified as carriers of lipids, proteins, and genetic materials that participate in cell?cell signal communication, biological process, and cell signaling. Also, their involvement has been reported in a vast array of disorders and inflammatory conditions such as autoimmune diseases. Rheumatoid arthritis (RA), a common cause of joint disorder, is an inflammation?based disease in which the precise understanding of its pathogenesis needs to be further investigated. Also, there is only a palliative care approach for the alleviation of RA symptoms. This paper discusses the recent advances in the biology of exosomes in autoimmune disorders especially in RA, and also provides a new line of research for arthritis therapy using exosomes.
Therapeutic exercises and rehabilitation in axial spondyloarthropathy: Balancing benefits with unique challenges in the Asia?Pacific countries
Parthajit Das Rathindranath Haldar Sham Santhanam Vinod Ravindran
doi : 10.1111/1756-185X.14035
Volume 24, Issue 2 p. 170-182
The burden of axial spondyloarthropathy (axSpA) in the Asia?Pacific region is substantial. The management of axSpA has been revolutionized with the advent of biological therapy where the disease activity, functional disability and negative psychological affect can be mitigated to a great extent. On the other hand, exercise remains an essential component of the treatment of axSpA at all stages, which is often discounted or underused. This is compounded by a gap in demand and supply between increasing number patients with axSpA and paucity of trained specialists and rehabilitation personnel in the Asia?Pacific countries. The acceptability and uptake of therapeutic exercise is strikingly poor in this region because of multiple factors such as lack of awareness among health professionals and the general population, poor healthcare infrastructure, lack of resources and limited accessibility to rehabilitation services. Health authorities and professional bodies in these countries need to work in tandem to expand healthcare facilities, encourage training opportunities and promote safe and effective exercise interventions which is accessible to the general population and individuals with axSpA. Adequate patient education, optimum control of disease activity and strict adherence to therapeutic exercise is essential to predict the best clinical outcome. In this narrative review we have appraised the impact of therapeutic exercise in this era of biological therapies in axSpA and have explored the challenges of rehabilitation services in the Asia?Pacific countries. Overall, the available quality of evidence is mixed, acknowledging the beneficial role of exercise and optimum usage and protocols pertaining to axSpA specific exercises and therefore further research is warranted.
Fibromyalgia in patients with psoriatic arthritis: Relationship with enthesopathy, sleep, fatigue and quality of life
Firat Ulutatar Cagri Unal?Ulutatar Mehmet Tuncay Duruoz
doi : 10.1111/1756-185X.13963
Volume 24, Issue 2 p. 183-188
To evaluate the relationship of fibromyalgia with enthesopathy, sleep, fatigue and quality of life in patients with psoriatic arthritis.
Fibromyalgia in patients with psoriatic arthritis: Impact on disease activity indices, fatigue and health?related quality of life
Noha A. Elsawy Abdel?Moneim H. Helal Hala A. Abd ElHamid Yousra Hisham Abdel?Fattah
doi : 10.1111/1756-185X.13987
Volume 24, Issue 2 p. 189-196
To assess the frequency of fibromyalgia (FM) in patients with psoriatic arthritis (PsA) and its impact on disease activity indices, fatigue and health?related quality of life (QOL).
YouTube as a source of information on fibromyalgia
Tugba Ozsoy?Unubol Ebru Alanbay?Yagci
doi : 10.1111/1756-185X.14043
Volume 24, Issue 2 p. 197-202
The internet has gained popularity as a health information source for patients. YouTube is one of the biggest platforms used worldwide. Several studies showed that quality of the information on YouTube videos for patient information is poor. This study aimed to evaluate the content and quality of YouTube videos, as a source of patient information for fibromyalgia (FM).
Did Sejong the Great have ankylosing spondylitis? The oldest documented case of ankylosing spondylitis
JiHwan Lee
doi : 10.1111/1756-185X.14025
Volume 24, Issue 2 p. 203-206
Sejong the Great (May 7, 1397?March 30, 1450), a king during Korea's Choson Dynasty, is the most respected historical figure in South Korean society, and consequently, many studies have been conducted on his achievements and the disease he suffered. The dominant trend of scholarship claims that Sejong suffered from diabetic retinopathy. However, this interpretation has not been medically verified. The present analysis aimed to demonstrate that Sejong's is the oldest documented case of ankylosing spondylitis.
Prevalence of inflammatory back pain and radiographic axial spondyloarthritis in a semi?urban community of Lahore, Pakistan
Muhammad Ahmed Saeed Hina Ahmed Muhammad Faiq Zeeshan Aslam Saira Elaine Anwer Khan Shabnam Batool Sumaira Farman Nighat Mir Ahmad
doi : 10.1111/1756-185X.14030
Volume 24, Issue 2 p. 207-215
To determine the prevalence of inflammatory back pain (IBP) and radiographic axial spondyloarthritis (SpA) in a semi?urban community of Lahore, Pakistan.
Cancer diagnosis and mortality in patients with ankylosing spondylitis: A Western Australian retrospective cohort study
Erin Kelty Warren Raymond Charles Inderjeeth Helen Keen Johannes Nossent David B. Preen
doi : 10.1111/1756-185X.14036
Volume 24, Issue 2 p. 216-222
Ankylosing spondylitis (AS) has been associated with a modest increase in the risk of cancer. However, little is known as to how AS influences risk of mortality following cancer diagnosis. This study compared the risk of cancer and subsequent mortality in patients with AS compared with a non?AS population group.
Assessment of loneliness in patients with inflammatory arthritis
Hakan Emmungil Ufuk ?lgen Sezin Turan Ozge Kilic
doi : 10.1111/1756-185X.14041
Volume 24, Issue 2 p. 223-230
This study aimed to explore loneliness and associated factors in Turkish patients with inflammatory arthritis.
Higher serum levels of autotaxin and phosphatidylserine?specific phospholipase A1 in patients with lupus nephritis
Yasunori Iwata Shinji Kitajima Junya Yamahana Shuji Shimomura Shiori Yoneda?Nakagawa Norihiko Sakai Kengo Furuichi Hisayuki Ogura Koichi Sato Tadashi Toyama Yuta Yamamura Taro Miyagawa Akinori Hara Miho Shimizu Ryunosuke Ohkawa Makoto Kurano Yutaka Yatomi Takashi Wada
doi : 10.1111/1756-185X.14031
Volume 24, Issue 2 p. 231-239
Recent studies revealed that lysophospholipids (LPLs) and related molecules, such as autotaxin (ATX) and phosphatidylserine?specific phospholipase A1 (PS?PLA1), are candidates for novel biomarkers in melanoma, glaucoma and diabetic nephropathy. However, it is not clear whether serum levels of ATX/ PS?PLA1 would be associated with pathological and clinical findings of lupus nephritis (LN).
Association between Graves' disease and risk of incident systemic lupus erythematosus: A nationwide population?based cohort study
Cho Lee Shih?Fen Chen Yu?Cih Yang Chung Y. Hsu Yu?Chih Shen
doi : 10.1111/1756-185X.14027
Volume 24, Issue 2 p. 240-245
Previous case reports have linked Graves' disease to incident systemic lupus erythematosus (SLE). It has also been reported that antithyroid drugs used to treat Graves' disease can induce SLE development. The purpose of this study was to investigate the risk of SLE in patients with Graves' disease.
Relationships of the stand?up time to falls and fractures in patients with rheumatoid arthritis: Results from the CHIKARA study
Patients with rheumatoid arthritis (RA) have a higher risk of falls and fractures due to muscle weakness and painful joints of the lower extremities. Evaluation of muscle functions is important to predict falls and fractures. The aim was to investigate the relationships of muscle functions with falls and fractures in RA patients.
doi : 10.1111/1756-185X.14033
Volume 24, Issue 2 p. 246-253
Patients with rheumatoid arthritis (RA) have a higher risk of falls and fractures due to muscle weakness and painful joints of the lower extremities. Evaluation of muscle functions is important to predict falls and fractures. The aim was to investigate the relationships of muscle functions with falls and fractures in RA patients.
Risk of hepatitis B reactivation in patients receiving anti?tumor necrosis factor?? therapy
Sami Fidan Erhan Capk?n Deniz Aksu Ar?ca Serdar Durak Ilyas Ercan Okatan
doi : 10.1111/1756-185X.14034
Volume 24, Issue 2 p. 254-259
The purpose of this study was to determine hepatitis B virus (HBV) screening rates in patients receiving anti?tumor necrosis factor (TNF)?? therapy and the frequency of HBV reactivation in patients with resolved hepatitis B virus infection (hepatitis B surface antigen [HBsAg] negative, hepatitis B core antibody [Anti?HBc] positive).
Association of serum CXCL12 levels with arthropathy in patients with systemic sclerosis
Tetsuya Ikawa Takuya Miyagawa Yuki Fukui Satoshi Toyama Jun Omatsu Kentaro Awaji Yuta Norimatsu Yusuke Watanabe Ayumi Yoshizaki Shinichi Sato Yoshihide Asano
doi : 10.1111/1756-185X.14037
Volume 24, Issue 2 p. 260-267
Systemic sclerosis (SSc) is an autoimmune connective tissue disease, in which extensive fibrotic change and vasculopathy affect the skin and various internal organs. It also involves the joints, causing stiffness, arthralgia, and arthritis. Although arthropathy is commonly observed in SSc, its underlying mechanism remains unknown. CXCL12, also known as stromal cell derived factor 1, is associated with inflammation, mesenchymal cell recruitment, angiogenesis, and collagen production, and is implicated in the development of various joint diseases. To assess the potential contribution of CXCL12 to SSc development, we investigated the clinical association of serum CXCL12 levels in patients with SSc.
Risk factors for cancer?associated myositis: A large?scale multicenter cohort study
Yimin Li Xiaohui Jia Xiaolin Sun Lianjie Shi Fuan Lin Yuzhou Gan Xuewu Zhang Xiaojuan Gao Miao Miao Daojun Hong Yuhui Li Jing He
doi : 10.1111/1756-185X.14046
Volume 24, Issue 2 p. 268-273
The aim of this study was to identify the risk factors and prognosis of patients with cancer?associated myositis (CAM).
Recent advances in pediatric rheumatology: July to September 2020
Sathish Kumar Loganathan Sanjib Mondal Surjit Singh
doi : 10.1111/1756-185X.14047
Volume 24, Issue 2 p. 274-277
Are down?titration and discontinuation strategies of tumour necrosis factor–blocking agents for rheumatoid arthritis in patients with low disease activity possible? ? A Cochrane Review summary with commentary
Giovanni Morone
doi : 10.1111/1756-185X.13989
Volume 24, Issue 2 p. 278-280
The association between gout and the risk of urological cancers: A pooled analysis of population?based studies
Dechao Feng Xiao Hu Yubo Yang Lu Yang Wuran Wei
doi : 10.1111/1756-185X.14044
Volume 24, Issue 2 p. 281-283
C?reactive protein concentrations as predictors of glucocorticoid?free remission in patients with polymyalgia rheumatica
Ciro Manzo
doi : 10.1111/1756-185X.14054
Volume 24, Issue 2 p. 284-285
Your help is needed in the fight against COVID?19: Please contribute to the COVID?19 Global Rheumatology Alliance registry
doi : 10.1111/1756-185X.14073
Volume 24, Issue 2 p. 286-286
