Radiotherapy and Oncology




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GEC-ESTRO ACROP prostate brachytherapy guidelines

AnnHenryaBradley R.PietersbFrankAndré SiebertcPeterHoskindeon behalf of the UROGEC group of GEC ESTRO with endorsement by the European Association of Urology1

doi : 10.1016/j.radonc.2021.12.047

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Chemoradiotherapy with temozolomide vs. radiotherapy alone in patients with IDH wild-type and TERT promoter mutation WHO grade II/III gliomas: A prospective randomized study

XiaoguangQiua1YidongChend1ZhaoshiBaobcLiChenaTaoJiangbc

doi : 10.1016/j.radonc.2021.12.009

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Re-irradiation for recurrent high grade glioma (HGG) patients: Results of a single arm prospective phase 2 study

PierinaNavarriaaFedericoPessinabeElenaClericiaLuisaBelluaCiroFranzeseaeAndreaFranzinibMatteoSimonelliceLorenzoBellohArmandoSantoroceLetterio SalvatorePolitideGiuseppe RobertoD'agostinoaAlessandraCasarottibBethaniaFernandesfValterTorrigMartaScorsettiae

doi : 10.1016/j.radonc.2021.12.019

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Urethral and bladder dose–effect relations for late genitourinary toxicity following external beam radiotherapy for prostate cancer in the FLAME trial

Veerle H.GroenaMarcelvan SchiebNicolaas P.A.ZuithoffcEvelyn M.MonninkhofcMartinaKunze-BuschdJohannes C.J.de BoeraJochemvan der Voort van ZijpaFloris J.PosbRobert JanSmeenkdKarinHaustermanseSofieIsebaerteCédricDraulanseTomDepuydteHelena M.VerkooijenfUulke A.van der HeidebLinda G.W.Kerkmeijerad

doi : 10.1016/j.radonc.2021.12.027

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Whole lung irradiation as a novel treatment for COVID-19: Final results of the prospective randomized trial (WINCOVID trial)

GovindarajGanesanaSasipriyaPonniahaVivekSundarambPraveen KumarMarimuthuaVenkatramanPitchaikannuaManikandanChandrasekaranaJanakiramanThangarasucGunasekaranKannupaiyanaPrabhuRamamoorthyaBrindhaThangarajaHarshavardhanan SasipriyaGovindarajaShree VaishnaviRagurama

doi : 10.1016/j.radonc.2021.12.024

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Dosimetric impact of interfraction prostate and seminal vesicle volume changes and rotation: A post-hoc analysis of a phase III randomized trial of MRI-guided versus CT-guided stereotactic body radiotherapy

Ting MartinMaaJackNeylonaMariaCasadoaSahilSharmaaKeShengaDanielLowaYingliYangaMichael L.SteinbergaJamesLambaMinsongCaoa1Amar U.Kishanab1

doi : 10.1016/j.radonc.2021.12.037

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LITE SABR M1: A phase I trial of Lattice stereotactic body radiotherapy for large tumors

SaiDurisetiJames A.KavanaughJeffSzymanskiYiHuangFrancoBasarabescuAadelChaudhuriLaurenHenkePamelaSamsonAlexanderLinCliffordRobinsonMatthew B.Spraker

doi : 10.1016/j.radonc.2021.11.023

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Current practice in proton therapy delivery in adult cancer patients across Europe

MakbuleTambasaHans Paulvan der LaanaRoel J.H.M.SteenbakkersaJeromeDoyenbBeateTimmermanncdEsterOrlandieMortenHoyerfKarinHaustermansgPetraGeorghNeil GBurnetiVincentGregoirejValentinCalugarukEsther G.C.TroostlmnopqrFrankHoeberssFelipe A.CalvotJoachimWidderuFabianEberlevMarcovan Vulpenw…Johannes A.Langendijka

doi : 10.1016/j.radonc.2021.12.004

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Implementation of MR-linac and proton therapy in two radiotherapy departments in The Netherlands: Recommendations based on lessons learned

MariaJacobsaLindaKerkmeijerbDirkde RuysschercEllenBrunenbergbLiesbethBoersmacMarcelVerheijb

doi : 10.1016/j.radonc.2021.12.007

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Men’s preferences for image-guidance in prostate radiation therapy: A discrete choice experiment

AmyBrownabTilleyPainabAlexTanabLuxAnableaEmilyCallandercbKerrianneWattbDeborahStreetdRichardDe Abreu Lourencod

doi : 10.1016/j.radonc.2021.11.032

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Provincial variations in radiotherapy utilization as a measure of access: A pan-Canadian study

JessicaChanabErikaBrowncKristopherDennisdMichaelMiloseviceMichaelBrundagef

doi : 10.1016/j.radonc.2021.12.017

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Post-operative re-irradiation with hyperthermia in locoregional breast cancer recurrence: Temperature matters

AkkeBakkera1C. PaolaTello Valverdea1Geertjanvan TienhovenaM. WillemijnKolffaH. PetraKokaBen J.SlotmanaInge R.H.M.KoningsbArlene L.OeiacHester S.A.OldenburgdEmiel J.T.RutgersdCoen R.N.RascheH.J.G. Desiréevan den Bongarda2HansCrezeea2

doi : 10.1016/j.radonc.2021.12.036

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Radiation induced contrast enhancement after proton beam therapy in patients with low grade glioma – How safe are protons?

Semi B.HarrabiabcdeBastianvon NettelbladtacdClemensGuddenaSebastianAdebergacdKatharinaSeidensaalacdJuliaBauerbcdEmanuelBahnacdeAndreaMairanibgMarkusAlberacdThomasHabererbJuergenDebusabcdefKlausHerfarthabcd

doi : 10.1016/j.radonc.2021.12.035

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Non-invasive preoperative imaging differential diagnosis of pineal region tumor: A novel developed and validated multiparametric MRI-based clinicoradiomic model

YanghuaFan1XuleiHuo1XiaojieLiLiangWangZhenWu

doi : 10.1016/j.radonc.2022.01.005

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Late cardiac toxicity of neo-adjuvant chemoradiation in esophageal cancer survivors: A prospective cross-sectional pilot study

Jannet C.Beukemaa1Crystalde Grootb1John T.M.PlukkercRozemarijnVliegenthartdJohannes A.LangendijkaPetervan LuijkaJoost P.van MelleeNiek H.J.PrakkendChristina T.Muijsa

doi : 10.1016/j.radonc.2021.11.029

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Collagen score in the tumor microenvironment predicts the prognosis of rectal cancer patients after neoadjuvant chemoradiotherapy

XiaoyuDongab1YingHuangc1XianYua1MingjinHuangcWeiJiangaDexinChenaGuangxingWangbShuangmuZhuobPanChicJunYana

doi : 10.1016/j.radonc.2021.12.023

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An analysis of a large multi-institutional database reveals important associations between treatment parameters and clinical outcomes for stereotactic body radiotherapy (SBRT) of oligometastatic colorectal cancer

SaadSheikhaHanboChenbArjunSahgalbIanPoonbDarbyErlerbSerenaBadellinocRoiDagandMatthew C.FooteeAlexander V.LouiebKristin J.RedmondfUmbertoRicardicTithiBiswasa

doi : 10.1016/j.radonc.2021.12.018

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Evaluation of prognostic factors after primary chemoradiotherapy of anal cancer: A multicenter study of the German Cancer Consortium-Radiation Oncology Group (DKTK-ROG)

D.MartinabcT.SchreckenbachdP.ZieglerbceN.FilmannfG.KalinauskaiteghI.TinhoferghV.BudachghC.GaniijD.ZipsijT.Schimek-JaschklH.SchäferklA.L.GrosuklE.ThomasmnoprM.KrausemnopqrH.DapperstS.CombsstC.HoffmannuvM.Stuschkeuv…E.Fokasabc

doi : 10.1016/j.radonc.2021.12.050

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Fewer head and neck cancer diagnoses and faster treatment initiation during COVID-19 in 2020: A nationwide population-based analysis

Rosanne C.Schoonbeeka1Dominique V.C.de Jelbc1Boukje A.C.van DijkdeStefan M.WillemsfElisabethBloemenagFrank J.P.HoebershEsthervan MeerteniBerit M.VerbistjLudi E.SmeeleckGyörgy B.HalmosaMatthias A.W.MerkxdlSabineSieslingdmRemcoDe BreenRobert P.Takesoon behalf of the Dutch Head, Neck Society, the COVID, Cancer-NL consortium

doi : 10.1016/j.radonc.2021.12.005

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Relationship between oral mucositis and the oral bacterial count in patients with head and neck cancer undergoing carbon ion radiotherapy: A prospective study

AtsushiMushaab1ChikaHiraiaYokoKitadaaAnnaTsunodaaHirofumiShimadaaNobuteruKuboaHidemasaKawamuraaNaokoOkanoaHiroSatoaKoheiOkadaaAkikoAdachiaSatoshiYokoobKazuakiChikamatsucTatsuyaOhnoa

doi : 10.1016/j.radonc.2021.12.010

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Incidence and prognostic significance of extranodal extension in isolated nodal recurrence of oral squamous cell carcinoma

Chun-WeiChangaChiWangbChi-JuLucChun-WeiWangdChen-TuWuefCheng-PingWangaTsung-LinYangaPei-JenLouaJenq-YuhKoaYih-LeongChangefTseng-ChengChena

doi : 10.1016/j.radonc.2021.12.008

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Identifying optimal clinical trial candidates for locoregionally advanced nasopharyngeal carcinoma: Analysis of 9468 real-world cases and validation by two phase 3 multicentre, randomised controlled trial

Si-QiTanga1LeiChena1Wen-FeiLia1Anthony T.C.ChanbShao HuiHuangcMelvin L.K.ChuadeBrianO'SullivancAnne W.M.LeefgNancy Y.LeehYuanZhangaYu-PeiChenaChengXuaYingSunaLing-LongTangaJunMaa

doi : 10.1016/j.radonc.2021.12.029

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Level Ib sparing intensity-modulated radiation therapy in selected nasopharyngeal carcinoma patients based on the International Guideline

QiaojuanGuoabc1NanXiaoa1HanchuanXuaJingfengZongaYoupingXiaodTianzhuLueYunXuaBingyiWangaBijuanChenaJianjiPanabShaojunLinab

doi : 10.1016/j.radonc.2021.12.032

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Impact of salvage radiotherapy on survival of patients with advanced locally recurrent nasopharyngeal carcinoma: Derivation and validation of a predictive model

TingLiuab1Bo-WenShenc1Li-TingLiuab1Zhen-ChongYangab1Shi-QianWangc1Da-FengLinabXue-SongSunabShan-ShanGuoabSai-LanLiuabMei-JuanLuoabQiu-YanChenabLin-QuanTangabHai-QiangMaiab

doi : 10.1016/j.radonc.2021.12.046

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Analyses of molecular subtypes and their association to mechanisms of radioresistance in patients with HPV-negative HNSCC treated by postoperative radiochemotherapy

ShivaprasadPatilaij1BouchraTawkfuvwx1MarianneGrossermFabianLohausaiklVolkerGudziolnoMaxKemperlnAlexanderNowaklpDominikHaimlpIngeTinhoferbqVolkerBudachbqMajaGuberinacrMartinStuschkecrPanagiotisBalermpasdsClausRödeldsHenningSchäferetAnca-LigiaGrosuetAmirAbdollahifuvwxJürgenDebusfuvwy…AnnettLingeaikl2

doi : 10.1016/j.radonc.2021.12.049

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Comparison and quantification of different concurrent chemotherapy regimens with radiotherapy in locally advanced non-small cell lung cancer: Clinical outcomes and theoretical results from an extended LQ and TCP model

XinLeiAiacd1BoQiuacdef1YinZhougSuLibcdQiWenLiacdefJianHuanhJiBinLibcdNanHuacdNaiBinChenacdFangJieLiuacdDaQuanWangacdChuChuacdBinWangacdLiChenacdHaiHangJiangiShiYuHuangjXiaoYanHuangacdNanBikHuiLiuacdef

doi : 10.1016/j.radonc.2021.11.033

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ProCaLung – Peer review in stage III, mediastinal node-positive, non-small-cell lung cancer: How to benchmark clinical practice of nodal target volume definition and delineation in Belgium

FlorianCharlieraThomasDescampsaYolandeLievensbXavierGeetscVincentRemouchampsdMaartenLambrechteLuigiMorettia

doi : 10.1016/j.radonc.2021.11.034

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Longitudinal patient-reported outcomes and survival among early-stage non-small cell lung cancer patients receiving stereotactic body radiotherapy

KeaTurnera1Naomi C.Brownsteinb1ZacharyThompsonbIssamEl NaqacYiLuocHeather S.L.JimaDana E.RollisondRachelHowardeDesmondZengfStephen A.RosenbergghBradfordPerezghAndreasSaltoshLaura B.OswaldaBrian D.GonzalezaJessica Y.IslamdAmir AlishahiTabrizaWenbinZhangiThomas J.Dillinggh

doi : 10.1016/j.radonc.2021.12.021

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Pre-treatment immune status predicts disease control in NSCLCs treated with chemoradiation and durvalumab

MariaThoraAnnemarie F.ShepherdbIsabelPreeshagulcMichaelOffincDaphna Y.GelblumbAbraham J.WubAdityaApteaCharles B.SimoneIIbMatthew D.HellmanncAndreasRimnerbJamie E.ChaftcDaniel R.GomezbJoseph O.DeasyaNarekShaverdianb

doi : 10.1016/j.radonc.2021.12.016

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On the interplay between dosiomics and genomics in radiation-induced lymphopenia of lung cancer patients

SerenaMontiaTingXubZhongxingLiaobRadheMohancLauraCellaaGiuseppePalmaad

doi : 10.1016/j.radonc.2021.12.038

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Contouring cardiac substructures on average intensity projection 4D-CT for lung cancer radiotherapy: A proposal of a heart valve contouring atlas

JoannaSochaabAnnaRygielskacBeataUziębło-ŻyczkowskadJustynaChałubińska-FendleraAgnieszkaJurekdMałgorzataMaciorowskadMartaMielniczukdPawełPawłowskiaDobromiraTyc-SzczepaniakaPawełKrzesińskidLucynaKepkaa

doi : 10.1016/j.radonc.2021.12.041

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Variability of gross tumour volume delineation: MRI and CT based tumour and lymph node delineation for lung radiotherapy

ShivaniKumarabcLoisHollowayabcdefMiriamBoxeragMei LingYapabchiPhillipChlapabcDanielMosesjkShaliniVinodabc

doi : 10.1016/j.radonc.2021.11.036

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Germline variants disrupting microRNAs predict long-term genitourinary toxicity after prostate cancer radiation

Amar U.KishanabNicholasMarcocMelanie-BirteSchulz-JaavalldMichael L.SteinbergaPhuoc T.TraneJesus E.JuarezaAudreyDangaDonatelloTelescacWolfgang A.LillebydJoanne B.Weidhaasa

doi : 10.1016/j.radonc.2021.12.040

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Online adaptive radiotherapy potentially reduces toxicity for high-risk prostate cancer treatment

Rasmus LübeckChristiansenabLarsDysagercChristian RønnHansenabHenrik RobenhagenJensenbTineSchytteacChristina JunkerNyborgcAnders SmedegaardBertelsenbSøren NielsenAgergaardbFaisalMahmoodabSteinbjørnHansencOlfredHansenacCarstenBrinkabUffeBernchouab

doi : 10.1016/j.radonc.2021.12.013

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LITE SABR M1: Planning design and dosimetric endpoints for a phase I trial of lattice SBRT

James A.KavanaughMatthew B.SprakerSaiDurisetiFrancoBasarabescuAlexPriceMurtyGodduNelsKnutsonMichaelPrusatorCliffordRobinsonThomasMazur

doi : 10.1016/j.radonc.2021.12.003

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Technical feasibility and clinical evaluation of 4D-MRI guided liver SBRT on the MR-linac

T.N.van de Lindt1M.E.Nowee1T.JanssenC.SchneiderP.RemeijerV.W.J.van PeltA.BetgenE.P.M.JansenJ.J.Sonke

doi : 10.1016/j.radonc.2022.01.009

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Distinct lipid profiles of radiation-induced carotid plaques from atherosclerotic carotid plaques revealed by UPLC-QTOF-MS and DESI–MSI

WeiLiabi1TaoWanga1XiaoZhanga1JungeZhucXu-YingLicFangdaPengdJingDaidJiyueWangbLiyongZhangbYabingWangaXianyangChenefTengXueegChunguangDingdChaodongWangchLiqunJiaoaij

doi : 10.1016/j.radonc.2021.12.006

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In vivo validation and tissue sparing factor for acute damage of pencil beam scanning proton FLASH

BritaSingers SørensenabMateuszKrzysztof SitarzaChristinaAnkjærgaardcJacobJohansenaClaus EAndersencEleniKanoutaaCathrineOvergaardbCaiGrauaPerPoulsenad

doi : 10.1016/j.radonc.2021.12.022

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Platelet glycoprotein Ibα provides radiation protection

AdamCorkenaSanchita P.GhoshcRuofeiDudMarjanBoermabJerryWareaRupakPathakb

doi : 10.1016/j.radonc.2021.12.030

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Deep learning radiomics model related with genomics phenotypes for lymph node metastasis prediction in colorectal cancer

JiaojiaoZhaoa1HanWangb1YinZhangc1RuiWanga1QinLiuaJieLiaXueLiaHanyuHuangdJieZhangaZhaopingZengaJunZhangeZhangYibFanxinZenga

doi : 10.1016/j.radonc.2021.12.031

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Deep learning-based GTV contouring modeling inter- and intra- observer variability in sarcomas

ThibaultMarinac1YueZhuoac1Rita MariaLahoudacFeiTianacXiaoyueMaacFangxuXingacMaryamMoteabbedabcXiaofengLiuacKiraGroggacNadyaShusharinabcJonghyeWooacRuthLimacChaoMaacYen-Lin E.ChenabcGeorgesEl Fakhriac

doi : 10.1016/j.radonc.2021.09.034

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Landscape of mortality during and within thirty days after non-palliative radiotherapy across eleven major cancer types

MichaelXiangaAnn C.RaldowaErqi L.PollombMichael L.SteinbergaAmar U.Kishana

doi : 10.1016/j.radonc.2022.01.008

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Trials and tribulations of bone marrow sparing radiotherapy for cervical cancer. Re: Zhou et al. Radiother Oncol. 2021;165:103–118

Loren K.Mell

doi : 10.1016/j.radonc.2021.11.025

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Could high-dose-rate monotherapy survive beyond stereotactic ablative radiotherapy era for clinically localized prostate cancer?

HideyaYamazakiaGenSuzukiaNorihiroAibeaKojiMasuiaKenYoshidabSatoakiNakamurab

doi : 10.1016/j.radonc.2021.12.015

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Comments on “Whole lung irradiation as a novel treatment for COVID-19: Interim results of an ongoing phase 2 trial in India�

HamidGhaznavia1Joseph J.Bevelacquab1S.A.R.MortazavicS.M.J.MortazavidJames S.Welshef

doi : 10.1016/j.radonc.2021.12.002

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Response to comments on “Whole lung irradiation as a novel treatment for COVID-19: Interim results of an ongoing phase 2 trial in India�

GovindarajGanesanaSasipriyaPonniahaVivekSundarambPraveen KumarMarimuthuaVenkatramanPitchaikannuaManigandanChandrasekaranaJanakiramanThangarasucGunasekaranKannupaiyanaPrabhuRamamoorthyaBrindhaThangarajaRaguram ShreeVaishnavia

doi : 10.1016/j.radonc.2021.12.001

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In regard to MacKay et al: FLASH radiotherapy: Considerations for multibeam and hypofractionation dose delivery

Patriciavan MarlenMaxDaheleBen J.SlotmanWilko F.A.R.Verbakel

doi : 10.1016/j.radonc.2021.12.026

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In regard to Van Marlen: FLASH radiotherapy: Considerations for multibeam and hypofractionation dose delivery

RanaldMackayaNeilBurnetbMatthewLoweacBethanyRothwellcNormanKirkbycKarenKirkbycJolyonHendrya

doi : 10.1016/j.radonc.2021.12.025

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