دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه
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Slow Wave(s) of Enthusiasm: Electrogastrography as an Electrodiagnostic Tool in Clinical Gastroenterology
David J. LevinthalÂ
Equal Pay for Equal Screening: Impact of Patient and Provider Gender on Reimbursement for Screening Colonoscopy
Zoe Post &Joshua MelsonÂ
Monitoring for Ascites in Cirrhosis Using Patient-Generated Health Data: No Longer a Remote Possibility
Marina SerperÂ
BAD on the Runs: Improved Diagnosis of Idiopathic Bile Acid Diarrhea
Michael CamilleriÂ
Staying in HRAM’s Way: Tweaking the London Classification for Disorders of Anorectal Function
Massimo Bellini & Giuseppe Chiarioni
Current Therapy: Defecation Disorders in the Era of Neuromodulation
Lusine AmbartsumyanÂ
Value of a Growth Mindset: Improving Endoscopy Coaching and Mentoring
Andrew Ming-Liang Ong & Keith Siau
Teaching Colonoscopy: Scope of Practice or Practice of Scope?
Joseph C. YarzeÂ
Hypertriglyceridemia Acute Pancreatitis: Animal Experiment Research
Lu Wang, Ting Xu, Ruifeng Wang, Xiaobing Wang & Dong Wu
Abnormalities on Electrogastrography in Nausea and Vomiting Syndromes: A Systematic Review, Meta-Analysis, and Comparison to Other Gastric Disorders
Daniel A. Carson, Sameer Bhat, Tommy C. L. Hayes, Armen A. Gharibans, Christopher N. Andrews, Gregory O’Grady & Chris Varghese
Mesenteric Cyst with GI Symptoms: A Fluid Approach to Treatment—Case Report and Literature Review
Federica Gagliardi, Augusto Lauro, Domenico Tripodi, Maria Ida Amabile, Piergaspare Palumbo, Filippo Maria Di Matteo, Giorgio Palazzini, Flavio Forte,
From ICI to ICU: Ipilimumab and Nivolumab-Induced Immune Checkpoint Inhibitor Colitis
Wendy Zhou, Joseph Frye, Camille Soroudi, George Triadafilopoulos & Rani Berry
Rare and Well Done: Endoscopic Control of Colonic Hemorrhage in Severe Ulcerative Colitis
Shintaro Akiyama, Nathaniel A. Cohen, Joshua M. Steinberg, Scott Friedberg & Russell D. Cohen
Gender Differences in Colonoscopy: Implications for Clinical Practice and Female Gastroenterologists
Karin L. Andersson, Jasmine B. Ha, Diane R. Abraczinskas, Emily J. Campbell & James M. Richter
Inappropriateness of Proton Pump Inhibitors After Hospital Discharge Is Associated with Thirty-Day Hospital Readmission
John W. Blackett, Ling Chen, Jianhua Li, Jason D. Wright & Daniel E. Freedberg
Pros and Cons of Performing Early Endoscopy in Geriatric Patients Admitted with Non-variceal Upper Gastrointestinal Bleeding: Analysis of the US National Inpatient Database
Mohammed El-Dallal, Trent J. Walradt, Daniel J. Stein, Usah Khrucharoen & Joseph D. Feuerstein
Thirty-Day Readmission After Bariatric Surgery: Causes, Effects on Outcomes, and Predictors
Pedro Palacios Argueta, Miguel Salazar, John J. Vargo, Prabhleen Chahal, John J. Rodriguez, C. Roberto Simons-Linares & Christopher C. Thompson
Using Wearable Biosensors to Predict Length of Stay for Patients with IBD After Bowel Surgery
Yangtian Yi, Philip H. Sossenheimer, Amarachi I. Erondu, Kinga B. Skowron, Victoria Rai, Jorie M. Singer, Katia El Jurdi, Neil H. Hyman & David T. Rub
doi : 10.1007/s10620-021-06910-w
It remains unknown whether ambulation or sleep predicts postoperative length of stay for patients with IBD. We aim to identify the utility of wearable biosensors in predicting postoperative length of stay for patients with IBD.
A Telemonitoring Intervention for Cirrhotic Ascites Management Is Cost-Saving
Patricia P. Bloom, Martin Ventoso, Elliot Tapper, Jasmine Ha & James M. Richter
doi : 10.1007/s10620-021-07013-2
Patients with cirrhosis and ascites experience frequent hospital admissions, leading to poor quality of life and high healthcare costs. Monitoring weight is a component of ascites care and telemonitoring may improve outcomes and costs.
Galectin-4 as a Novel Biomarker of Neonatal Intestinal Injury
Jennifer B. Fundora, Jie Zhu, Lisa R. Yanek, Mitzi Go, Fauzia Shakeel, Sandra S. Brooks, Jun Yang, David J. Hackam, Allen D. Everett & Darla R. Shores
doi : 10.1007/s10620-021-06929-z
Neonates are at risk of gastrointestinal emergencies including necrotizing enterocolitis (NEC) and spontaneous intestinal perforation (SIP). Identifying biomarkers to aid in diagnosis is imperative. We hypothesized that circulating intestinal-specific protein concentrations would distinguish infants with intestinal injury from controls.
Downregulation of Serum and Distal Ileum Fibroblast Growth Factor19 in Bile Acid Diarrhoea Patients
Chunxia Chang, Jingjing Jiang, Rui Sun, Shenggen Wang & Hong Chen
doi : 10.1007/s10620-021-07042-x
Bile acid diarrhoea or BAD is a common but little recognised cause of chronic diarrhoea. Few of these patients in China have been diagnosed due to a lack of diagnostic options.
Proteasome Subunit Alpha Type 7 Promotes Proliferation and Metastasis of Gastric Cancer Through MAPK Signaling Pathway
Shujing Xia, Lei Ji, Lizhong Tang, Lili Zhang, Xiumei Zhang, Qi Tang, Zhenqing Feng & Lungen Lu
doi : 10.1007/s10620-021-06903-9
Proteasome subunit alpha type 7 (PSMA7) shows a carcinogenic effect on various human malignancies, but its role and regulatory mechanism in gastric carcinoma (GC) remain unclear.
Circ_0023984 Facilitates Esophageal Squamous Cell Carcinoma Progression by Regulating miR-433-3p/REV3L Axis
Ting Li &Suping LiÂ
doi : 10.1007/s10620-021-06916-4
It has been revealed that circular RNAs (circRNAs) play an important role in regulating the malignant phenotype of tumor cells, thus involving in the progression of malignancies. However, the role of circ_0023984 in esophageal squamous cell carcinoma (ESCC) remains largely unclear.
Reciprocal Expression of Differentiated Embryonic Chondrocyte Expressed Genes Result in Functional Antagonism in Gastric Cancer
Binbin Li, Yan Chu, Bing Yan, Xiaoli Ma, Duanrui Liu, Shanglin Wang, Yunshan Wang & Yanfei Jia
doi : 10.1007/s10620-021-06921-7
Differentiated embryonic chondrocyte expressed genes (DECs) are critical regulators of cellular proliferation and differentiation. However, DEC1 and DEC2 as family member have opposite or identical roles in tumor, acting as an “accelerator� or a “brake� in progression.
OPA Interacting Protein 5 Antisense RNA 1 Expedites Cell Migration and Invasion Through FOXM1/ Wnt/β-Catenin Pathway in Pancreatic Cancer
Chengjian Shi, Hang Zhang, Min Wang, Rui Tian, Xu Li, Yechen Feng, Feng Peng & Renyi Qin
doi : 10.1007/s10620-021-06919-1
Pancreatic cancer (PC) is a digestive tract malignancy with poor prognosis. Long noncoding RNA (lncRNA) OPA interacting protein 5 antisense RNA 1 (OIP5-AS1) was regarded to be correlated with human malignancy, working as tumor suppressor or promoter on the basis of tumor types. However, the function of OIP5-AS1 in PC remained unclear.
LncRNA SNHG7 Promotes the HCC Progression Through miR-122-5p/FOXK2 Axis
Zhengbin Zhao, Jing Gao & Shuangsheng Huang
doi : 10.1007/s10620-021-06918-2
Hepatocellular carcinoma (HCC) is a malignant tumor with high mortality and severe complication in China. Numerous studies have shown that long noncoding RNAs (lncRNAs) are involved in the regulation of various processes in cancer cells. Our research aimed to investigate the underlying mechanism of the lncRNA small nucleolar RNA host gene 7 (SNHG7) in HCC development. The expression of SNHG7, microRNA-122-5p (miR-122-5p), and Forkhead box K2 (FOXK2) was assessed via quantitative real-time polymerase chain reaction. 3-(4,5) -dimethylthiahiazo (-z-y1)-3,5-di-phenytetrazoliumromide (MTT) and transwell assays were performed to measure cell viability, migration, and invasion, respectively. The relative protein levels were detected by Western blot. The relationships between miR-122-5p and SNHG7 or FOXK2 were predicted by online software and then confirmed by dual-luciferase reporter assay. Animal experiments were conducted to clarify the effects of SNHG7 on proliferation in vivo. To begin with, SNHG7 was upregulated, while miR-122-5p was downregulated in HCC tissues and cells. Downregulation of SNHG7 inhibited cell growth and metastasis. Interestingly, SNHG7 could abolish the effects of miR-122-5p on HCC cells. Furthermore, miR-122-5p targeted FOXK2 and miR-122-5p recovered the effects of FOXK2 downregulation on cell growth and metastasis in HCC cells. Besides, SNHG7 facilitated HCC tumor growth in vivo through the miR-122-5p/FOXK2 axis. The lncRNA SNHG7 boosted the development of HCC by regulating FOXK2 through sponging miR-122-5p.
LncRNA SNHG14 Sponges miR-206 to Affect Proliferation, Apoptosis, and Metastasis of Hepatocellular Carcinoma Cells by Regulating SOX9
Rui-Xin Lin, Guo-Feng Zhan, Jia-Cheng Wu, He Fang & Shu-Li Yang
doi : 10.1007/s10620-021-06920-8
To explore how lncRNA SNHG14 modulates the biological features of hepatocellular carcinoma (HCC) cells by regulating SOX9 via mediating miR-206.
A Novel Flocked Swab Protocol Proves to Be an Effective Method for Culturing Elevator-Containing Endoscopes
Jennifer Y. Lui, Christopher G. Chapman, Irving Waxman & Uzma D. Siddiqui
doi : 10.1007/s10620-021-06930-6
The challenging disinfection process for the elevator mechanism on duodenoscopes and linear echoendoscopes has been identified as a source of clinically significant bacterial transmission. Despite increased awareness, there continues to be a lack of definitive guidelines for bacterial culturing protocols for elevator-containing endoscopes.
Safety and Efficacy of Thrombin for Bleeding Gastric Varices: A Systematic Review and Meta-Analysis
Abhishek Bhurwal, Michael Makar, Anish Patel, Hemant Mutneja, Akshay Goel, Michal Bartel, Haroon Shahid, Mihajlo Gjeorgjievski, Vinod Rustgi & Avik Sa
doi : 10.1007/s10620-021-06915-5
The optimal therapy for bleeding-related gastric varices is still a controversial topic. There is a paucity of literature that comprehensively summarizes the available literature regarding safety and efficacy of thrombin in bleeding gastric varices.
Redundancy in the International Anorectal Physiology Working Group Manometry Protocol: A Diagnostic Accuracy Study in Fecal Incontinence
Daphne Ang, Paul Vollebregt, Emma V. Carrington, Charles H. Knowles & S. Mark Scott
doi : 10.1007/s10620-021-06994-4
Anorectal manometry (ARM) is essential for identifying sphincteric dysfunction. The International Anorectal Physiology Working Group (IAPWG) protocol and London Classification provide a standardized format for performing and interpreting ARM. However, there is scant evidence to support timing and number of constituent maneuvers.
Feasibility Study of Partial Submucosal Injection Technique Combining Underwater EMR for Superficial Duodenal Epithelial Tumors
Yusaku Takatori, Motohiko Kato, Teppei Masunaga, Yoko Kubosawa, Mari Mizutani, Yoshiyuki Kiguchi, Noriko Matsuura, Atsushi Nakayama, Tadateru Maehata
doi : 10.1007/s10620-021-06925-3
Endoscopic mucosal resection (EMR) and Underwater EMR have been reported as effective endoscopic treatment for superficial duodenal tumor (SDET). However, a notable problem of EMR for SDET is technical difficulty for the lesion with non-lifting sign, and it of UEMR is that en bloc resection rate is relatively low. Therefore, we performed partial submucosal injection combining UEMR (PI-UEMR). The aim of this study is to evaluate feasibility and safety of this technique for duodenal tumor.
Systematic Review with Meta-Analysis: Fecal Microbiota Transplantation for Severe or Fulminant Clostridioides difficile
Emily N. Tixier, Elijah Verheyen, Yuying Luo, Lauren Tal Grinspan, Charles H. Du, Ryan C. Ungaro, Samantha Walsh & Ari M. Grinspan
doi : 10.1007/s10620-021-06908-4
Severe and fulminant Clostridioides difficile infection (CDI) is associated with significant morbidity and mortality. While fecal microbiota transplantation (FMT) has proved to be a highly effective treatment for recurrent CDI, its efficacy in severe or fulminant CDI remains uncertain.
Comparative Efficacy of Transcutaneous Functional Electrical Stimulation With or Without Biofeedback Therapy on Functional Non-retentive Fecal Incontinence in Children: A Randomized Clinical Trial
Seyedeh-Sanam Ladi-Seyedian, Lida Sharifi-Rad, Hosein Alimadadi, Behnam Nabavizadeh, Navid Manouchehri, Bahar Allahverdi, Farzaneh Motamed & Gholam-Ho
doi : 10.1007/s10620-021-07012-3
We compared the effects of transcutaneous functional electrical stimulation (TFES) and biofeedback therapy with TFES alone in a cohort of children with functional non-retentive fecal incontinence (FNRFI).
Poor Concordance Between Clinical Activity and Endoscopic Severity in Pediatric Crohn’s Disease: Before and After Induction Therapy
Yu Yu, Hong Zhao, Youyou Luo, Jingan Lou, Jie Chen & Youhong Fang
doi : 10.1007/s10620-021-06917-3
Endoscopic assessments of disease activity are important to diagnose and evaluate treatment responses in patients with Crohn’s disease (CD). However, the invasiveness of endoscopy limits the application of this technique in routine examination. Thus, interest has been increasing in identifying noninvasive surrogate markers to predict endoscopic CD activity.
Predictors of Response to Vedolizumab in Patients with Ulcerative Colitis: Results from the Greek VEDO-IBD Cohort
Giorgos Bamias, Georgios Kokkotis, Michalis Gizis, Christina Kapizioni, Konstantinos Karmiris, Evgenia Koureta, Nikolaos Kyriakos, Georgios Leonidakis
doi : 10.1007/s10620-021-06907-5
Optimization of treatment with biologics is currently an unmet need for patients with ulcerative colitis (UC). Real-world studies provide neutral estimates of drug efficacy and safety within unselected patient populations and allow for the recognition of specific characteristics that affect response to therapy.
Effectiveness and Safety of Ustekinumab in Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis
Sailish Honap, Susanna Meade, Hajir Ibraheim, Peter M. Irving, Michael P. Jones & Mark A. Samaan
doi : 10.1007/s10620-021-06932-4
Ustekinumab, an interleukin-12 and interleukin-23 antagonist, is licensed for the treatment of Crohn’s disease (CD) and ulcerative colitis (UC) after the phase III trial programs demonstrated efficacy over placebo. However, these findings may not be directly transferable to the real-world due to the stringent inclusion criteria of clinical trials.
Receipt of Serial Endoscopy Procedures Prior to Esophageal Adenocarcinoma Diagnosis Is Associated with Better Survival
Linda C. Cummings, Tzuyung Doug Kou, Amitabh Chak, Mark D. Schluchter, Seunghee Margevicius & Gregory S. Cooper
doi : 10.1007/s10620-021-06927-1
The poor prognosis of esophageal adenocarcinoma (EAC) has focused efforts on early detection by serial endoscopic surveillance of Barrett’s esophagus (BE). Previously, we reported that receipt of endoscopy before EAC diagnosis was associated with improved survival.
Early-Onset Colorectal Cancer Is Associated with a Lower Risk of Metachronous Advanced Neoplasia than Traditional-Onset Colorectal Cancer
Frank W. Chen, Liu Yang, Vivy T. Cusumano, Michelle C. Chong, Jonathan K. Lin, Diana Partida & Folasade P. May
doi : 10.1007/s10620-021-06902-w
Colorectal cancer (CRC) incidence in the USA has increased in adults under age 50. Current CRC surveillance guidelines do not consider age at diagnosis, and there are limited data available on outcomes from surveillance colonoscopies in early-onset CRC (EO-CRC) to guide recommendations on surveillance intervals.
Efficacy of Contrast-Enhanced Harmonic Endoscopic Ultrasound for Pancreatic Solid Tumors with a Combination of Qualitative and Quantitative Analyses: A Prospective Pilot Study
Yuhei Iwasa, Takuji Iwashita, Hironao Ichikawa, Naoki Mita, Shinya Uemura, Kensaku Yoshida, Keisuke Iwata, Tsuyoshi Mukai, Ichiro Yasuda & Masahito Sh
doi : 10.1007/s10620-021-06931-5
Image evaluation of contrast-enhanced harmonic endoscopic ultrasound (CEH-EUS) and additional time-intensity curve (TIC) analysis enable qualitative and quantitative analyses of pancreatic tumor based on real-time perfusion imaging.
Pancreas Cancer Incidence and Pancreas Cancer-Associated Mortality Are Low in National Cohort of 7211 Pancreas Cyst Patients
Gobind S. Anand, Fady Youssef, Lin Liu, Ranier Bustamante, Ashley Earles, Santhi Swaroop Vege, Thomas Savides, Syed Abbas Fehmi, Wilson T. Kwong & Sam
doi : 10.1007/s10620-021-06923-5
Pancreatic cancer incidence and mortality among patients with pancreas cysts are unclear. The aims of this study are to evaluate incidence of pancreatic cancer and cause-specific mortality among patients with pancreatic cysts using a large national cohort over a long follow-up period.
Long Slimmer Metal Stent Is Feasible and Effective for Endoscopic Dual Stent-by-Stent Placement in Malignant Hilar Biliary Stricture
Dao-jian Gao, Ling Xing, Xin Ye, Tian-tian Wang, Jun Wu, Ming-xing Xia & Bing Hu
doi : 10.1007/s10620-021-06906-6
Bilateral endoscopic biliary stenting remains technically challenging, which limits its wider clinical application.
An Unusual Cause of Diarrhea
Andrew Joelson, Benjamin Lebwohl, Stuart Bentley-Hibbert, Steven Lee-Kong & Oscar Lebwohl
