Ear and Hearing




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The Use of Person-centered Language in Medical Research Articles Focusing on Hearing Loss or Deafness.

Nicks, Savannah 1; Johnson, Austin L. 1; Traxler, Brett 1; Bush, Matthew L. 2; Brame, Lacy 3; Hamilton, Tom 3; Hartwell, Micah 1

doi : 10.1097/AUD.0000000000001168

Volume 43(3) pgs. 703-1087 May/June 2022

Hearing loss represents one of the most common disabilities worldwide. Despite its prevalence, there is a degree of stigmatization within the public's perception of, or attitude toward, individuals diagnosed with hearing loss or deafness. This stigmatization is propagated by the way hearing loss is referenced, especially in writing. Although the medical community is familiar with hearing loss, medical research is not consistently compliant with nonstigmatizing terminology, like person-centered language (PCL). This study aims to quantify the use of PCL in medical research related to hearing loss

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A Systematic Review on the Association Between Vestibular Dysfunction and Balance Performance in Children With Hearing Loss.

Singh, Anisha 1,2; Heet, Hannah 3; Guggenheim, Dana S. 4; Lim, Margaret 4; Garg, Bhavika 4; Bao, Matthew 4; Smith, Sherri L. 3,5,6; Garrison, Doug 3; Raynor, Eileen M. 3; Lee, Janet W. 3; Wrigley, Jordan 7; Riska, Kristal M. 3,5

doi : 10.1097/AUD.0000000000001131

pg. 712-721

The objective of this study was to understand the functional impact of vestibular dysfunction on balance control in children with hearing loss. The vestibular system is an important contributor to maintaining balance. In adults, vestibular dysfunction is known to lead to unsteadiness and falls. Considerably less is known about the effects of vestibular dysfunction in children with hearing loss.

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Early Life Influences on Hearing in Adulthood: a Systematic Review and Two-Step Individual Patient Data Meta-Analysis.

Dawes, Piers 1,2; Newall, John 3; Graham, Petra L. 4; Osmond, Clive 5; von Bonsdorff, Mikaela B. 6,7; Gunnar Eriksson, Johan 7,8,9

doi : 10.1097/AUD.0000000000001163

pg. 722-732

Adverse prenatal and early childhood development may increase susceptibility of hearing loss in adulthood. The objective was to assess whether indices of early development are associated with adult-onset hearing loss in adults >=18 years. Design: In a systematic review and meta-analysis, four electronic databases were searched for studies reporting associations between indices of early development (birth weight and adult height) and adult-onset hearing loss in adults >=18 years. We screened studies, extracted data, and assessed risk of bias. Authors were contacted to provide adjusted odds ratios from a logistic regression model for relationships between birth weight/adult height and normal/impaired hearing enabling a two-step individual patient data random-effects meta-analysis to be carried out. The study is registered with PROSPERO, CRD42020152214. Results: Four studies of birth weight and seven of adult height were identified.

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Identifying the Factors that Affect Consistent Hearing Aid Use in Young Children With Early Identified Hearing Loss: A Scoping Review.

Nailand, Lisa 1,2; Munro, Natalie 1; Purcell, Alison 1

doi : 10.1097/AUD.0000000000001139

pg. 733-740

This study is a scoping review examining factors that affect consistent hearing aid use in young children with early identified hearing loss (HL). Design: Online databases were used to identify journal articles published between 2009 and 2019, yielding over 1800 citations. The citations were uploaded into an online software product called Covidence that enables scoping/systematic review management. After duplicates were removed, 857 articles were screened by abstract and title name, 93 of which were put through for full-text screening. Twenty-five articles met predetermined inclusion and exclusion criteria.

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Cogmed Training Does Not Generalize to Real-World Benefits for Adult Hearing Aid Users: Results of a Blinded, Active-Controlled Randomized Trial.

Henshaw, Helen 1,2; Heinrich, Antje 3; Tittle, Ashana 1,2; Ferguson, Melanie 1,4,5,6

doi : 10.1097/AUD.0000000000001096

pg. 741-763

Performance on working memory tasks is positively associated with speech-in-noise perception performance, particularly where auditory inputs are degraded. It is suggested that interventions designed to improve working memory capacity may improve domain-general working memory performance for people with hearing loss, to benefit their real-world listening. We examined whether a 5-week training program that primarily targets the storage component of working memory (Cogmed RM, adaptive) could improve cognition, speech-in-noise perception and self-reported hearing in a randomized controlled trial of adult hearing aid users with mild to moderate hearing loss, compared with an active control (Cogmed RM, nonadaptive) group of adults from the same population.

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Distortion of Spectral Ripples Through Cochlear Implants Has Major Implications for Interpreting Performance Scores.

Winn, Matthew B. 1; O'Brien, Gabrielle 2

doi : 10.1097/AUD.0000000000001162

pg. 764-772

AB The spectral ripple discrimination task is a psychophysical measure that has been found to correlate with speech recognition in listeners with cochlear implants (CIs). However, at ripple densities above a critical value (around 2 RPO, but device-specific), the sparse spectral sampling of CI processors results in stimulus distortions resulting in aliasing and unintended changes in modulation depth. As a result, spectral ripple thresholds above a certain number are not ordered monotonically along the RPO dimension and thus cannot be considered better or worse spectral resolution than each other, thus undermining correlation measurements.

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Understanding Self-reported Hearing Disability in Adults With Normal Hearing.

Kamerer, Aryn M.; Harris, Sara E.; Kopun, Judy G.; Neely, Stephen T.; Rasetshwane, Daniel M.

doi : 10.1097/AUD.0000000000001161

pg. 773-784

Despite a diagnosis of normal hearing, many people experience hearing disability (HD) in their everyday lives. This study assessed the ability of a number of demographic and auditory variables to explain and predict self-reported HD in people regarded as audiologically healthy via audiometric thresholds. Design: One-hundred eleven adults (ages 19 to 74) with clinically normal hearing (i.e., audiometric thresholds <=25 dB HL at all octave and interoctave frequencies between 0.25 and 8 kHz and bilaterally symmetric hearing) were asked to complete the 12-item version of the Speech, Spatial, and Qualities of Hearing Scale (SSQ12) as a measure of self-reported HD. Patient history and a number of standard and expanded measures of hearing were assessed in a multivariate regression analysis to predict SSQ12 score.

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Descriptions of Hearing Aids Influence the Experience of Listening to Hearing Aids.

Rakita, Lori 1; Goy, Huiwen 2; Singh, Gurjit 2,3,4

doi : 10.1097/AUD.0000000000001130

pg. 785-793

Experiences can be strongly influenced by expectations. In hearing healthcare, previous studies have shown that descriptions of hearing aids or contextual factors during the hearing aid fitting process can change subjective and even objective outcomes with hearing aids via the placebo effect. Personality factors have also been shown to affect susceptibility to placebo effects. The purposes of the present study were to (a) investigate the effects of communicating narratives designed to foster positive, negative, or neutral expectations about hearing aids on short-term patient outcomes, and (b) to determine if the degree to which the narratives affected end-user outcomes could be predicted by personality factors. Design: Nineteen adults between the ages of 54 and 81 (mean age = 68.5, SD = 8.9) had 3 separate research appointments, each exposing them to a different narrative condition: positive, negative, or neutral.

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Ototoxicity After Cisplatin-Based Chemotherapy: Factors Associated With Discrepancies Between Patient-Reported Outcomes and Audiometric Assessments.

Ardeshirrouhanifard, Shirin 1; Fossa, Sophie D. 2; Huddart, Robert 3; Monahan, Patrick O. 1; Fung, Chunkit 4; Song, Yiqing 1; Dolan, M. Eileen 5; Feldman, Darren R. 6; Hamilton, Robert J. 7; Vaughn, David 8; Martin, Neil E. 9; Kollmannsberger, Christian 10; Dinh, Paul 1; Einhorn, Lawrence 1; Frisina, Robert D. 11; Travis, Lois B. 1

doi : 10.1097/AUD.0000000000001172

pg. 794-807

To provide new information on factors associated with discrepancies between patient-reported and audiometrically defined hearing loss (HL) in adult-onset cancer survivors after cisplatin-based chemotherapy (CBCT) and to comprehensively investigate risk factors associated with audiometrically defined HL. Design: A total of 1410 testicular cancer survivors (TCS) >=6 months post-CBCT underwent comprehensive audiometric assessments (0.25 to 12 kHz) and completed questionnaires. HL severity was defined using American Speech-Language-Hearing Association criteria. Multivariable multinomial regression identified factors associated with discrepancies between patient-reported and audiometrically defined HL and multivariable ordinal regression evaluated factors associated with the latter.

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Amplification Self-Adjustment: Controls and Repeatability.

Boothroyd, Arthur; Retana, Jennifer; Mackersie, Carol L.

doi : 10.1097/AUD.0000000000001141

pg. 808-821

This study was a continuation of work on an explore-and-select approach to the self-adjustment of amplification. Goals were to determine (i) the effect of changing the number of adjustment controls from three to two, (ii) the effect of changing the initial adjustment from overall output to high-frequency output, (iii) individual repeatability, (iv) the effect on phoneme recognition of increasing and decreasing overall output relative to the starting and adjusted conditions, and (v) listener reactions to, and opinions of, the self-adjustment procedure.

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Extended High-frequency Hearing Impairment Despite a Normal Audiogram: Relation to Early Aging, Speech-in-noise Perception, Cochlear Function, and Routine Earphone Use.

Mishra, Srikanta K. 1; Saxena, Udit 2; Rodrigo, Hansapani 3

doi : 10.1097/AUD.0000000000001140

pg. 822-835

Humans can hear up to 20 kHz. Emerging evidence suggests that hearing in the extended high frequencies (EHFs; >8 kHz) contributes to speech perception in noise. The objective of the present study was to describe the features of EHF hearing impairment in young adults with normal standard audiograms (0.25-8 kHz). Specifically, the study goals were to: (1) characterize the EHF hearing impairment and identify potential risk factors; (2) elucidate the age-related changes in EHF hearing; (3) determine the effect of EHF hearing impairment on speech-in-noise recognition; and (4) examine the extent to which EHF hearing impairment influences cochlear functioning in the standard frequencies.

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Reduced Semantic Context and Signal-to-Noise Ratio Increase Listening Effort As Measured Using Functional Near-Infrared Spectroscopy.

Rovetti, Joseph; Goy, Huiwen; Zara, Michael; Russo, Frank A.

doi : 10.1097/AUD.0000000000001137

pg. 836-848

Understanding speech-in-noise can be highly effortful. Decreasing the signal-to-noise ratio (SNR) of speech increases listening effort, but it is relatively unclear if decreasing the level of semantic context does as well. The current study used functional near-infrared spectroscopy to evaluate two primary hypotheses: (1) listening effort (operationalized as oxygenation of the left lateral PFC) increases as the SNR decreases and (2) listening effort increases as context decreases.

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Effect of Noise Reduction on Cortical Speech-in-Noise Processing and Its Variance due to Individual Noise Tolerance.

Kim, Subong 1; Wu, Yu-Hsiang 2; Bharadwaj, Hari M. 1,3; Choi, Inyong 2,4

doi : 10.1097/AUD.0000000000001144

pg. 849-861

Despite the widespread use of noise reduction (NR) in modern digital hearing aids, our neurophysiological understanding of how NR affects speech-in-noise perception and why its effect is variable is limited. The current study aimed to (1) characterize the effect of NR on the neural processing of target speech and (2) seek neural determinants of individual differences in the NR effect on speech-in-noise performance, hypothesizing that an individual's own capability to inhibit background noise would inversely predict NR benefits in speech-in-noise perception. Design: Thirty-six adult listeners with normal hearing participated in the study. Behavioral and electroencephalographic responses were simultaneously obtained during a speech-in-noise task in which natural monosyllabic words were presented at three different signal-to-noise ratios, each with NR off and on.

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Cochlear Implant Compression Optimization for Musical Sound Quality in MED-EL Users.

Gilbert, Melanie L. 1; Deroche, Mickael L. D. 2; Jiradejvong, Patpong 1; Chan Barrett, Karen 1; Limb, Charles J. 1

doi : 10.1097/AUD.0000000000001145

pg. 862-873

Variations in loudness are a fundamental component of the music listening experience. Cochlear implant (CI) processing, including amplitude compression, and a degraded auditory system may further degrade these loudness cues and decrease the enjoyment of music listening. This study aimed to identify optimal CI sound processor compression settings to improve music sound quality for CI users.

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Intraoperative Electrocochleography in Subjects Affected by Vestibular Schwannoma and Meniere's Disease: Comparison of Results.

Trecca, Eleonora M. C. 1,2; Adunka, Oliver F. 3; Hiss, Meghan M. 3; Mattingly, Jameson K. 3; Moberly, Aaron C. 3; Dodson, Edward E. 3; Cassano, Michele 2; Prevedello, Daniel M. 4; Riggs, William J. 3

doi : 10.1097/AUD.0000000000001133

pg. 874-882

Histologic reports of temporal bones of ears with vestibular schwannomas (VSs) have indicated findings of endolymphatic hydrops (ELH) in some cases. The main goal of this investigation was to test ears with VSs to determine if they exhibit electrophysiological characteristics similar to those of ears expected to experience ELH. Design: Fifty-three subjects with surgically confirmed VS aged >=18 and with normal middle ear status were included in this study. In addition, a second group of adult subjects (n = 24) undergoing labyrinthectomy (n = 6) or endolymphatic sac decompression and shunt (ELS) placement (n = 18) for poorly controlled vestibular symptoms associated with Meniere's disease (MD) participated in this research. Intraoperative electrocochleography (ECochG) from the round window was performed using tone burst stimuli.

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Vocal Turn-Taking in Families With Children With and Without Hearing Loss.

Kondaurova, Maria V. 1; Zheng, Qi 2; VanDam, Mark 3; Kinney, Kaelin 1

doi : 10.1097/AUD.0000000000001135

pg. 883-898

Vocal turn-taking is an important predictor of language development in children with and without hearing loss. Most studies have examined vocal turn-taking in mother-child dyads without considering the multitalker context in a child's life. The present study investigates the quantity of vocal turns between deaf and hard-of-hearing children and multiple members of their social environment. Design: Participants were 52 families with children who used hearing aids (HA, mean age 26.3 mo) or cochlear implants (CI, mean age 63.2 mo) and 27 families with normal-hearing (NH, mean age 26.6 mo) children. The Language ENvironment Analysis system estimated the number of conversational turns per hour (CTC/hr) between all family members (i.e., adult female, adult male, target child, and other child) during full-day recordings over a period of about 1 year.

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Listening Effort Measured Using a Dual-task Paradigm in Adults With Different Amounts of Noise Exposure.

Degeest, Sofie 1; Kestens, Katrien 1; Keppler, Hannah 1,2

doi : 10.1097/AUD.0000000000001138

pg. 899-912

Excessive noise levels can result in hearing damage and/or hearing-related symptoms, thereby leading to impaired communication and, eventually a decrease in the quality of life. Moreover, in daily practice, subjects often indicate that listening in noisy situations is a challenging and often exhausting experience, even in the absence of a clinically significant hearing loss. Hence, a person's perceived difficulty of the listening situation will also be important to consider. It has been suggested that beyond the peripheral factors, there are some central cognitive correlates of speech understanding that are essential for communication abilities. The aim of the present study was to evaluate the effect of the amount of noise exposure on hearing as measured by pure-tone audiometry and otoacoustic emissions (OAEs) on the one hand and listening effort measured using a dual-task paradigm on the other hand.

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The Importance of Extended High-Frequency Speech Information in the Recognition of Digits, Words, and Sentences in Quiet and Noise.

Polspoel, Sigrid 1; Kramer, Sophia E. 1; van Dijk, Bas 2; Smits, Cas 1

doi : 10.1097/AUD.0000000000001142

pg. 913-920

In pure-tone audiometry, hearing thresholds are typically measured up to 8 kHz. Recent research has shown that extended high-frequency (EHF; frequencies >8 kHz) speech information improves speech recognition. However, it is unclear whether the EHF benefit is present for different types of speech material. This study assesses the added value of EHF information for speech recognition in noise for digit triplets, consonant-vowel-consonant (CVC) words, and sentences; and for speech recognition in quiet for CVC. Design: Twenty-four young adults with normal-hearing thresholds up to 16 kHz performed a listening experiment in quiet and in noise in a within-subject repeated measures design. Stimuli were presented monaurally.

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Smartphone-Connected Hearing Aids Enable and Empower Self-Management of Hearing Loss: A Qualitative Interview Study Underpinned by the Behavior Change Wheel.

Gomez, Rachel 1,2,3; Habib, Alia 1,4,5; Maidment, David W. 1,4,6; Ferguson, Melanie A. 1,7,8

doi : 10.1097/AUD.0000000000001143

pg. 921-932

To identify patient-reported barriers and facilitators to using smartphone-connected hearing aids, using the Behavior Change Wheel (BCW) to understand experiences and how these can be addressed. Design: A single-center, prospective, observational study. Eight hearing aid users (new = 1, existing = 7; mean age = 71.75 years, SD = 5.23, range = 65 to 81 years) were identified through convenience sampling from 44 participants who took part in a 7-week evaluation of smartphone-connected hearing aids controlled by a prototype app.

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The Effect of Hearing Aid Use on the Association Between Hearing Loss and Brain Structure in Older Adults.

de Boer, Tom G. 1; Rigters, Stephanie C. 1; Croll, Pauline H. 1,2,3; Niessen, Wiro J. 3,4; Ikram, M. Arfan 2,3; van der Schroeff, Marc P. 1; Vernooij, Meike W. 2,3; Goedegebure, Andre 1

doi : 10.1097/AUD.0000000000001148

pg. 933-940

Recent studies have shown an association between poorer hearing thresholds and smaller brain tissue volumes in older adults. Several underlying causal mechanisms have been opted, with a sensory deprivation hypothesis as one of the most prominent. If hearing deprivation would lead to less brain volume, hearing aids could be hypothesized to moderate this pathway by restoration of hearing. This study aims to investigate whether such a moderating effect of hearing aids exists.

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Using Narrow Band CE-Chirps to Elicit Cervical Vestibular Evoked Myogenic Potentials.

Mat, Quentin 1,2; Deggouj, Naima 3; Duterme, Jean-Pierre 1; Tainmont, Sophie 1; Lelubre, Christophe 2,4; Manto, Mario 2,5

doi : 10.1097/AUD.0000000000001146

pg. 941-948

To compare the effects of Narrow band CE-Chirps (NB CE-Chirps) and tone bursts (TBs) at 500 Hz and 1000 Hz on the amplitudes and latencies in cervical vestibular evoked myogenic potentials (cVEMPs). Design: Thirty-one healthy adult volunteers of varying ages were tested by air conduction at 95 dB nHL. Recording conditions were randomized for each participant and each modality was tested twice.

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Auditory Brainstem Response Detection Using Machine Learning: A Comparison With Statistical Detection Methods.

McKearney, Richard M.; Bell, Steven L.; Chesnaye, Michael A.; Simpson, David M.

doi : 10.1097/AUD.0000000000001151

pg. 949-960

The primary objective of this study was to train and test machine learning algorithms to be able to detect accurately whether EEG data contains an auditory brainstem response (ABR) or not and recommend suitable machine learning methods. In addition, the performance of the best machine learning algorithm was compared with that of prominent statistical detection methods.

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The Association Between Hearing Loss and Surgical Complications in Older Adults.

Huang, Ryan J. 1; Riska, Kristal M. 1,4; Gordee, Alexander 2; Peskoe, Sarah B. 2; Francis, Howard W. 1; Witsell, David L. 1; Smith, Sherri L. 1,3,4,5

doi : 10.1097/AUD.0000000000001152

pg. 961-971

In this study, we sought to evaluate whether older patients with hearing loss who underwent surgery were at greater risk of postsurgical complications, increased inpatient length-of-stay (LOS), and hospital readmission. Design: This was a retrospective cohort study of patients receiving surgery at a tertiary medical center. Utilizing electronic health record data from two merged datasets, we identified patients 65 years and older, undergoing major surgery between January 1, 2014 and January 31, 2017, and who had audiometric evaluation before surgery. Patients were classified as having either normal hearing or hearing loss based on pure-tone average in the better ear. A Generalized Estimating Equations approach was used to fit multivariable regression models for outcome variables of interest.

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An Economic Evaluation of Australia's Newborn Hearing Screening Program: A Within-Study Cost-Effectiveness Analysis.

Sharma, Rajan 1; Gu, Yuanyuan 1; Sinha, Kompal 2; Ching, Teresa Y. C. 3; Marnane, Vivienne 3; Gold, Lisa 4; Wake, Melissa 5; Wang, Jing 5; Parkinson, Bonny 1

doi : 10.1097/AUD.0000000000001153

pg. 972-983

Hearing loss is one of the most prevalent congenital disorders among children. Many countries have implemented universal newborn hearing screening (UNHS) for the early diagnosis and treatment of hearing loss. Despite widespread implementation, the value for money of UNHS is unclear due to lack of cost and outcomes data from rigorous study designs. The objective of this research is to conduct a within-study cost-effectiveness analysis of UNHS compared with targeted screening (targeting children with risk factors of hearing loss) from the Australian healthcare system perspective.

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The Associations of Hearing Sensitivity and Different Cognitive Functions with Perception of Speech-in-Noise.

Merten, Natascha 1,2; Boenniger, Meta M. 1; Herholz, Sibylle C. 1; Breteler, Monique M.B. 1,3

doi : 10.1097/AUD.0000000000001154

pg. 984-992

Impaired speech-in-noise perception affects individuals' daily lives and is a frequent symptom of age-related hearing loss, which is a common disabling condition and a health concern in aging populations. The relative impact of hearing sensitivity loss and different cognitive functions on speech-in-noise perception is not well understood. We aimed to assess to what extent hearing sensitivity and different cognitive functions were associated with sentence-in-noise performance across the adult lifespan.

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Preoperative Visual Measures of Verbal Learning and Memory and their Relations to Speech Recognition After Cochlear Implantation.

Ray, Christin 1; Pisoni, David B. 2; Lu, Emily 1; Kronenberger, William G. 2,3; Moberly, Aaron C. 1

doi : 10.1097/AUD.0000000000001155

pg. 993-1002

This study examined the performance of a group of adult cochlear implant (CI) candidates (CIC) on visual tasks of verbal learning and memory. Preoperative verbal learning and memory abilities of the CIC group were compared with a group of older normal-hearing (ONH) control participants. Relations between preoperative verbal learning and memory measures and speech recognition outcomes after 6 mo of CI use were also investigated for a subgroup of the CICs.

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Evaluating the Association Between Hearing Loss and Falls in Adults With Vestibular Dysfunction or Nonvestibular Dizziness.

Huang, Ryan J. 1; Pieper, Carl F. 2; Whitson, Heather E. 3,4,5,6; Garrison, Douglas B. 1; Pavon, Juliessa M. 3,4; Riska, Kristal M. 1,3

doi : 10.1097/AUD.0000000000001156

pg. 1003-1012

Although emerging evidence suggests that hearing loss (HL) is an independent risk factor for falls, it is unclear how HL may impact falls risk in adults with vestibular dysfunction and nonvestibular dizziness. The purpose of this study was to characterize the impact of HL on falls in patients with vestibular dysfunction and nonvestibular dizziness relative to a group of patients without dizziness. In addition, this study aimed to evaluate whether there was an interactive effect between HL and vestibular dysfunction or nonvestibular dizziness on the odds of falling.

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Acceptable Noise Levels and Preferred Signal-to-noise Ratios for Speech and Music.

Lee, Donguk; Lewis, James D.; Johnstone, Patti M.; Plyler, Patrick N.

doi : 10.1097/AUD.0000000000001157

pg. 1013-1022

The objective of this study was to evaluate the influence of music versus speech on a listener's signal-to-noise ratio (SNR) preferences when listening in a noise background. SNR preferences were quantified using acceptable noise level (ANL) and preferred SNR metrics. The measurement paradigm for ANL allows the listener to adjust the level of background noise while listening to the target at their most comfortable loudness level. A higher ANL indicates less tolerance for noise and a lower ANL indicates high tolerance for noise. The preferred SNR is simply the SNR the listener prefers when attending to a target in a fixed-amount (level) of background noise. In contrast to the ANL, the listener does not have control over the noise.

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AudioChip: A Deep Phenotyping Approach for Deconstructing and Quantifying Audiological Phenotypes of Self-Reported Speech Perception Difficulties.

Bhatt, Ishan Sunilkumar 1; Dias, Raquel 2; Wineinger, Nathan 2; Pratt, Sheila 3; Wang, Jin 4; Washnik, Nilesh 5; Guthrie, O'neil 6; Wilder, Jason 7; Torkamani, Ali 2

doi : 10.1097/AUD.0000000000001158

pg. 1023-1036

About 15% of U.S. adults report speech perception difficulties despite showing normal audiograms. Recent research suggests that genetic factors might influence the phenotypic spectrum of speech perception difficulties. The primary objective of the present study was to describe a conceptual framework of a deep phenotyping method, referred to as AudioChipping, for deconstructing and quantifying complex audiometric phenotypes.

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Diotic and Antiphasic Digits-in-noise Testing as a Hearing Screening and Triage Tool to Classify Type of Hearing Loss.

De Sousa, Karina C. 1; Smits, Cas 2; Moore, David R. 3,4; Myburgh, Hermanus C. 5; Swanepoel, De Wet 1,6

doi : 10.1097/AUD.0000000000001160

pg. 1037-1048

The digits-in-noise test (DIN) is a popular self-test measure that has traditionally been used to screen for hearing loss by providing either a pass or refer result. Standard approaches either tested each ear monaurally or used a binaural diotic version where identical digits and noise were presented simultaneously to both ears. Recently, a dichotic, antiphasic version was developed, increasing sensitivity of the DIN to unilateral or asymmetric sensorineural hearing loss (SNHL) and conductive hearing loss (CHL). The purpose of this study was to determine predictors and normative ranges of the antiphasic and diotic DIN and to determine if a combination of diotic and antiphasic DIN could accurately categorize hearing into (1) normal, (2) bilateral SNHL, or (3) unilateral SNHL or CHL.

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Diagnostic Yield of Targeted Hearing Loss Gene Panel Sequencing in a Large German Cohort With a Balanced Age Distribution from a Single Diagnostic Center: An Eight-year Study.

Tropitzsch, Anke 1; Schade-Mann, Thore 1; Gamerdinger, Philipp 1; Dofek, Saskia 1; Schulte, Bjorn 2; Schulze, Martin 2; Battke, Florian 2; Fehr, Sarah 2; Biskup, Saskia 2; Heyd, Andreas 1; Muller, Marcus 1; Lowenheim, Hubert 1; Vona, Barbara 1; Holderried, Martin 1,3

doi : 10.1097/AUD.0000000000001159

pg. 1049-1066

Hereditary hearing loss exhibits high degrees of genetic and clinical heterogeneity. To elucidate the population-specific and age-related genetic and clinical spectra of hereditary hearing loss, we investigated the sequencing data of causally associated hearing loss genes in a large cohort of hearing-impaired probands with a balanced age distribution from a single center in Southwest Germany.

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Cost-Effectiveness of Screening Preschool Children for Hearing Loss in Australia.

Gumbie, Mutsa 1; Parkinson, Bonny 1; Dillon, Harvey 2; Bowman, Ross 1; Song, Rachel 1; Cutler, Henry 1

doi : 10.1097/AUD.0000000000001134

pg. 1067-1078

While all newborns in Australia are tested for congenital hearing loss through universal newborn hearing screening programs, some children will acquire hearing loss in their first five years of life. Delayed diagnosed or undiagnosed hearing loss in children can have substantial immediate- and long-term consequences. It can significantly reduce school readiness, language and communication development, social and emotional development, and mental health. It can also compromise lifetime educational achievements and employment opportunities and future economic contribution to society through lost productivity. The need for a universal hearing screening program for children entering their first year of primary school has been noted in two separate Australian Government hearing inquiries in the last decade. Sound Scouts is a hearing screening application (app) that tests for hearing loss in children using a tablet or mobile device, supervised by parents at home. It tests for sensorineural or permanent conductive hearing loss and central auditory processing disorder in children. In 2018 the Australian Government funded the roll-out of Sound Scouts to allow up to 600,000 children to test their hearing using Sound Scouts. This study estimated the cost-effectiveness of screening 5-year-old children for hearing loss using Sound Scouts at home, compared with no screening.

خرید پکیج و مشاهده آنلاین مقاله


A Predictive Model of Bilateral Sensorineural Hearing Loss in Meniere Disease Using Clinical Data.

Moleon, M. D. Carmen 1,2; Torres-Garcia, Lidia 3; Batuecas-Caletrio, Angel 4; Castillo-Ledesma, Natalia 5; Gonzalez-Aguado, Rocio 5; Magnoni, Laura 6; Rossi, Marcos 7; Di Berardino, Federica 6; Perez-Guillen, Vanesa 3; Trinidad-Ruiz, Gabriel 8; Lopez-Escamez, Jose A. 1,2,9

doi : 10.1097/AUD.0000000000001169

pg. 1079-1085

Meniere disease (MD) is defined by a clinical syndrome of recurrent attacks of spontaneous vertigo associated with tinnitus, aural fullness, and sensorineural hearing loss (SNHL). Most patients have unilateral SNHL, but some of them will develop contralateral SNHL during the course of the disease. Several studies have reported a frequency of 2 to 73% SNHL in the second ear, according to the duration of disease and the period of follow-up. We hypothesize that unilateral and bilateral MD are different conditions, the first would initially involve the apical turn of the cochlea, while bilateral MD would affect the entire length of the cochlea.

خرید پکیج و مشاهده آنلاین مقاله


Letter to the Editor: Comment on "Evaluating the Efficacy of Intratympanic Dexamethasone in Protecting Against Irreversible Hearing Loss in Patients on Cisplatin-Based Cancer Treatment: A Randomized Controlled Phase IIIB Clinical Trial" (Moreno and Belinchon 2022).

Shupak, Avi

doi : 10.1097/AUD.0000000000001209

pg. 1086-1087

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