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ISSLS PRIZE in Clinical Science 2022: Epidemiology, risk factors and clinical impact of juvenile Modic changes in paediatric patients with low back pain
G. Michael Mallow, David Zepeda, Timothy G. Kuzel, J. Nicolas Barajas, Khaled Aboushaala, Michael T. Nolte, Alejandro Espinoza-Orias, Chundo Oh, Matth
doi : 10.1007/s00586-022-07125-x
Volume 31, issue 5, May 2022
It’s a long-held belief that Modic changes (MC) occur only in adults, with advanced age, and are highly associated with pain and adverse outcomes. The following study addressed the epidemiology, risk factors and clinical relevance of MC in young paediatric patients.
ISSLS prize in clinical science 2022: accelerated disc degeneration after pubertal growth spurt differentiates adults with low back pain from their asymptomatic peers
Anni Aavikko, Martina Lohman, Leena Ristolainen, Hannu Kautiainen, Kalevi ?sterman, Dietrich Schlenzka & Teija Lund
doi : 10.1007/s00586-022-07184-0
European Spine Journal volume 31, pages 1080–1087 (2022)
In this prospective observational cohort study, the development of lumbar intervertebral discs (LIVD) on magnetic resonance imaging (MRI) was investigated from childhood to adulthood with emphasis on the possible association of disc degeneration (DD) to low back pain (LBP).
ISSLS Prize in Bioengineering Science 2022: low rate cyclic loading as a therapeutic strategy for intervertebral disc regeneration
Elizabeth A. Capogna, Emma Brown, Evan Walrath, William Furst, Qing Dong, Chao-Ming Zhou, Sarah E. Gullbrand, Nam V. Vo, Gwendolyn A. Sowa & Eric H. L
doi : 10.1007/s00586-022-07239-2
European Spine Journal volume 31, pages 1088–1098 (2022)
The intervertebral disc degenerates with age and has a poor propensity for regeneration. Small molecule transport plays a key role in long-term degradation and repair. Convection (bulk flow), induced by low rate cyclic loading of the intervertebral disc, has been shown to increase transport of small molecules. However, the potential therapeutic benefit of low rate cyclic loading on degenerated discs has not been described. The purpose of this study was to determine if a sustained (daily) low rate cyclic loading regimen could slow, arrest, or reverse intervertebral disc degeneration in the rabbit lumbar spine.
Georg schmorl prize of the German spine society (DWG) 2021: Spinal Instability Spondylodiscitis Score (SISS)—a novel classification system for spinal instability in spontaneous spondylodiscitis
Friederike Sch?mig, Zhao Li, Lena Perka, Tu-Lan Vu-Han, Torsten Diekhoff, Charles G. Fisher & Matthias Pumberger
doi : 10.1007/s00586-022-07157-3
European Spine Journal volume 31, pages 1099–1106 (2022)
Even though spinal infections are associated with high mortality and morbidity, their therapy remains challenging due to a lack of established classification systems and widely accepted guidelines for surgical treatment. This study’s aim therefore was to propose a comprehensive classification system for spinal instability based on the Spinal Instability Neoplastic Score (SINS) aiding spine surgeons in choosing optimal treatment for spontaneous spondylodiscitis.
Grammer european spine journal award for basic science and applied research 2020/2021
doi : 10.1007/s00586-022-07221-y
European Spine Journal volume 31, page 1107 (2022)
Establishment and validation of a nomogram and web calculator for the risk of new vertebral compression fractures and cement leakage after percutaneous vertebroplasty in patients with osteoporotic vertebral compression fractures
Wenle Li, Haosheng Wang, Shengtao Dong, Zhi-Ri Tang, Longhao Chen, Xintian Cai, Zhaohui Hu & Chengliang Yin
doi : 10.1007/s00586-021-07064-z
European Spine Journal volume 31, pages 1108–1121 (2022)
The aim of this work was to investigate the risk factors for cement leakage and new-onset OVCF after Percutaneous vertebroplasty (PVP) and to develop and validate a clinical prediction model (Nomogram).
High- versus low-viscosity cement vertebroplasty and kyphoplasty for osteoporotic vertebral compression fracture: a meta-analysis
Qiang Wang, Changtai Sun, Liang Zhang, Lin Wang, Quan Ji, Nan Min & Zilong Yin
doi : 10.1007/s00586-022-07150-w
European Spine Journal volume 31, pages 1122–1130 (2022)
To compare high- versus low-viscosity bone cement on the clinical outcomes and complications in patients with Osteoporotic vertebral compression fractures (OVCFs) who underwent percutaneous vertebroplasty (PVP) or percutaneous kyphoplasty (PKP).
MRI-based vertebral bone quality score effectively reflects bone quality in patients with osteoporotic vertebral compressive fractures
Ruoyao Li, Yongjie Yin, Wei Ji, Xiaoliang Wu, Hui Jiang, Jianting Chen & Qingan Zhu
doi : 10.1007/s00586-022-07177-z
European Spine Journal volume 31, pages 1131–1137 (2022)
The present study is aimed to validate the ability of the vertebral bone quality (VBQ) score to evaluate bone quality in patients with osteoporotic vertebral compression fractures (OVCF) and to compare it with the ability of T-score by DXA. In addition, the sensitivity of VBQ score with cerebrospinal fluid (CSF) of L2 and L3 segments as baseline is evaluated.
Dorsal instrumentation with and without vertebral body replacement in patients with thoracolumbar osteoporotic fractures shows comparable outcome measures
Maximilian Schwendner, Stefan Motov, Yu-Mi Ryang, Bernhard Meyer & Sandro M. Krieg
doi : 10.1007/s00586-021-07044-3
European Spine Journal volume 31, pages 1138–1146 (2022)
In the surgical treatment of osteoporotic spine fractures, there is no clear recommendation, which treatment is best for the individual patient with vertebra plana and/or neurological deficit requiring instrumentation. The aim of this study was to evaluate clinical and radiological outcomes after dorsal or 360° instrumentation of osteoporotic fractures of the thoracolumbar spine in a cohort of patients representing clinical reality.
Value of MRI in assessing back pain after thoracolumbar osteoporotic vertebral compression fractures and discussion on the underlying mechanisms by tissue biopsy
Haoran Qi, Jun Qi, Ye Sun, Junying Gao, Jianmin Sun & Guodong Wang
doi : 10.1007/s00586-021-07095-6
European Spine Journal volume 31, pages 1147–1157 (2022)
The specific radiological feature of osteoporotic vertebral compression fractures (OVCFs) is bone marrow oedema (BME) on magnetic resonance imaging (MRI). However, the relationship between BME and back pain (BP) is unclear. We investigated the value of MRI in assessing BP and discussed the relevant mechanisms by tissue biopsy.
A 2-year longitudinal study of skeletal muscle mass in women over 40Â years of age with degenerative lumbar scoliosis
Masaya Mizutani, Yawara Eguchi, Toru Toyoguchi, Sumihisa Orita, Kazuhide Inage, Yasuhiro Shiga, Takeo Furuya, Satoshi Maki, Junichi Nakamura, Shigeo H
doi : 10.1007/s00586-021-07038-1
European Spine Journal volume 31, pages 1158–1165 (2022)
We investigated changes in skeletal muscle mass and bone mineral density in degenerative lumbar scoliosis (DLS) patients during a 2-year follow-up following diagnosis.
Impact of radiologic variables on item responses of ODI, SRS22 and SF-36. in adult spinal deformity patients: differential item functioning (DIF) analysis results from a multi-center database
D. C. Kieser, S. Yuksel, L. Boissiere, C. Yilgor, D. T. Cawley, K. Hayashi, A. Alanay, F. S. Kleinstueck, F. Pellise, F. J. S. Perez-Grueso, Vital Jea
doi : 10.1007/s00586-021-07088-5
European Spine Journal volume 31, pages 1166–1173 (2022)
To determine if responses given to each question of the Scoliosis Research Society-22 (SRS22), Oswestry disability index (ODI) and Short Form-36 (SF-36) questionnaires are influenced by the radiological parameters.
Surgeons’ risk perception in ASD surgery: The value of objective risk assessment on decision making and patient counselling
Ferran Pellisé, Alba Vila-Casademunt, Susana N??ez-Pereira, Sleiman Haddad, Justin S. Smith, Michael P. Kelly, Ahmet Alanay, Christopher Shaffrey, Jav
doi : 10.1007/s00586-022-07166-2
European Spine Journal volume 31, pages 1174–1183 (2022)
Surgeons often rely on their intuition, experience and published data for surgical decision making and informed consent. Literature provides average values that do not allow for individualized assessments. Accurate validated machine learning (ML) risk calculators for adult spinal deformity (ASD) patients, based on 10Â year multicentric prospective data, are currently available. The objective of this study is to assess surgeon ASD risk perception and compare it to validated risk calculator estimates.
Health-related quality of life measures in adult spinal deformity: can we replace the SRS-22 with PROMIS?
Peter G. Passias, Katherine E. Pierce, Oscar Krol, Tyler Williamson, Sara Naessig, Waleed Ahmad, Lara Passfall, Peter Tretiakov, Bailey Imbo, Rachel J
doi : 10.1007/s00586-021-07106-6
European Spine Journal volume 31, pages 1184–1188 (2022)
To determine the validity and responsiveness of PROMIS metrics versus the SRS-22r questionnaire in adult spinal deformity (ASD).
Non-surgical treatment for adult spinal deformity: results of an intensive combined physical and psychological programme for patients with adult spinal deformity and chronic low back pain—a treatment-based cohort study
Evelien H. W. Hoevenaars, Michiel Beekhuizen, John O’Dowd, Maarten Spruit & Miranda L. van Hooff
doi : 10.1007/s00586-022-07156-4
European Spine Journal volume 31, pages 1189–1196 (2022)
No evidence-based treatment exists for adult spinal deformity (ASD) patients with chronic low back pain (CLBP). Aim of this study: evaluate a combined physical and psychological programme (CPPP) for ASD patients with CLBP and to compare this with a non-ASD-cohort with CLBP.
Kickstand rods and correction of coronal malalignment in patients with adult spinal deformity
Gregory M. Mundis Jr., Corey T. Walker, Justin S. Smith, Thomas J. Buell, Renaud Lafage, Christopher I. Shaffrey, Robert K. Eastlack, David O. Okonkwo
doi : 10.1007/s00586-022-07161-7
European Spine Journal volume 31, pages 1197–1205 (2022)
Coronal malalignment (CM) is a challenging spinal deformity to treat. The kickstand rod (KR) technique is powerful for correcting truncal shift. This study tested the hypothesis that the KR technique provides superior coronal alignment correction in adult deformity compared with traditional rod techniques.
Cost-effectiveness of anterior surgical decompression surgery for cervical degenerative disk disease: a systematic review of economic evaluations
V. N. E. Schuermans, A. Y. J. M. Smeets, A. F. M. Boselie, O. Zarrouk, S. M. M. Hermans, R. Droeghaag, I. Curfs, S. M. A. A. Evers & H. van Santbrink
doi : 10.1007/s00586-022-07137-7
European Spine Journal volume 31, pages 1206–1218 (2022)
No clear consensus exists on which anterior surgical technique is most cost-effective for treating cervical degenerative disk disease (CDDD). One of the most common treatment options is anterior cervical discectomy with fusion (ACDF). Anterior cervical discectomy with arthroplasty (ACDA) was developed in an effort to reduce the incidence of clinical adjacent segment pathology and associated additional surgeries by preserving motion. This systematic review aims to evaluate the evidence regarding the cost-effectiveness of anterior surgical decompression techniques used to treat radiculopathy and/or myelopathy caused by CDDD.
A sheep model of chronic cervical compressive myelopathy via an implantable wireless compression device
Zihe Li, Shuheng Zhai, Shanshan Liu, Chunhua Chen, Xinhu Guo, Panpan Hu, Ben Wang, Youyu Zhang, Feng Wei & Zhongjun Liu
doi : 10.1007/s00586-022-07138-6
European Spine Journal volume 31, pages 1219–1227 (2022)
This study aimed to establish an animal model in which we can precisely displace the spinal cord and therefore mimic the chronic spinal compression of cervical spondylotic myelopathy.
Variation of cervical sagittal alignment parameters according to gender, pelvic incidence and age
Yann Philippe Charles, Solène Prost, Sébastien Pesenti, Brice Ilharreborde, Eloïse Bauduin, Féthi Laouissat, Guillaume Riouallon, Stéphane Wolff, Vinc
doi : 10.1007/s00586-021-07102-w
European Spine Journal volume 31, pages 1228–1240 (2022)
The aim was to describe radiographic cervical sagittal alignment variations according to age, gender and pelvic incidence (PI) and to investigate relationships with thoracic alignment.
Suitability of 3.5-mm screw for the atlas in children: a retrospective computed tomography analysis
Jiarui Chen, Tuo Liang, Yajie Hu, Youliang Ma, Shengsheng Huang, Liyi Chen, Jie Jiang, Hao Li, Tianyou Chen, Jiemei Cen, Chong Liu & Xinli Zhan
doi : 10.1007/s00586-022-07136-8
European Spine Journal volume 31, pages 1241–1250 (2022)
The growth and development of the atlas in children has not been studied to date using a large sample size.
The medial window technique as a salvage method to insert C2 pedicle screw in the case of a high-riding vertebral artery or narrow pedicle: a technical note and case series
Dong-Ho Lee, Sehan Park, Jae Hwan Cho, Chang Ju Hwang, Hyung Rae Lee, Sang Yun Seok & Choon Sung Lee
doi : 10.1007/s00586-022-07146-6
European Spine Journal volume 31, pages 1251–1259 (2022)
To describe the safety and feasibility of C2 medial window screw (C2MWS) as an alternative salvage method for C2 pedicle screws in cases of high-riding vertebral artery (HRVA) or narrow pedicle.
ProDisc–C versus anterior cervical discectomy and fusion for the surgical treatment of symptomatic cervical disc disease: two-year outcomes of Asian prospective randomized controlled multicentre study
Naresh Kumar, Zhong Jun Liu, Wai Sang Poon, Chun-Kun Park, Ruey-Mo Lin, Kyoung-Suok Cho, Chi Chien Niu, Hung Yi Chen, Sirisha Madhu, Liang Shen, Yu Su
doi : 10.1007/s00586-021-07055-0
European Spine Journal volume 31, pages 1260–1272 (2022)
Our study aimed to evaluate non-inferiority of ProDisc-C to anterior cervical discectomy and fusion (ACDF) in terms of clinical outcomes and incidence of adjacent segment disease (ASD) at 24-months post-surgery in Asian patients with symptomatic cervical disc disease (SCDD).
Midterm osteolysis-induced aseptic failure of the M6-Câ„¢ cervical total disc replacement secondary to polyethylene wear debris
Matthew Scott-Young, Evelyne Rathbone & Lauren Grierson
doi : 10.1007/s00586-021-07094-7
European Spine Journal volume 31, pages 1273–1282 (2022)
According to published meta-analyses, cervical total disc replacement (CTDR) seems to be superior to anterior cervical decompression and fusion (ACDF) in most clinical parameters. Despite short-term clinical success of CTDR, there are concerns regarding long-term durability of these prostheses.
Classification and regression tree (CART) model to assist clinical prediction for tracheostomy in patients with traumatic cervical spinal cord injury: a 7-year study of 340 patients
Dawei Sun, Hanqing Zhao & Zhengfeng Zhang
doi : 10.1007/s00586-022-07154-6
European Spine Journal volume 31, pages 1283–1290 (2022)
To develop a classification and regression tree (CART) model to predict the need of tracheostomy in patients with traumatic cervical spinal cord injury (TCSCI) and to quantify scores of risk factors to make individualized clinical assessments.
Predictors of failure to achieve minimal clinical important difference for pain and disability after mechanical diagnosis and therapy (MDT)-based multimodal rehabilitation for neck pain: a retrospective analysis of 4998 patients
Gautam M. Shetty, Palak Vakil, Shikha Jain, Garima Anandani & C. S. Ram
doi : 10.1007/s00586-022-07167-1
European Spine Journal volume 31, pages 1291–1299 (2022)
To determine predictors of failure to achieve minimal clinical important difference (MCID) for pain and disability at discharge after mechanical diagnosis and therapy (MDT)-based multimodal rehabilitation for neck pain (NP).
Effectiveness of laminectomy with fusion and laminectomy alone in degenerative cervical myelopathy
David Fr?jd Revesz, Anastasios Charalampidis & Paul Gerdhem
doi : 10.1007/s00586-022-07159-1
European Spine Journal volume 31, pages 1300–1308 (2022)
The effectiveness of laminectomy with fusion and laminectomy alone in degenerative cervical myelopathy was compared.
Evaluating prehospital care of patients with potential traumatic spinal cord injury: scoping review
Roya Habibi Arejan, Mohammad Hossein Asgardoon, Maryam Shabany, Zahra Ghodsi, Hamid Reza Dehghan, Masoud Sohrabi Asl, Hamidreza Ostadrahimi, Alex R. V
doi : 10.1007/s00586-022-07164-4
European Spine Journal volume 31, pages 1309–1329 (2022)
To gain insight into current research regarding prehospital care (PHC) in patients with potential traumatic spinal cord injury (TSCI) and to disseminate the findings to the research community.
Correction to: Variation of cervical sagittal alignment parameters according to gender, pelvic incidence and age
Yann Philippe Charles, Solène Prost, Sébastien Pesenti, Brice Ilharreborde, Eloïse Bauduin, Féthi Laouissat, Guillaume Riouallon, Stéphane Wolff, Vinc
doi : 10.1007/s00586-022-07170-6
European Spine Journal volume 31, page 1330 (2022)
Correction to: Closed‑suction drainage in thoracolumbar spinal surgery–clinical routine without evidence? a systematic review
Klaus John Schnake, Matthias Pumberger, Denis Rappert, Achim G?tz, Oleksandr Zolotoverkh, Rita Waligora, Max Joseph Scheyerer & Spine Section of the G
doi : 10.1007/s00586-022-07171-5
European Spine Journal volume 31, page 1331 (2022)
