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To stent or not to stent? Treating angina after ISCHEMIA—the impact of the ISCHEMIA trial on the indications for angiography and revascularization in patients with stable coronary artery disease
Bernard J Gersh, Deepak L Bhatt
doi : 10.1093/eurheartj/ehab069.001
European Heart Journal, Volume 42, Issue 14, 7 April 2021, Pages 1389–1393
To stent or not to stent? Treating angina after ISCHEMIA—why a conservative approach with optimal medical therapy is the preferred initial management strategy for chronic coronary syndromes: insights from the ISCHEMIA trial
William E Boden, Peter H Stone
doi : 10.1093/eurheartj/ehab069.002
European Heart Journal, Volume 42, Issue 14, 7 April 2021, Pages 1394–1400
Guidelines on myocardial infarction, novel therapeutic targets in post-infarction remodelling, and a debate on the ISCHEMIA trial
Filippo Crea
doi : 10.1093/eurheartj/ehab173
European Heart Journal, Volume 42, Issue 14, 7 April 2021, Pages 1277–1280
Dr Raphael Twerenbold
Mark Nicholls
doi : 10.1093/eurheartj/ehaa315
European Heart Journal, Volume 42, Issue 14, 7 April 2021, Pages 1281–1282
Xenotransplantation in the era of a zoonotic pandemic
Felix Schoenrath, Volkmar Falk, Maximilian Y Emmert
doi : 10.1093/eurheartj/ehaa1101
European Heart Journal, Volume 42, Issue 14, 7 April 2021, Pages 1283–1285
Jiri Widimsky MD
Petr Widimsky, MD, DrSc, FESC
doi : 10.1093/eurheartj/ehaa1107
European Heart Journal, Volume 42, Issue 14, 7 April 2021, Pages 1285–1286
Interleukin-1 blockade: a paradigm shift in the treatment of patients with recurrent pericarditis?
Giovanna Liuzzo, MD, PhD, FESC, Carlo Patrono, MD, FESC
doi : 10.1093/eurheartj/ehab100
European Heart Journal, Volume 42, Issue 14, 7 April 2021, Pages 1287–1288
2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC)
Jean-Philippe Collet, Holger Thiele, Emanuele Barbato, Olivier Barthélémy, Johann Bauersachs
doi : 10.1093/eurheartj/ehaa575
European Heart Journal, Volume 42, Issue 14, 7 April 2021, Pages 1289–1367
Questions and answers on antithrombotic therapy and revascularization strategies in non-ST-elevation acute coronary syndrome (NSTE-ACS): a companion document of the 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation
Emanuele Barbato, Julinda Mehilli, Dirk Sibbing, George C M Siontis, Jean-Philippe Collet
doi : 10.1093/eurheartj/ehaa601
European Heart Journal, Volume 42, Issue 14, 7 April 2021, Pages 1368–1378
Questions and answers on workup diagnosis and risk stratification: a companion document of the 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation
Olivier Barthélémy, Alexander Jobs, Emanuele Meliga, Christian Mueller, Frans H Rutten
doi : 10.1093/eurheartj/ehaa602
European Heart Journal, Volume 42, Issue 14, 7 April 2021, Pages 1379–1386
To stent or not to stent? Treating angina after ISCHEMIA—introduction
Bernard J Gersh, William E Boden, Deepak L Bhatt, Peter H Stone, Filippo Crea
doi : 10.1093/eurheartj/ehab069
European Heart Journal, Volume 42, Issue 14, 7 April 2021, Pages 1387–1400
Validation of the European Society of Cardiology pre-test probability model for obstructive coronary artery disease
Simon Winther, Samuel Emil Schmidt, Laust Dupont Rasmussen, Luis Eduardo Ju?rez Orozco, Flemming Hald Steffensen ...
doi : 10.1093/eurheartj/ehaa755
European Heart Journal, Volume 42, Issue 14, 7 April 2021, Pages 1401–1411
Estimation of pre-test probability (PTP) of disease in patients with suspected coronary artery disease (CAD) is a common challenge. Due to decreasing prevalence of obstructive CAD in patients referred for diagnostic testing, the European Society of Cardiology suggested a new PTP (2019-ESC-PTP) model. The aim of this study was to validate that model.
Coronary stenoses in patients suspected to have obstructive coronary artery disease: the exemption rather than the rule!
Udo Sechtem, Peter Ong
doi : 10.1093/eurheartj/ehaa762
European Heart Journal, Volume 42, Issue 14, 7 April 2021, Pages 1412–1414
The role of G protein-coupled receptor kinase 4 in cardiomyocyte injury after myocardial infarction
Liangpeng Li, Wenbin Fu, Xue Gong, Zhi Chen, Luxun Tang
doi : 10.1093/eurheartj/ehaa878
European Heart Journal, Volume 42, Issue 14, 7 April 2021, Pages 1415–1430
G protein-coupled receptor kinase 4 (GRK4) has been reported to play an important role in hypertension, but little is known about its role in cardiomyocytes and myocardial infarction (MI). The goal of present study is to explore the role of GRK4 in the pathogenesis and progression of MI.
Adding another GRK to the fire of heart failure
Rajika Roy, Walter J Koch
doi : 10.1093/eurheartj/ehaa847
European Heart Journal, Volume 42, Issue 14, 7 April 2021, Pages 1431–1432
The association between coronary graft patency and clinical status in patients with coronary artery disease
Mario Gaudino, Antonino Di Franco, Deepak L Bhatt, John H Alexander, Antonio Abbate
doi : 10.1093/eurheartj/ehab096
European Heart Journal, Volume 42, Issue 14, 7 April 2021, Pages 1433–1441
The concept of a direct association between coronary graft patency and clinical status is generally accepted. However, the relationship is more complex and variable than usually thought. Key issues are the lack of a common definition of graft occlusion and of a standardized imaging protocol for patients undergoing coronary bypass surgery. Factors like the type of graft, the timing of the occlusion, and the amount of myocardium at risk, as well as baseline patients’ characteristics, modulate the patency-to-clinical status association. Available evidence suggests that graft occlusion is more often associated with non-fatal events rather than death. Also, graft failure due to competitive flow is generally a benign event, while graft occlusion in a graft-dependent circulation is associated with clinical symptoms. In this systematic review, we summarize the evidence on the association between graft status and clinical outcomes.
Coronary flow velocity reserve adds prognostic information beyond presence or absence of non-obstructive coronary atherosclerosis
Jakob Schroder, Eva Prescott
doi : 10.1093/eurheartj/ehab064
European Heart Journal, Volume 42, Issue 14, 7 April 2021, Pages 1442–1443
Is coronary flow velocity reserve just a marker of a higher atherosclerotic burden?
Francesco Radico, Marco Zimarino, Raffaele De Caterina
doi : 10.1093/eurheartj/ehab062
European Heart Journal, Volume 42, Issue 14, 7 April 2021, Pages 1444–1445
Pneumopericardium
Ammar Nazir, Mohaned Egred
doi : 10.1093/eurheartj/ehaa692
European Heart Journal, Volume 42, Issue 14, 7 April 2021, Page 1445
A rescued left ventricle free wall rupture in MINOCA
Alessandra Giavarini, Sonia Ippolito, Maria Isabella Tagliasacchi, Guido Gelpi
doi : 10.1093/eurheartj/ehaa1048
European Heart Journal, Volume 42, Issue 14, 7 April 2021, Page 1446
Corrigendum to: The year in cardiovascular medicine 2020: heart failure and cardiomyopathies
doi : 10.1093/eurheartj/ehab055
European Heart Journal, Volume 42, Issue 14, 7 April 2021, Page 1378
Corrigendum to: Predicted Benefit of an Implantable Cardioverter-Defibrillator: The MADIT-ICD Benefit Score
doi : 10.1093/eurheartj/ehab048
European Heart Journal, Volume 42, Issue 14, 7 April 2021, Page 1441
Corrigendum to: Procedural myocardial injury, infarction and mortality in patients undergoing elective PCI: a pooled analysis of patient-level data
doi : 10.1093/eurheartj/ehab073
European Heart Journal, Volume 42, Issue 14, 7 April 2021, Page 1443
