دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه
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Molecular pathology and biomarker of progression in Alzheimer’s disease
Masud Husain
doi : 10.1093/brain/awac209
Volume 145, Issue 7, July 2022
Homeostatic feelings and the biology of consciousness
Antonio Damasio, Hanna Damasio
doi : 10.1093/brain/awac194
Towards adaptive deep brain stimulation for freezing of gait
Huiling Tan
doi : 10.1093/brain/awac172
Do genetic factors contribute to sex-specific differences in resilience to amyloid pathology?
Colin Groot, Henne Holstege, Rik Ossenkoppele
doi : 10.1093/brain/awac216
How COVID-19 affects microvessels in the brain
Jan Wenzel, Markus Schwaninger
doi : 10.1093/brain/awac211
Pre-symptomatic spinal muscular atrophy: a proposed nosology
Richard S Finkel, Michael Benatar
doi : 10.1093/brain/awac125
Reimagining cholinergic therapy for Alzheimer’s disease
Ezio Giacobini, A Claudio Cuello, Abraham Fisher
doi : 10.1093/brain/awac096
Neurovascular coupling mechanisms in health and neurovascular uncoupling in Alzheimer’s disease
Winston M Zhu, Ain Neuhaus, Daniel J Beard, Brad A Sutherland, Gabriele C DeLuca
doi : 10.1093/brain/awac174
Distinct brainstem to spinal cord noradrenergic pathways inversely regulate spinal neuronal activity
Mateusz W Kucharczyk, Francesca Di Domenico, Kirsty Bannister
doi : 10.1093/brain/awac085
Biallelic ADAM22 pathogenic variants cause progressive encephalopathy and infantile-onset refractory epilepsy
Marieke M van der Knoop, Reza Maroofian, Yuko Fukata, Yvette van Ierland, Ehsan G Karimiani, Anna Elina Lehesjoki, Mikko Muona, Anders Paetau, Yuri Miyazaki, Yoko Hirano, Laila Selim, Marina de França, Rodrigo Ambrosio Fock, Christian Beetz, Claudia A L Ruivenkamp, Alison J Eaton, Francois D Morneau-Jacob, Lena Sagi-Dain, Lilach Shemer-Meiri, Amir Peleg, Jumana Haddad-Halloun, Daan J Kamphuis, Cacha M P C D Peeters-Scholte, Semra Hiz Kurul, Rita Horvath, Hanns Lochmüller, David Murphy, Stephan Waldmüller, Stephanie Spranger, David Overberg, Alison M Muir, Aboulfazl Rad, Barbara Vona, Firdous Abdulwahad, Sateesh Maddirevula, Inna S Povolotskaya, Victoria Y Voinova, Vykuntaraju K Gowda, Varunvenkat M Srinivasan, Fowzan S Alkuraya, Heather C Mefford, Majid Alfadhel, Tobias B Haack, Pasquale Striano, Mariasavina Severino, Masaki Fukata, Yvonne Hilhorst-Hofstee, Henry Houlden
doi : 10.1093/brain/awac116
Defective lipid signalling caused by mutations in PIK3C2B underlies focal epilepsy
Luca Gozzelino, Gaga Kochlamazashvili, Sara Baldassari, Albert Ian Mackintosh, Laura Licchetta, Emanuela Iovino, Yu Chi Liu, Caitlin A Bennett, Mark F Bennett, John A Damiano, Gábor Zsurka, Caterina Marconi, Tania Giangregorio, Pamela Magini, Marijn Kuijpers, Tanja Maritzen, Giuseppe Danilo Norata, Stéphanie Baulac, Laura Canafoglia, Marco Seri, Paolo Tinuper, Ingrid E Scheffer, Melanie Bahlo, Samuel F Berkovic, Michael S Hildebrand, Wolfram S Kunz, Lucio Giordano, Francesca Bisulli, Miriam Martini, Volker Haucke, Emilio Hirsch, Tommaso Pippucci
doi : 10.1093/brain/awac082
AMPK-mediated potentiation of GABAergic signalling drives hypoglycaemia-provoked spike-wave seizures
Kathryn A Salvati, Matthew L Ritger, Pasha A Davoudian, Finnegan O’Dell, Daniel R Wyskiel, George M P R Souza, Adam C Lu, Edward Perez-Reyes, Joshua C Drake, Zhen Yan, Mark P Beenhakker
doi : 10.1093/brain/awac037
Seizures initiate in zones of relative hyperexcitation in a zebrafish epilepsy model
James E Niemeyer, Poornima Gadamsetty, Chanwoo Chun, Sherika Sylvester, Jacob P Lucas, Hongtao Ma, Theodore H Schwartz, Emre R F Aksay
doi : 10.1093/brain/awac073
Glycogen synthase downregulation rescues the amylopectinosis of murine RBCK1 deficiency
Silvia Nitschke, Mitchell A Sullivan, Sharmistha Mitra, Charlotte R Marchioni, Jennifer P  Y Lee, Brandon H Smith, Saija Ahonen, Jun Wu, Erin E Chown, Peixiang Wang, Sara Petković, Xiaochu Zhao, Laura F DiGiovanni, Ami M Perri, Lori Israelian, Tamar R Grossman, Holly Kordasiewicz, Francisco Vilaplana, Kazuhiro Iwai, Felix Nitschke, Berge A Minassian
doi : 10.1093/brain/awac017
Harnessing cortical plasticity via gabapentinoid administration promotes recovery after stroke
Andrea Tedeschi, Molly J E Larson, Antonia Zouridakis, Lujia Mo, Arman Bordbar, Julia M Myers, Hannah Y Qin, Haven I Rodocker, Fan Fan, John J Lannutti, Craig A McElroy, Shahid M Nimjee, Juan Peng, W David Arnold, Lawrence D F Moon, Wenjing Sun
doi : 10.1093/brain/awac103
Multi-ancestry GWAS reveals excitotoxicity associated with outcome after ischaemic stroke
Laura Ibanez, Laura Heitsch, Caty Carrera, Fabiana H G Farias, Jorge L Del Aguila, Rajat Dhar, John Budde, Kristy Bergmann, Joseph Bradley, Oscar Harari, Chia Ling Phuah, Robin Lemmens, Alessandro A Viana Oliveira Souza, Francisco Moniche, Antonio Cabezas-Juan, Juan Francisco Arenillas, Jerzy Krupinksi, Natalia Cullell, Nuria Torres-Aguila, Elena Muiño, Jara Cárcel-Márquez, Joan Marti-Fabregas, Raquel Delgado-Mederos, Rebeca Marin-Bueno, Alejandro Hornick, Cristofol Vives-Bauza, Rosa Diaz Navarro, Silvia Tur, Carmen Jimenez, Victor Obach, Tomas Segura, Gemma Serrano-Heras, Jong Won Chung, Jaume Roquer, Carol Soriano-Tarraga, Eva Giralt-Steinhauer, Marina Mola-Caminal, Joanna Pera, Katarzyna Lapicka-Bodzioch, Justyna Derbisz, Antoni Davalos, Elena Lopez-Cancio, Lucia Muñoz, Turgut Tatlisumak, Carlos Molina, Marc Ribo, Alejandro Bustamante, Tomas Sobrino, Jose Castillo-Sanchez, Francisco Campos, Emilio Rodriguez-Castro, Susana Arias-Rivas, Manuel RodrÃguez-Yáñez, Christina Herbosa, Andria L Ford, Alonso Gutierrez-Romero, Rodrigo Uribe-Pacheco, Antonio Arauz, Iscia Lopes-Cendes, Theodore Lowenkopf, Miguel A Barboza, Hajar Amini, Boryana Stamova, Bradley P Ander, Frank R Sharp, Gyeong Moon Kim, Oh Young Bang, Jordi Jimenez-Conde, Agnieszka Slowik, Daniel Stribian, Ellen A Tsai, Linda C Burkly, Joan Montaner, Israel Fernandez-Cadenas, Jin Moo Lee, Carlos Cruchaga
doi : 10.1093/brain/awac080
Cortical phase-amplitude coupling is key to the occurrence and treatment of freezing of gait
Zixiao Yin, Guanyu Zhu, Yuye Liu, Baotian Zhao, Defeng Liu, Yutong Bai, Quan Zhang, Lin Shi, Tao Feng, Anchao Yang, Huanguang Liu, Fangang Meng, Wolf Julian Neumann, Andrea A Kühn, Yin Jiang, Jianguo Zhang
doi : 10.1093/brain/awac121
Establishing gene regulatory networks from Parkinson’s disease risk loci
Sophie L Farrow, William Schierding, Sreemol Gokuladhas, Evgeniia Golovina, Tayaza Fadason, Antony A Cooper, Justin M O’Sullivan
doi : 10.1093/brain/awac022
OnabotulinumtoxinA alters inflammatory gene expression and immune cells in chronic headache patients
Lisa Gfrerer, Wenjie Xu, William Austen, Jr, Sait Ashina, Agustin Melo-Carrillo, Maria Serena Longhi, Aubrey Manack Adams, Timothy Houle, Mitchell F Brin, Rami Burstein
doi : 10.1093/brain/awab461
The PACAP pathway is independent of CGRP in mouse models of migraine: possible new drug target?
Charlotte Ernstsen, Sarah L Christensen, Rikke H Rasmussen, Brian S Nielsen, Inger Jansen-Olesen, Jes Olesen, David M Kristensen
doi : 10.1093/brain/awac040
Metabolomic profiling in small vessel disease identifies multiple associations with disease severity
Eric L Harshfield, Caroline J Sands, Anil M Tuladhar, Frank Erik de Leeuw, Matthew R Lewis, Hugh S Markus
doi : 10.1093/brain/awac041
Shared brain transcriptomic signature in TDP-43 type A FTLD patients with or without GRN mutations
Cyril Pottier, Ligia Mateiu, Matthew C Baker, Mariely DeJesus-Hernandez, Cristina Teixeira Vicente, NiCole A Finch, Shulan Tian, Marka van Blitterswijk, Melissa E Murray, Yingxue Ren, Leonard Petrucelli, Björn Oskarsson, Joanna M Biernacka, Neill R Graff-Radford, Bradley F Boeve, Ronald C Petersen, Keith A Josephs, Yan W Asmann, Dennis W Dickson, Rosa Rademakers
doi : 10.1093/brain/awab437
Tubulin tyrosination regulates synaptic function and is disrupted in Alzheimer’s disease
Leticia Peris, Julie Parato, Xiaoyi Qu, Jean Marc Soleilhac, Fabien Lanté, Atul Kumar, Maria Elena Pero, José MartÃnez-Hernández, Charlotte Corrao, Giulia Falivelli, Floriane Payet, Sylvie Gory-Fauré, Christophe Bosc, Marian Blanca Ramirez, Andrew Sproul, Jacques Brocard, Benjamin Di Cara, Philippe Delagrange, Alain Buisson, Yves Goldberg, Marie Jo Moutin, Francesca Bartolini, Annie Andrieux
doi : 10.1093/brain/awab436
Matrix metalloproteinase 10 is linked to the risk of progression to dementia of the Alzheimer’s type
Pamela V Martino Adami, Adelina Orellana, Pablo GarcÃa, Luca Kleineidam, Emilio Alarcón-MartÃn, Laura Montrreal, Nuria Aguilera, Ana Espinosa, Carla Abdelnour, Maitee Rosende-Roca, Juan Pablo Tartari, Liliana Vargas, Ana Mauleón, Ester Esteban-De Antonio, Rogelio López-Cuevas, Maria Carolina Dalmasso, Rafael Campos Martin, Kayenat Parveen, Victor M Andrade Fuentes, Najaf Amin, Shahzad Ahmad, M Arfan Ikram, Piotr Lewczuk, Johannes Kornhuber, Oliver Peters, Lutz Frölich, Eckart Rüther, Jens Wiltfang, Lluis Tarraga, Merce Boada, Wolfgang Maier, Itziar de Rojas, Amanda Cano, Angela Sanabria, Montserrat Alegret, Isabel Hernández, Marta Marquié, Sergi Valero, Cornelia M van Duijn, Michael Wagner, Frank Jessen, Anja Schneider, MarÃa Eugenia Sáez Goñi, Antonio González Pérez, AgustÃn Ruiz, Alfredo RamÃrez
doi : 10.1093/brain/awac024
Cancer diagnosis is associated with a lower burden of dementia and less Alzheimer’s-type neuropathology
Shama D Karanth, Yuriko Katsumata, Peter T Nelson, David W Fardo, Jaclyn K McDowell, Frederick A Schmitt, Richard J Kryscio, Steven R Browning, Dejana Braithwaite, Susanne M Arnold, Erin L Abner
doi : 10.1093/brain/awac035
A calcium-sensitive antibody isolates soluble amyloid-β aggregates and fibrils from Alzheimer’s disease brain
Andrew M Stern, Lei Liu, Shanxue Jin, Wen Liu, Angela L Meunier, Maria Ericsson, Michael B Miller, Megan Batson, Tingwan Sun, Sagar Kathuria, David Reczek, Laurent Pradier, Dennis J Selkoe
doi : 10.1093/brain/awac023
Sex differences in the genetic architecture of cognitive resilience to Alzheimer’s disease
Jaclyn M Eissman, Logan Dumitrescu, Emily R Mahoney, Alexandra N Smith, Shubhabrata Mukherjee, Michael L Lee, Phoebe Scollard, Seo Eun Choi, William S Bush, Corinne D Engelman, Qiongshi Lu, David W Fardo, Emily H Trittschuh, Jesse Mez, Catherine C Kaczorowski, Hector Hernandez Saucedo, Keith F Widaman, Rachel F Buckley, Michael J Properzi, Elizabeth C Mormino, Hyun Sik Yang, Theresa M Harrison, Trey Hedden, Kwangsik Nho, Shea J Andrews, Douglas Tommet, Niran Hadad, R Elizabeth Sanders, Douglas M Ruderfer, Katherine A Gifford, Xiaoyuan Zhong, Neha S Raghavan, Badri N Vardarajan, The Alzheimer’s Disease Neuroimaging Initiative (ADNI), Alzheimer’s Disease Genetics Consortium (ADGC), A4 Study Team, Margaret A Pericak-Vance, Lindsay A Farrer, Li San Wang, Carlos Cruchaga, Gerard D Schellenberg, Nancy J Cox, Jonathan L Haines, C Dirk Keene, Andrew J Saykin, Eric B Larson, Reisa A Sperling, Richard Mayeux, Michael L Cuccaro, David A Bennett, Julie A Schneider, Paul K Crane, Angela L Jefferson, Timothy J Hohman
doi : 10.1093/brain/awac177
Neurovascular injury with complement activation and inflammation in COVID-19
Myoung Hwa Lee, Daniel P Perl, Joseph Steiner, Nicholas Pasternack, Wenxue Li, Dragan Maric, Farinaz Safavi, Iren Horkayne-Szakaly, Robert Jones, Michelle N Stram, Joel T Moncur, Marco Hefti, Rebecca D Folkerth, Avindra Nath
doi : 10.1093/brain/awac151
Functional variant rs2270363 on 16p13.3 confers schizophrenia risk by regulating NMRAL1
Junyang Wang, Shiwu Li, Xiaoyan Li, Jiewei Liu, Jinfeng Yang, Yifan Li, Wenqiang Li, Yongfeng Yang, Jiao Li, Rui Chen, Kaiqin Li, Di Huang, Yixing Liu, Luxian Lv, Ming Li, Xiao Xiao, Xiong Jian Luo
doi : 10.1093/brain/awac020
Medullary kappa-opioid receptor neurons inhibit pain and itch through a descending circuit
Eileen Nguyen, Kelly M Smith, Nathan Cramer, Ruby A Holland, Isabel H Bleimeister, Krystal Flores-Felix, Hanna Silberberg, Asaf Keller, Claire E Le Pichon, Sarah E Ross
doi : 10.1093/brain/awac189
ZBTB11 dysfunction: spectrum of brain abnormalities, biochemical signature and cellular consequences
Dulika Sumathipala, Petter Strømme, Zohreh Fattahi, Torben Lüders, Ying Sheng, Kimia Kahrizi, Ingunn Holm Einarsen, Jennifer L Sloan, Hossein Najmabadi, Lambert van den Heuvel, Ron A Wevers, Sergio Guerrero-Castillo, Lars Mørkrid, Vassili Valayannopoulos, Paul Hoff Backe, Charles P Venditti, Clara D van Karnebeek, Hilde Nilsen, Eirik Frengen, Doriana Misceo
doi : 10.1093/brain/awac034
