Neurology




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سفارش

Spotlight on the April 20 Issue

José G. Merino

doi : 10.1212/WNL.0000000000011794

April 20, 2021; 96 (16) 

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The Phial of Galadriel

Radoslav Raychev, Warren D. Lo

doi : 10.1212/WNL.0000000000011824

April 20, 2021; 96 (16) 

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Seeing the Finish Line Can Baseline OCT Values Predict Long-term Disability and Therapeutic Management in Multiple Sclerosis?

Pablo Villoslada,Steven L. Galetta, Ahmed Toosy

doi : 10.1212/WNL.0000000000011793

April 20, 2021; 96 (16) 

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The Role of Immune Checkpoint Therapy in Propagating Neurologic Immune-Related Adverse Events

Tova Gardin, Erin E. Longbrake

doi : 10.1212/WNL.0000000000011812

April 20, 2021; 96 (16) 

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Temporal Trends in Case Fatality, Discharge Destination, and Admission to Long-term Care After Acute Stroke

Raed A. Joundi, Eric E. Smith,Amy Y.X. Yu, Mohammed Rashid, Jiming Fang,Moira K. Kapral

doi : 10.1212/WNL.0000000000011791

April 20, 2021; 96 (16) 

Objective To determine contemporary trends in case fatality, discharge destination, and admission to long-term care after acute ischemic stroke and intracerebral hemorrhage (ICH) using a large, population-based cohort.

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Detection of Cerebral Microbleeds With Venous Connection at 7-Tesla MRI

Johanna Rotta, Valentina Perosa, Renat Yakupov,Hugo J. Kuijf,Frank Schreiber, Laura Dobisch, Jan Oltmer, Anne Assmann, Oliver Speck, Hans-Jochen Heinze,Julio Acosta-Cabronero, Emrah Duzel, Stefanie Schreiber

doi : 10.1212/WNL.0000000000011790

April 20, 2021; 96 (16) 

Objective Cerebral microbleeds (MBs) are a common finding in patients with cerebral small vessel disease (CSVD) and Alzheimer disease as well as in healthy elderly people, but their pathophysiology remains unclear. To investigate a possible role of veins in the development of MBs, we performed an exploratory study, assessing in vivo presence of MBs with a direct connection to a vein.

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Association of Spectral-Domain OCT With Long-term Disability Worsening in Multiple Sclerosis

Jeffrey Lambe,Kathryn C. Fitzgerald,Olwen C. Murphy,Angeliki G. Filippatou,Elias S. Sotirchos,Grigorios Kalaitzidis,Elena Vasileiou, Nicole Pellegrini, Esther Ogbuokiri, Brandon Toliver, Nicholas J. Luciano, Simidele Davis, Nicholas Fioravante, Ohemaa Kwakyi, Hunter Risher, Ciprian M. Crainiceanu,Jerry L. Prince, Scott D. Newsome,Ellen M. Mowry,Shiv Saidha,Peter A. Calabresi

doi : 10.1212/WNL.0000000000011788

April 20, 2021; 96 (16) 

Objective To evaluate whether a retinal spectral-domain optical coherence tomography (SD-OCT) assessment at baseline is associated with long-term disability worsening in people with multiple sclerosis (PwMS), we performed SD-OCT and Expanded Disability Status Scale (EDSS) assessments among 132 PwMS at baseline and at a median of 10 years later.

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Evaluation of the Diagnostic Criteria for Anti-NMDA Receptor Encephalitis in Japanese Children

Hiroya Nishida, Kuniko Kohyama, Satoko Kumada, Jun-ichi Takanashi, Akihisa Okumura, Asako Horino, Kengo Moriyama, Hiroshi Sakuma

doi : 10.1212/WNL.0000000000011789

April 20, 2021; 96 (16) 

Objective To evaluate the validity of the 2016 clinical diagnostic criteria proposed for probable anti-NMDA receptor (NMDAR) encephalitis in children, we tested the criteria in a Japanese pediatric cohort.

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Expanding the Spectrum of Chronic Immune Sensory Polyradiculopathy

Shahar Shelly, Kamal Shouman, Pritikanta Paul, JaNean Engelstad, Kimberly K. Amrami, Robert J. Spinner, Divyanshu Dubey,  Rocio Vazquez Do Campo, Peter J. Dyck, Christopher J. Klein, P. James B. Dyck

doi : 10.1212/WNL.0000000000011792

April 20, 2021; 96 (16) 

Objective Sensory loss with normal nerve conduction studies (NCS) from focal sensory root inflammatory demyelination is characteristic of chronic immune sensory polyradiculopathy (CISP). However, nonpure cases involving motor and distal sensory nerves exist (CISP-plus). We hypothesize that CISP-plus and CISP are fundamentally part of the same syndrome through comparison of clinical, neurophysiologic, and pathologic features.

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Association of Cortical Hyperexcitability and Cognitive Impairment in Patients With Amyotrophic Lateral Sclerosis

Mana Higashihara, Nathan Pavey,Mehdi van den Bos, Parvathi Menon, Matthew C. Kiernan, Steve Vucic

doi : 10.1212/WNL.0000000000011798

April 20, 2021; 96 (16) 

Objective To determine whether cortical hyperexcitability was more prominent in cognitively impaired patients with amyotrophic lateral sclerosis (ALS).

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Lumbosacral Radiculoplexus Neuropathy

Marcus V. Pinto, Peng-Soon Ng, Benjamin M. Howe, Ruple S. Laughlin, Prabin Thapa, Peter J. Dyck, P. James B. Dyck

doi : 10.1212/WNL.0000000000011799

April 20, 2021; 96 (16) 

Objective To determine whether patients in the community with lumbosacral radiculoplexus neuropathy (LRPN) have milder neuropathy than referral patients, we characterized the outcomes and survival of population-based compared to referral-based LRPN cohorts.

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Impact of Coronavirus Disease 2019 in a French Cohort of Myasthenia Gravis

Guilhem Solé, Stéphane Mathis, Diane Friedman,Emmanuelle Salort-Campana, Céline Tard, Françoise Bouhour, Armelle Magot, Djillali Annane, Bernard Clair, Gwendal Le Masson, Antoine Soulages, Fanny Duval, Louis Carla, Marie-Hélène Violleau, Tiphaine Saulnier, Sandrine Segovia-Kueny, Léa Kern, Jean-Christophe Antoine, Guillemette Beaudonnet, Frédérique Audic, Laurent Kremer, Jean-Baptiste Chanson, Aleksandra Nadaj-Pakleza, Tanya Stojkovic, Pascal Cintas, Marco Spinazzi, Alexandra Foubert-Samier,Shahram Attarian

doi : 10.1212/WNL.0000000000011669

April 20, 2021; 96 (16) 

Objective To describe the clinical characteristics and outcomes of coronavirus disease 2019 (COVID-19) among patients with myasthenia gravis (MG) and identify factors associated with COVID-19 severity in patients with MG.

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Perivascular Spaces in the Basal Ganglia and Long-term Motor Prognosis in Newly Diagnosed Parkinson Disease

Seok Jong Chung, Han Soo Yoo, Na-Young Shin, Yae Won Park, Hye Sun Lee, Ji-Man Hong,Yun Joong Kim, Seung-Koo Lee, Phil Hyu Lee, Young H. Sohn

doi : 10.1212/WNL.0000000000011797

April 20, 2021; 96 (16) 

Objective To investigate the association between enlarged perivascular spaces (PVS) in the basal ganglia (BG-PVS) and long-term motor outcomes in Parkinson disease (PD).

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Five-Year Trends in Payments for Neurologist-Prescribed Drugs in Medicare Part D

Adam de Havenon, Alen Delic, Sarah Dehoney, Presley Whetman, Nazanin Sheibani, Brian Callaghan, John Ney, Gregory J. Esper, Brandon Magliocco, Kavita V. Nair

doi : 10.1212/WNL.0000000000011712

April 20, 2021; 96 (16) 

Objective To determine whether there was an increase in payments for neurologist-prescribed drugs, we performed a retrospective analysis of prescription claims in the Medicare Part D Prescriber Public Use Files from 2013 to 2017.

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What's Happening in Neurology® Clinical Practice

doi : 10.1212/WNL.0000000000011800

April 20, 2021; 96 (16) 

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What's Happening in Neurology® Genetics

doi : 10.1212/WNL.0000000000011806

April 20, 2021; 96 (16) 

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What's Happening in Neurology® Neuroimmunology & Neuroinflammation

doi : 10.1212/WNL.0000000000011801

April 20, 2021; 96 (16) 

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What Is the Clinical Correlation of Cardiac Noradrenergic Denervation in Parkinson Disease?

Guillaume Lamotte, Eduardo E. Benarroch

doi : 10.1212/WNL.0000000000011805

April 20, 2021; 96 (16) 

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Neurologic Adverse Events of Immune Checkpoint Inhibitors

Alessandro Marini, Andrea Bernardini, Gian Luigi Gigli, Mariarosaria Valente,Sergio Mu?iz-Castrillo, Jérôme Honnorat, Alberto Vogrig

doi : 10.1212/WNL.0000000000011795

April 20, 2021; 96 (16) 

Objective To define the clinical characteristics, management, and outcome of neurologic immune-related adverse events (n-irAEs) of immune checkpoint inhibitors (ICIs).

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Multiple Sclerosis Relapse Presenting as Sensorineural Hearing Loss

Parth Bansal, Birinder S. Paul, Gagandeep Singh

doi : 10.1212/WNL.0000000000011796

April 20, 2021; 96 (16) 

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Teaching NeuroImages: Glossopharyngeal Nerve Focal Pressure Atrophy in Glossopharyngeal Neuralgia

Luying Li, Heng Zhang

doi : 10.1212/WNL.0000000000011321

April 20, 2021; 96 (16) 

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Journal Club: Diffusion-Weighted MRI in Transient Global Amnesia and Its Diagnostic Implications

Daniel Talmasov, Arjun V. Masurkar

doi : 10.1212/WNL.0000000000011352

April 20, 2021; 96 (16) 

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Pearls & Oy-sters: Primary CNS Burkitt Lymphoma in Pregnancy

Angel Miraclin, Ajith Sivadasan, S. Rima, Pavithra Mannam, Ankush Gupta, Anup J. Devasia, A.T. Prabhakar, Vivek Mathew

doi : 10.1212/WNL.0000000000011495

April 20, 2021; 96 (16) 

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Teaching Video Neuroimages: Spontaneous Nystagmus Reversal in Acute Attack of Ménière Disease

Anand K. Bery, Tzu-Pu Chang

doi : 10.1212/WNL.0000000000011053

April 20, 2021; 96 (16) 

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Editors' Note: Clinical Characterization of Delayed Alcohol-Induced Headache: A Study of 1,108 Participants

Ariane Lewis, Steven Galetta

doi : 10.1212/WNL.0000000000011804

April 20, 2021; 96 (16) 

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Reader Response: Clinical Characterization of Delayed Alcohol-Induced Headache: A Study of 1,108 Participants

Vinod K. Gupta

doi : 10.1212/WNL.0000000000011802

April 20, 2021; 96 (16) 

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Author Response: Clinical Characterization of Delayed Alcohol-Induced Headache: A Study of 1,108 Participants

David Garc?a-Azor?n, Henrik W. Schytz, ?ngel L. Guerrero

doi : 10.1212/WNL.0000000000011803

April 20, 2021; 96 (16) 

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Reader Response: Clinical Characterization of Delayed Alcohol-Induced Headache: A Study of 1,108 Participants

Peter J. Goadsby

doi : 10.1212/WNL.0000000000011807

April 20, 2021; 96 (16) 

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Author Response: Clinical Characterization of Delayed Alcohol-Induced Headache: A Study of 1,108 Participants

David Garc?a-Azor?n, ?ngel L. Guerrero

doi : 10.1212/WNL.0000000000011809

April 20, 2021; 96 (16) 

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Reader Response: Clinical Characterization of Delayed Alcohol-Induced Headache: A Study of 1,108 Participants

Jonathan H. Smith

doi : 10.1212/WNL.0000000000011808

April 20, 2021; 96 (16) 

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Author Response: Clinical Characterization of Delayed Alcohol-Induced Headache: A Study of 1,108 Participants

David Garc?a-Azor?n, ?ngel L. Guerrero

doi : 10.1212/WNL.0000000000011810

April 20, 2021; 96 (16) 

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