Michael A. Incze, M.D., M.S.Ed.
doi : 10.1056/NEJMp2032066
N Engl J Med 2021; 384:297-299
Mark J. Kissler, M.D., Katherine Kissler, M.S., and Marisha Burden, M.D.
doi : 10.1056/NEJMp2027190
N Engl J Med 2021; 384:299-301
Heather Carmichael, M.D.
doi : 10.1056/NEJMp2029239
N Engl J Med 2021; 384:302-303
Jason G. Andrade, M.D., George A. Wells, Ph.D., Marc W. Deyell, M.D., Matthew Bennett, M.D., Vidal Essebag, M.D., Ph.D., Jean Champagne, M.D., Jean-Francois Roux, M.D., Derek Yung, M.D., Allan Skanes, M.D., Yaariv Khaykin, M.D., Carlos Morillo, M.D., Umjeet Jolly, M.D.,
doi : 10.1056/NEJMoa2029980
N Engl J Med 2021; 384:305-315
Guidelines recommend a trial of one or more antiarrhythmic drugs before catheter ablation is considered in patients with atrial fibrillation. However, first-line ablation may be more effective in maintaining sinus rhythm.
Oussama M. Wazni, M.D., Gopi Dandamudi, M.D., Nitesh Sood, M.D., Robert Hoyt, M.D., Jaret Tyler, M.D., Sarfraz Durrani, M.D., Mark Niebauer, M.D., Kevin Makati, M.D., Blair Halperin, M.D., Andre Gauri, M.D., Gustavo Morales, M.D., Mingyuan Shao, Ph.D.,
doi : 10.1056/NEJMoa2029554
N Engl J Med 2021; 384:316-324
In patients with symptomatic paroxysmal atrial fibrillation that has not responded to medication, catheter ablation is more effective than antiarrhythmic drug therapy for maintaining sinus rhythm. However, the safety and efficacy of cryoballoon ablation as initial first-line therapy have not been established.
Aaron Waxman, M.D., Ph.D., Ricardo Restrepo-Jaramillo, M.D., Thenappan Thenappan, M.D., Ashwin Ravichandran, M.D., Peter Engel, M.D., Abubakr Bajwa, M.D., Roblee Allen, M.D., Jeremy Feldman, M.D., Rahul Argula, M.D., Peter Smith, Pharm.D., Kristan Rollins, Pharm.D., Chunqin Deng, M.D., Ph.D.,
doi : 10.1056/NEJMoa2008470
N Engl J Med 2021; 384:325-334
No therapies are currently approved for the treatment of pulmonary hypertension in patients with interstitial lung disease. The safety and efficacy of inhaled treprostinil for patients with this condition are unclear.
David K. Turok, M.D., Alexandra Gero, M.P.H., Rebecca G. Simmons, Ph.D., Jennifer E. Kaiser, M.D., Gregory J. Stoddard, M.P.H., Corinne D. Sexsmith, M.S., Lori M. Gawron, M.D., and Jessica N. Sanders, Ph.D.
doi : 10.1056/NEJMoa2022141
N Engl J Med 2021; 384:335-344
In the United States, more intrauterine device (IUD) users select levonorgestrel IUDs than copper IUDs for long-term contraception. Currently, clinicians offer only copper IUDs for emergency contraception because data are lacking on the efficacy of the levonorgestrel IUD for this purpose.
Sonny Dhanani, M.D., Laura Hornby, M.Sc., Amanda van Beinum, M.Sc., Nathan B. Scales, Ph.D., Melanie Hogue, M.Sc., Andrew Baker, M.D., Stephen Beed, M.D., J. Gordon Boyd, M.D., Ph.D., Jennifer A. Chandler, L.L.B., L.L.M., Michaël Chassé, M.D., Ph.D., Frederick D’Aragon, M.D., Ph.D., Cameron Dezfulian, M.D.,
doi : 10.1056/NEJMoa2022713
N Engl J Med 2021; 384:345-352
The minimum duration of pulselessness required before organ donation after circulatory determination of death has not been well studied.
Gregory F. Michaud, M.D., and William G. Stevenson, M.D.
doi : 10.1056/NEJMcp2023658
N Engl J Med 2021; 384:353-361
David Burke, M.D.
doi : 10.1056/NEJMicm2005527
N Engl J Med 2021; 384:362
Moran S. Gal, M.D., and Shoshana Greenberger, M.D., Ph.D.
doi : 10.1056/NEJMicm2022429
N Engl J Med 2021; 384:e8
Sebastian H. Unizony, M.D., Hillary R. Kelly, M.D., Elizabeth K. O’Donnell, M.D., and Sam Sadigh, M.D.
doi : 10.1056/NEJMcpc2002416
N Engl J Med 2021; 384:363-372
Joseph E. Marine, M.D.
doi : 10.1056/NEJMe2033534
N Engl J Med 2021; 384:374-375
Darren B. Taichman, M.D., Ph.D.
doi : 10.1056/NEJMe2033181
N Engl J Med 2021; 384:376-377
Eric J. Rubin, M.D., Ph.D., Lindsey R. Baden, M.D., Anthony S. Fauci, M.D., and Stephen Morrissey, Ph.D.
doi : 10.1056/NEJMe2101618
N Engl J Med 2021; 384:e22
Scott S. Zamvil, M.D., Ph.D., and Stephen L. Hauser, M.D.
doi : 10.1056/NEJMcibr2032177
N Engl J Med 2021; 384:378-381
doi : 10.1056/NEJMc2029834
N Engl J Med 2021; 384:382-383
doi : 10.1056/NEJMc2032809
N Engl J Med 2021; 384:388-390
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