Jemima Albayda, Christopher Mecoli, Livia Casciola?Rosen, Sonye K. Danoff, Cheng Ting Lin, David Hines, Laura Gutierrez?Alamillo, Julie J. Paik, Eleni Tiniakou, Andrew L. Mammen, Lisa Christopher?Stine
doi : 10.1002/acr2.11247
ACR Open Rheumatol. 2021 May; 3(5): 287–294
Antibodies against the small ubiquitin?like modifier (SUMO) activating enzyme (SAE) are one of the rarer specificities associated with dermatomyositis (DM). The purpose of this study is to describe the clinical characteristics of patients with anti?SAE autoantibodies in a North American cohort and to ascertain cancer prevalence. We also describe the performance characteristics of the line blotting (Euroimmun) method for antibody detection compared with an immunoprecipitation?based assay.
Claire E. H. Barber, Nicole Spencer, Nick Bansback, Gabrielle L. Zimmermann, Linda C. Li, Dawn P. Richards, Laurie Proulx, Dianne P. Mosher, Glen S. Hazlewood
doi : 10.1002/acr2.11250
ACR Open Rheumatol. 2021 May; 3(5): 312–323
Decision aids are being developed to support guideline?based rheumatology care in Canada. The study objective was to identify barriers to decision aid use in rheumatoid arthritis (RA) within a behavior change model to inform an implementation strategy.
Xiaoxiao Liu, Claire E. H. Barber, Steven Katz, Joanne Homik, Stefania Bertazzon, Alka B. Patel, Jill Robert, Christopher Smith, Dianne Mosher, Deborah A. Marshall
doi : 10.1002/acr2.11251
ACR Open Rheumatol. 2021 May; 3(5): 324–332
Timely access to rheumatologists remains a challenge in Alberta, a Canadian province with vast rural areas, whereas rheumatologists are primarily clustered in metro areas. To address the goal of timely and equitable access to rheumatoid arthritis (RA) care, health planners require information at the regional and local level to determine the RA prevalence and the associated health care needs.
Ruth K. Topless, Amanda Phipps?Green, Megan Leask, Nicola Dalbeth, Lisa K. Stamp, Philip C. Robinson, Tony R. Merriman
doi : 10.1002/acr2.11252
ACR Open Rheumatol. 2021 May; 3(5): 333–340
The objectives for this study were to assess whether gout and/or rheumatoid arthritis (RA) are risk factors for coronavirus disease 2019 (COVID?19) diagnosis and to assess whether gout and/or RA are risk factors for death from COVID?19.
Daniel H. Solomon, Joel S. Weissman, Hyon Choi, Steven J. Atlas, Cesar Berardinelli, Julien Dedier, Michael A. Fischer, John Fitzgerald, Erica Hinteregger, Brianne Johnsen, Diana D. Marini, Robert McLean, Fred Murray, Tuhina Neogi, Lynn B. Oertel, Michael H. Pillinger, Kevin R. Riggs, Ken Saag, Dong Suh, James Watkins, Michael J. Barry
doi : 10.1002/acr2.11243
ACR Open Rheumatol. 2021 May; 3(5): 341–348
Disagreement exists between rheumatology and primary care societies regarding gout management. This paper describes a formal process for gathering input from stakeholders in the planning of a trial to compare gout management strategies.
Flavia V. Castelino, Teng Moua
doi : 10.1002/acr2.11253
ACR Open Rheumatol. 2021 May; 3(5): 295–304
Interstitial lung disease (ILD) is a common manifestation of connective tissue diseases (CTDs). A proportion of patients with CTD?ILDs develop progressive fibrosing ILD, which is characterized by worsening fibrotic abnormalities on high?resolution computed tomography scan, decline in lung function, worsening symptoms, and early mortality. Here, we review the impact of ILD in patients with CTDs, the importance of prompt diagnosis and close monitoring, and the evidence available to guide the management of CTD?ILDs. Management of patients with CTD?ILDs should be individualized and involve close collaboration between rheumatologists and pulmonologists. Immunosuppression is the mainstay of therapy for CTDs, but evidence for its effectiveness in slowing the progression of ILD is limited. Recently, nintedanib has been approved to slow decline in lung function in patients with systemic sclerosis–associated ILD and chronic fibrosing ILDs with a progressive phenotype. The results of ongoing clinical trials will help clinicians take a more evidence?based approach to the treatment of CTD?ILDs.
Kreager A. Taber, Jessica N. Williams, Weixing Huang, Katherine McLaughlin, Christine Vogeli, Rebecca Cunningham, Lisa Wichmann, Candace H. Feldman
doi : 10.1002/acr2.11236
ACR Open Rheumatol. 2021 May; 3(5): 305–311
We studied patients with systemic lupus erythematosus (SLE) enrolled in a nurse?led, multihospital, primary care–based integrated care management program (iCMP) for complex patients with chronic conditions to understand whether social determinants of health (SDoH), including food insecurity, housing instability, and financial constraints, were prevalent in this population.
Jessica Neely, Julia Shalen, Hugh Sturrock, Susan Kim, for the Childhood Arthritis and Rheumatology Research Alliance Investigators
doi : 10.1002/acr2.11246
ACR Open Rheumatol. 2021 May; 3(5): 349–354
To determine factors associated with diagnostic delays and outcomes in juvenile dermatomyositis (JDM) in the Childhood Arthritis and Rheumatology Research Alliance Legacy Registry (CLR).
Zhiyong Chen, Hua Zhang, Sheng?Ming Dai
doi : 10.1002/acr2.11257
ACR Open Rheumatol. 2021 May; 3(5): 355
Victoria L Johnson, Jon Ryan, Ivan Ho?Shon, Trent Davidson, Anthony Sammel
doi : 10.1002/acr2.11249
ACR Open Rheumatol. 2021 May; 3(5): 356
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