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In Memoriam: Alexander W. Dromerick Jr, MD, July 1, 1958-August 21, 2021.
Savitz, Sean I. MD; Newport, Elissa L. PhD; Edwards, Dorothy PhD
doi : 10.1161/STROKEAHA.122.039909
Volume 53(12) pgs. 3525-3789,e496-e533 December 2022
Intensive Social Interaction for Treatment of Poststroke Depression in Subacute Aphasia: The CONNECT Trial.
Stahl, Benjamin PhD ,,,*; Millrose, Saskia MSc ,,*; Denzler, Petra MSc; Lucchese, Guglielmo MD, PhD; Jacobi, Frank PhD; Floel, Agnes MD
doi : 10.1161/STROKEAHA.122.039995
AB Background: Limiting the ability to engage in social interaction, aphasia increases the risk of poststroke depression and may prevent classical forms of psychotherapy. Our parallel-group, blinded-assessment, quasi-randomized controlled trial explores the feasibility and potential efficacy of intensive social interaction as a means to alleviate poststroke depression in subacute aphasia. Methods: We adopted a linguistically validated treatment program based on massed practice and conversational turn-taking (Intensive Language-Action Therapy).
Telehealth After Stroke Care Pilot Randomized Trial of Home Blood Pressure Telemonitoring in an Underserved Setting.
Naqvi, Imama A. MD; Strobino, Kevin MS; Kuen Cheung, Ying PhD; Li, Hanlin PharmD; Schmitt, Kevin MS; Ferrara, Stephen DNP; Tom, Sarah E. PhD; Arcia, Adriana PhD; Williams, Olajide A. MD, MS; Kronish, Ian M. MD, MPH; Elkind, Mitchell S.V. MD, MS
doi : 10.1161/STROKEAHA.122.041020
AB Background: Hypertension is the most important modifiable stroke risk factor, but blood pressure (BP) remains poorly controlled after stroke, especially among Black and Hispanic patients. We tested the feasibility of TASC (Telehealth After Stroke Care), a post-acute stroke care model integrating nurse-supported home BP telemonitoring, tailored infographics, and multidisciplinary team video visits. Methods: Acute stroke patients with hypertension were randomized at discharge to usual care or usual care with TASC.
Comparison of Three Scores of Collateral Status for Their Association With Clinical Outcome: The HERMES Collaboration.
Gensicke, Henrik MD ,,*; Al-Ajlan, Fahad MD ,*; Fladt, Joachim MD ,,*; Campbell, Bruce C.V. MD, PhD; Majoie, Charles B.L.M. MD, PhD; Bracard, Serge MD, PhD; Hill, Michael D. MD, MSc; Muir, Keith W. MD; Demchuk, Andrew MD; San Roman, Luis MD; van der Lugt, Aad MD, PhD; Liebeskind, David S. MD; Brown, Scott PhD; White, Philip M. MD; Guillemin, Francis MD, PhD; Davalos, Antoni MD, PhD; Jovin, Tudor G. MD; Saver, Jeffrey L. MD; Dippel, Diederik W.J. MD, PhD; Goyal, Mayank MD, PhD; Mitchell, Peter J. MD; Menon, Bijoy K. MD, MSc; for the HERMES Collaborators
doi : 10.1161/STROKEAHA.122.039717
Leptomeningeal collateral status on baseline computed tomographic angiography (CTA) is associated with clinical outcome after acute ischemic stroke treatment. However, assessment of collateral status is not uniform. To compare 3 different CTA collateral scores (CS) and imaging techniques about their association with clinical outcome.
Intravenous Thrombolysis in Patients With Ischemic Stroke Aged >=90 Years: A Cohort Study From the TRISP Collaboration.
Altersberger, Valerian L. MD ,*; Rusche, Norman MD ,,*; Martinez-Majander, Nicolas MD; Hametner, Christian MD; Scheitz, Jan F. MD; Henon, Hilde MD, PhD; Dell'Acqua, Maria Luisa MD; Strambo, Davide MD; Stolp, Jeffrey MD; Heldner, Mirjam R. MD; Grisendi, Ilaria MD; Jovanovic, Dejana R. MD, PhD; Bejot, Yannick MD, PhD; Pezzini, Alessandro MD; Leker, Ronen R. MD; Kagi, Georg MD; Wegener, Susanne MD; Cereda, Carlo W. MD; Lindgren, Erik MD; Ntaios, George PhD; Piot, Ines MD; Polymeris, Alexandros A. MD; Lyrer, Philippe A. MD; Raty, Silja MD; Sibolt, Gerli MD, PhD; Tiainen, Marjaana MD, PhD; Heyse, Miriam MD; Erdur, Hebun MD; Kaaouana, Olfa MD; Padjen, Visnja PhD; Zedde, Marialuisa MD; Arnold, Marcel MD; Nederkoorn, Paul J. MD, PhD; Michel, Patrik MD; Bigliardi, Guido MD; Zini, Andrea MD; Cordonnier, Charlotte PhD; Nolte, Christian H. MD; Ringleb, Peter A. MD; Curtze, Sami PhD; Engelter, Stefan T. MD; Gensicke, Henrik MD; for the Thrombolysis in Stroke Patients (TRISP) Collaborators
doi : 10.1161/STROKEAHA.122.039426
The probability to receive intravenous thrombolysis (IVT) for treatment of acute ischemic stroke declines with increasing age and is consequently the lowest in very elderly patients. Safety concerns likely influence individual IVT treatment decisions.
Significance of Baseline Ischemic Core Volume on Stroke Outcome After Endovascular Therapy in Patients Age >=75 Years: A Pooled Analysis of Individual Patient Data From 7 Trials.
Tanaka, Koji MD; Goyal, Mayank MD; Menon, Bijoy K. MD; Campbell, Bruce C.V. PhD; Mitchell, Peter J. MD; Jovin, Tudor G. MD; Davalos, Antoni MD, PhD; Jansen, Olav PhD; Muir, Keith W. MD; White, Phil M. MD; Bracard, Serge MD; Achit, Hamza PhD; Dippel, Diederik W.J. MD; Majoie, Charles B.L.M. MD; Hill, Michael D. MD; Brown, Scott PhD; Demchuk, Andrew M. MD; on behalf of the HERMES Collaborators
doi : 10.1161/STROKEAHA.122.039774
Age and infarct volume are strong predictors of outcome in patients with ischemic stroke who underwent endovascular therapy (EVT). We aimed to investigate the impact of ischemic core volume (ICV) on stroke outcome after EVT in elderly.
Direct, Indirect, and Combined Extracranial-to-Intracranial Bypass for Adult Moyamoya Disease: An Updated Systematic Review and Meta-Analysis.
Nguyen, Vincent N. MD; Motiwala, Mustafa MD; Elarjani, Turki MD; Moore, Kenneth A. MD; Miller, L. Erin BA; Barats, Michael MS; Goyal, Nitin MD; Elijovich, Lucas MD; Klimo, Paul MD, MPH; Hoit, Daniel A. MD, MPH; Arthur, Adam S. MD, MPH; Morcos, Jacques J. MD; Khan, Nickalus R. MD
doi : 10.1161/STROKEAHA.122.039584
Moyamoya disease is a chronic, progressive cerebrovascular disease involving occlusion or stenosis of the terminal portion of the internal carotid artery. We conducted an updated systematic review and meta-analysis to investigate clinical and angiographic outcomes comparing direct, combined, and indirect bypass for the treatment of moyamoya disease in adults.
Prospective Observational Cohort Study of Tenecteplase Versus Alteplase in Routine Clinical Practice.
Warach, Steven J. MD, PhD; Dula, Adrienne N. PhD; Milling, Truman J. MD; Miller, Samantha MD; Allen, Leigh RN, MSN; Zuck, Nathan D. BS; Miller, Collin MS; Jesser, Christine A. ScD; Misra, Lotika R. MD; Miley, Jefferson T. MD; Mawla, Manzure DO; Ding, Ming-Chieh MD, PhD; Bertelson, John A. MD; Tsui, Annie Y. DO; Jefferson, John R. MD; Davison, Holly M. PA-C; Shah, Darshan N. MD; Ellington, Kent T. MD; Padrick, Matthew M. MD; Nova, Alan S. DO; Krishna, Vivek R. MD; Davis, Lisa A. RN, MSN; Paydarfar, David MD
doi : 10.1161/STROKEAHA.122.038950
A 10-hospital regional network transitioned to tenecteplase as the standard of care stroke thrombolytic in September 2019 because of potential workflow advantages and reported noninferior clinical outcomes relative to alteplase in meta-analyses of randomized trials.
Reperfusion Without Functional Independence in Late Presentation of Stroke With Large Vessel Occlusion.
Seker, Fatih MD; Qureshi, Muhammad M. MBBS, MPH; Mohlenbruch, Markus A. MD; Nogueira, Raul G. MD; Abdalkader, Mohamad MD; Ribo, Marc MD; PhD; Caparros, Francois MD; Haussen, Diogo C. MD; Mohammaden, Mahmoud H. MD; Sheth, Sunil A. MD; Ortega-Gutierrez, Santiago MD; Siegler, James E. MD; Zaidi, Syed F. MD; Olive-Gadea, Marta MD; Henon, Hilde MD, PhD; Castonguay, Alicia C. PhD; Nannoni, Stefania MD; Kaesmacher, Johannes MD; Puri, Ajit S. MD; Farooqui, Mudassir MD; Salazar-Marioni, Sergio MD; Kuhn, Anna L. MD, PhD; Kiley, Nicole L. PA-C; Farzin, Behzad MD; Boisseau, William MD; Masoud, Hesham E. MD; Lopez, Carlos Ynigo MD; Rana, Ameena MD; Abdul Kareem, Samer MD; Sathya, Anvitha BA; Klein, Piers MA; Kassem, Mohammad W. MD, MBA; Cordonnier, Charlotte MD, PhD; Gralla, Jan MD; Fischer, Urs MD, MSc; Michel, Patrik MD; Strambo, Davide MD; Jovin, Tudor G. MD; Raymond, Jean MD; Zaidat, Osama O. MD, MS; Ringleb, Peter A. MD; Nguyen, Thanh N. MD; Nagel, Simon MD
doi : 10.1161/STROKEAHA.122.039476
Reperfusion without functional independence (RFI) is an undesired outcome following thrombectomy in acute ischemic stroke. The primary objective was to evaluate, in patients presenting with proximal anterior circulation occlusion stroke in the extended time window, whether selection with computed tomography (CT) perfusion or magnetic resonance imaging is associated with RFI, mortality, or symptomatic intracranial hemorrhage (sICH) compared with noncontrast CT selected patients.
Evaluating the Diagnostic Performance of Prehospital Stroke Scales Across the Range of Deficit Severity: Analysis of the Prehospital Triage of Patients With Suspected Stroke Study.
Ganesh, Aravind MD, DPhil ,*; van de Wijdeven, Ruben M. MD ,*; Ospel, Johanna M. MD, PhD; Duvekot, Martijne H.C. MD; Venema, Esmee MD, PhD; Rozeman, Anouk D. MD; Moudrous, Walid MD; Dorresteijn, Kirsten R.I.S. MD; Hensen, Jan-Hein MD, PhD; van Es, Adriaan C.G.M. MD, PhD; van der Lugt, Aad MD, PhD; Kerkhoff, Henk MD, PhD; Dippel, Diederik W.J. MD, PhD; Goyal, Mayank MD, PhD; Roozenbeek, Bob MD, PhD; on behalf of the PRESTO Investigators; Lingsma, Hester F; Vermeij, Frederique H; Lingsma, Hester F; Rozeman, Anouk D; Vermeij, Frederique H; Alblas, Kees C L; Mulder, Laus J M M; Wijnhoud, Annemarie D; Maasland, Lisette; van Eijkelenburg, Roeland P J; Biekart, Marileen; Willeboer, M L; Buijck, Bianca; van Doormaal, Pieter Jan; Bakker, Jeannette; Plaisier, Aarnout; Nijeholt, Geert Lycklama a; Hoek, Amber; Rozeman, Anouk D; Bakker, Jeannette; Oskam, Erick; Vermeij, Frederique H; van der Zon, Mandy M A; Zwets, Egon D; Alblas, Kees C L; Mulder, Laus J M M; Kuiper, Jan Willem; Wijnhoud, Annemarie D; van Moll, Bruno J M; Plaisier, Aarnout; Maasland, Lisette; Woudenberg, Mirjam; van Eijkelenburg, Roeland P J; de Leeuw, Arnoud M; Noordam-Reijm, Anja; Bevelander, Timo; Chalos, Vicky; Wiegers, Eveline J A; Wolff, /Lennard; van Kalkeren, Dennis C; van den Biggelaar, Jochem
doi : 10.1161/STROKEAHA.122.039825
The usefulness of prehospital scales for identifying anterior circulation large vessel occlusion (aLVO) in patients with suspected stroke may vary depending on the severity of their presentation. The performance of these scales across the spectrum of deficit severity is unclear. The aim of this study was to evaluate the diagnostic performance of 8 prehospital scales for identifying aLVO across the spectrum of deficit severity.
Characteristics and Outcomes of Thrombolysis-Treated Stroke Patients With and Without Saccular Intracranial Aneurysms.
Virta, Jyri J. MD, PhD; Strbian, Daniel MD, PhD; Putaala, Jukka MD, PhD; Kaprio, Jaakko MD, PhD; Korja, Miikka MD, PhD
doi : 10.1161/STROKEAHA.122.040151
Intravenous thrombolysis seems safe in acute ischemic stroke patients with saccular, unruptured intracranial aneurysms (UIAs), but little is known about the differences in cardiovascular risk factors and outcomes between intravenous thrombolysis-treated stroke patients with and without UIAs. We hypothesized that UIA patients would have a higher burden of cardiovascular risk factors and, therefore, a higher risk of an unfavorable outcome.
Impact of Renal Function on Short-Term Outcome After Reperfusion Therapy in Patients With Ischemic Stroke.
Park, Hyungjong MD; Kim, Young Dae MD, PhD; Nam, Hyo Suk MD, PhD; Yoo, Joonsang MD; Sohn, Sung-Il MD, PhD; Hong, Jeong-Ho MD, PhD; Kim, Byung Moon MD, PhD; Kim, Dong Joon MD, PhD; Bang, Oh Young MD, PhD; Seo, Woo-Keun MD, PhD; Chung, Jong-Won MD, PhD; Lee, Kyung-Yul MD, PhD; Jung, Yo Han MD, PhD; Lee, Hye Sun PhD; Ahn, Seong Hwan MD, PhD; Shin, Dong Hoon MD, PhD; Choi, Hye-Yeon MD, PhD; Cho, Han-Jin MD, PhD; Baek, Jang-Hyun MD; Kim, Gyu Sik MD, PhD; Seo, Kwon-Duk MD; Kim, Seo Hyun MD, PhD; Song, Tae-Jin MD, PhD; Kim, Jinkwon MD, PhD; Han, Sang Won MD; Park, Joong Hyun MD, PhD; Lee, Suk Ik MD, PhD; Heo, Joon Nyung MD; Lee, Hyung Woo MD; Lee, Il Hyung MD; Baik, Minyoul MD; Heo, Ji Hoe MD, PhD; on behalf of the SECRET Study Investigators
doi : 10.1161/STROKEAHA.122.039129
A high and low estimated glomerular filtration rate (eGFR) could affect outcomes after reperfusion therapy for ischemic stroke. This study aimed to determine whether renal function based on eGFR affects mortality risk in patients with ischemic stroke within 6 months following reperfusion therapy.
Prehospital Blood Pressure and Clinical and Radiological Outcomes in Acute Spontaneous Intracerebral Hemorrhage.
Larsen, Kristin Tveitan MD; Selseth, Maiken Nordahl MD; Jahr, Silje Holt MD; Hillestad, Vigdis MD, PhD; Koubaa, Nojoud MD; Sandset, Else Charlotte MD, PhD; Ronning, Ole Morten MD, PhD ,,*; Kristoffersen, Espen Saxhaug MD, PhD ,,*
doi : 10.1161/STROKEAHA.121.038524
High blood pressure (BP) is associated with poor outcome in acute spontaneous intracerebral hemorrhage. Little is known about the predictive value of prehospital BP in intracerebral hemorrhage.
Unraveling Blood Pressure Outcome Relationships: Further Insights From the Prehospital Phase.
Butcher, Ken S. PhD; Anderson, Craig S. PhD
Quantifying Improved Outcomes, Cost Savings, and Hospital Volume Changes From Optimized Emergency Stroke Transport.
Paydarfar, Daniel A. BS; Holodinsky, Jessalyn K. PhD; Abbas, Huda; Field, Thalia S. MD, MHSc; Zhou, Lily W. MD; Kamal, Noreen PhD
doi : 10.1161/STROKEAHA.122.039172
A previously published conditional probability model optimizes prehospital emergency transport protocols for patients with suspected large-vessel occlusion by recommending the transport strategy, drip-and-ship or mothership, that results in a higher probability of an excellent outcome.
Risk Factors for Perioperative Brain Lesions in Infants With Congenital Heart Disease: A European Collaboration.
Bonthrone, Alexandra F. PhD ,*; Stegeman, Raymond MD, PhD ,,*; Feldmann, Maria MD, PhD; Claessens, Nathalie H.P. MD, PhD; Nijman, Maaike MD; Jansen, Nicolaas J.G. MD, PhD; Nijman, Joppe MD, PhD; Groenendaal, Floris MD, PhD; de Vries, Linda S. MD, PhD; Benders, Manon J.N.L. MD, PhD; Haas, Felix MD, PhD; Bekker, Mirielle N. MD, PhD; Logeswaran, Thushiha MD, PhD; Reich, Bettina MD, PhD; Kottke, Raimund MD; Hagmann, Cornelia MD, PhD; Latal, Beatrice MD, MPH; Dave, Hitendu MD; Simpson, John FRCP, MD; Pushparajah, Kuberan FRCP, PhD; Austin, Conal FRCS; Kelly, Christopher J. MRCPCH, PhD; Arulkumaran, Sophie FRCR, PhD; Rutherford, Mary A. FRCR, FRCPCH, MD; Counsell, Serena J. PhD; Knirsch, Walter MD ,+; Breur, Johannes M.P.J. MD, PhD ,+
doi : 10.1161/STROKEAHA.122.039492
Infants with congenital heart disease are at risk of brain injury and impaired neurodevelopment. The aim was to investigate risk factors for perioperative brain lesions in infants with congenital heart disease.
Depression or Anxiety According to Management Modalities in Patients With Unruptured Intracranial Aneurysms.
Lim, Yong Cheol MD, PhD; Lee, Eunyoung PhD; Song, Jihye MD, PhD
doi : 10.1161/STROKEAHA.122.040330
In the treatment of unruptured intracranial aneurysms, the risk was usually estimated by objective neurological sequelae. However, their effects on depression and anxiety are rare and remain controversial.
Fibrinogen Depletion Coagulopathy Predicts Major Bleeding After Thrombolysis for Ischemic Stroke: A Multicenter Study.
Romoli, Michele MD, PhD ,,*; Vandelli, Laura MD ,*; Bigliardi, Guido MD; Naccarato, Marcello MD, PhD; Moller, Jessica MD; Balestrino, Maurizio MD; Giammello, Fabrizio MD; Gentile, Mauro MD; Dell'Acqua, Maria Luisa MD; Manganotti, Paolo MD; Forlivesi, Stefano MD; Melis, Maurizio MD; Picchetto, Livio MD, PhD; Rosafio, Francesca MD; Furlanis, Giovanni MD; Testoni, Stefania MD; Piras, Valeria MD; Malfatto, Laura MD, PhD; Musolino, Rosa Fortunata MD; Scali, Ilario MD; Maffei, Stefania PhD; Migliaccio, Ludovica MSc; Trenti, Tommaso MD; Mancini, Rita ScD; Marietta, Marco MD; Randi, Vanda MD; Meletti, Stefano MD; Zini, Andrea MD
doi : 10.1161/STROKEAHA.122.039652
Symptomatic intracerebral hemorrhage (sICH) and major bleeding can be fatal complications of intravenous thrombolysis (IVT) for acute ischemic stroke. We investigated the impact of early fibrinogen depletion after IVT on major bleeding events.
Clinical Diagnosis of Probable Cerebral Amyloid Angiopathy: Diagnostic Accuracy Meta-Analysis of the Boston Criteria.
Charidimou, Andreas MD, PhD; Boulouis, Gregoire MD, PhD
doi : 10.1161/STROKEAHA.122.039501
The Boston criteria are used widely for the noninvasive diagnosis of sporadic cerebral amyloid angiopathy (CAA) and hence clinical decision-making, as well as research in the field.
Spatial Relation Between White Matter Hyperintensities and Incident Lacunes of Presumed Vascular Origin: A 14-Year Follow-Up Study.
Yi, Fang MD, PhD; Cai, Mengfei MD, PhD; Jacob, Mina A. MD; Marques, Jose PhD; Norris, David G. PhD; Duering, Marco MD; Tuladhar, Anil M. MD, PhD; de Leeuw, Frank-Erik MD, PhD
doi : 10.1161/STROKEAHA.122.039903
The underlying mechanisms of incident lacunes regarding their spatial distribution remain largely unknown. We investigated the spatial distribution pattern and MRI predictors of incident lacunes in relation to white matter hyperintensity (WMH) over 14 years follow-up in sporadic small vessel disease.
Vascular Collagen Type-IV in Hypertension and Cerebral Small Vessel Disease.
Kumar, Apoorva A. BSc; Yeo, Natalie MBBS; Whittaker, Max MBBS; Attra, Priya MBBS; Barrick, Thomas R. PhD; Bridges, Leslie R. FRCPath; Dickson, Dennis W. MD; Esiri, Margaret M. FRCPath; Farris, Chad W. PhD; Graham, Delyth PhD; Lin, Wen Lang PhD; Meijles, Daniel N. PhD; Pereira, Anthony C. FRCP; Perry, Gregory MSc; Rosene, Douglas L. PhD; Shtaya, Anan B. FRCS; Van Agtmael, Tom PhD; Zamboni, Giovanna PhD; Hainsworth, Atticus H. PhD
doi : 10.1161/STROKEAHA.122.037761
Cerebral small vessel disease (SVD) is common in older people and causes lacunar stroke and vascular cognitive impairment. Risk factors include old age, hypertension and variants in the genes COL4A1/COL4A2 encoding collagen alpha-1(IV) and alpha-2(IV), here termed collagen-IV, which are core components of the basement membrane.
Effect of Exercise on Brain-Derived Neurotrophic Factor in Stroke Survivors: A Systematic Review and Meta-Analysis.
Ashcroft, Sarah K. MCEP; Ironside, Daniel D. BExSc Hon; Johnson, Liam PhD; Kuys, Suzanne S. PhD; Thompson-Butel, Angelica G. PhD
doi : 10.1161/STROKEAHA.122.039919
BDNF (brain-derived neurotrophic factor) is a biomarker of neuroplasticity linked with better functional outcomes after stroke. Early evidence suggests that increased concentrations after exercise may be possible for people with stroke, however it is unclear how exercise parameters influence BDNF concentration. Methods: This systematic review and meta-analysis searched 7 electronic databases
Network Meta-Analysis of Non-Conventional Therapies for Improving Upper Limb Motor Impairment Poststroke.
Saikaley, Marcus BSc; Pauli, Griffin MD (c), MSc; Sun, Hao MSc (c); Serra, Julisa Rodriguez BSc; Iruthayarajah, Jerome MSc; Teasell, Robert MD
doi : 10.1161/STROKEAHA.122.040687
Network meta-analysis is a method that can estimate relative efficacy between treatments that may not have been compared directly within the literature. The purpose of this study is to present a network meta-analysis of non-conventional interventions to improve upper extremity motor impairment after stroke.
Workflows and Outcomes in Patients With Suspected Large Vessel Occlusion Stroke Triaged in Urban and Nonurban Areas.
Garcia-Tornel, Alvaro MD, PhD; Millan, Monica MD, PhD; Rubiera, Marta MD, PhD; Bustamante, Alejandro MD, PhD; Requena, Manuel MD, PhD; Dorado, Laura MD, PhD; Olive-Gadea, Marta MD, PhD; Jimenez, Xavier MD, PhD; Soto, Angels RN; Querol, Marisol RN; Hernandez-Perez, Maria MD, PhD; Gomis, Meritxell MD, PhD; Cardona, Pere MD, PhD; Urra, Xabier MD, PhD; Purroy, Francesc MD, PhD; Silva, Yolanda MD, PhD; Ustrell, Xavier MD, PhD; Esteve, Patricia MD, PhD; Salvat-Plana, Merce RN, PhD; Gallofre, Miquel MD, PhD; Molina, Carlos MD, PhD; Davalos, Antoni MD, PhD; Jovin, Tudor MD, PhD; Abilleira, Sonia MD, PhD; Ribo, Marc MD, PhD; Perez de la Ossa, Natalia MD, PhD; for the RACECAT Trial Investigators; Jacobi, Marc Ribo Dr; Sanjuan, Estela; Santana, Katherine Dr; Rodriguez, Noelia Dr; Pagola, Jorge Dr; Rodriguez-Luna, David Dra.; Maisterra, Olga Dr; Santamarina, Estevo Dra.; Muchada, Marian Dr; Juega, Jesus Dra.; Boned, Sandra Dr; Franco, Antonio Palasi Dr; Garcia -Tornel, Alvaro Dra.; Deck, Matias Dr; Sala, Victoria; Munoz, Lucia Dra.; Millan, Monica Dra.; Lopez-Cancio, Elena Dra.; Hernandez-Perez, Maria; Ciurans, Jordi; Samaniego, Daniela; Canento, Tamara; Martin, Lorena; Planas, Anna; Broto, Joaquin; Sorrentino, Agustin; Pare, Marti; Zhu, Nuole; Garrido, Alicia; Grau, Laia; Crespo, Ane Miren; Presas, Silvia; Almendrote, Miriam; Ramos, Alba; Lucente, Giuseppe; Ispierto, Lourdes; Lozano, Manuel; Becerra, Juan Luis; Jimenez, Marta; Rolan, Dolores Vilas; Guanyabens, Nicolas; Sanchez-Ojanguren, Josep; Martinez-Pineiro, Alicia; Forcen, Sara; Gea, Mireia; Alvarez, Marta; Ramos, Anna; Lizarbe, Manuel Dominguez; Guerra, Sara, Rubio; Bragado, Irene; Arbex, Andrea; Rodriguez, Luis; Portela, Pere Cardona Dr.; Garcia, Helena Quesada Dra.; Rodriguez, Blanca Lara Dra.; Cayuela, Nuria Dra.; Miro, Julia Dra.; Marzal, Clara Dr; Paipa, Andres Dr; Campoy, Sergio Dra.; Nunez, Ana Dr; Arroyo, Pablo Dra.; Besora, Sarah Dra.; Adell, Vanessa Dr; Campdelacreu, Jaume Dra.; Marti, Montse Alemany Dra.; Gonzalez, Belen Dra.; Vila, Laura Bau Dra.; Crespo, Marta Fiter; Berbel, Anna; Urbaneja, Ma. Cristina Villaescusa; Guillen, Nuria Dra.; Vidal, Nuria; Verez Santamaria, Patricia Valentina; Navarro, Diego Herrero; Simo, Marta; Falip, Mercedes; Matas, Elisabeth; Ochoa, Neus Mongay; Gifreu, Ariadna; Munoz, Albert; Romero, Lucia; Portell, Eduard; Perez, Guillermo Hernandez; Esteve, F. Ruiz; Teixidor, Silvia; Talavera, Augusto Salazar Dra.; Gomez, Roser; Nuin, Xabier Urra Dr; Vargas, Martha; Chamorro, Angel; Amaro, Sergio; Llull, Laura; Renu, Arturo; Rudilosso, Salvatore; del Valle, Raquel Sanchez; Arino, Helena; Sola, Nuria; la Puma, Delon; Gil, Francisco; Gomez, Juan Bernardo; Matos, Nuria; Falgas, Neus; Borrego, Sergi; Sanchez, Almudena; Balasa, Mircea; Montejo, Carmen; Guasp, Mar; Reyes, David; Cervilla, Pablo Sanchez; Contador, Jose Miguel; Vera Monge, Victor Augusto; Ramos, Oscar; Rodriguez, Alejandro; Campello, Ana Rodriguez Dra.; Ballester, Gemma Romeral; Trujillano, Mireia Llop; Steinhauer, Eva Giralt; Godia, Elisa Cuadrado; Ois Santiago, Angel Javier; Conde, Jordi Jimenez; Fabregas, Joan Marti Dr; Guisado, Daniel Dr; Prats, Luis Dr; Camps, Pol Dra.; Delgado, Raquel Dr; Domeno, Alejandro Martinez; Marin, Rebeca; Canovas, David; Estela, Jordi; Ros, Marta; Aranceta, Sonsoles; Espinosa, Jordi; Rubio, Marta; Lafuente, Cristina; Barrachina, Oriol; Anguita, Alicia; Reverter, Anna; Garcia, Carmen; Sansa, Gemma; Hervas, Mariona; Crosas, Monica; Delgado, Tania; Krupinski, Jerzy Dr; Folch, Sonia Huertas Dra; Gamito, Gemma Munoz; Alvarez, Josep Trenado; Subirana, Teresa; Molina, Jessica; Besora, Sarah; Romero, Laura Comes; Valls, Gemma Guardia; Jover, Miriam; Sotova, Javier Joaquin; Garcia Sanchez, Sonia M[feminine ordinal indicator] Dra.; Valenzuela (intensivista), Sebastian Dr; Gomez-Choco, Manuel Dr; Mengual, Juan Jose; Font, M. Angels; Gomez Ruiz, M[feminine ordinal indicator] Isabel Dra.; Zubizarreta, Irati; Gonzalez, Susana Fernandez; Gubieras, Laura; Cobos, Carmen E.; Romo, Luis Mena; Caballol, Nuria; Cano, Luis; Leal, Joaquin Serena Dr; Izarra, Mikel Terceno; Trigo, Irene Bragado; Viturro, Saima Bashir; Albinana, Laura Pardo; Garrido, Montserrat Reina; Cazcarra, Carla Marco; Uscamaita, Karol Enrique; Marquez, Fabian; Coll, Cristina; Lloret Villlas, Mar Irida; Vila, Berta Solano; Alemany Perna, Berta; Dominguezl, Daniel Lopez; de Lera, Mercedes; Cots Foraster, Anna; Vera Monge, Victor Augusto; Bojaryn, Urszula; Benabdelhak, Ikram; Capdevila, Gerard Mauri; Sanahuja Montesinos, Jordi; Vazquez, Daniel; Vicente Hervas, Jose; Gonzalez, Cristina; Quilez, Alejandro; Pascual, Mikel Vicente; Ruiz, Maria; Riba, Yolanda; Gil Villar, M. Pilar; Garcia, Cristina; Roig, Xavier Ustrell Dr; Mora, Monica Baldrich; Guinjoan, Anna Pellise; Borras, Judit; Mane Martinez, Alba; Mares, Rafael; Vinas i Gaya, Jaume; Sero, Laia; Flores, Alan; Rodriguez, Paula Dra; Castilho, Gislaine; Ortega, Angela Monterde; Reverte, Silvia; Zaragoza, Josep; Baiges, Joan Josep; Zaragoza, Josep; Ozaeta, Gisela Martin Dr; Escalante, Sonia; Payo, Iago; Salvado, Julia Saura Dra.; Sala, Natalia Mas; Soler Insa, Josep M; Vilamala, Ester Tio; Navarro, Josep Abos Dr; Tabuenca, Hector Cruz Dra.; Canento Sanchez, Tamara Dra.; Ros, Marta Dra.; Matos, Nuria; Roldan, Elisabet; Rubiol, Elsa Puiggros Dra.; Franquet, Elisabet; Fuentes, Lidia; Donaire, Javier; Marti, Elena; Gimenez, Laura; Vazquez, Junior Gil; Clara Gris Ambros, Eloisa Nieto; Rodriguez, Puri; Oletta, Jose Felix; Mellado, Pilar Pons Dra.; Gomez, Catena, Barbara; Raileau, Vergilin; Ruiz, Esther Catena Dra.; Pardina, Oscar; Mercadal, Jordi; Lopez-Dieguez, Maria; Perez, Pilar; Gabarro, Lourdes; Orriols, Maria; Canet, Joan Josep; Roca, Mireia; Alvaro, Muriel; Boneu, Francesc; Gimenez, Georgina; Alba, Jaume; Gibert, Francesc; Garcia, Jessica; Barragan, Patricia; Jurado, Gustavo; Ortega, Josep Sabate; Martinez Solano, Joan Amaurys; Fernandez, Victor; Torres, Monica; Belen Montero Alvaredo, Ana; Redondo Parejo, Laura Dra.; Maria Aragones, Josep Dra.; Bullon, Anna Dra.; Loste, Cora Dra.; Gonzalez, Paula Dr; Bejarano, Neker Dr; Sanchez, Francisco Dr; Lucchetti, Gianni Dr; Pla, Xavier Dr; Gimeno, Javier Dr; Reynaga, Esteban Dra.; Barcons, Montse Dr; Celedon, Gabriel Dr; Ortiz, Juan Dr; Anastasovski, Goran Dr; Mascaro, Oscar Dr; de los Rios, Javier Diez Dra.; Feliu, Meritxell Dra.; Ribera, Anna Dr; Ruiz, Cristhian Dr; Corominas, Gerard; Nunes, Daniella Dra.; Roca, Claudia Dra.; Latorre, Nadina Dra.; Yataco, Lizbeth Dra.; Cruz, Maricelys Dra.; Blanco, Nerea Dr; Castejon, Santiago; Calderon, Dolores Cocho Dra.; Sunyer, Claustre Pont; Garcia, Jordi Espinosa; Martin, Rodrigo Paz; de Luis Sanchez, Albert; Vivas, Dolores Espinosa; Molina, Gemma, Juan Valencia; Palome, Planels; Chaume, Laia Tomas; Vilella, Ares Villagrasa; Bustamante, Marco; Boltes, Anunciacion; Rodriguez, Fernando; Arrieta, Itziar; Ciurans Molist, Jordi Dra.; Andreu, Barnes; Soler, Ernest Palomeras Dr; Busca, Nicolau Guanyabens; Lopez, Manuel Daza; Farreres, Jordi Bigas; Ruiz, Virginia Casado; Batiste, Desiree Muriana; Sanz Cartagena, M[feminine ordinal indicator] Pilar; de Vega, Eulalia Cabot; Real, Josep Bassa; Roman, Hector Pelaez; Socolich, Cesar; Alonso Camp, Josep M[feminine ordinal indicator]; Cano Orgaz, Antonio Tomas; Fossas Felip, M[feminine ordinal indicator] Pilar; Moron, Nicolas; Bacca, Sandra; Molina, Mauricio; Casarramona, Francesc; Elias, Lorena; Bukaei, Muhammad Zidane; Martos Gutierrez, Jose Antonio; Escuin, Judith Lopez Dra.; Olaizola, Cristina; Vargas, Yolexis Lopez; Jimenez Oyonarte, Juan; Soultana, Rashida; Golpe, Eduardo Sanjurjo Dr.; Salvador, Esther Dr; Vila, Guillem Dr; Serrano, Marcos; Lopez Claverol, Matilde Nuria Dra.; Lamolla, Marian; Amate, Miquel; Rodriguez, Adriana; Romero, Ruth; del Carpio, Montgomery; Hernandez, Ana Isabel; Martin, Julian; Rosas, M Carmen; Nogueroles, Antonio; Encarnacion, Sorilandy; Robles, Augusto; Herrera, Jose Antonio; Gavilan, Roger; Mameghani, Toghrol; Araujo, Gaston; Garrido Morales, M.Angeles; Albert Segui, Enric Ramon; Climent, Eva Fernandez; Pujol, Francesc Paris; Garrofe Seira, Mireia Judit; Pia, Lucia Gomez; Nunez, Fernando Salleres; Penalver, Cristina Aguar; Lopes, Cristina Vaz; Ribera Tasa, Elisenda; Vilchez, Carmen Repullo; Zambrana, Modesto Sanchez; Ribas, Beatriu Suescun; Panes, Ines Vila; Planavila, Montserrat Vila; Lorenzo, Alicia Vaqueiro; Guixes, Meritxell Sabartes; Medina, Jorge; Sambrano, David; Zamarreno, Javi; Pirela, Carmen; Velez, Paola; Cajamarca, Luis; Perez, Honey; Martinez, Yarles; Alexander Goncalves, Jesus; Regordosa, Carles; Mormeneo, Claudia; Griu, Laura; Francia Colina, Maria; Farik, Enric; Duch, Dolors Carrion Dra.; Badenas, Carles; Bernal, Oscar; Agramunt, Nuria; Morales, Shyrlei; Reynoso, Victoria; Guerrero, Miguel; Romera Cid, Primitivo; Folque, Monica; Pedroza, Claudia; Hachem, Adnan; Martinez, Inigo Soteras Dr; Verdera Garcia, Xavier; Amoros, Merce Lopez Dra.; Subiros, Xavier Costa Dra.; Benet, Marta Cufi; Van Eendenburg, Cecile; Osuna, Teresa; Santos, Dra Gina; Pallisera, Mireia Dra.; Oliva, Lluis Gonzalo; Sanchez, Gemma Dra.; Basurto, Xavier Dr; Vivoda, Ludgi Dr; Van der Kleyn, Richard; Robles, Laura Dra.; Cabanelas Barranco, Ana Dra.; Almendros, M[feminine ordinal indicator] Cruz; Oliveras, Marc Perez; Alvarez, Amelia Fernandez; Rybyeva, Maria; Vinas, Antoni; Barcons, Maria; Alberto Tavera, Joaquim Danes; Burbano, Pablo; Lopez, Cintie; Cruz, David; Bisbe, Paula; Fernandez, Nora; Carlos Palacio, Juan; Fraiz, Eduardo; Aguilo, Oriol; Amorodjo, Rollmy; Velazquez, John; Sanchez, Elena; Espanol, Jaume; de Celis, Judit Perez; Coll, Anna; Diaz, Gloria; Verges i Sala, Margarida; Casas Capdevila, M[feminine ordinal indicator] Angels; Ferrini, Yosmairy Yoselin; Gorriz, Aitor; Cucurell Navarro, Diego-Javier; Velasquez, Dulce; Pla Soler, Jaume; Gonzalez, Josep; Higuera, Julian David; Cuellar, Lina; Miniello, Liza Margarita; Pujol, Lluis; Cracan, Sorin; Vives, Mora; Angela, M; Lopez, Lopez; Anabel,; Molist, Montse Gorchs; Anna, Delofeu; Munoz, Silvia Sola; Yolanda, Ferreres; Pujalte, Carol; Tellez Marin, Elisabeth; Font Casas, Yolanda; Hernandez Luque, Sara; Sendra, Joaquim Mejias; Valero, Francesca Mellado; Escala, Campos; Lacanal, Galup De; Diaz, Lopez; Paramio, Castillo; Estopa, Catala; Moreda, Espanol; Majo, Calafell; Almeida, Carballo; Naval, Castro; Elena, M; Ruiz, Cregut; Lluis, Pere; Font, Deulofeu; Sanjuan, Fabregat; Pere, Joan; Gorchs, Fontquerni; Belles, Fores; Antoni, Joan; Herrera, Gomez; Carlos, Juan; Prades, Hijazo; Torvisco, Itzaina; Rovira, Marti; Gonzalez, Obiols; Cavero, Olive; Gil, Querol; Soledad, M; Rodriguez, Rico; Sambernardo, Rios; Molina, Ropero; Ramon, Jose; Valero, Sanchez; Arevalo, Santos; Jose, Maria; Garcia, Soto; Angeles, Maria; Escribano, Tebar; Garcia, Torres; Jose, Pedro; Carrion, Verdes; Isabel, M; Lopez, Verge; Jose, Juan; Canela, Lopez; Angeles, M; Guarque, Lucas; Alvarez, Morales; Arnulfo, Jorge; Fornieles, Morell; Gomez, Subirats; Teresa, Maria; Masa, Torello; Lopez, Val; Mercedes, Maria; Reyes, Palmero; Manuel, Juan; Forne, Rodriguez; Turiel, Ruana; Gonzalez, Sanchez; Gornals, Sebastia; Rico, Abrio; Falip, Albert Gual; Oliveros, Aznar; Perotti, Brugues; Molinero, Calvet; Franco, Catells; Medina, Corrales; Miro, Daroca; Marquez, Duran; Pradas, Feliu; Casanova, Figueras; Tortajada, Garcia; Gallego, Grajera; del Mar, Azahara; Arroyo, Las; de Jesus, Dulcenombre; Sanz, Laserreta; Vidal, Llambrich; Corral, Monllao; de la Cruz, Morales; Blanco, Moreno; Orgaz, Orejuela; Suazo, Pinana; Minguillon, Pons; Gomez, Rodriguez; Carlos, Jose; Pereira, Rodriguez; Porcel, Sedo; Villar, Sevil; Lopez, Sierra; Romero, Torres; Calveres, Trepat; Arnella, Ventura; Gil, Acera; Teresa, M; Vico, Biesot; Galea, Castro; Maria, Rosa; Chafer, Escorcia; Antonio, Juan; Moreda, Espanol; Faure, Gil; Luque, Hernandez; Delgado, Jimenez; Gay, Mallafre; Angel, M.; Sanzo, Olivares; Fondevila, Pubill; Fort, Sabate; Agamez, Segovia; Carlos, Antonio; Longaretti, Turata; Hernandez, Valle; Guixens, Trayner; Valor, Aguilar; Alvarez, Aguirre; Naval, Alastrue; Baquero, Alferez; Marne, Cristina, Alonso; Orozco, Aloy; Colino, Alvarez; Penuela, Alvarez; Cirilo, Ameller; Vanessa, Maria; Guerrero, Andujar; Remedios, Estefania; Sillero, Auladell; Sorbet, Azcarate; Genesca, Basany; Barduena, Benavent; Tudela, Benito; Pardo, Blanch; Pla, Boluda; Gonzalez, Bonilla; Serramalera, Bru; Andreu, Burnat; Calvo-Rayo, Caballero; Casellas, Calvo; Mombiela, Camps; Bresme, Cano; Fernandez, Carcelen; Sola, Caro; Matavacas, Casasas; Bolado, Castanedo; Cortina, Cerdena; Jane, Abella; Collado Borrego, Laia; Orri, Colom; Vilanova, Comellas; Sole, Conillera; Torres, Cots; Estepa, Cuchi; Graell, de Sostoa; Lopez, del Rio; Compte, Delgado; Bueno, Diaz; Maneiro, Diaz; Lucia, Andrea; Palau, Domenech; Carme, M.; Carasso, Duran; Javier, Pablo; Marquez, Duran; Abidi, El; Martin, Escoda; Casanovas, Esteve; Perez, Fernandez; Quintero, Ferre; Escobar, Flores; Abad, Fontcuberta; del Valle, Fortes; Luisa, M[feminine ordinal indicator]; Quesada, Franco; Maria, Sara; Romero, Franco; Teresa, Maria; Francisco, Gallego; Gala, Alicia, Gamiz; Castaneda, Garcia; Rodriguez, Garcia; Gemma, Casajuana; Arroyo, Gomez; Girbau, Gomez; Fernandez, Gonzalez; Gonzalez, Gonzalez; Gonzalez, Gonzalez; Lopez, Gonzalez; Obeso, Gual; Blanco, Guerrero; Roca, Guillemas; Eudaldo, Guillermo; Sebastia, Hernandez; Covas, Homar; Alvarez, Hostench; Royo, Huerta; Barcelo, Ibanez; Cruz, Izquiero; Urdangarin Etxetxikia, Jaione; Gimenez, Juarez; Alami, Khlifi; Gasco, Laparra; Moreales, Lara; Arroyo, Las; de Jesus, Dulcenombre; Medina, Lasaosa; Lourdes, Maria; Cava, Lazaro; Berrar, Leon; Maturana, Lopez; Ramirez, Lopez; Romero, Lopez; Marco, Lorente; Martin, Lorenzo; Casals, Lozano; Nicola, Lujan; Diaz, Madrid; Antonio, Jose; Peris Morales, Maria Teresa; Clemente, Marti; Castano, Martinez; Natanael, David; Gamez, Martinez; Gonzalez, Martinez; Quesada, Martinez; de la Cabeza, Maria; Fuste, Mireia, Marza; Conillera, M; Lasheras, Melendo; Mestre, Miralles; Puig Pastalle, Montserrat; Vidal, Montserrate; Mellado, Mora; Ponce, Morales; Fornieles, Morell; Cabre, Morera; Vivet, Morera; Souza, Mundi; Quiles, Munoz; Rosa, Navea; Iglesias, Neira; Asuncion, M; Manrique, Nunez; Pilar, M[feminine ordinal indicator]; Martinez, Obiols; Reig, Pallares; Torres, Partegas; Berengueras, Pascual; Gamez, Perez; Oset, Perez; Restrepo, Perez; Alejandra, Maria; Yeste, Planas; Mangado, Planells; Minguillon, Pons; Carbonell, Puertas; Blanco, Quinteiro; Benavente, Rebollar; Fernandez, Recasens; Gomez, Reyes; del Carmen, Maria; Pou, Roca; Ferrer, Rodriguez; Franco, Rodriguez; Fuertes, Rodriguez; Munoz, Rodriguez; Navarro, Rodriguez; Iniesta, Roig; Gracia, Romero; Brunet, Rovira; de Eugenio, Rovira; Baena, Rubio; Llorens, Ruiz; Llamazares, Sala; Alaez, San Juan; Segura, Sanchez; Soldevilla, Santasusana; Salmeron, Sanz; Perez, Segura; Balcells, Serra; Dumitras, Sorina; Montoya, Teixidor; Vicente, Tena; Salinas, Tierno; Ines, Ester; Testa, Toledo; Figueras, Tomas; Ruperez, Tomas; Garcia-Penche, Torrano; Esparza, Torres; Uku, Florenc; Blanco, Vazquez; De la Paz, Vazquez; Gil, Vazquez; Gonzalez, Vazquez; Meler, Vidal; Cots, Vilalta; Jimenez, Vilches; Jose, Maria; Fernandez, Visser; Gavin, Viu; Vives, Vives; Jimenez, Carmona; Jose, Francisco; Vilches, Galobardes; Gomez, Gonzalez; Manzanera, Jodar; Cortes, Marimon; Orive, Marrodan; Bosch, Martin; Jose, Maria; Lopez, Martorell; Roca, Millares; Jesus, M; Guri, Miralles; Hernandez, Muliterno; Oliva, Munoz; Pujol, Pons; Conde, Postius; Arrunada, Prieto; Antonio, Jose; Mathe, Quintana; Mata, Rosell; Alvarez, Aguirre; Alvarez, Alvarin; Flores, Arrufat; Pago, Banuelos; Andreu, Burnat; Vilar, Campo; Hidalgo, Cardus; Gil, Castello; Gloria, Maria; Montsesinos, Castrillo; Estopa, Catala; Garces, Clave; Sanroma, Comes; Sequi, Descalzo; Ricol, Errando; Campillo, Escudero; del Mar, Maria; Alvarez, Fernandez; Gomez, Fernandez; Perez, Fernandez; Espinosa, Franch; Graells, Freixes; Plaza, Garcia; Gallego, Garcia-Marron; Simancas, Hernandez; Covas, Homar; Royo, Huerta; Armas, Jaraba; Ramos, Jimenez; Canela, Lopez; Angeles, M; Lopez, Lopez; Oganissian, Lopez; Romero, Madrona; Rosa, M; Millan, Martinez; Moron, Martinez; Encinas, Merchan; Fornieles, Morell; Jimenez, Moreno; Rico, Munoz; Rodriguez, Navarro; Ibanez, Nogales; Maria, Rita; Viera, Novillo; Torrabadella, Parella; Alba, Mari; Villar, Pera; Montserrat, Carla; Carbonell, Puertas; Miralles, Rabella; Trilles, Ramis; Ortiz, Ribera; Fuertes, Rodriguez; Gonzalez, Sanchez; Perez, Sastre; Perez, Segura; Borrega, Soro; Garcia, Soto; Angeles, Maria; Fores, Tapia; Bernad, Tellez; Alvarez, Trenado; Moreda, Espanol; Martin, Felix; Perez, Herrero; Manzanera, Jodar; Fuster, Lanau; Gomariz, Lopez; Orive, Marrodan; Bosch, Martin; Jose, Maria; Guri, Miralles; Oliva, Munoz; Lozano, Pardo; Pujol, Pons; Altimiras, Quintana; Lopez, Ventosa; Damian, Almodovar; Colino, Alvarez; Monterroso, Alvarez; Comas, Arambudo; Garzon, Boullon; Capella, Burgos; Garcia, Campuzano; Del Mar, Maria; Olivas, Capdevila; Fernandez, Carcelen; Sola, Caro; Marti, Carre; Isabel, Clara; Bacaicoa, Carretero; Gil, Castello; Gloria, Maria; Montsesinos, Castrillo; Calderon, Cazorla; Osuna, Chacon; Planas, Cortes; Olio, Cortit; Estany, Delhomme; Carasso, Duran; Javier, Pablo; Campillo, Escudero; del Mar, Maria; Martinez, Fructuos; Lopez, Garcia; Luis, Pascual; Plaza, Garcia; Amill Vallve, Genis; Arroyo, Gomez; Girbau, Gomez; Munoz, Gonzalez; Ventura, Hernaez; Covas, Homar; Gimenez, Lavernia; Rojo, Martin; Medina, Martinez; Millan, Martinez; Barrera, Mayol; Pi, Mercader; Dalmau, Merino; Campodarbe, Miguel; Pastalle, Montserrat Puig; de la Cruz, Morales; Fornieles, Morell; Sanchez, Moreno; Javier, Francisco; Reig, Pallares; Torrabadella, Parella; Mari, Alba; Barrameda, Penela; Ajenjo, Prieto; Benavente, Rebollar; Pareja, Rodriguez; Pinar, Rodriguez; Francisco, Javier; Tello, Rodriguez; Pereda, Romero; Saborido, Sainz; Martin, Santacana; Martinez, Santos; Chavez, Sierra; Testa, Toledo; Figueras, Tomas; Garcia, Torres; Jose, Pedro; Torres, Turbau; Domenech, Vicente; Esteo, Villena; Pertegaz, Vives; Gonzalez, Baena; Pont, Bagaria; Sanchez, Beltran; Alarcon, Bonet; Ballesca, Borch; Clanchet, Buhils; Garcia, Closa; Carril, Colomina; Sanchez, Cristina Fernandez; Edurne Judith, Fernandez Toledo; Rodriguez, Espases; Resa, Espert; Xavier, F; Sol, Fernandez; Lugo, Gonzalez; Llesera, Gracia; Lendinez, Herrada; Liesa, Juliench; Alicia, Sandra; Ortega, Lopez; Yuste, Lopez; Villanueva, Lozano; Soto, Lucia Sola; Castellano, Madrid; Cano, Megias; Jesus, Daniel; Ponce, Montasell; Sospedra, Montesinos; Martinez, Moya; Herrera, Munoz; Isabel, M; Fernandez, Ocana; Jose, Maria; Bernal, Palau; Sole, Perez; Carbonell, Ramon; Lop, Ribas; Lopez, Rubio; Lopez, Rueda; Castano, Sabat; Lara, Sabata; Ramirez, Salmeron; Gornals, Sebastia; Creus, Serra; Dalmau, Serrano; Mainero, Sumasi; Gabriel, Gonzalo; Masa, Torello; Primo, Valencia; Vinuales Munoz, Ana Maria; Roig, Josep; Hidalgo., Veronica
Fingolimod Does Not Reduce Infarction After Focal Cerebral Ischemia in Mice During Active or Inactive Circadian Phases.
Mandeville, Emiri T. MD, PhD; Li, Wenlu PhD; Quinto-Alemany, David PhD; Zhang, Fang MD, PhD; Esposito, Elga PhD; Nakano, Takafumi PhD; Mandeville, Joseph B. PhD; Lee, Janice PhD; Park, Ji Hyun PhD; Arai, Ken PhD; Waeber, Christian PhD; Lizasoain, Ignacio MD, PhD; Moro, Maria Angeles PhD; Lo, Eng H. PhD
doi : 10.1161/STROKEAHA.122.039932
It has been reported that the S1P (sphingosine 1-phosphate) receptor modulator fingolimod reduces infarction in rodent models of stroke. Recent studies have suggested that circadian rhythms affect stroke and neuroprotection.
Notch Signaling Mediates Radiation-Induced Smooth Muscle Cell Hypermuscularization and Cerebral Vasculopathy.
Yang, Yuhua MD ,*; Li, Honghong MD, PhD ,*; Xu, Yongteng MD ,*; Xie, Jiatian MD; Liu, Qiang MD, PhD; Shi, Zhongshan PhD; Huang, Jialin MD; Cheng, Jinping MD, PhD; Chen, Siqi MD; Chen, Sitai MD; Zhao, Xiaohui MD; Li, Shaojian MD; Zhang, Zhan MS; Cai, Jinhua MD, PhD; He, Baixuan MD, PhD; Lin, Wei-Jye PhD; Shen, Qingyu MD, PhD; Li, Yi MD, PhD; Tang, Yamei MD, PhD
doi : 10.1161/STROKEAHA.122.040697
Emerging evidence highlighted vascular injury in aggravating radiation-induced brain injury (RIBI), a common complication of radiotherapy. This study aimed to delineate the pathological feature of cerebral small vessel and investigate the functional roles of Notch signaling in RIBI.
Contemporary Incidence and Burden of Cerebral Venous Sinus Thrombosis in Children of the United States.
Otite, Fadar Oliver MD, SM; Vanguru, Husitha MD; Anikpezie, Nnabuchi MD, DrPH; Patel, Smit D. MD, MPH; Chaturvedi, Seemant MD
doi : 10.1161/STROKEAHA.122.039822
The incidence of cerebral venous thrombosis (CVT) in children of the United States is unknown, and it is uncertain how the burden of CVT hospitalizations in children changed over the last decade
Misery Perfusion and Tau Deposition in Atherosclerotic Major Cerebral Artery Disease: A 18F-Florzolotau Positron Emission Tomography Study.
Yamauchi, Hiroshi MD, PhD; Kagawa, Shinya PhD; Kusano, Kuninori RT; Ito, Miki RT; Okuyama, Chio MD, PhD
doi : 10.1161/STROKEAHA.122.040493
Studies using animal models have shown that cerebral hypoperfusion causes hyperphosphorylation of tau protein, leading to neuronal damage. However, the relationship between hypoperfusion and tau deposition in humans is unclear.
Elevated Cortical Tau Positron Emission Tomography Binding in Misery Perfusion: Novel, Puzzling, and Heuristic.
Baron, Jean-Claude MD, ScD
Diurnal Differences in Immune Response in Brain, Blood and Spleen After Focal Cerebral Ischemia in Mice.
Esposito, Elga PhD ,,*; Zhang, Fang MD, PhD ,,*; Park, Ji-Hyun PhD; Mandeville, Emiri T. MD PhD; Li, Wenlu PhD; Cuartero, Maria Isabel PhD; Lizasoain, Ignacio PhD; Moro, Maria A. PhD; Lo, Eng H. PhD
doi : 10.1161/STROKEAHA.122.040547
The immune response to acute cerebral ischemia is a major factor in stroke pathobiology. Circadian biology modulates some aspects of immune response. The goal of this study is to compare key parameters of immune response during the active/awake phase versus inactive/sleep phase in a mouse model of transient focal cerebral ischemia.
Interaction of Mean Arterial Pressure and Blood Pressure Variability in Critically Ill Brain Injured Patients.
de Havenon, Adam MD, MS; Petersen, Nils H. MD, PhD; Stulberg, Eric L. MD, MPH; Anadani, Mohammad MD; Biffi, Alessandro MD; Sheth, Kevin N. MD
Progressive Cervical Myelopathy With Medullary Involvement as a Presentation of Dural Arteriovenous Fistula.
Barros, Francisco Millet MD; Machado, Rita MD; Carneiro, Diogo MD; Gens, Helena MD; Santo, Gustavo Cordeiro MD
Navigating an Internal Carotid Artery Anatomic Variant During Endovascular Therapy for Acute Ischemic Stroke.
Peng, Teng J. MD; Sharma, Richa MD; Antonios, Joseph P. MD, PhD; Hebert, Ryan MD; Jasne, Adam S. MD
Four-Dimensional Flow Magnetic Resonance Imaging Analysis of Cerebral Aneurysm in the Carotid Rete Mirabile.
Kawano, Hiroto MD; Yamada, Shigeki MD, PhD; Tsuji, Atsushi MD, PhD; Tsuji, Keiichi MD, PhD; Nozaki, Kazuhiko MD, PhD
Pulmonary Arteriovenous Fistula Leading to Artery of Percheron Infarcts.
Paramasivan, Naveen Kumar MD, DM; Valakkada, Jineesh MD; Sreedharan, Sapna Erat MD, DM; Sylaja, P.N. MD, DM
Advances in Neurocardiology: Focus on Anticoagulation for Valvular Heart Disease With and Without Atrial Fibrillation.
Gurol, M. Edip MD, MSc; Sposato, Luciano A. MD, MBA
Updates on Sturge-Weber Syndrome.
Yeom, SangEun BS; Comi, Anne M. MD
doi : 10.1161/STROKEAHA.122.038585
AB Sturge-Weber syndrome (SWS) is a rare, noninherited neurovascular disorder characterized by abnormal vasculature in the brain, skin, and eye. Patients with SWS characteristically have facial capillary malformation, also known as port-wine birthmark, a leptomeningeal vascular malformation seen on contrast-enhanced magnetic resonance imaging images, abnormal blood vessels in the eye, and glaucoma.
Recent Advances in Neuropsychological Outcomes and Intervention in Pediatric Stroke.
Krivitzky, Lauren S. PhD ,*; Westmacott, Robyn PhD ,*; Boada, Richard PhD ,*; Sepeta, Leigh PhD ,*; Reppert, Lauren BA; Mrakotsky, Christine PhD ,*
doi : 10.1161/STROKEAHA.122.037294
AB Over the past 15 years, there have been significant advances in the treatment of acute and chronic medical consequences of stroke in childhood. Given high rates of survival in pediatric stroke, practitioners are tasked with treating the ongoing motor and neuropsychological sequelae in patients over the course of their development
Percutaneous Transluminal Angioplasty and Stenting for Vertebral Artery Stenosis.
Xu, Ran MD, PhD ,,*; Zhang, Xiao MD ,,*; Liu, Sihua MD; Wang, Xue BS; Wang, Wenjiao BS; Yang, Kun MD, PhD; Wang, Tao MD; Dmytriw, Adam A. MD; Bai, Xuesong MD; Ma, Yan MD; Yang, Bin MD; Jiao, Liqun MD, PhD
December Literature Synopses.
Hurst, David A. BS; Sohrabji, Farida PhD
International Section for Early Career and Training.
Georgakis, Marios K. MD, PhD; Malik, Rainer PhD
Correction to: Controversies in Stroke: Should Patients With Embolic Stroke of Undetermined Source Undergo Intensive Heart Rhythm Monitoring With an Implantable Loop Recorder?.
Correction to: A Family and a Genome-Wide Polygenic Risk Score Are Independently Associated With Stroke in a Population-Based Study.
Correction to: Effectiveness and Safety of Anticoagulation Therapy in Frail Patients With Atrial Fibrillation.
