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Liver Tumours in Children: The Hepatologist's View
Kelgeri, Chayarani?; Renz, Diane†; McGuirk, Simon‡; Schmid, Irene§; Sharif, Khalid||; Baumann, Ulrich¶
doi : 10.1097/MPG.0000000000003006
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p 487-493
Diagnostic and therapeutic innovations have changed the way we now approach liver tumours in children and adolescents. Novel imaging tools, increasing awareness, and surveillance has led to early diagnosis of benign and malignant liver tumours. Multidisciplinary interventions have favourably altered the natural course in some liver tumours. The role of liver transplantation is expanding and has become fully integrated into today's therapeutic algorithms. Transarterial locoregional and ablation therapies have been successful in adults and are being explored in children to facilitate resectability and improve outcome. For the first time, North American, Japanese, and European experts have designed a global trial to optimize management of malignant liver tumours and aim to find signature molecular profiles that will translate to individualised treatment strategies.
Rectal Biopsy Technique for the Diagnosis of Hirschsprung Disease in Children: A Systematic Review and Meta-Analysis
Comes, Giovana Tuccille?; Ortolan, Erika Veruska Paiva?; de Medeiros Moreira, Maressa Maria†; de Oliveira Junior, Wilson Elias?; Angelini, Marcos Curcio?; El Dib, Regina‡; de Arruda Lourenç?o, Pedro Luiz Toledo?
doi : 10.1097/MPG.0000000000003041
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p 494-500
The diagnosis of Hirschsprung disease (HD) depends on the histopathological analysis of rectal biopsies. This review aims to define the best rectal biopsy technique. A systematic literature review and proportional meta-analysis of the available case series studies of rectal biopsies were performed in this study. All case series with more than five rectal biopsies in children younger than 18 years of age suspected of HD that described at least one type of rectal biopsy were included. The studies that did not specify the rate of conclusive results and the rate of complications of the biopsy procedures were excluded. According to the literature review, there were four different techniques of rectal biopsy: open, suction, punch, and endoscopic. In the title and abstract screening process, we assessed 496 articles, 159 fulfilled the eligibility criteria, and 71 studies reported our outcomes of interest and were included in the meta-analysis. The pooled proportion of conclusive results was 94% in open biopsies (95% CI 0.89–0.98), 95% in punch (95% CI 0.90–0.98), and 88% in suction group (95% CI 0.85–0.92). The pooled proportion of complication rates was 2% in open biopsies (95% CI 0.00031–0.04), 0.039% in suction (95% CI 0.00023–0.0006), and 2% in punch biopsies (95% CI 0.00075–0.04). Suction, punch, and open techniques presented comparable rates of conclusive results. In the suction group, the association between different methods of histopathological analysis increased conclusive results rates; however, the punch biopsy was associated with significantly higher complication rates than the suction technique.
Establishing a National Rate of Rectal Biopsy Positivity in the Diagnosis of Hirschsprung Disease
Maassel, Nathan L.; Ozgediz, Doruk E.; Solomon, Daniel G.
doi : 10.1097/MPG.0000000000002960
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p 501-505
Although rectal biopsy has long been established as the criterion standard for the diagnosis of Hirschsprung disease, little to no information exists regarding nationwide rates of rectal biopsy positivity or interinstitutional variability. We sought to determine the national rate of rectal biopsy positivity and factors contributing to institutional variability.
Ferric Carboxymaltose Across All Ages in Paediatric Gastroenterology Shows Efficacy Without Increased Safety Concerns
Sasankan, Natasha?; Duncan, Hazel?; Curtis, Lee?; McGuckin, Christina?; Shannon, Claire?; Barclay, Andrew?; Fraser, Simon?; Nair, Mridula†; Russell, Richard K.?; Hansen, Richard?
doi : 10.1097/MPG.0000000000003003
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p 506-510
The aim of the study was to assess the efficacy, safety and side-effect profile of ferric carboxymaltose (FCM) for correcting IDA in children and adolescents in paediatric gastroenterology, hepatology, and nutrition.
The Effect of Helicobacter pylori on the Presentation and Clinical Course of Coronavirus Disease 2019 Infection
Balamtekin, Necati?; Artuk, Cumhur†; Arslan, Melike?; Gül?en, Mustafa‡
doi : 10.1097/MPG.0000000000003005
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p 511-513
Novel coronavirus 2019 (corona virus disease 2019 [COVID-19]) binds angiotensin-converting enzyme-2 (ACE-2) receptors to enter the cell. These receptors are widely expressed in the intestine, and COVID-19 may cause gastrointestinal symptoms via these receptors during the course of the disease. Helicobacter pylori is known to increase the expression of ACE-2 receptors in the gastrointestinal tract. The aim of this study was to investigate the effects of H pylori on the presentation and clinical course of COVID-19 infections.
The Impact of COVID-19 on Job Prospects and Educational Training for Pediatric Gastroenterology Fellows
Irastorza, Laura E.?; Hopson, Puanani?,†; Ta, Allison‡; Kemme, Sarah§; Mallon, Daniel‡; Lee, Christine K.||
doi : 10.1097/MPG.0000000000003037
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p 514-519
The COVID-19 pandemic has significantly affected graduate medical education with redistribution of trainees, altered clinical care, and decreased research. For graduating trainees, there remains concern that financial stability of health systems will affect the availability of new positions and hiring practices. This survey aims to evaluate the pandemic's impact from pediatric gastroenterology fellows’ perspectives.
Influence of Acid Blockade on the Aerodigestive Tract Microbiome in Children With Cystic Fibrosis
Khalaf, Racha T.?,†; Furuta, Glenn T.?,†; Wagner, Brandie D.§; Robertson, Charles E.||; Andrews, Rachel?; Stevens, Mark J.¶; Fillon, Sophie A.?,‡,#; Zemanick, Edith T.¶; Harris, J. Kirk¶
doi : 10.1097/MPG.0000000000003010
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p 520-527
Acid blockade is commonly prescribed in patients with cystic fibrosis (CF). Growing concerns, however, exist about its possible role in the pathophysiology of pulmonary infections. We aimed to investigate if acid blockade alters esophageal and respiratory microbiota leading to dysbiosis and inflammation.
Point Prevalence of Gastrostomy in a Paediatric Population
Pardy, Caroline?; Kharma, Nasir†; Lau, Rachel†; Kelly, Veronica‡,§; Yardley, Iain?,†
doi : 10.1097/MPG.0000000000003016
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p 528-531
The aim of the study was to determine the prevalence of gastrostomy in a paediatric population.
Initial Experience With Endoscopic Ultrasound-guided Coil Placement for Pediatric Gastric Variceal Hemostasis
Barakat, Monique T.?,†; Foley, Megan A.‡; Gugig, Roberto†
doi : 10.1097/MPG.0000000000003028
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p 532-537
Gastric variceal (GV) bleeding is among the most morbid sequelae of portal hypertension, with mortality ranging from 30% to 50%. Pediatric data focused on endoscopic approaches to management are needed. The present study represents the first pediatric case series of endoscopic ultrasound (EUS)-guided coil placement within feeding vessels as monotherapy for management of GV bleeding.
Megacystis Microcolon Intestinal Hypoperistalsis Syndrome: A Case Series With Long-term Follow-up and Prolonged Survival
Prathapan, Krishnapriya Marangattu?; King, Dale E.?; Raghu, Vikram Kalathur?; Ackerman, Kimberly?; Presel, Tracey?; Yaworski, Jane Anne?; Ganoza, Armando†; Bond, Geoffrey†; Sevilla, Wednesday Marie A.?; Rudolph, Jeffrey A.?; Alissa, Feras?
doi : 10.1097/MPG.0000000000003008
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p e81-e85
Describe clinical characteristics, management, and outcome in a cohort of megacystis microcolon intestinal hypoperistalsis syndrome (MMIHS) patients.
Is Celiac Disease Testing Necessary in Functional Abdominal Disorders? A Study in Predominantly Latino Children
Falcon, Ana C.; Fifi, Amanda C.; Valdes, Lilibet Fernandez; Jaquez, Jessica; Mariaud, Carolina; Saps, Miguel
doi : 10.1097/MPG.0000000000002993
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p 542-545
Functional abdominal pain disorders (FAPDs) are among the most common causes of consultation in general pediatrics and pediatric gastroenterology. The Rome IV criteria recommend testing for celiac disease (CD) in children with irritable bowel syndrome-diarrhea (IBS-D) and leaves testing in cases of other FAPDs to the practitioner's discretion. These recommendations were based on a single study that showed a 4-fold increase of CD among patients with IBS in Italy. It is unclear if these findings can be extrapolated to other populations. Understanding whether those results are reproducible in areas with different racial/ethnic backgrounds can optimize patient care.
Clinical Presentation in Children With Coeliac Disease in Central Europe
Riznik, Petra?; De Leo, Luigina†; Dolinsek, Jasmina‡; Gyimesi, Judit§; Klemenak, Martina?; Koletzko, Berthold||,¶; Koletzko, Sibylle¶,#; Korponay-Szab?, Ilma Rita§,??; Krencnik, Tomaz?; Not, Tarcisio†; Palcevski, Goran††; Sblattero, Daniele‡‡; Werkstetter, Katharina Julia¶; Dolinsek, Jernej?,§§
doi : 10.1097/MPG.0000000000003015
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p 546-551
During the past decades, there has been a shift in the clinical presentation of coeliac disease (CD) to nonclassical, oligosymptomatic, and asymptomatic forms. We assessed clinical presentation of CD in children and adolescents in Central Europe.
The Knowledge About Celiac Disease Among Healthcare Professionals and Patients in Central Europe
Riznik, Petra?; De Leo, Luigina†; Dolinsek, Jasmina‡; Gyimesi, Judit§; Klemenak, Martina?; Koletzko, Berthold||,¶; Koletzko, Sibylle¶,#; Koltai, Tunde??; Korponay-Szab?, Ilma Rita§,††; Krencnik, Tomaz?; Milinovic, Marina‡‡; Not, Tarcisio†; Palcevski, Goran§§; Sblattero, Daniele||||; Werkstetter, Katharina Julia¶; Dolinsek, Jernej?,¶¶
doi : 10.1097/MPG.0000000000003019
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p 552-557
Celiac disease (CD) remains undiagnosed for a long time in many adult and pediatric patients. We assessed the knowledge about CD among healthcare professionals (HCPs) and CD patients in Central Europe (CE).
Pediatric Patients’ and Parents’ Perspectives of Unsedated Transnasal Endoscopy in Eosinophilic Esophagitis: A Qualitative Descriptive Study
Scherer, Corey?; Sosensky, Peri†; Schulman-Green, Dena‡; Levy, Meredith§; Smith, Clinton§; Friedlander, Joel§; Koral, Alex†
doi : 10.1097/MPG.0000000000003029
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p 558-562
Eosinophilic esophagitis is an increasingly common inflammatory disease of the esophagus. Diagnosis and management are based on the histological presence of eosinophils in the esophageal mucosa, often requiring multiple endoscopies with sedation. Unsedated transnasal endoscopy (TNE), an alternative method of assessing the mucosa without the risks of sedation, is now being performed in the pediatric population. This is the first qualitative study on pediatric patients’ and parents’ experiences with TNE.
Predicting Suboptimal Transitions in Adolescents With Inflammatory Bowel Disease
Pearlstein, Haley?; Bricker, Josh†; Michel, Hilary K.?; Afzali, Anita‡; Donegan, Amy M.?; Maltz, Ross M.?,§; Boyle, Brendan M.?; Dotson, Jennifer L.?,†
doi : 10.1097/MPG.0000000000003013
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p 563-568
Adolescents and young adults (AYAs) are at risk for disease exacerbations and increased health care utilization around the time of transition to adult care. Our aim was to identify risk factors predictive of a suboptimal transition for AYA with inflammatory bowel disease.
Moderate-to-severe Endoscopic Inflammation is Frequent After Clinical Remission in Pediatric Ulcerative Colitis
Sarbagili-Shabat, Chen?,†; Weiner, Dror?; Wardi, Joram‡; Abramas, Lee?; Yaakov, Michal?; Levine, Arie?,†
doi : 10.1097/MPG.0000000000003018
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p 569-573
Pediatric ulcerative colitis (UC) is characterized by low sustained remission rates and frequent extension of disease even if clinical remission is obtained with therapy. Moderate-to-severe endoscopic activity is a risk factor for relapse while prospective evidence regarding early mucosal healing or persistence of inflammation after remission in children is not available. Our aim was to evaluate if significant inflammation is common after clinical remission and could explain the high relapse rate in pediatric UC.
Incidence of Depression and Anxiety in a Cohort of Adolescents With Nonalcoholic Fatty Liver Disease
Noon, Sheila L.?,†; D’Annibale, Danielle A.?,‡; Schwimmer, Melanie H.?,§; Shiels, Jacqueline?,||; Arin, Jennifer?; Durelle, Janis?; Newton, Kimberly P.?,¶; Goyal, Nidhi P.?,¶; Schwimmer, Jeffrey B.?,¶
doi : 10.1097/MPG.0000000000003024
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p 579-583
To determine the incidence of clinically diagnosed depression and anxiety in adolescents with nonalcoholic fatty liver disease (NAFLD).
A Trial of an Anamnesis-based Score Applied as a Diagnostic Tool for Cow's Milk Protein Allergy in Children
Mu?oz-Urribarri, Ana?; Sabr?, Aderbal†; Sabr?, Selm?‡; Condorhuam?n, Yovani M.§
doi : 10.1097/MPG.0000000000003031
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p e86-e89
This study presents an anamnesis-based questionnaire as a diagnostic tool for cow's milk protein allergy (CMPA) in children. We applied 24 dichotomous yes/no questions to 51 cases diagnosed by oral challenge and 31 controls. All patients were recruited at the pediatric gastroenterologist outpatient practice. Patients with CMPA presented with a family history of atopy/autoimmunity, cesarean delivery, use and/or change of formulas, use of antacids/antibiotics in the first 6 months of life, an overly clean caregiver, multisystem clinical presentation, and the absence of seasonal symptoms. The CMPA group had an average score of 10.4 versus 3.2 for the control group. We identified a cut-off score of 7, which had 94.4% sensitivity and 96.9% specificity to distinguish CMPA from the control population. Cases were younger and showed different symptoms than controls. This study shows the usefulness of an anamnesis-based clinical score to guide the diagnosis of CMPA in children.
Diagnostic Accuracy of the Rome IV Criteria for the Diagnosis of Functional Gastrointestinal Disorders in Children
Velasco-Ben?tez, Carlos A.?,†; G?mez-Oliveros, Lina F.?; Rubio-Molina, Lina M.?; Tovar-Cuevas, José R.?; Saps, Miguel‡
doi : 10.1097/MPG.0000000000003030
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p 538-541
The diagnosis of functional gastrointestinal disorders (FGIDs) centers on symptoms-based criteria (Rome criteria). The last edition of the criteria was published in 2016. Still, few data on its validity support its use in children. We conducted a study aimed at determining the diagnostic accuracy of the Rome IV criteria through the application of questionnaires (Questionnaire of Pediatric Gastrointestinal Symptoms-Rome IV QPGS-IV) to diagnose FGIDs in children. We hypothesized that the Rome IV criteria has adequate diagnostic accuracy supporting its use for diagnosing FGIDs in children.
Evaluation of Nonalcoholic Fatty Liver Disease in Pediatric Patients With Inflammatory Bowel Disease
Cohen, Mallory E.?; Deepak, Parakkal†; Khanna, Geetika†,‡; Samson, Charles M.?
doi : 10.1097/MPG.0000000000003023
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p 574-578
Adult studies demonstrate the co-existence of nonalcoholic fatty liver disease (NAFLD) and inflammatory bowel disease (IBD) without traditional risk factors. Data in children with IBD are lacking. Here, we sought to establish the prevalence of NAFLD in a single-center pediatric IBD cohort, and identify potential risk factors. After institutional review board approval, we enrolled children with IBD who underwent routine abdominal magnetic resonance enterography. Proton density fat fraction (PDFF) was then estimated on magnetic resonance enterography. A total of 83 patients with IBD were identified and PDFF maps completed. Five (6%) were found to have PDFF >5%, meeting criteria for NAFLD. Compared to the patients with IBD without NAFLD, none of the evaluated risk factors including age, sex, diagnosis, time since diagnosis, medication, median alanine aminotransferase, and weight status were statistically significant. Our findings demonstrate the occult nature of NAFLD in pediatric IBD. The prevalence is not at variance with what is expected in general teenage populations.
Operational Definitions for Chronic Liver Disease Manifestations and Recurring Clinical Events in Biliary Atresia
Shiau, Henry?; Schraw, Jeremy M.†; Cavallo, Laurel?; Leung, Daniel H.?; Harpavat, Sanjiv?; Lupo, Philip J.†; Shneider, Benjamin L.?
doi : 10.1097/MPG.0000000000002992
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p 584-591
The disease course of biliary atresia (BA) may be complicated by development of chronic liver disease (CLD) manifestations (eg, ascites) and recurring clinical events (eg, cholangitis). Most pediatric CLD-manifestations/events lack standardized operational definitions, leading to inconsistent identification in clinical research. This study aimed to develop operational research definitions of CLD-manifestations/events in BA for application in retrospective analysis.
Early Motor Repertoire in Infants With Biliary Atresia: A Nationwide Prospective Cohort Study
Rodijk, Lyan H.?; Bos, Arend F.†; Verkade, Henkjan J.‡; de Kleine, Ruben H.§; Hulscher, Jan B.F.?; Bruggink, Janneke L.M.?
doi : 10.1097/MPG.0000000000003021
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p 592-596
The aim of the study was to assess the neurological status in infants with biliary atresia (BA) at time of diagnosis, using Prechtl's validated General Movement Assessment.
Management of Hepatitis-B Virus Infection in Immunocompromised Children: A Single Center Experience
Calvo, Pier Luigi?; Pinon, Michele?; Dell’Olio, Dominic†; Carpino, Andrea‡; Biasin, Eleonora§; Pizzol, Antonio?; Catalano, Silvia||; Peruzzi, Licia¶; Rigazio, Caterina?; Cisar?, Fabio?; Opramolla, Anna?; Asaftei, Sebastian Dorin§,#; Quarello, Paola§; Fagioli, Franca§
doi : 10.1097/MPG.0000000000003042
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p 597-602
The aims of the study was to expand the pediatric experience on hepatitis-B virus (HBV) reactivation, a known complication in patients with hematologic malignancies or on immunosuppression.
Dairy Fat Intake, Plasma Pentadecanoic Acid, and Plasma Iso-heptadecanoic Acid Are Inversely Associated With Liver Fat in Children
Sawh, Mary Catherine?,†; Wallace, Martina‡; Shapiro, Emma?,§; Goyal, Nidhi P.?,†; Newton, Kimberly P.?,†; Yu, Elizabeth L.?,†; Bross, Craig?; Durelle, Janis?; Knott, Cynthia||; Gangoiti, Jon A.¶; Barshop, Bruce A.¶; Gengatharan, Jivani M.‡; Meurs, Noah‡; Schlein, Alexandra#; Middleton, Michael S.#; Sirlin, Claude B.#; Metallo, Christian M.‡; Schwimmer, Jeffrey B.?,†
doi : 10.1097/MPG.0000000000003040
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p e90-e96
We sought to evaluate the relevance of pediatric dairy fat recommendations for children at risk for nonalcoholic fatty liver disease (NAFLD) by studying the association between dairy fat intake and the amount of liver fat. The effects of dairy fat may be mediated by odd chain fatty acids (OCFA), such as pentadecanoic acid (C15:0), and monomethyl branched chain fatty acids (BCFA), such as iso-heptadecanoic acid (iso-C17:0). Therefore, we also evaluated the association between plasma levels of OCFA and BCFA with the amount of liver fat.
Morphometric Changes in Children With Small Bowel Crohn Disease During Induction of Therapy: A Pilot Study
Steien, Dana B.?; Dillman, Jonathan R.†; Lopez, M. James?; Ehrlich, Peter‡; Adler, Jeremy?,§
doi : 10.1097/MPG.0000000000003009
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p 603-609
Children and adolescents with Crohn disease (CD) commonly gain weight during treatment induction, which is thought to be a marker of better health. Body composition is, however, rarely assessed at diagnosis, and changes during early treatment are not often quantified. Therefore, it is unknown if these gains are truly healthy. We sought to evaluate skeletal muscle changes during initial treatment for CD by using routine imaging.
In-hospital Growth of Very Low Birth Weight Preterm Infants: Comparative Effectiveness of 2 Human Milk Fortifiers
Kemp, Hannelie?; Becker, Piet†; Wenhold, Friedeburg Anna Maria?
doi : 10.1097/MPG.0000000000003050
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p 610-616
Amidst a high prevalence of prematurity, limited research on the growth of very low birth weight (VLBW) preterm infants and the availability of a reformulated fortifier c(RF), the study aimed to compare in-hospital growth of such infants receiving exclusively human milk fortified with either of 2 different formulations in a tertiary South African hospital.
Management of Gastrointestinal and Nutritional Problems in Children With Neurological Impairment: A Survey of Practice
Romano, Claudio?; Dipasquale, Valeria?; Van Winckel, Myriam†; Hulst, Jessie‡; Broekaert, Ilse§; Bronsky, Jiri||; Dall’Oglio, Luigi¶; Mis, Nata?a Fidler#; Hojsak, Iva??; Orel, Rok††; Papadopoulou, Alexandra‡‡; Schaeppi, Michela§§; Thapar, Nikhil||||; Wilschanski, Michael¶¶; Sullivan, Peter##; Gottrand, Frédéric???
doi : 10.1097/MPG.0000000000003020
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p e97-e101
The main aim of this study was to determine the impact on clinical practice of the first European Society of Gastroenterology, Hepatology, and Nutrition (ESPGHAN) position paper on the diagnosis and management of nutritional and gastrointestinal problems in children with neurological impairment (NI).
The Use of Fecal Calprotectin Testing in Paediatric Disorders: A Position Paper of the European Society for Paediatric Gastroenterology and Nutrition Gastroenterology Committee
Koninckx, Carmen Ribes?; Donat, Ester?; Benninga, Marc A.†; Broekaert, Ilse J.‡; Gottrand, Frederic§; Kolho, Kaija-Leena||; Lionetti, Paolo¶; Miele, Erasmo#; Orel, Rok??; Papadopoulou, Alexandra††; Pienar, Corina‡‡; Sch?ppi, Michela G.§§; Wilschanski, Michael||||; Thapar, Nikhil¶¶,##
doi : 10.1097/MPG.0000000000003046
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p 617-640
The aim of the study was to review the evidence regarding the clinical use and value of fecal calprotectin (FC) measurements in different gastrointestinal disorders in children.
Thinking Out-of-the-box: Regional Anesthesia for Early Feeding After Percutaneous Endoscopic Gastrostomy Placement
Aksu, Nihal U.?; Aksu, Can†,‡; Akay, Mustafa A.§
doi : 10.1097/MPG.0000000000003025
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p e102
Regional Anesthesia for Early Feeding After Percutaneous Endoscopic Gastrostomy Placement
Peck, Jacquelin?; Wilsey, Michael J. Jr†,‡
doi : 10.1097/MPG.0000000000003026
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p e102
Carbon Dioxide Insufflation: One Size May Not Fit Both Ends
Imseis, Essam?; Navarro, Fernando?; Hashmi, S. Shahrukh?; Thornhill, Chad†; DebRoy, Ashish‡; Rhoads, J. Marc?
doi : 10.1097/MPG.0000000000003035
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p e103
Author Response to Letter on “Is Carbon Dioxide Insufflation During Endoscopy in Children as Safe and as Effective as We Think?”
Dike, Chinenye R.?,†; Rahhal, Riad?; Bishop, Warren P.?
doi : 10.1097/MPG.0000000000003034
Journal of Pediatric Gastroenterology and Nutrition: April 2021 - Volume 72 - Issue 4 - p e103-e104
