Lubitz, Steven A. MD, MPH; Faranesh, Anthony Z. PhD; Selvaggi, Caitlin MS; Atlas, Steven J. MD, MPH; McManus, David D. MD, ScM; Singer, Daniel E. MD; Pagoto, Sherry PhD; McConnell, Michael V. MD, MSEE; Pantelopoulos, Alexandros PhD; Foulkes, Andrea S. PhD
doi : 10.1161/CIRCULATIONAHA.122.060291
Volume 146(19) pgs. 1415-1488,e257-e281 November 08, 2022
Morbidity from undiagnosed atrial fibrillation (AF) may be preventable with early detection. Many consumer wearables contain optical photoplethysmography (PPG) sensors to measure pulse rate.
Kanaoka, Koshiro MD, PhD; Onoue, Kenji MD, PhD; Terasaki, Satoshi MD, PhD; Nakano, Tomoya MD, PhD; Nakai, Michikazu PhD; Sumita, Yoko RN; Hatakeyama, Kinta MD, PhD; Terasaki, Fumio MD, PhD; Kawakami, Rika MD, PhD; Iwanaga, Yoshitaka MD, PhD; Miyamoto, Yoshihiro MD, PhD; Saito, Yoshihiko MD, PhD; on behalf of the Japanese Registry of Fulminant Myocarditis Investigators; Yuda, Satoshi; Tanno, Masaya; Takahashi, Toru; Yokoshiki, Hisashi; Toba, Masahiro; Anzai, Toshihisa; Nagai, Toshiyuki; Sato, Takuma; Takenaka, Takashi; Yamazaki, Seiji; Katagiri, Yuki; Takeuchi, Toshiharu; Sugitatsu, Kazuya; Kakinoki, Shigeo; Matsumoto, Tomoaki; Urasawa, Kazushi; Tan, Michinao; Tsujino, Ichizo; Kamigaki, Mitsunori; Tomita, Hirofumi; Hanada, Kenji; Kushibiki, Motoi; Nakamura, Akihiro; Morino, Yoshihiro; Nasu, Takahito; Yasuda, Satoshi; Suzuki, Hideaki; Iwabuchi, Kaoru; Tsuji, Kanako; Namiuchi, Shigeto; Komaru, Tatsuya; Yagi, Masahiro; Uematsu, Shoko; Takahashi, Toshiaki; Takeda, Satoru; Nakanishi, Toru; Watanabe, Masafumi; Wanezaki, Masahiro; Matsui, Motoyuki; Sugawara, Shigeo; Takeishi, Yasuchika; Oikawa, Masayoshi; Komatsu, Nobuo; Suzuki, Satoshi; Okamoto, Hiroshi; Takeyasu, Noriyuki; Akiyama, Daiki; Eki, Yutaka; Kakuta, Tsunekazu; Sugiyama, Tomoyo; Koizumi, Tomomi; Ueno, Koji; Kario, Kazuomi; Taki, Mizuri; Matsumoto, Yuri; Yasu, Takanori; Nishioka, Osamu; Naito, Shigeto; Murata, Makoto; Tange, Shoichi; Kaneko, Katsumi; Muto, Makoto; Inagaki, Hiroshi; Hasegawa, Shuichi; Tachibana, Eizo; Atsumi, Wataru; Suzuki, Masahiro; Muramatsu, Toshihiro; Yamada, Yoshihiro; Taguchi, Isao; Fukuda, Yoshiaki; Matsui, Akihiro; Kanda, Junji; Hozawa, Koji; Matsumura, Akihiko; Shimizu, Wataru; Yamamoto, Takeshi; Komuro, Issei; Hatano, Masaru; Ikeda, Takanori; Kiuchi, Shunsuke; Chikamori, Taishiro; Takei, Yasuyoshi; Soejima, Kyoko; Minamishima, Toshinori; Tanaka, Hiroyuki; Shimizu, Shigeo; Kasao, Masashi; Kadohira, Tadayuki; Minamino, Tohru; Shimada, Kazunori; Iwata, Hiroshi; Momiyama, Yukihiko; Ashikaga, Takashi; Nozato, Toshihiro; Fujiwara, Yasumasa; Inoue, Kenji; Sasano, Tetsuo; Matsuda, Junji; Ishii, Yasuhiro; Ono, Yuichi; Tanabe, Kengo; Horiuchi, Yu; Shinke, Toshiro; Kodama, Yusuke; Moroi, Masao; Yazaki, Yoshiyuki; Mizumura, Taisuke; Ohta, Hiroshi; Akashi, Yoshihiro; Kotoku, Nozomi; Ikari, Yuji; Maruyama, Mitsunori; Sato, Yasuhiro; Tamura, Koichi; Konishi, Masaaki; Suzuki, Hiroshi; Ebato, Mio; Fukui, Kazuki; Yumoto, Kazuhiko; Iwasawa, Takamasa; Kashimura, Takeshi; Takahashi, Kazuyoshi; Okada, Yoshinobu; Kaku, Bunji; Usuda, Kazuo; Maruyama, Michiro; Kameyama, Tomoki; Higashikata, Toshinori; Hodatsu, Akihiko; Osato, Kazuo; Nagata, Yoji; Maeno, Koji; Satake, Kazuo; Sawanobori, Takao; Watanabe, Noboru; Kuwahara, Koichiro; Motoki, Hirohiko; Kitabayashi, Hiroshi; Otagiri, Kyuhachi; Kono, Tsunesuke; Yamagishi, Daisuke; Yazaki, Yoshikazu; Noda, Toshiyuki; Morishima, Itsuro; Watanabe, Naoki; Tanaka, Shinichiro; Onodera, Tomoya; Nawada, Ryuzo; Watanabe, Akinori; Matsunaga, Masaki; Suwa, Satoru; Sakamoto, Hiroshi; Sakamoto, Hiroki; Aoyama, Takeshi; Kanamori, Norio; Muto, Masahiro; Maekawa, Yuichiro; Ohtani, Hayato; Ozaki, Yukio; Naruse, Kenshin; Takemoto, Kenji; Kamiya, Haruo; Suzuki, Takeshi; Tomita, Yasushi; Suzuki, Susumu; Kametani, Ryosuke; Aoyama, Hidekazu; Osanai, Hiroyuki; Harada, Ken; Kada, Kenji; Saeki, Tomoaki; Kobayashi, Koichi; Ogawa, Yasuhiro; Terasawa, Akihiro; Shinoda, Masanori; Oguri, Mitsutoshi; Shimizu, Kiyokazu; Sawamura, Akinori; Sugiura, Atsushi; Hattori, Kosuke; Mokuno, Shinji; Kondo, Kazuhisa; Dohi, Kaoru; Moriwaki, Keishi; Kasai, Atsunobu; Nakakuki, Tetsuya; Kaitani, Kazuaki; Jinnai, Toshikazu; Yamamoto, Takashi; Kurata, Hiroyuki; Wada, Atsuyuki; Akao, Masaharu; Hamatani, Yasuhiro; Ishibashi, Kazuya; Akakabe, Yoshiki; Asaumi, Yasuhide; Matama, Hideo; Sakata, Yasushi; Kioka, Hidetaka; Takaishi, Hiroshi; Iwanaga, Yoshitaka; Takase, Toru; Matsuda, Mitsuo; Sato, Fumi; Hasegawa, Shinji; Ishigami, Kenichi; Ichikawa, Minoru; Takagi, Takashi; Inoko, Moriaki; Hoshiga, Masaaki; Fujita, Shuichi; Takeda, Yoshihiro; Kawarabayashi, Takahiko; Takaoka, Hideyuki; Nakajima, Kenji; Yuguchi, Tadashi; Kawasaki, Tatsuya; Shinoda, Yukinori; Sato, Yukihito; Ishihara, Masaharu; Matsumoto, Yuki; Kawai, Hiroya; Takaya, Tomofumi; Matsuo, Kouki; Mano, Toshiaki; Hirata, Kenichi; Hisamatsu, Eriko; Inoue, Nobutaka; Tamita, Koichi; Mukohara, Naoki; Shimoyama, Hisashi; Miyajima, Toru; Tamura, Toshihiro; Tamaki, Yodo; Suzuki, Megumi; Yokota, Ryoji; Horii, Manabu; Yamanaka, Kazuo; Kawata, Hiroyuki; Hashimoto, Yukihiro; Nakada, Yasuki; Nakagawa, Hitoshi; Ueda, Tomoya; Nishida, Taku; Seno, Ayako; Watanabe, Makoto; Akasaka, Takashi; Tanimoto, Takashi; Toyofuku, Mamoru; Yamamoto, Kazuhiro; Kinugasa, Yoshiharu; Hirai, Masayuki; Nasu, Hiroshi; Shirota, Kinya; Oda, Tsuyoshi; Oka, Takefumi; Kadota, Kazushige; Ohya, Masanobu; Ito, Hiroshi; Nakamura, Kazufumi; Ogura, Soichiro; Fuke, Soichiro; Uemura, Shiro; Matsubara, Hiromi; Watanabe, Atsuyuki; Morishima, Nobuyuki; Kihara, Yasuki; Hidaka, Takayuki; Ueda, Hironori; Ono, Yujiro; Muraoka, Yuji; Hatanari, Miyo; Miyamoto, Yoshinori; Dote, Keigo; Kato, Masaya; Yano, Masafumi; Mochizuki, Mamoru; Ikeda, Yasuhiro; Fujinaga, Hiroyuki; Hosokawa, Shinobu; Sata, Masataka; Yamaguchi, Koji; Aki, Naoko; Minamino, Tetsuo; Miyake, Yuichi; Takagi, Yuichiro; Doi, Masayuki; Taketani, Yoshio; Okayama, Hideki; Shigematsu, Tatsuya; Higaki, Akinori; Yamaguchi, Osamu; Inaba, Shinji; Ikeda, Shuntaro; Kawai, Kazuya; Kitaoka, Hiroaki; Kubo, Toru; Ando, Kenji; Inui, Kaoru; Fukumoto, Yoshihiro; Hori, Kensuke; Homma, Takehiro; Kawasaki, Tomohiro; Mohri, Masahiro; Fujiwara, Masaki; Tsutsui, Hiroyuki; Ide, Tomomi; Miura, Shin-Ichiro; Kuwano, Takashi; Shimomura, Hideki; Kadokami, Toshiaki; Taba, Masanao; Kondou, Katsuhiro; Kubota, Toru; Nagatomo, Daisuke; Mukai, Yasushi; Matsukawa, Ryuichi; Tashiro, Hideki; Shimomura, Mitsuhiro; Maemura, Koji; Kawano, Hiroaki; Oku, Koji; Yamasa, Toshihiko; Kizaki, Yoshihisa; Sakamoto, Tomohiro; Tamura, Yudai; Ito, Teruhiko; Fujimoto, Kazuteru; Tsujita, Kenichi; Takashio, Seiji; Kurokawa, Hirofumi; Takahashi, Naohiko; Saito, Shotaro; Arikawa, Masaya; Shibata, Yoshisato; Nishihira, Kensaku; Tsuruda, Toshihiro; Sonoda, Masahiro; Atsuchi, Nobuhiko; Ohishi, Mitsuru; Higuchi, Koji; Miyata, Masaaki; Oketani, Naoya; Akimoto, Yoshinori; Asahi, Tomohiro; Wake, Minoru
doi : 10.1161/CIRCULATIONAHA.121.058869
Fulminant myocarditis presentation (FMP) is a rare and severe presentation of myocarditis. The natural history of FMP and its clinical features associated with poor outcomes are incompletely understood because there is a lack of generalizable evidence.
Gasperetti, Alessio MD; Carrick, Richard T. MD; Costa, Sarah MD; Compagnucci, Paolo MD; Bosman, Laurens P. MD; Chivulescu, Monica MD; Tichnell, Crystal MGC, RN; Murray, Brittney MS; Tandri, Harikrishna MD; Tadros, Rafik MD, PhD; Rivard, Lena MD; van den Berg, Maarten P. MD, PhD; Zeppenfeld, Katja MD, PhD; Wilde, Arthur A.M. MD, PhD; Pompilio, Giulio MD; Carbucicchio, Corrado MD; Dello Russo, Antonio MD, PhD; Casella, Michela MD, PhD; Svensson, Anneli MD, PhD; Brunckhorst, Corinna B. MD; van Tintelen, J. Peter MD, PhD; Platonov, Pyotr G. MD, PhD; Haugaa, Kristina H. MD, PhD; Duru, Firat MD; te Riele, Anneline S.J.M. MD, PhD; Khairy, Paul MD, PhD; Tondo, Claudio MD, PhD; Calkins, Hugh MD; James, Cynthia A. PhD; Saguner, Ardan M. MD ,*; Cadrin-Tourigny, Julia MD *,
doi : 10.1161/CIRCULATIONAHA.122.060866
A novel risk calculator based on clinical characteristics and noninvasive tests that predicts the onset of clinical sustained ventricular arrhythmias (VA) in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) has been proposed and validated by recent studies.
Ma, Qian PhD; Yang, Qiuhua PhD; Xu, Jiean PhD; Zhang, Xiaoyu PhD; Kim, David BA; Liu, Zhiping PhD; Da, Qingen PhD; Mao, Xiaoxiao MS; Zhou, Yaqi PhD; Cai, Yongfeng MS; Pareek, Vidhi PhD; Kim, Ha Won PhD; Wu, Guangyu PhD; Dong, Zheng PhD; Song, Wen-Liang MD; Gan, Lin PhD; Zhang, Chunxiang MD, PhD; Hong, Mei PhD; Benkovic, Stephen J. PhD; Weintraub, Neal L. MD; Fulton, David Jr PhD; Asara, John M. PhD; Ben-Sahra, Issam PhD; Huo, Yuqing MD, PhD
doi : 10.1161/CIRCULATIONAHA.121.058901
Proliferation of vascular smooth muscle cells (VSMCs) is a hallmark of arterial diseases, especially in arterial restenosis after angioplasty or stent placement. VSMCs reprogram their metabolism to meet the increased requirements of lipids, proteins, and nucleotides for their proliferation. De novo purine synthesis is one of critical pathways for nucleotide synthesis.
Brandes, Axel MD ,*; Stavrakis, Stavros MD, PhD ,*; Freedman, Ben MD; Antoniou, Sotiris MSc; Boriani, Giuseppe MD; Camm, A. John MD; Chow, Clara K. MD, PhD; Ding, Eric BS; Engdahl, Johan MD; Gibson, Michael M. MD; Golovchiner, Gregory MD; Glotzer, Taya MD; Guo, Yutao MD; Healey, Jeff S. MD, MSc; Hills, Mellanie T. CSP; Johnson, Linda MD; Lip, Gregory Y. H. MD; Lobban, Trudie MBE; Macfarlane, Peter W. PhD; Marcus, Gregory M. MD, MAS; McManus, David D. MD; Neubeck, Lis PhD; Orchard, Jessica PhD, MPH; Perez, Marco V. MD; Schnabel, Renate B. MD, PhD; Smyth, Breda MPH; Steinhubl, Steven MD; Turakhia, Mintu P. MD
doi : 10.1161/CIRCULATIONAHA.121.058911
AB The technological evolution and widespread availability of wearables and handheld ECG devices capable of screening for atrial fibrillation (AF), and their promotion directly to consumers, has focused attention of health care professionals and patient organizations on consumer-led AF screening.
Han, Jingnan MD, MSc; Husband, Graham MD; Doppalapudi, Harish MD
D'Souza, Andrew W. MSc; Yoo, Jeung-Ki PhD; Takeda, Ryosuke PhD; Badrov, Mark B. PhD; Anderson, Elizabeth H. PhD; Washio, Takuro PhD; North, Carol S. MD; Suris, Alina PhD; Nelson, Michael D. PhD; Shoemaker, J. Kevin PhD; Fu, Qi MD, PhD
Shetty, Naman S. MD; Parcha, Vibhu MD; Hasnie, Ammar MD; Pandey, Ambarish MD, MSCS; Arora, Garima MD; Arora, Pankaj MD
Agirbasli, Mehmet MD; Aksoy, Alperen MD
Bularga, Anda MD; Mills, Nicholas L. MD; Chapman, Andrew R. MD
Moise, Nathalie MD, MS, FAHA, Chair; Cene, Crystal W. MD, MPH, FAHA, Vice Chair; Tabak, Rachel G. PhD, RD; Young, Deborah R. PhD, FAHA; Mills, Katherine T. PhD; Essien, Utibe R. MD, MPH; Anderson, Cheryl A.M. PhD, MPH, FAHA; Lopez-Jimenez, Francisco MD, MSc, FAHA; on behalf of the American Heart Association Council on Epidemiology and Prevention; Council on Hypertension; and Stroke Council
doi : 10.1161/CIR.0000000000001096
AB Reducing cardiovascular disease disparities will require a concerted, focused effort to better adopt evidence-based interventions, in particular, those that address social determinants of health, in historically marginalized populations (ie, communities excluded on the basis of social identifiers like race, ethnicity, and social class and subject to inequitable distribution of social, economic, physical, and psychological resources).
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