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Rate Versus Rhythm Control for Atrial Fibrillation: Has the Debate Been Settled?.
Prystowsky, Eric N. MD
doi : 10.1161/CIRCULATIONAHA.122.060243
Volume 146(21) pgs. 1561-1640,e299-e324 November 22, 2022
Efficacy of a Drug-Eluting Stent Versus Bare Metal Stents for Symptomatic Femoropopliteal Peripheral Artery Disease: Primary Results of the EMINENT Randomized Trial.
Goueffic, Yann MD, PhD; Torsello, Giovanni MD; Zeller, Thomas MD; Esposito, Giovanni MD; Vermassen, Frank MD; Hausegger, Klaus Armin MD; Tepe, Gunnar MD; Thieme, Marcus MD; Gschwandtner, Michael MD; Kahlberg, Andrea MD; Schindewolf, Marc MD; Sapoval, Marc MD; Diaz-Cartelle, Juan MD; Stavroulakis, Konstantinos MD; on behalf of the EMINENT Investigators; Apruzzi, Luca; Baccellieri, Domenico; Bea, Florian; Becquemin, Jean-Pierre; Bent, Clare; Bertoglio, Luca; Bianchini, Aurelia; Bieri, Thomas; Blessing, Erwin; Chaillou, Phillipe; Chiesa, Roberto; Del Giudice, Costantino; Deloose, Koen; Desgranges, Pascal; Erbel, Christian; Espinola-Klein, Christine; Esposito, Giovanni; Feugier, Patrick; Fourneau, Inge; Grozinger, Gerd; Gschwandtner, Michael; Guillemot, Loic; Hamady, Mohammed; Hausegger, Klaus Armin; Heilmeier, Britta; Hendriks, Jeroen; Jaffer, Ounali; Kahlberg, Andrea; Kakani, Nirmal; Keirse, Koen; Kranewitter, Christof; Krokidis, Miltaidis; Langhoff, Ralf; Lee, Michael; Lohle, Paul; Maene, Lieven; Mahnken, Andreas; Maiwald, Lars; Mascia, Daniele; Melloni, Andrea; Montorsi, Piero; Nice, Colin; Oberhuber, Alexander; Paetzel, Christian; Ramjas, Greg; Rammos, Christos; Rinaldi, Enrico; Rosset, Eugenio; Ruiz Salmeron, Rafael; Sapoval, Marc; Saracino, Concetta; Sauguet, Antoine; Schafer, Jost Phillipp; Schahab, Nadjib; Schindewolf, Marc; Settembre, Nicola; Simonini, Elisa; Sobocinski, Jonathan; Steinmetz, Eric; Tepe, Gunnar; Thaveau, Fabien; Thieme, Marcus; Torsello, Giovanni; van Overhagen, Hans; Vermassen, Frank; Verbist, Jurgen; Zeller, Thomas; Zorger, Niels
doi : 10.1161/CIRCULATIONAHA.122.059606
A clear patency benefit of a drug-eluting stent (DES) over bare metal stents (BMSs) for treating peripheral artery disease of the femoropopliteal segment has not been definitively demonstrated.
From IMPERIALism to EMINENence: The Noble Rise of the Second-Generation Peripheral Drug-Eluting Stent.
Mosarla, Ramya C. MD; Secemsky, Eric A. MD, MSc
Everolimus-Eluting Stents or Bypass Surgery for Multivessel Coronary Artery Disease: Extended Follow-Up Outcomes of Multicenter Randomized Controlled BEST Trial.
Ahn, Jung-Min MD ,*; Kang, Do-Yoon MD ,*; Yun, Sung-Cheol PhD; Ho Hur, Seung MD; Park, Hun-Jun MD; Tresukosol, Damras MD; Chol Kang, Woong MD; Moon Kwon, Hyuck MD; Rha, Seung-Woon MD; Lim, Do-Sun MD; Jeong, Myung-Ho MD; Lee, Bong-Ki MD; Huang, He MD; Hyo Lim, Young MD; Ho Bae, Jang MD; Ok Kim, Byung MD; Kiam Ong, Tiong MD; Gyun Ahn, Sung MD; Chung, Cheol-Hyun MD; Park, Duk-Woo MD; Park, Seung-Jung MD, PhD; for the BEST Extended Follow-Up Study Investigators; Ahn, Jung-Min; Kang, Do-Yoon; Yun, Sung-Cheol; Park, Duk-Woo; Chung, Cheol-Hyun; Park, Seung-Jung; Ho Hur, Seung; Park, Hun-Jun; Tresukosol, Damras; Kang, Woong Chol; Kwon, Hyuck Moon; Lim, Do-Sun; Rha, Seung-Woon; Jeong, Myung-Ho; Lee, Bong-Ki; Huang, He; Lim, Young Hyo; Bae, Jang Ho; Kim, Byung Ok; Ong, Tiong Kiam; Ahn, Sung Gyun; Yang, Tae-Hyun; Kim, Byeong-Keuk; Jang, Ji-Yong; Park, Jong-Seon; Ge, JunBo; Lee, Sung Yun; Kim, Jun-Hong; Cho, Jang-Hyun; Choi, Yun Seok; Park, Gyung-Min; Zambahari, Robaaya
doi : 10.1161/CIRCULATIONAHA.122.062188
Long-term comparative outcomes after percutaneous coronary intervention (PCI) with everolimus-eluting stents and coronary artery bypass grafting (CABG) are limited in patients with multivessel coronary artery disease.
Nuclear Receptor NR1D1 Regulates Abdominal Aortic Aneurysm Development by Targeting the Mitochondrial Tricarboxylic Acid Cycle Enzyme Aconitase-2.
Sun, Ling-Yue MS ,*; Lyu, Yu-Yan MD, PhD ,*; Zhang, Heng-Yuan MS; Shen, Zhi BS; Lin, Guan-Qiao BS; Geng, Na BS; Wang, Yu-Li BS; Huang, Lin PhD; Feng, Ze-Hao MS; Guo, Xiao PhD; Lin, Nan MS; Ding, Song MD, PhD; Yuan, An-Cai MD, PhD; Zhang, Lan MD, PhD; Qian, Kun PhD; Pu, Jun MD, PhD
doi : 10.1161/CIRCULATIONAHA.121.057623
Metabolic disorder increases the risk of abdominal aortic aneurysm (AAA). NRs (nuclear receptors) have been increasingly recognized as important regulators of cell metabolism. However, the role of NRs in AAA development remains largely unknown.
Defective Desmosomal Adhesion Causes Arrhythmogenic Cardiomyopathy by Involving an Integrin-[alpha]V[beta]6/TGF-[beta] Signaling Cascade.
Schinner, Camilla MD; Xu, Lifen PhD; Franz, Henriette PhD; Zimmermann, Aude MSc; Wanuske, Marie-Theres MSc; Rathod, Maitreyi PhD; Hanns, Pauline PhD; Geier, Florian PhD; Pelczar, Pawel PhD; Liang, Yan PhD; Lorenz, Vera MSc; Studle, Chiara PhD; Maly, Piotr I. PhD; Kauferstein, Silke PhD; Beckmann, Britt M. MD; Sheikh, Farah PhD; Kuster, Gabriela M. MD; Spindler, Volker MD
doi : 10.1161/CIRCULATIONAHA.121.057329
Arrhythmogenic cardiomyopathy (ACM) is characterized by progressive loss of cardiomyocytes with fibrofatty tissue replacement, systolic dysfunction, and life-threatening arrhythmias.
Increasing Societal Benefit From Cardiovascular Drugs.
Tonelli, Marcello MD, SM, MSc; Straus, Sharon MD, MSc, HBSc
doi : 10.1161/CIRCULATIONAHA.122.059032
AB During the past few years, several innovative treatments for noncommunicable chronic disease have become available, including SGLT2i (sodium-glucose cotransporter-2 inhibitors), GLP-1a (glucagon-like-peptide 1 agonists), ARNI (angiotensin receptor-neprilysin inhibitors), and finerenone, a selective nonsteroidal mineralocorticoid receptor antagonist. Each of these medications improves clinically relevant outcomes when added to existing therapies, and the indications for their use are rapidly expanding.
Fitness-Rather Than BMI-Appears to Be a Better Predictor of Survival for Women With Heart Disease.
Kuehn, Bridget M.
Association Between Sacubitril/Valsartan Initiation and Mitral Regurgitation Severity in Heart Failure With Reduced Ejection Fraction: The PROVE-HF Study.
Januzzi, James L. MD; Omar, Alaa Mabrouk Salem MD, MSc, PhD; Liu, Yuxi MS; Murphy, Sean MBBCh; Butler, Javed MD, MBA; Felker, G. Michael MD, MHS; Pina, Iliana L. MD, MPH; Ward, Jonathan PharmD; Solomon, Scott MD; Contreras, Johanna MD
Emerging Evidence on Coronary Heart Disease Screening in Kidney and Liver Transplantation Candidates: A Scientific Statement From the American Heart Association.
Cheng, Xingxing S. MD, MS, Chair; VanWagner, Lisa B. MD, MS; Costa, Salvatore P. MD; Axelrod, David A. MD, MBA; Bangalore, Sripal MD, MHA, FAHA; Norman, Silas P. MD; Herzog, Charles A. MD, FAHA; Lentine, Krista L. MD, PhD, Vice Chair; on behalf of the American Heart Association Council on the Kidney in Cardiovascular Disease and Council on Cardiovascular Radiology and Intervention
doi : 10.1161/CIR.0000000000001104
AB Coronary heart disease is an important source of mortality and morbidity among kidney transplantation and liver transplantation candidates and recipients and is driven by traditional and nontraditional risk factors related to end-stage organ disease.
