Probiotics and Antimicrobial Proteins




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سفارش

Could the COVID-19-Driven Increased Use of Ivermectin Lead to Incidents of Imbalanced Gut Microbiota and Dysbiosis?

Leon M. T. Dicks, Shelly M. Deane & Matthew J. Grobbelaar 

doi : 10.1007/s12602-022-09925-5

The microfilaricidal anthelmintic drug ivermectin (IVM) has been used since 1988 for treatment of parasitic infections in animals and humans.

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Evaluation of the Role of Probiotics As a New Strategy to Eliminate Microbial Toxins: a Review

Abdolamir Ghadaksaz, Somayeh Mousavi Nodoushan, Hamid Sedighian, Elham Behzadi & Abbas Ali Imani Fooladi 

doi : 10.1007/s12602-021-09893-2

Probiotics are living microorganisms that have favorable effects on human and animal health. The most usual types of microorganisms recruited as probiotics are lactic acid bacteria (LAB) and bifidobacteria.

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Bacteriocins Produced by LAB Isolated from Cheeses within the Period 2009–2021: a Review

Lorena Trejo-González, Ana-Estefanía Gutiérrez-Carrillo, Adriana-Inés Rodríguez-Hernández, Ma. del Rocío López-Cuellar & Norberto Chavarría-Hernández 

doi : 10.1007/s12602-021-09825-0

A survey is presented concerning original research articles published in well-reputed scientific journals on the isolation of lactic acid bacteria (LAB) from cheeses worldwide, where researchers evaluated the bacteriocin production by such isolates in searching for novel functional peptides that can exhibit potential for biotechnological applications.

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Probiotic Potential and Effects on Gut Microbiota Composition and Immunity of Indigenous Gut Lactobacilli in Apis cerana

Mingkui Lv, Sifan Wang, Huajuan Yin, Kun Dong, Yiqiu Liu, Hongbin Pan, Qiuye Lin & Zhenhui Cao 

doi : 10.1007/s12602-022-09935-3

This study aimed to investigate the probiotic potential of gut indigenous lactic acid bacteria (LAB) originated from Apis cerana. Six Limosilactobacillus reuteri and one Lactobacillus helveticus were isolated from gut samples of A.

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Designing Anti-Microbial Peptides Against Major β-Lactamase Enzymes in Clinically Important Gram-Negative Bacterial Pathogens: An In-Silico Study

Soumya Basu, Sahil Mandar Joshi, Sudha Ramaiah & Anand Anbarasu 

doi : 10.1007/s12602-022-09929-1

Anti-microbial resistance (AMR) creating healthcare concerns worldwide requires ardent exploration of therapeutic alternatives. Although anti-microbial peptides (AMP) are popular for broad-spectrum activity, recent evidence of increasing resistance to membrane-acting AMPs by ESKAPE pathogens has compelled us to design novel AMPs as therapeutic candidates.

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A Biofloc-Based Aquaculture System Bio-augmented with Probiotic Bacteria Bacillus tequilensis AP BFT3 Improves Culture Environment, Production Performances, and Proteomic Changes in Penaeus vannamei

A. Panigrahi, P. Esakkiraj, C. Saranya, R. R. Das, M. Sundaram, N. S. Sudheer, I. F. Biju & M. Jayanthi 

doi : 10.1007/s12602-022-09926-4

Experiments were conducted to evaluate the probiotic effect of bio-augmented Bacillus tequilensis AP BFT3 on improving production, immune response, and proteomic changes of Penaeus vannamei reared in a biofloc system.

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Compositional Quality and Possible Gastrointestinal Performance of Marketed Probiotic Supplements

Ghazal Aziz, Arsalan Zaidi & Muhammad Tariq 

doi : 10.1007/s12602-022-09931-7

The local pharmacies and shops are brimming with various probiotic products that herald a range of health benefits.

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Comparison Between Different Delivery Vehicles for the Probiotic Bifidobacterium animalis subsp. lactis HN019 on Experimental Periodontitis in Rats

Luiz F. F. Oliveira, Giselle Aparecida da Silva, Pedro H. F. Silva, André Luis Gomes Moreira, Sérgio L. Salvador, Adriano Gomes da Cruz, Michel R. Messora & Flávia A. C. Furlaneto 

doi : 10.1007/s12602-022-09930-8

This study aimed to assess the effects of the probiotic (PROB) Bifidobacterium animalis subsp. lactis HN019 in two different delivery vehicles in experimental periodontitis (EP), including the gene expression for IL-10, IFN-γ, and FOXP3.

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Isolation and Chemical Characterization of an Alpha-Helical Peptide, Dendrocin-ZM1, Derived from Zataria multiflora Boiss with Potent Antibacterial Activity

Sima Sadat Seyedjavadi, Mehdi Razzaghi-Abyaneh, Mohammad Javad Nasiri, Ali Hashemi, Hossein Goudarzi, Mehrdad Haghighi, Masoud Dadashi, Mehdi Goudarzi, Hadi Zare-Zardini & Behzad Pourhossein 

doi : 10.1007/s12602-022-09907-7

Today, resistance of microorganisms to antibiotics has become a major challenge. To overcome this problem, development of new drugs, besides research on their antibacterial activity, is essential.

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Probiotic Characteristics of Lactiplantibacillus Plantarum N-1 and Its Cholesterol-Lowering Effect in Hypercholesterolemic Rats

Lei Tian, Rongmei Liu, Zhiwei Zhou, Xiaofang Xu, Su Feng, Ariel Kushmaro, Robert S. Marks, Dan Wang & Qun Sun 

doi : 10.1007/s12602-021-09886-1

In this study, the probiotic potential and treatment effects of Lactiplantibacillus plantarum N-1 in hypercholesterolemic rats were investigated, and the possible regulatory mechanisms of lipid metabolism via short-chain fatty acids (SCFAs) and 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase were elucidated.

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Potentially Probiotic Limosilactobacillus fermentum Fruit-Derived Strains Alleviate Cardiometabolic Disorders and Gut Microbiota Impairment in Male Rats Fed a High-Fat Diet

Georgianna de Araújo Henriques Ferreira, Marciane Magnani, Lucélia Cabral, Larissa Ramalho Brandão, Melline Fontes Noronha, Josiane de Campos Cruz, Evandro Leite de Souza & José Luiz de Brito Alves 

doi : 10.1007/s12602-021-09889-y

High-fat diet (HFD) consumption is a risk factor for dyslipidemias, insulin resistance, and arterial hypertension linked with gut dysbiosis. Probiotic administration has been suggested as a safe therapeutic strategy for gut microbiota modulation and treatment and/or prevention of cardiometabolic disorders.

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Biofunctional Attributes of Surface Layer Protein and Cell-Bound Exopolysaccharide from Probiotic Limosilactobacillus fermentum (MTCC 5898)

Shalaka Bhawal, Ankita Kumari, Suman Kapila & Rajeev Kapila 

doi : 10.1007/s12602-021-09891-4

The probiotic extracellular matrix components (ECM) have been considered as an important factor in eliciting the beneficial roles of the bacteria. The study involved the growth phase–dependent extraction of the surface layer protein (SLP) and cell-bound exopolysaccharide (EPS-b) from novel Limosilactobacillus fermentum (MTCC 5898). Both SLP and EPS-b were optimally extracted at the late logarithmic phase of the bacteria upon 8 h of incubation.

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Supplementation of Bacillus sp. DU-106 Alleviates Antibiotic-Associated Diarrhea in Association with the Regulation of Intestinal Microbiota in Mice

Darong Huang, Yanlan Chen, Hongzhu Chen, Xinyu Deng, Jianzhao Huang, Siming Lu, Pan Li & Bing Du 

doi : 10.1007/s12602-022-09906-8

Bacillus sp. DU-106, a potential probiotic, has been proved to activate innate immunity, reduce hypercholesterolemia, and regulate the gut microbiota of mice. In the present study, we investigated the therapeutic effect of strain DU-106 in antibiotic-associated diarrhea (AAD) via analyzing the changes in gut microbial composition in mice.

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Prevention of Recurrent Childhood Caries with Probiotic Supplements: A Randomized Controlled Trial with a 12-Month Follow-Up

P. Hasslöf, L. Granqvist, C. Stecksén-Blicks & S. Twetman 

doi : 10.1007/s12602-022-09913-9

The aim of this study was to evaluate the effect of drops containing probiotic bacteria on the recurrence of dental caries in preschool children. The study employed a randomized, placebo-controlled, double-blinded design with two parallel arms.

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Serum Stable and Low Hemolytic Temporin-SHa Peptide Analogs Disrupt Cell Membrane of Methicillin-Resistant Staphylococcus aureus (MRSA)

Rukesh Maharjan, Arif Iftikhar Khan, Muhammad Nadeem-ul-Haque, Marc Maresca, M. Iqbal Choudhary, Farzana Shaheen & Shabana U. Simjee 

doi : 10.1007/s12602-022-09915-7

Anti-microbial peptides (AMPs) have attracted major attention due to their potential bio-activities against some multidrug resistant pathogens. The present study evaluated the mechanism of actions of highly potent AMP temporin-SHa analogs, i.e., [G4a]-SHa, [G7a]-SHa, and [G10a]-SHa, against methicillin-resistant Staphylococcus aureus (MRSA) NCTC (13277) with minimum inhibitory concentrations (MICs) of 14.35, 7.16, and 3.58 µM, respectively.

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